Kari Wisinski, MD
@kariwisinskimd.bsky.social
Breast Med Onc & Chief of Heme/Onc/Pall Care, UW Medicine & Carbone Cancer Center. Mom of 3. Enjoys travel, books, volleyball. Thoughts shared are my own and not my employer.
Pinned
future.how - future Resources and Information.
future.how is your first and best source for all of the information you’re looking for. From general topics to more of what you would expect to find here, future.how has it all. We hope you find what ...
future.how
Key take homes for #breastcancer at #ASCO25 (3)
*Triplet PI3k (Inavo)+fulv+palbo improved OS in MBC in those with early progression on adjuvant AI (need early NGS for PIK3CA
*TDXd (plus pertuz) improves PFS in 1L HER2+ MBC. Will watch for PFS2/OS in future. Key ? is how to integrate PATINA in ER+
*Triplet PI3k (Inavo)+fulv+palbo improved OS in MBC in those with early progression on adjuvant AI (need early NGS for PIK3CA
*TDXd (plus pertuz) improves PFS in 1L HER2+ MBC. Will watch for PFS2/OS in future. Key ? is how to integrate PATINA in ER+
Great @bigtencrc.bsky.social summit today. Advancing cancer research collaboration across the growing BigTen (now 18!) team. Honoring colleagues including Dr. Bailey and meeting new members.
September 13, 2025 at 12:43 AM
Great @bigtencrc.bsky.social summit today. Advancing cancer research collaboration across the growing BigTen (now 18!) team. Honoring colleagues including Dr. Bailey and meeting new members.
Excited by this new opportunity at the Carbone Cancer Center @uwhealth.bsky.social and know Dr. Uboha will be an excellent leader of our clinical trials program! www.linkedin.com/feed/update/...
We are delighted to announce two key leadership promotions, elevating staff who have played an integral role in strengthening clinical research and innovating new patient care across cancer… | UW Carb...
We are delighted to announce two key leadership promotions, elevating staff who have played an integral role in strengthening clinical research and innovating new patient care across cancer types.
K...
www.linkedin.com
September 6, 2025 at 8:13 PM
Excited by this new opportunity at the Carbone Cancer Center @uwhealth.bsky.social and know Dr. Uboha will be an excellent leader of our clinical trials program! www.linkedin.com/feed/update/...
Look at Darian, research coordinator @uw Carbone presenting this trial
A Big Ten CRC study, BTCRC-BRE19-409, was presented at #AACR25 by Darian Louthan at UW Carbone Cancer Center.
Congratulations to all co-authors and study teams whose hard work led to this publication!
Read more: bigtencrc.org/btcrc-bre19-...
Congratulations to all co-authors and study teams whose hard work led to this publication!
Read more: bigtencrc.org/btcrc-bre19-...
July 19, 2025 at 1:20 AM
Look at Darian, research coordinator @uw Carbone presenting this trial
Excited to see this BigTen met TNBC study @bigtenplus.bsky.social published. Although primary endpt not met, addressed an important question and some interesting observations for future. link.springer.com/article/10.1...
Phase I/II trial investigating gedatolisib plus talazoparib in advanced triple negative or BRCA1/2 positive, HER2 negative breast cancers - Breast Cancer Research and Treatment
Purpose Metastatic triple negative breast cancer has a poor prognosis with limited targeted treatment options. In preclinical studies PI3K inhibition led to increased DNA damage and subsequent sensiti...
link.springer.com
June 5, 2025 at 1:32 PM
Excited to see this BigTen met TNBC study @bigtenplus.bsky.social published. Although primary endpt not met, addressed an important question and some interesting observations for future. link.springer.com/article/10.1...
Reposted by Kari Wisinski, MD
In women with node-positive breast cancer whose nodes became free of disease after neoadjuvant therapy, regional nodal irradiation did not reduce breast cancer recurrence or improve survival. Full results from a phase 3 trial: nej.md/4dM6LjD
#MedSky #Oncology
#MedSky #Oncology
Omitting Regional Nodal Irradiation after Response to Neoadjuvant Chemotherapy | NEJM
The benefit of regional nodal irradiation in the treatment of breast cancer is well established for patients with pathologically positive axillary nodes, but whether it is also beneficial for patie...
