@julianpollmann.bsky.social
bike maniac & research software engineer at HSD, @zdd-hsd.bsky.social
Mostly #NLP, #AI, #SoftwareEngineering
Mostly #NLP, #AI, #SoftwareEngineering
Reposted
Haftbefehl shows that Germany loves art born from alienation – just not the people who create it
Haftbefehl shows that Germany loves art born from alienation – just not the people who create it
A hit Netflix documentary about Germany’s favourite rapper demonstrates how popular the aesthetics of migrant life are – just as politicians debate how to remove it from inner cities
www.theguardian.com
November 12, 2025 at 1:43 PM
Haftbefehl shows that Germany loves art born from alienation – just not the people who create it
Reposted
New #matchms release (0.31)🚀
With functionalities that were on our TODO list for a looooong time: Flash Entropy and BLINK scores! The new "FlashSimilarity" allows computing modified cosine, spectral entropy etc., about 100x faster (or more if you use Linux).
#Python #opensource #massspec
With functionalities that were on our TODO list for a looooong time: Flash Entropy and BLINK scores! The new "FlashSimilarity" allows computing modified cosine, spectral entropy etc., about 100x faster (or more if you use Linux).
#Python #opensource #massspec
October 6, 2025 at 4:00 PM
New #matchms release (0.31)🚀
With functionalities that were on our TODO list for a looooong time: Flash Entropy and BLINK scores! The new "FlashSimilarity" allows computing modified cosine, spectral entropy etc., about 100x faster (or more if you use Linux).
#Python #opensource #massspec
With functionalities that were on our TODO list for a looooong time: Flash Entropy and BLINK scores! The new "FlashSimilarity" allows computing modified cosine, spectral entropy etc., about 100x faster (or more if you use Linux).
#Python #opensource #massspec
Reposted
4/4
We also highlight options for count fingerprints, such as log-counts and IDF weighted counts. The latter can be used to adjust the bit importance to a dataset of your choice.
An example use-case are chemical space visualizations.
Preprint: www.biorxiv.org/content/10.1...
We also highlight options for count fingerprints, such as log-counts and IDF weighted counts. The latter can be used to adjust the bit importance to a dataset of your choice.
An example use-case are chemical space visualizations.
Preprint: www.biorxiv.org/content/10.1...
June 23, 2025 at 9:22 AM
4/4
We also highlight options for count fingerprints, such as log-counts and IDF weighted counts. The latter can be used to adjust the bit importance to a dataset of your choice.
An example use-case are chemical space visualizations.
Preprint: www.biorxiv.org/content/10.1...
We also highlight options for count fingerprints, such as log-counts and IDF weighted counts. The latter can be used to adjust the bit importance to a dataset of your choice.
An example use-case are chemical space visualizations.
Preprint: www.biorxiv.org/content/10.1...
Reposted
3/4
A huge issue is bit collisions.
Fingerprints with a high bit occupation (RDKit, MAP4) often lead to (1) arbitrary misinterpretations, (2) shifts to high Tanimoto scores, (3) very different handling of small and large molecules.
--> Consider using sparse fingerprints!
--> Morgan >> MAP4 / RDKit
A huge issue is bit collisions.
Fingerprints with a high bit occupation (RDKit, MAP4) often lead to (1) arbitrary misinterpretations, (2) shifts to high Tanimoto scores, (3) very different handling of small and large molecules.
--> Consider using sparse fingerprints!
--> Morgan >> MAP4 / RDKit
June 23, 2025 at 9:22 AM
3/4
A huge issue is bit collisions.
Fingerprints with a high bit occupation (RDKit, MAP4) often lead to (1) arbitrary misinterpretations, (2) shifts to high Tanimoto scores, (3) very different handling of small and large molecules.
--> Consider using sparse fingerprints!
--> Morgan >> MAP4 / RDKit
A huge issue is bit collisions.
Fingerprints with a high bit occupation (RDKit, MAP4) often lead to (1) arbitrary misinterpretations, (2) shifts to high Tanimoto scores, (3) very different handling of small and large molecules.
--> Consider using sparse fingerprints!
--> Morgan >> MAP4 / RDKit
Reposted
2/4
We focused on weaknesses of the fingerprints.
Many show frequent duplicates, so same fingerprint for different compounds. Most problematic: this can include *very* different compounds ending up with identical fingerprints.
- MAP4 >> Morgan-type >> daylight
- count >> binary
#cheminformatics
We focused on weaknesses of the fingerprints.
