Lang Ding
@loveniannian.bsky.social
Nature reviews molecular cell biology tools of the trade. www.nature.com/articles/s41...
Tissue expansion-enhanced mass-spectrometry imaging decodes biomolecular landscapes - Nature Reviews Molecular Cell Biology
In this Tools of the Trade article, Ding (Wang lab) describes the development of tissue expansion-enhanced mass-spectrometry imaging (TEMI), which combines an optimized tissue expansion method with ma...
www.nature.com
November 17, 2025 at 10:27 PM
Nature reviews molecular cell biology tools of the trade. www.nature.com/articles/s41...
So thrilled to share our tissue-expansion mass-spectrometry imaging (TEMI) paper for high spatially resolved multi-omics mapping!!
Tissue-expansion method compatible with mass-spectrometry imaging (TEMI) enables the profiling of lipids, metabolites, peptides, proteins, and N-glycans in complex tissues with high spatial resolution, advancing spatially resolved multi-omics mapping.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
TEMI: tissue-expansion mass-spectrometry imaging - Nature Methods
Tissue-expansion method compatible with mass-spectrometry imaging (TEMI) enables the profiling of lipids, metabolites, peptides, proteins, and N-glycans in complex tissues with high spatial resolution...
www.nature.com
April 25, 2025 at 12:52 PM
So thrilled to share our tissue-expansion mass-spectrometry imaging (TEMI) paper for high spatially resolved multi-omics mapping!!
Reposted by Lang Ding
🥼A new tissue expansion method developed by researchers in the Wang & Tillberg labs & collaborators @uwmadison.bsky.social enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations ➡️ hhmi.news/4ixHOZZ
New technique expands tissues so hundreds of biomolecules can be seen inside cells
A new tissue expansion method developed by Janelia and University of Wisconsin-Madison researchers enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules
hhmi.news
April 22, 2025 at 2:45 PM
🥼A new tissue expansion method developed by researchers in the Wang & Tillberg labs & collaborators @uwmadison.bsky.social enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations ➡️ hhmi.news/4ixHOZZ
Reposted by Lang Ding
🚨 New: Spleen-resident macrophages (MMMs) can directly activate CD8+ T cells to fight tumors – independently of dendritic cells. They use a vacuolar MHC-I pathway & need Batf3 for this antitumor response.
🧠 A game-changer for immunotherapy?
🔗 www.cell.com/immunity/abs... @cp-immunity.bsky.social
🧠 A game-changer for immunotherapy?
🔗 www.cell.com/immunity/abs... @cp-immunity.bsky.social
March 26, 2025 at 10:12 AM
🚨 New: Spleen-resident macrophages (MMMs) can directly activate CD8+ T cells to fight tumors – independently of dendritic cells. They use a vacuolar MHC-I pathway & need Batf3 for this antitumor response.
🧠 A game-changer for immunotherapy?
🔗 www.cell.com/immunity/abs... @cp-immunity.bsky.social
🧠 A game-changer for immunotherapy?
🔗 www.cell.com/immunity/abs... @cp-immunity.bsky.social
Reposted by Lang Ding
Online now: Online now: A heart-brain-spleen axis controls cardiac remodeling to hypertensive stress
A heart-brain-spleen axis controls cardiac remodeling to hypertensive stress
Hypertensive heart disease, initially established as an adaptive response, might progress toward heart failure, and the nervous and immune systems participate in this process, but their interaction is unclear. Perrotta et al. identify a brain-body circuit…
dlvr.it
March 2, 2025 at 3:48 PM
Online now: Online now: A heart-brain-spleen axis controls cardiac remodeling to hypertensive stress
Reposted by Lang Ding
TEMI: Tissue Expansion Mass Spectrometry Imaging https://www.biorxiv.org/content/10.1101/2025.02.22.639343v1
February 28, 2025 at 2:23 AM
TEMI: Tissue Expansion Mass Spectrometry Imaging https://www.biorxiv.org/content/10.1101/2025.02.22.639343v1
Reposted by Lang Ding
Beyond the leader cell: How pancreatic islets self-organize to control blood sugar.
https://buff.ly/3QpGbSd
https://buff.ly/3QpGbSd
February 17, 2025 at 9:21 AM
Beyond the leader cell: How pancreatic islets self-organize to control blood sugar.
https://buff.ly/3QpGbSd
https://buff.ly/3QpGbSd