nej.md
June 4, 2025 at 10:03 PM
In women with node-positive breast cancer whose nodes became free of disease after neoadjuvant therapy, regional nodal irradiation did not reduce breast cancer recurrence or improve survival. Full results from a phase 3 trial: nej.md/4dM6LjD
#MedSky #Oncology
#MedSky #Oncology
Key take homes for #breastcancer at #ASCO25 (3)
*Triplet PI3k (Inavo)+fulv+palbo improved OS in MBC in those with early progression on adjuvant AI (need early NGS for PIK3CA
*TDXd (plus pertuz) improves PFS in 1L HER2+ MBC. Will watch for PFS2/OS in future. Key ? is how to integrate PATINA in ER+
*Triplet PI3k (Inavo)+fulv+palbo improved OS in MBC in those with early progression on adjuvant AI (need early NGS for PIK3CA
*TDXd (plus pertuz) improves PFS in 1L HER2+ MBC. Will watch for PFS2/OS in future. Key ? is how to integrate PATINA in ER+
future.how - future Resources and Information.
future.how is your first and best source for all of the information you’re looking for. From general topics to more of what you would expect to find here, future.how has it all. We hope you find what ...
future.how
June 4, 2025 at 1:48 AM
Key take homes for #breastcancer at #ASCO25 (3)
*Triplet PI3k (Inavo)+fulv+palbo improved OS in MBC in those with early progression on adjuvant AI (need early NGS for PIK3CA
*TDXd (plus pertuz) improves PFS in 1L HER2+ MBC. Will watch for PFS2/OS in future. Key ? is how to integrate PATINA in ER+
*Triplet PI3k (Inavo)+fulv+palbo improved OS in MBC in those with early progression on adjuvant AI (need early NGS for PIK3CA
*TDXd (plus pertuz) improves PFS in 1L HER2+ MBC. Will watch for PFS2/OS in future. Key ? is how to integrate PATINA in ER+
Key take homes for #breastcancer at #ASCO25 (2)
*1st PROTAC (vepdeg) improves PFS in mESR1 MBC
*Monitoring ctDNA for ESR1 mutations in MBC w early change to SERD (cami) improves PFS, longer term outcomes important
*Dose escalation of abema improves tolerance (TRADE)
*1st PROTAC (vepdeg) improves PFS in mESR1 MBC
*Monitoring ctDNA for ESR1 mutations in MBC w early change to SERD (cami) improves PFS, longer term outcomes important
*Dose escalation of abema improves tolerance (TRADE)
June 4, 2025 at 1:40 AM
Key take homes for #breastcancer at #ASCO25 (2)
*1st PROTAC (vepdeg) improves PFS in mESR1 MBC
*Monitoring ctDNA for ESR1 mutations in MBC w early change to SERD (cami) improves PFS, longer term outcomes important
*Dose escalation of abema improves tolerance (TRADE)
*1st PROTAC (vepdeg) improves PFS in mESR1 MBC
*Monitoring ctDNA for ESR1 mutations in MBC w early change to SERD (cami) improves PFS, longer term outcomes important
*Dose escalation of abema improves tolerance (TRADE)
Key take homes for #breastcancer at #ASCO25 (1)
*OFS/AI in high risk preM women reduced recurrence. OS not met (at 15 yrs) but w/o detriment to non-cancer OS
*Vasomotor AEs from ET effectively reduced w elinzanetant
*Select stage 1-3 HER2+ BC may not need carbo
*SG + pembro is a new 1L TNBC option
*OFS/AI in high risk preM women reduced recurrence. OS not met (at 15 yrs) but w/o detriment to non-cancer OS
*Vasomotor AEs from ET effectively reduced w elinzanetant
*Select stage 1-3 HER2+ BC may not need carbo
*SG + pembro is a new 1L TNBC option
June 4, 2025 at 1:32 AM
Key take homes for #breastcancer at #ASCO25 (1)
*OFS/AI in high risk preM women reduced recurrence. OS not met (at 15 yrs) but w/o detriment to non-cancer OS
*Vasomotor AEs from ET effectively reduced w elinzanetant
*Select stage 1-3 HER2+ BC may not need carbo
*SG + pembro is a new 1L TNBC option
*OFS/AI in high risk preM women reduced recurrence. OS not met (at 15 yrs) but w/o detriment to non-cancer OS
*Vasomotor AEs from ET effectively reduced w elinzanetant
*Select stage 1-3 HER2+ BC may not need carbo
*SG + pembro is a new 1L TNBC option
What a great surprise from the breast med onc clinic team today! Made my day-so thoughtful.
June 4, 2025 at 1:18 AM
What a great surprise from the breast med onc clinic team today! Made my day-so thoughtful.
Reposted by Kari Wisinski, MD
Meet Mahua Dey — neurosurgeon, scientist and innovator at @uwmadison.bsky.social. She's leading the charge against glioblastoma, one of the deadliest brain cancers. Her lab's personalized therapeutic vaccine, GIFT-7, has shown remarkable success in preclinical trials.