Many show frequent duplicates, so same fingerprint for different compounds. Most problematic: this can include *very* different compounds ending up with identical fingerprints.
- MAP4 >> Morgan-type >> daylight
- count >> binary
#cheminformatics
June 23, 2025 at 9:22 AM
2/4
We focused on weaknesses of the fingerprints.
Many show frequent duplicates, so same fingerprint for different compounds. Most problematic: this can include *very* different compounds ending up with identical fingerprints.
- MAP4 >> Morgan-type >> daylight
- count >> binary
#cheminformatics
We focused on weaknesses of the fingerprints.
Many show frequent duplicates, so same fingerprint for different compounds. Most problematic: this can include *very* different compounds ending up with identical fingerprints.
- MAP4 >> Morgan-type >> daylight
- count >> binary
#cheminformatics
Reposted
New preprint out!
1/4
@julianpollmann.bsky.social and I went down several rabbit holes to assess some commonly used molecular fingerprints.
Bottom line: For large datasets, make an effort to select suitable settings. "We used Tanimoto" is not good enough.
--> www.biorxiv.org/content/10.1...
1/4
@julianpollmann.bsky.social and I went down several rabbit holes to assess some commonly used molecular fingerprints.
Bottom line: For large datasets, make an effort to select suitable settings. "We used Tanimoto" is not good enough.
--> www.biorxiv.org/content/10.1...
June 23, 2025 at 9:22 AM
New preprint out!
1/4
@julianpollmann.bsky.social and I went down several rabbit holes to assess some commonly used molecular fingerprints.
Bottom line: For large datasets, make an effort to select suitable settings. "We used Tanimoto" is not good enough.
--> www.biorxiv.org/content/10.1...
1/4
@julianpollmann.bsky.social and I went down several rabbit holes to assess some commonly used molecular fingerprints.
Bottom line: For large datasets, make an effort to select suitable settings. "We used Tanimoto" is not good enough.
--> www.biorxiv.org/content/10.1...
Reposted
Reposted
Wir dachten, KI würde uns irgendwann durch Terminator-Roboter versklaven. Aber wir werden durch Bequemlichkeit versklavt.
May 12, 2025 at 10:05 PM
Wir dachten, KI würde uns irgendwann durch Terminator-Roboter versklaven. Aber wir werden durch Bequemlichkeit versklavt.
Hello @pyconde.bsky.social
Curious to listen to some interesting Talks and meet new people 😀
Curious to listen to some interesting Talks and meet new people 😀
April 23, 2025 at 7:30 AM
Hello @pyconde.bsky.social
Curious to listen to some interesting Talks and meet new people 😀
Curious to listen to some interesting Talks and meet new people 😀
Reposted
First draft online version of The RLHF Book is DONE. Recently I've been creating the advanced discussion chapters on everything from Constitutional AI to evaluation and character training, but I also sneak in consistent improvements to the RL specific chapter.
rlhfbook.com
rlhfbook.com
April 16, 2025 at 7:01 PM
First draft online version of The RLHF Book is DONE. Recently I've been creating the advanced discussion chapters on everything from Constitutional AI to evaluation and character training, but I also sneak in consistent improvements to the RL specific chapter.
rlhfbook.com
rlhfbook.com
Reposted
„Bei der #SPD haben noch die Mitglieder die Chance, die Notbremse zu ziehen und den Abbau wichtiger Grundrechte zu verhindern. Wir appellieren daher an die Sozialdemokraten: Stimmt dieser Überwachungsliste nicht zu!“ 🤝👏 @ccc.de
CCC | CCC fordert Notbremse für den Überwachungskatalog im Koalitionsvertrag
Der Chaos Computer Club ist eine galaktische Gemeinschaft von Lebewesen für Informationsfreiheit und Technikfolgenabschätzung.
www.ccc.de
April 10, 2025 at 9:55 AM
Reposted
I think this is an important point that we missed the last 10y. We need to call out fiction as fiction and fighting for reality (can be boring, but it’s real).
Reality is, there is no AGI, just language models. If you think they are giving you some truth, the stupidity is on you, not the LLM.
Reality is, there is no AGI, just language models. If you think they are giving you some truth, the stupidity is on you, not the LLM.
This isn’t a report, this is a fiction writing exercise www.nytimes.com/2025/04/03/t...
April 5, 2025 at 7:16 AM
I think this is an important point that we missed the last 10y. We need to call out fiction as fiction and fighting for reality (can be boring, but it’s real).
Reality is, there is no AGI, just language models. If you think they are giving you some truth, the stupidity is on you, not the LLM.
