LinderLab
@linderlab.bsky.social
Macrophages. Podosomes. MMPs. Borreliae.
Not necessarily in that order.
www.linderlab.de
Not necessarily in that order.
www.linderlab.de
Macrophages are super!
SoRA (superresolution after optical reassignment) microscopy video of a primary human macrophage transfected with Lifeact-GFP to visualize actin-rich podosomes.
Star-like appearance is due to connecting cables linking individual podosomes into a cell-wide superstructure ✨
SoRA (superresolution after optical reassignment) microscopy video of a primary human macrophage transfected with Lifeact-GFP to visualize actin-rich podosomes.
Star-like appearance is due to connecting cables linking individual podosomes into a cell-wide superstructure ✨
November 7, 2025 at 3:20 PM
Macrophages are super!
SoRA (superresolution after optical reassignment) microscopy video of a primary human macrophage transfected with Lifeact-GFP to visualize actin-rich podosomes.
Star-like appearance is due to connecting cables linking individual podosomes into a cell-wide superstructure ✨
SoRA (superresolution after optical reassignment) microscopy video of a primary human macrophage transfected with Lifeact-GFP to visualize actin-rich podosomes.
Star-like appearance is due to connecting cables linking individual podosomes into a cell-wide superstructure ✨
New preprint:
Phagocytic podosomes enable efficient uptake of Candida auris by primary human macrophages 🦠👄
www.biorxiv.org/content/10.1...
Phagocytic podosomes enable efficient uptake of Candida auris by primary human macrophages 🦠👄
www.biorxiv.org/content/10.1...
September 15, 2025 at 1:54 PM
New preprint:
Phagocytic podosomes enable efficient uptake of Candida auris by primary human macrophages 🦠👄
www.biorxiv.org/content/10.1...
Phagocytic podosomes enable efficient uptake of Candida auris by primary human macrophages 🦠👄
www.biorxiv.org/content/10.1...
Cellular fireworks
(in a primary human macrophage):
Microtubule +tips, labeled by CLIP170-GFP, move from the microtubule organizing center (MTOC) to the cell periphery ✨
(in a primary human macrophage):
Microtubule +tips, labeled by CLIP170-GFP, move from the microtubule organizing center (MTOC) to the cell periphery ✨
July 9, 2025 at 7:59 AM
Cellular fireworks
(in a primary human macrophage):
Microtubule +tips, labeled by CLIP170-GFP, move from the microtubule organizing center (MTOC) to the cell periphery ✨
(in a primary human macrophage):
Microtubule +tips, labeled by CLIP170-GFP, move from the microtubule organizing center (MTOC) to the cell periphery ✨
Video of a FIB-SEM analysed macrophage phagosome containing a single Borrelia cell being compacted by membrane tubulation, leading to reduction of the phagosome volume.
Phagosome membrane in blue, Borrelia in turquoise. Watch for start of transparency mid-video 🪱
pubmed.ncbi.nlm.nih.gov/33380490/
Phagosome membrane in blue, Borrelia in turquoise. Watch for start of transparency mid-video 🪱
pubmed.ncbi.nlm.nih.gov/33380490/
February 21, 2025 at 12:26 PM
Video of a FIB-SEM analysed macrophage phagosome containing a single Borrelia cell being compacted by membrane tubulation, leading to reduction of the phagosome volume.
Phagosome membrane in blue, Borrelia in turquoise. Watch for start of transparency mid-video 🪱
pubmed.ncbi.nlm.nih.gov/33380490/
Phagosome membrane in blue, Borrelia in turquoise. Watch for start of transparency mid-video 🪱
pubmed.ncbi.nlm.nih.gov/33380490/