Pursuing a vaccine to treat glioblastoma - School of Medicine and Public Health
Dr. Mahua Dey is an associate professor in the Department of Neurological Surgery and the director of the surgical neuro-oncology program in the University of Wisconsin School of Medicine and Public Health. She specializes in the surgical management of both benign and malignant brain tumors.
www.med.wisc.edu
May 21, 2025 at 11:55 PM
Meet Mahua Dey — neurosurgeon, scientist and innovator at @uwmadison.bsky.social. She's leading the charge against glioblastoma, one of the deadliest brain cancers. Her lab's personalized therapeutic vaccine, GIFT-7, has shown remarkable success in preclinical trials.
Former Univ of Wisconsin heme/onc fellow!!
We’re off to a strong start at @binaytara.bsky.social Nebraska Congress in Omaha! Dr. Chris D’Angelo of@nebraskamed.bsky.social kicked things off with an engaging opening.
Great energy as experts dive into advances in blood cancer care.
#Binaytara #Hematology #BloodCancer #CME #MedicalEducation
Great energy as experts dive into advances in blood cancer care.
#Binaytara #Hematology #BloodCancer #CME #MedicalEducation
April 13, 2025 at 1:12 PM
Former Univ of Wisconsin heme/onc fellow!!
Just talked about these results with 2 pts in 2 weeks. Improved outcomes with ET in ERlow breast cancer, unless pCR to Neoadj chemo. ascopubs.org/doi/10.1200/...
Endocrine Therapy Omission in Estrogen Receptor–Low (1%-10%) Early-Stage Breast Cancer
PURPOSEAdjuvant endocrine therapy (ET) improves overall survival (OS) in estrogen receptor
(ER)–positive early-stage breast cancer (BC). However, the benefit of ET for those
with ER-low BC (ER 1%-10%)...
ascopubs.org
April 13, 2025 at 12:55 PM
Just talked about these results with 2 pts in 2 weeks. Improved outcomes with ET in ERlow breast cancer, unless pCR to Neoadj chemo. ascopubs.org/doi/10.1200/...
Reposted by Kari Wisinski, MD
NIH layoffs delay research benefiting cancer patients, and celebrity cancer news is often missing important information, and more news from Cancer Today magazine: www.cancertodaymag.org/cancer-talk/...
April 11: The Week in Cancer News | Cancer Today
NIH layoffs delay research benefiting cancer patients, and celebrity cancer news is often missing important information.
www.cancertodaymag.org
April 11, 2025 at 6:20 PM
NIH layoffs delay research benefiting cancer patients, and celebrity cancer news is often missing important information, and more news from Cancer Today magazine: www.cancertodaymag.org/cancer-talk/...
Loving the @uwhealth.bsky.social Carbone Cancer Center Community day for @uwbadgers.bsky.social science days. Attempted Brain surgery (sticking to med onc), attended panel on working w research advocates, ice cream and more!
April 6, 2025 at 6:47 PM
Loving the @uwhealth.bsky.social Carbone Cancer Center Community day for @uwbadgers.bsky.social science days. Attempted Brain surgery (sticking to med onc), attended panel on working w research advocates, ice cream and more!
Reposted by Kari Wisinski, MD
Working with an interdisciplinary team, we have developed a website to communicate how the White House's proposed cuts to health research would cause losses of $16B and 68,500 jobs.
Find out how your community may be impacted.
Explore more at SCIMaP: scienceimpacts.org
a 🧵
Find out how your community may be impacted.
Explore more at SCIMaP: scienceimpacts.org
a 🧵
March 28, 2025 at 2:15 AM
Working with an interdisciplinary team, we have developed a website to communicate how the White House's proposed cuts to health research would cause losses of $16B and 68,500 jobs.
Find out how your community may be impacted.
Explore more at SCIMaP: scienceimpacts.org
a 🧵
Find out how your community may be impacted.
Explore more at SCIMaP: scienceimpacts.org
a 🧵
The resignation letter should be seen by all. A reminder to keep speaking up/advocating for science.
A top vaccine advisor at the FDA was forced to resign on Friday. In his resignation letter, Dr. Peter Marks, wrote "truth and transparency are not desired," by HHS Secretary Robert F. Kennedy Jr.
The top FDA vaccine official is forced out, cites RFK Jr.'s 'misinformation and lies'
A top vaccine advisor at the FDA was forced to resign on Friday. In his resignation letter, Dr. Peter Marks wrote "truth and transparency are not desired," by HHS Secretary Robert F. Kennedy Jr.
www.npr.org
March 29, 2025 at 3:10 PM
The resignation letter should be seen by all. A reminder to keep speaking up/advocating for science.
