Lillian Chong
@ltchong.bsky.social
Professor @pittchem.bsky.social. Computational biophysicist, leading @westpasoftware.bsky.social development for weighted ensemble rare-event sampling, Amber force field developer.
Reposted by Lillian Chong
Come and work with us in Bristol Chemistry, ranked #1 in the UK for research. We’re seeking outstanding candidates in:
Engineering biology
Synthetic biology
Chemical biology
Biophysics or biophysical tools
Biocatalysis
www.bristol.ac.uk/jobs/find/de...
Engineering biology
Synthetic biology
Chemical biology
Biophysics or biophysical tools
Biocatalysis
www.bristol.ac.uk/jobs/find/de...
Details | Working at Bristol | University of Bristol
www.bristol.ac.uk
August 30, 2025 at 2:11 PM
Come and work with us in Bristol Chemistry, ranked #1 in the UK for research. We’re seeking outstanding candidates in:
Engineering biology
Synthetic biology
Chemical biology
Biophysics or biophysical tools
Biocatalysis
www.bristol.ac.uk/jobs/find/de...
Engineering biology
Synthetic biology
Chemical biology
Biophysics or biophysical tools
Biocatalysis
www.bristol.ac.uk/jobs/find/de...
Reposted by Lillian Chong
This is a good watch. So much potentially impactful science is being stopped for no good reason.
New York Times story with profiles of researchers whose grants were terminated.
[Gift Link]
www.nytimes.com/2025/08/24/o...
[Gift Link]
www.nytimes.com/2025/08/24/o...
Opinion | America First? Not When It Comes to Your Health.
www.nytimes.com
August 24, 2025 at 2:12 PM
This is a good watch. So much potentially impactful science is being stopped for no good reason.
Reposted by Lillian Chong
Reposted by Lillian Chong
Reposted by Lillian Chong
Reposted by Lillian Chong
Did you know about the BPS Bridging Funds Program?
If you're a biophysicist navigating a difficult time, this program is for you to defray costs for attending the BPS Annual Meeting!
I am grateful to the @biophysicalsoc.bsky.social for supporting our members!
www.biophysics.org/2026meeting/...
If you're a biophysicist navigating a difficult time, this program is for you to defray costs for attending the BPS Annual Meeting!
I am grateful to the @biophysicalsoc.bsky.social for supporting our members!
www.biophysics.org/2026meeting/...
BPS2026 Travel Awards | Biophysical Society
www.biophysics.org
July 25, 2025 at 3:19 PM
Did you know about the BPS Bridging Funds Program?
If you're a biophysicist navigating a difficult time, this program is for you to defray costs for attending the BPS Annual Meeting!
I am grateful to the @biophysicalsoc.bsky.social for supporting our members!
www.biophysics.org/2026meeting/...
If you're a biophysicist navigating a difficult time, this program is for you to defray costs for attending the BPS Annual Meeting!
I am grateful to the @biophysicalsoc.bsky.social for supporting our members!
www.biophysics.org/2026meeting/...
Reposted by Lillian Chong
Summary Table of the massive defunding of biomedical research in the United States
www.nytimes.com/interactive/...
www.nytimes.com/interactive/...
July 6, 2025 at 3:13 PM
Summary Table of the massive defunding of biomedical research in the United States
www.nytimes.com/interactive/...
www.nytimes.com/interactive/...
Reposted by Lillian Chong
Out of the 356 drugs that were approved by the FDA from 2010-2019, NIH funding contributed to 354 of them, totaling $187 billion, only 2 were privately funded. From the NYTimes www.nytimes.com/interactive/...
June 30, 2025 at 12:56 PM
Out of the 356 drugs that were approved by the FDA from 2010-2019, NIH funding contributed to 354 of them, totaling $187 billion, only 2 were privately funded. From the NYTimes www.nytimes.com/interactive/...
Reposted by Lillian Chong
Exclusive: An international scientific competition widely credited with spurring the development of artificial intelligence for biology appears to be on its deathbed. scim.ag/44ukS90
Exclusive: Famed protein structure competition nears end as NIH grant money runs out
Agency silent on funding renewal for contest that inspired creation of AIs that predicted how proteins would fold
scim.ag
July 2, 2025 at 10:00 PM
Exclusive: An international scientific competition widely credited with spurring the development of artificial intelligence for biology appears to be on its deathbed. scim.ag/44ukS90
Reposted by Lillian Chong
Reposted by Lillian Chong
This article says all you need to know about why basic science is the lifeblood of innovation. It’s the long game but there remains no substitute.
