Wilhelm Lab
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labwilhelm.bsky.social
Wilhelm Lab
@labwilhelm.bsky.social
Research group studying metabolic and dietary control of mucosal immunology - led by Dr. Christoph Wilhelm at the University of Bonn
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Ever wondered how fasting is benefiting the adaptive immune response? In @Nature we show that #ketogenesis promotes the function of #tcell in severe respiratory viral infections by providing #ketonebodies BHB as carbon source. Final edited version: www.nature.com/articles/s41...
Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19 - Nature
The ketone body β-hydroxybutyrate can be used as an alternative carbon source by T cells to maintain their function during severe respiratory viral infections, including infection with&...
www.nature.com
Reposted by Wilhelm Lab
Hurray! ImmunoSensation will go on! 🥳
The @dfg.de just announced that ImmunoSensation3, focussing on Immune Diversity will be funded!
Let us #celebrate 7 more years of #immunology in #Bonn 🎉

www.immunosensation.de/news/immunos...
Excellence Strategy Funds Bonn Cluster for Immune Research
The Bonn Cluster of Excellence ImmunoSensation will be funded for a further seven years as part of the Excellence Strategy of the German federal and state…
www.immunosensation.de
May 22, 2025 at 3:55 PM
Congratulations Christoph an collegues!! 🎉🥳🥳🎊https://www.nature.com/articles/s41590-025-02104-y
Tuft cell IL-17RB restrains IL-25 bioavailability and reveals context-dependent ILC2 hypoproliferation - Nature Immunology
Tuft cells constitutively express IL-25 to sustain ILC2 homeostasis in the intestine, but mechanisms driving IL-25 secretion have been unclear. Here, Feng et al. find that tuft cells express IL-17RB, ...
www.nature.com
March 13, 2025 at 4:14 PM
Alaaf!!!
February 27, 2025 at 12:19 PM
Reposted by Wilhelm Lab
whoever speaks german, please read this article by constantin seibt from the @republik.ch (unfortunately there is no english translation yet)

www.republik.ch/2025/02/07/d...
Die goldene Zeit des Donald Trump
Der neue US-Präsident zerstört Institutionen, Wissenschaft, die eigene Zukunft.
www.republik.ch
February 7, 2025 at 5:28 PM
Very important information to understand what is currently going on in the US. Please share and distribute www.science.org/content/blog...
Revised and Extended: What's Happening Inside the NIH and NSF
www.science.org
February 7, 2025 at 10:26 AM
Reposted by Wilhelm Lab
Kicking off the 2nd funding period of our SFB1454 on #metaflammation ! Lots of great discussions and visiting our #healthybition at the #museumkoenig in Bonn! Go and visit the exhibition until end of October 2025!
January 30, 2025 at 8:27 PM
Reposted by Wilhelm Lab
🚨 Open #position! The group of Christoph Wilhelm at the University Hospital Bonn is looking for a

Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity

Application deadline is February 10!

Visit our website for more information.

#job #postdoc #science #immunology
January 15, 2025 at 6:54 AM
We are hiring! 📣Interested in how host metabolism, diets, #fasting and #ketogenesis affect the immune response? 👇We are offering a #postdoc position to work on the interplay of host metabolism and immunity. Apply by email or DM directly.
January 16, 2025 at 3:48 PM
Reposted by Wilhelm Lab
Hypoxia-inducible factor 2α promotes protective Th2 cell responses during intestinal helminth infection https://www.biorxiv.org/content/10.1101/2025.01.09.631414v1
January 14, 2025 at 6:15 PM
Reposted by Wilhelm Lab
What defines the #WesternLifestyle and how does it impact our health and the planet? 🌍
“What the Health – Eine Welt. Deine Gesundheit!” explores these connections!
Visit our #healthybition and the accompanying program
📍 @museumkoenig until 26.10.2025
#unibonn #metaflammation #unistiftung
December 11, 2024 at 7:33 AM
Reposted by Wilhelm Lab
My inaugural post on Bluesky - quite fittingly, I'm thrilled to share our first study on heat acclimation, which identifies a neuronal mechanism that drives heat tolerance in mice. (www.nature.com/articles/s41... )
Here is the gist 🧵 (1/n):
Thermally induced neuronal plasticity in the hypothalamus mediates heat tolerance - Nature Neuroscience
Ambroziak, Nencini, Pohle and colleagues identify a slowly emerging plasticity mechanism in a discrete set of hypothalamic preoptic neurons that is triggered by long-term heat exposure and that drives...
www.nature.com
December 10, 2024 at 9:59 PM
Really glad we pulled this of together! @wachtenlab.bsky.social, Andreas Schlitzer and all PIs from #Metaflammation
After the celebrations of making it into the second funding period, we are now ready for a fresh start in this community - stay tuned for more information about #metaflammation #obesity from our @sfb1454.bsky.social funded by the @dfgpublic.bsky.social
www.sfb1454-metaflammation.de
December 5, 2024 at 1:04 PM
Thanks so much DFG for funding our CRC #1454 #Metaflammtion for another 4 years. Looking forward to unravel the immune mechanisms underlying #obesity and #diabetes together with an excellent team of scientists.
www.dfg.de/de/service/p...

www.sfb1454-metaflammation.de/sfb-1454/news
DFG fördert sieben neue Sonderforschungsbereiche
www.dfg.de
November 25, 2024 at 12:36 PM
Reposted by Wilhelm Lab
many new members, many still to join #neuroscience #immunology
go.bsky.app/Eaua5Jk my starter for neuroimmunology
November 20, 2024 at 5:29 AM
Ever wondered how fasting is benefiting the adaptive immune response? In @Nature we show that #ketogenesis promotes the function of #tcell in severe respiratory viral infections by providing #ketonebodies BHB as carbon source. Final edited version: www.nature.com/articles/s41...
Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19 - Nature
The ketone body β-hydroxybutyrate can be used as an alternative carbon source by T cells to maintain their function during severe respiratory viral infections, including infection with&...
www.nature.com
November 19, 2024 at 11:33 AM