kmechtler.bsky.social
@kmechtler.bsky.social
It is an honor to inform you that our manuscript with low resolution FAIMS is now online

www.biorxiv.org/content/10.1...
Low-resolution FAIMS for increased peptide coverage in low-load and single-cell proteomics
Field Asymmetric Ion Mobility Spectrometry (FAIMS) enhances signal to noise ratio filtering ions based on their differential mobility, making it an indispensable tool for single-cell and low-input pro...
www.biorxiv.org
August 28, 2025 at 1:01 PM
Reposted
We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social.
www.science.org/doi/10.1126/...
🧵
Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics
Single-cell transcriptomics (scRNA-seq) has facilitated the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, the exclusive use of mRNA measurem...
www.science.org
August 22, 2025 at 6:03 AM
Reposted
Start of day 2 of the European Symposium on Single Cell Proteomics with @ryankellybyu.bsky.social telling us about high throughput proteomics towards a $10 proteome #ESCP2025
August 27, 2025 at 7:22 AM
Reposted
Mikaela now tells us about the scverse community intrageted ecosystem for single cell with established templates and data structures #ESCP2025
August 27, 2025 at 7:47 AM
Reposted
Wilfred Rossol is next talking about proteomic profiling of protein aggregates with a more spatial proteomics approach #ESCP2025
August 26, 2025 at 1:18 PM
Reposted
Its exciting to see that its a full house at #ESCP2025 lots of enthusiastic single cell proteomics researchers 🤓
August 26, 2025 at 1:26 PM
Reposted
The last session of the day is opened by Tami Geiger looking at the interactions of the immune cells with the cancer microenvironments using single cell proteomics #ESCP2025
August 26, 2025 at 3:02 PM
Reposted
Alexander Ivanov talking about increases in sensitivity and signal to noise when changing to ultra low flor rates for single cell proteomics. #ESCP2025
August 26, 2025 at 3:43 PM
Reposted
Seriously pumped for today! Deep Visual Proteomics masterclass here we come 🤓
August 25, 2025 at 7:07 AM
Reposted
Great from from @erwinschoof.bsky.social and his lab showing the added value of SCP!
Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics www.science.org/doi/...

---
#proteomics #prot-paper
August 25, 2025 at 10:36 AM
Reposted
On my way to ESCP. Super looking forward to this awesome meeting!
The European Symposium on Single Cell Proteomics (ESCP) will be held in Vienna for the 6th time, from August 26th – 27th 2025 This year's focus will include spatial proteomics studies on the single-cell level. There is no registration fee
Hotel rooms in Vienna are inexpensive.
www.apma.at/6thescp/
6th ESCP 2025 – APMA
www.apma.at
August 25, 2025 at 12:59 PM
Reposted
Only a few more hours! 😃
The European Symposium on Single Cell Proteomics (ESCP) will be held in Vienna for the 6th time, from August 26th – 27th 2025 This year's focus will include spatial proteomics studies on the single-cell level. There is no registration fee
Hotel rooms in Vienna are inexpensive.
www.apma.at/6thescp/
6th ESCP 2025 – APMA
www.apma.at
August 26, 2025 at 4:19 AM
Reposted
Start of the European symposium in single cell proteomics at beautiful Viena with a workshop on spatial proteomics organised by @coscialab.bsky.social
August 25, 2025 at 7:08 AM
Reposted
After the DVP symposium now begins the start of the European Symposium on Single Cell Proteomics #ECSP25

A quick intro from @kmechtler.bsky.social and we kick off two days of exciting science starting with SCP of neutrophils in glioblastoma
August 26, 2025 at 6:59 AM
Reposted
Next up is @vadim-demichev.bsky.social telling us how quantitatively accurate is single cell proteomics

#ESCP2025
August 26, 2025 at 8:19 AM
Reposted
Cool work from @nanopots.bsky.social doing cell surface profiling of 100-500 immine cells using affinity purification #ESCP2025
August 26, 2025 at 10:14 AM
Reposted
Daniela Valdes from @coscialab.bsky.social lab presents how smoking disrupts the placental function via macrophage dysregulation using single nuclei analysis and deep visual proteomics #ESCP2025
August 26, 2025 at 10:59 AM
Reposted
After a long trek from Melbourne, Jarrod is now on the ground in Vienna and enjoying #ESCP2025 - together with Joris, our new Business Development Manager for Europe.

Stop by the IonOpticks stand and chat with Jarrod and Joris about how our new product releases can support your single-cell work.
August 26, 2025 at 12:11 PM
Reposted
Up next is @jwoessmann.bsky.social from the @erwinschoof.bsky.social lab showing how to focus on the exciting lower abundance proteins with single cell proteomics #ESCP2025
August 26, 2025 at 12:22 PM
Reposted
Next up is @pedroaragon.bsky.social talking about single cell and low input proteomics to study perturbation in leukemia #ESCP2025
August 26, 2025 at 12:47 PM
Reposted
Thanks to all who helped make this possible: the EMERGE team, research nurses, clinical & research collaborators & patients.

@kmechtler.bsky.social
@pranvera.bsky.social
@patriciacoelho.bsky.social
@ajmhowden.bsky.social
@mas-g.bsky.social
@walmsley-lab.bsky.social
@edinuni-irr.bsky.social
July 27, 2025 at 1:39 PM
#ESCP25: The first scientific abstracts have been submitted, and I can only say one thing—it's going to be incredibly exciting.

Enclosed can you find one of our highlights presented by Ying:
"Affinity purification mass spectrometry: the next frontier of single-cell and low-input proteomics".
July 17, 2025 at 11:01 AM
Breaking ESCP25 news:

Ahead of the ESCP conference we will offer a Deep Visual Proteomics (DVP) workshop on August 25th 2025.
Participation is free of charge, but registration is required! (www.apma.at/6thescp)
Enclosed can you find the preliminary program:
July 17, 2025 at 10:45 AM
I would like to inform you that the registration deadline for our ESCP25 conference is July 27th.
We are looking forward to interesting scientific contributions.
July 10, 2025 at 8:39 PM
The European Symposium on Single Cell Proteomics (ESCP) will be held in Vienna for the 6th time, from August 26th – 27th 2025 This year's focus will include spatial proteomics studies on the single-cell level. There is no registration fee
Hotel rooms in Vienna are inexpensive.
www.apma.at/6thescp/
6th ESCP 2025 – APMA
www.apma.at
June 27, 2025 at 1:04 PM