Also a favorite example of @jeremymberg.bsky.social
The Radical Development of an Entirely New Painkiller www.newyorker.com/magazine/202...
Also a favorite example of @jeremymberg.bsky.social
The Radical Development of an Entirely New Painkiller www.newyorker.com/magazine/202...
The Radical Development of an Entirely New Painkiller
The opioid crisis has made it even more urgent to come up with novel approaches to treating suffering. Finally there’s something effective.
www.newyorker.com
June 5, 2025 at 11:49 AM
This article says all you need to know about why basic science is the lifeblood of innovation. It’s the long game but there remains no substitute.
Also a favorite example of @jeremymberg.bsky.social
The Radical Development of an Entirely New Painkiller www.newyorker.com/magazine/202...
Also a favorite example of @jeremymberg.bsky.social
The Radical Development of an Entirely New Painkiller www.newyorker.com/magazine/202...
Reposted by Lillian Chong
ATTENTION: NSF GRANT RECIPIENTS
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
a cartoon of a man holding a frying pan and a spoon with red alert written above him
ALT: a cartoon of a man holding a frying pan and a spoon with red alert written above him
media.tenor.com
April 24, 2025 at 9:09 PM
ATTENTION: NSF GRANT RECIPIENTS
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
Reposted by Lillian Chong
✨ Check out @mackevinbraza.bsky.social 's new work on full length APOBEC3B, which shows how the NTD modulates active site opening in the CTD
Collab w/ @adaozlemdemir.bsky.social & Aihara, Herzik, & Harris labs
pubs.acs.org/doi/10.1021/...
Collab w/ @adaozlemdemir.bsky.social & Aihara, Herzik, & Harris labs
pubs.acs.org/doi/10.1021/...
March 26, 2025 at 3:21 PM
✨ Check out @mackevinbraza.bsky.social 's new work on full length APOBEC3B, which shows how the NTD modulates active site opening in the CTD
Collab w/ @adaozlemdemir.bsky.social & Aihara, Herzik, & Harris labs
pubs.acs.org/doi/10.1021/...
Collab w/ @adaozlemdemir.bsky.social & Aihara, Herzik, & Harris labs
pubs.acs.org/doi/10.1021/...
Reposted by Lillian Chong
Great collaboration with @ltchong.bsky.social on pathway ensemble clustering. 🌟SHINE🌟 is out in @biorxiv-biophys.bsky.social : www.biorxiv.org/content/10.1..., and of course @lexinc.bsky.social got it in #MDANCE as well: github.com/mqcomplab/MD...
February 10, 2025 at 4:44 PM
Great collaboration with @ltchong.bsky.social on pathway ensemble clustering. 🌟SHINE🌟 is out in @biorxiv-biophys.bsky.social : www.biorxiv.org/content/10.1..., and of course @lexinc.bsky.social got it in #MDANCE as well: github.com/mqcomplab/MD...
Reposted by Lillian Chong
A behemoth effort from @fionachembot.bsky.social in which she does amazing science (showing how VOCs reshape allosteric pathways) while also making the SARS2 spike color palette match her fish Dorry 😍🫠
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
March 13, 2025 at 4:38 AM
A behemoth effort from @fionachembot.bsky.social in which she does amazing science (showing how VOCs reshape allosteric pathways) while also making the SARS2 spike color palette match her fish Dorry 😍🫠
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
@westpasoftware.bsky.social is partnering with @mdanalysis.bsky.social for Google Summer of Code this year. Please help spread the word!
Do you like coding in #Python? Have you been using #MonteCarlo methods or running #MD simulations?
Working with MDAnalysis and @westpasoftware.bsky.social on a GSoC 2025 project may be just for you! For details, read our blog post: www.mdanalysis.org/2025/02/28/g....
Pre-proposal deadline: Mar 21
Working with MDAnalysis and @westpasoftware.bsky.social on a GSoC 2025 project may be just for you! For details, read our blog post: www.mdanalysis.org/2025/02/28/g....