Reposted by Kari Wisinski, MD
Peter Marks forced to resign www.bbc.co.uk/news/article...
Peter Marks, top US vaccine official, forced to resign, reports say
In his resignation letter, Peter Marks said his new boss, Robert F Kennedy Jr, favoured
www.bbc.co.uk
March 29, 2025 at 3:02 PM
Peter Marks forced to resign www.bbc.co.uk/news/article...
Had a great team dinner with these amazing @uwhealth.bsky.social breast nurses, MAs, pharmacists, APPs and oncologists last night! Fills the cup. @marina-sharifi.bsky.social
March 21, 2025 at 1:28 PM
Had a great team dinner with these amazing @uwhealth.bsky.social breast nurses, MAs, pharmacists, APPs and oncologists last night! Fills the cup. @marina-sharifi.bsky.social
What a great day at our 2025 retreat- celebrating and socializing with colleagues and planning for the upcoming year. @marina-sharifi.bsky.social @noelleloconte.bsky.social @joshlangmd.bsky.social
March 8, 2025 at 12:25 AM
What a great day at our 2025 retreat- celebrating and socializing with colleagues and planning for the upcoming year. @marina-sharifi.bsky.social @noelleloconte.bsky.social @joshlangmd.bsky.social
Reposted by Kari Wisinski, MD
Now online in Cancer Discovery: High-Purity Circulating Tumor Cell RNA Sequencing Identifies #ProstateCancer Lineage Phenotypes Prognostic for Clinical Outcomes - by Marina Sharifi, Jamie Sperger, Shuang Zhao, Joshua Lang, and colleagues doi.org/10.1158/2159...
February 6, 2025 at 4:42 PM
Now online in Cancer Discovery: High-Purity Circulating Tumor Cell RNA Sequencing Identifies #ProstateCancer Lineage Phenotypes Prognostic for Clinical Outcomes - by Marina Sharifi, Jamie Sperger, Shuang Zhao, Joshua Lang, and colleagues doi.org/10.1158/2159...
Thanks to the outstanding Heme/Onc and Hospice and Palliative Medicine fellows who are committed to high quality care and ongoing learning! @uwhealth.bsky.social
February 28, 2025 at 6:23 PM
Thanks to the outstanding Heme/Onc and Hospice and Palliative Medicine fellows who are committed to high quality care and ongoing learning! @uwhealth.bsky.social
Publication by @ascocancer.bsky.social on academic medical oncology. Makes me wonder- how do we encourage more transparency among institutions to set these standards ? ascopubs.org/doi/10.1200/...
Promoting Reasonable Career Expectations and Maximizing Professional Fulfillment for Academic Oncologists: ASCO Recommendations for Academic Medical Centers
In this statement, ASCO encourages academic medical centers to change their policies
and expectations to enhance and promote the professional fulfillment of academic medical
oncologists. The statement...
ascopubs.org
February 12, 2025 at 2:48 AM
Publication by @ascocancer.bsky.social on academic medical oncology. Makes me wonder- how do we encourage more transparency among institutions to set these standards ? ascopubs.org/doi/10.1200/...
Grateful to @uwbadgers.bsky.social women’s basketball team for hosting #breastcancer survivors and researchers at the game this weekend!
February 10, 2025 at 9:34 PM
Grateful to @uwbadgers.bsky.social women’s basketball team for hosting #breastcancer survivors and researchers at the game this weekend!
Reposted by Kari Wisinski, MD
Moody lab pic of me in a grim piece on this wrecking ball for biomedical research. To explain “indirects": If research is a restaurant, direct costs cover ingredients & cooks' wages. Indirect costs cover kitchen, light & heat, furniture, bookkeeper etc. Lose one, the other follows!
wapo.st/3Q9DrIH
wapo.st/3Q9DrIH
February 8, 2025 at 10:07 PM
Moody lab pic of me in a grim piece on this wrecking ball for biomedical research. To explain “indirects": If research is a restaurant, direct costs cover ingredients & cooks' wages. Indirect costs cover kitchen, light & heat, furniture, bookkeeper etc. Lose one, the other follows!
wapo.st/3Q9DrIH
wapo.st/3Q9DrIH
Last but not least, Dr. Sharifi presenting on Genomics/Precision Medicine #SABCS24 abstracts. @uwhealth.bsky.social
February 1, 2025 at 5:58 PM
Last but not least, Dr. Sharifi presenting on Genomics/Precision Medicine #SABCS24 abstracts. @uwhealth.bsky.social