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linderlab.bsky.social
LinderLab
@linderlab.bsky.social
35 followers 37 following 21 posts
Macrophages. Podosomes. MMPs. Borreliae.
Not necessarily in that order.
www.linderlab.de
Posts Replies Media Videos
linderlab.bsky.social
A warm welcome to our new PhD student Emma Lautenbach, who will work on the intricacies of the podosome cap 🧢
November 17, 2025 at 12:23 PM
linderlab.bsky.social
A warm welcome to our new lab member Canberk Yesilada, who will be/is already working on his PhD thesis on Borrelia phagocytosis by macrophages 🤗
November 11, 2025 at 2:03 PM
linderlab.bsky.social
Macrophages are super!
SoRA (superresolution after optical reassignment) microscopy video of a primary human macrophage transfected with Lifeact-GFP to visualize actin-rich podosomes.
Star-like appearance is due to connecting cables linking individual podosomes into a cell-wide superstructure ✨
November 7, 2025 at 3:20 PM
linderlab.bsky.social
On our way to Heidelberg to the meeting of the German Society for Cell Biology 🧫
The Linder Lab at Hamburg main station
October 26, 2025 at 7:28 AM
linderlab.bsky.social
New preprint:
Phagocytic podosomes enable efficient uptake of Candida auris by primary human macrophages 🦠👄
www.biorxiv.org/content/10.1...
September 15, 2025 at 1:54 PM
linderlab.bsky.social
Our paper on podosome regulation by myosins 1e/f is now online.
We introduce the concept of the podosome base, a region of plasma membrane-associated components 🔬
Cool collaboration with @renaudpoincloux.bsky.social‬ and Krendel labs
www.sciencedirect.com/science/arti...
September 2, 2025 at 7:48 AM
linderlab.bsky.social
Congratulations to our lab member Bryan Barcelona to a super fancy defense on software-based analysis of cell and podosome parameters 👨‍🎓
August 26, 2025 at 7:07 AM
linderlab.bsky.social
Cellular fireworks
(in a primary human macrophage):
Microtubule +tips, labeled by CLIP170-GFP, move from the microtubule organizing center (MTOC) to the cell periphery ✨
July 9, 2025 at 7:59 AM
Reposted by LinderLab
pjsaez.bsky.social
This is why we love #cellmigration

#Leukocytes: #Neutrophils (cyan) #Macrophages (orange) chemotaxis.

I couldn't share it before the retirement of @zebrafishrock.bsky.social, but cool #microscopy in #zebrafish continue to rock !

#scicomm #scisky @cellcommlab.bsky.social @focalplane.bsky.social 🧪🔬
July 8, 2025 at 10:18 AM
linderlab.bsky.social
A warm welcome to our new master student Mahmood Tarmom, who will work on podosome proteins of (yet) unknown function 🔬
July 4, 2025 at 1:15 PM
linderlab.bsky.social
Coming up: "Live Biological Imaging Across Scales", part of the Royal Microscopic Society line of Wiley books.
Featuring 10 chapters from international experts on live imaging from molecules to organisms.
Edited by Claire M. Wells and yours truly 📘🧬🐭
June 23, 2025 at 8:20 AM
linderlab.bsky.social
Our preprint on podosome regulation by unconventional myosins in now on BioRxiv. Great collaboration with the @renaudpoincloux.bsky.social and Krendel labs.
www.biorxiv.org/content/10.1...