Pre-proposal deadline: Mar 21
March 20, 2025 at 1:34 PM
@westpasoftware.bsky.social is partnering with @mdanalysis.bsky.social for Google Summer of Code this year. Please help spread the word!
Reposted by Lillian Chong
Check out this excellent profile of Catherine Drennan (@drennanlab.bsky.social), Professor of Chemistry and Biology, which was recently published in PNAS:
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
November 14, 2024 at 5:10 PM
Check out this excellent profile of Catherine Drennan (@drennanlab.bsky.social), Professor of Chemistry and Biology, which was recently published in PNAS:
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Lillian Chong
For those following the @prof-ajay-jain.bsky.social /Cleaves/ @wpwalters.bsky.social preprint re: DiffDock @gcorso.bsky.social
I have read some of the back-&-forth between the author groups
As a practitioner in the field for > 20 yrs (academic side), here is my take: 🧵
I have read some of the back-&-forth between the author groups
As a practitioner in the field for > 20 yrs (academic side), here is my take: 🧵
@dereklowe.bsky.social honing in on the same bottom line message from @wpwalters.bsky.social @prof-ajay-jain.bsky.social
it's so true and hits so hard:
it's so true and hits so hard:
December 9, 2024 at 3:46 AM
For those following the @prof-ajay-jain.bsky.social /Cleaves/ @wpwalters.bsky.social preprint re: DiffDock @gcorso.bsky.social
I have read some of the back-&-forth between the author groups
As a practitioner in the field for > 20 yrs (academic side), here is my take: 🧵
I have read some of the back-&-forth between the author groups
As a practitioner in the field for > 20 yrs (academic side), here is my take: 🧵
Reposted by Lillian Chong
pubmed.ncbi.nlm.nih.gov/39643640/ “while AlphaFold3 shows improved performance over AlphaFold2 in predicting overall GPCR backbone architecture, significant discrepancies persist in ligand-binding poses, particularly for ions, peptides, and proteins.”
AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors - PubMed
G protein-coupled receptors (GPCRs) are critical drug targets involved in numerous physiological processes, yet many of their structures remain unresolved due to inherent flexibility and diverse ligan...
pubmed.ncbi.nlm.nih.gov
December 8, 2024 at 2:23 PM
pubmed.ncbi.nlm.nih.gov/39643640/ “while AlphaFold3 shows improved performance over AlphaFold2 in predicting overall GPCR backbone architecture, significant discrepancies persist in ligand-binding poses, particularly for ions, peptides, and proteins.”
Reposted by Lillian Chong
Really fortunate to have had the honor of being featured as part of NVIDIA SC24 special address by Jensen Huang and Ian Buck. This summarizes a lot of the work that is ongoing in the group highlighting the role of LLMs, multi modality and generative AI.
youtu.be/eKzNKxWUeCE
youtu.be/eKzNKxWUeCE
NVIDIA SC24 Special Address
YouTube video by NVIDIA
youtu.be
November 26, 2024 at 5:00 AM
Really fortunate to have had the honor of being featured as part of NVIDIA SC24 special address by Jensen Huang and Ian Buck. This summarizes a lot of the work that is ongoing in the group highlighting the role of LLMs, multi modality and generative AI.
youtu.be/eKzNKxWUeCE
youtu.be/eKzNKxWUeCE
Reposted by Lillian Chong
Check out this bombshell publication by Michael Fischbach @mfgrp.bsky.social and coworkers @stanford-chemh.bsky.social @stanfordmedicine.bsky.social, imagine a cancer immune therapy/vaccine where treatment begins and ends with a painless topical skin treatment! 🤯
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Discovery and engineering of the antibody response to a prominent skin commensal - Nature
Nature - Discovery and engineering of the antibody response to a prominent skin commensal
www.nature.com
December 11, 2024 at 7:26 PM
Check out this bombshell publication by Michael Fischbach @mfgrp.bsky.social and coworkers @stanford-chemh.bsky.social @stanfordmedicine.bsky.social, imagine a cancer immune therapy/vaccine where treatment begins and ends with a painless topical skin treatment! 🤯
www.nature.com/articles/s41...
www.nature.com/articles/s41...