We introduce the concept of the "podosome base", a region of plasma membrane-associated podosome components.
Myo1e (green) shows a more ventral localization than the F-actin core (red) of podosomes. XZ side view of two podosomes.
April 30, 2025 at 8:14 AM
Reposted by LinderLab
tomgauld.bsky.social
My latest @newscientist.com cartoon
Title: SOME GRAMMATICAL VOICES FOR USE IN SCIENTIFIC WRITING ACTIVE VOICE e.g. Our team collected samples and then we tested them. CLICKBAIT VOICE e.g. We collected some samples... You won't believe what happened next! PASSIVE VOICE e.g. Samples were collected and tested. HAIKU VOICE e.g. Quiet science lab. Workers arrive with samples. The testing begins. PASSIVE-AGGRESSIVE VOICE e.g. We did all the collecting and testing. No need to thank us. Just doing our job. CONSPIRACY VOICE e.g. Mysterious "Samples" were harvested and covertly "tested" by so-called scientists.
April 28, 2025 at 10:09 AM
Reposted by LinderLab
itzenlab.bsky.social
Interesting preprint from the Windhorst, Marlovits and Linder (@linderlab.bsky.social) groups: They investigate the spectrum of actin binding motives that may exist in many proteins.
www.biorxiv.org/content/10.1...
Discovery of a new evolutionarily conserved short linear F-actin binding motif
Regulation of the actin cytoskeleton by actin binding proteins (ABPs) is essential for cellular homeostasis, and the mode of actin binding determines the activity of ABPs. Here, we discovered a novel ...
www.biorxiv.org
April 24, 2025 at 8:29 AM
linderlab.bsky.social
Interested in cutting edge Microscopy Techniques?
Check out the latest special issue of Journal of Microscopy, edited by yours truly 🔬
onlinelibrary.wiley.com/toc/13652818...
Special Issue: Microscopy Techniques: Journal of Microscopy: Vol 298, No 2
The <em>Journal of Microscopy</em> is the oldest journal dedicated to the science of microscopy, publishing the latest advances in microscopy techniques and novel areas of application.
onlinelibrary.wiley.com
April 14, 2025 at 8:11 AM
Reposted by LinderLab
rtg2771.bsky.social
🧑‍🎓👩‍🎓We are hiring:

PhD student positions in Molecular Infection Biology
in DFG Research Training Group Humans and Microbes
@cssbhamburg.bsky.social @leibnizliv.bsky.social @bosse-lab.bsky.social @linderlab.bsky.social @itzenlab.bsky.social #UKE #UHH #BNITM

📬Apply until June 20, 2025.
grk2771.de
April 11, 2025 at 11:56 AM
linderlab.bsky.social
Upcoming meeting:
11th Trippenhuis meeting of the Dutch Society for Cell Biology
(Amsterdam, May 8-9) 🏠
April 9, 2025 at 10:29 AM
linderlab.bsky.social
We are hiring!
The DFG-funded RTG2771 training group is offering PhD positions in molecular infection biology for 3-4 years
For more information, see grk2771.de
(our lab is project 4) 👨‍🎓
RTG 2771 – Humans and Microbes – Reorganization of Cell Compartments and Molecular Interactions during Infection
grk2771.de
April 8, 2025 at 11:19 AM
linderlab.bsky.social
Farewell sushi dinner for our longtime assistant Andrea who is now retiring 🥲🍣
April 1, 2025 at 7:57 AM
linderlab.bsky.social
Congratulations to our lab member Rawan Batlouni for an excellent MD thesis on phagocytic podosomes 👨‍🎓
March 10, 2025 at 8:44 AM
linderlab.bsky.social
A warm welcome to our new MD student Fan Yang, who will work on Borrelia-macrophage interaction 🤗
February 26, 2025 at 10:44 AM
linderlab.bsky.social
Video of a FIB-SEM analysed macrophage phagosome containing a single Borrelia cell being compacted by membrane tubulation, leading to reduction of the phagosome volume.
Phagosome membrane in blue, Borrelia in turquoise. Watch for start of transparency mid-video 🪱
pubmed.ncbi.nlm.nih.gov/33380490/
February 21, 2025 at 12:26 PM
Reposted by LinderLab
rtg2771.bsky.social
Registration and abstract submission for our International Symposium Cell and Structural Biology of Host Pathogen Interaction from 10 – 12 Sept 2025 @cssbhamburg.bsky.social in Hamburg, Germany are now open.

✅ Register here: express.converia.de/frontend/ind...
💡More info: humansandmicrobes2025.de
Humans and Microbes 2025 – Symposium Cell and Structural Biology of Host Pathogen Interaction
humansandmicrobes2025.de
February 3, 2025 at 8:43 PM
Reposted by LinderLab
rtg2771.bsky.social
🚨 Save the date! 🚨
We're thrilled to announce our International Symposium on Cell & Structural Biology of Host-Pathogen Interaction
📅 Sept 10-12, 2025
📍
@cssbhamburg.bsky.social Hamburg

Registration starts soon
For more info:
humansandmicrobes2025.de
January 29, 2025 at 1:21 PM
linderlab.bsky.social
New account, new publication:
Our video article on building your own tumor spheroid-macrophage coinvasion assay is now online 🎤
review.jove.com/de/t/67374/a...
A Macrophage-Tumor Spheroid Co-Invasion Assay | Protocol
Scientific Article | Here, we present a protocol to investigate the interaction of primary human monocyte-derived macrophages with a tumor spheroid in a...
review.jove.com
January 30, 2025 at 10:23 AM