Reality is, there is no AGI, just language models. If you think they are giving you some truth, the stupidity is on you, not the LLM.
Reposted
👨🏫 Can you help spread the word? Our community supports future #AI professionals like engineers and data analysts. With backing from PySV and Pioneers Hub, we provide students free virtual passes to Germany's top AI conference. Learn more at 2025.pycon.de/blog/free-re....
Enabling the Next Generation in AI & Open Source: Free Remote Tickets for Students at PyCon DE & PyData
Join PyCon DE & PyData 2025 in Darmstadt (Frankfurt), April 23-25! Germany’s largest Python and Data Science conference with talks, workshops, and community events like DjangoGirls and sprints. Be…
2025.pycon.de
April 5, 2025 at 7:57 AM
👨🏫 Can you help spread the word? Our community supports future #AI professionals like engineers and data analysts. With backing from PySV and Pioneers Hub, we provide students free virtual passes to Germany's top AI conference. Learn more at 2025.pycon.de/blog/free-re....
April 3, 2025 at 3:20 PM
Reposted
April 2, 2025 at 3:40 PM
Reposted
Stanford scholars introduced an open-source AI agent that learns how to navigate websites by mimicking childhood learning – an approach that could lead to more efficient, transparent, and privacy-conscious AI: hai.stanford.edu/news/an-open...
@chrmanning.bsky.social @shikharmurty.bsky.social
@chrmanning.bsky.social @shikharmurty.bsky.social
An Open-Source AI Agent for Doing Tasks on the Web | Stanford HAI
NNetNav learns how to navigate websites by mimicking childhood learning through exploration.
hai.stanford.edu
March 28, 2025 at 7:00 PM
Stanford scholars introduced an open-source AI agent that learns how to navigate websites by mimicking childhood learning – an approach that could lead to more efficient, transparent, and privacy-conscious AI: hai.stanford.edu/news/an-open...
@chrmanning.bsky.social @shikharmurty.bsky.social
@chrmanning.bsky.social @shikharmurty.bsky.social
Reposted
#IchBinHanna & der 🐘 senden 1 Botschaft in die Koalitionsverhandlungen!
#WissZeitVG
@drkeichhorn.bsky.social @kubon.bsky.social
#WissZeitVG
@drkeichhorn.bsky.social @kubon.bsky.social
March 28, 2025 at 11:23 AM
#IchBinHanna & der 🐘 senden 1 Botschaft in die Koalitionsverhandlungen!
#WissZeitVG
@drkeichhorn.bsky.social @kubon.bsky.social
#WissZeitVG
@drkeichhorn.bsky.social @kubon.bsky.social
Interesting paper on Human Cognition in the Age of #AI or how not to brainrot arxiv.org/html/2502.12...
Protecting Human Cognition in the Age of AI
arxiv.org
March 24, 2025 at 9:11 PM
Interesting paper on Human Cognition in the Age of #AI or how not to brainrot arxiv.org/html/2502.12...
Reposted
Die amerikanische Forschung ist auch für Deutschland wichtig. Das ist ja kein Wettbewerb, den wir gewinnen wollen. Wenn es anderen schlechter geht, wirkt sich das auch auf uns und unseren gesellschaftlichen Fortschritt aus.
March 24, 2025 at 1:10 PM
Die amerikanische Forschung ist auch für Deutschland wichtig. Das ist ja kein Wettbewerb, den wir gewinnen wollen. Wenn es anderen schlechter geht, wirkt sich das auch auf uns und unseren gesellschaftlichen Fortschritt aus.
Reposted
It is super weird how little reception David Golumbia's last book "Cyberlibertarianism" has had. I mean I know why, he dropped a bunch of uncomfortable truth bombs there but it's still weird how little that book is talked about. It is probably the most important book about tech in the last decade.
March 21, 2025 at 11:51 PM
It is super weird how little reception David Golumbia's last book "Cyberlibertarianism" has had. I mean I know why, he dropped a bunch of uncomfortable truth bombs there but it's still weird how little that book is talked about. It is probably the most important book about tech in the last decade.
Reposted
I helped build a government AI system. DOGE fired me, rolled the AI out to the whole agency, and implied the AI can do my job and the jobs of the others they've fired.
It can't. But, what DOGE accidentally revealed about themselves in the process is fascinating. 🧵
It can't. But, what DOGE accidentally revealed about themselves in the process is fascinating. 🧵
March 21, 2025 at 10:41 PM
I helped build a government AI system. DOGE fired me, rolled the AI out to the whole agency, and implied the AI can do my job and the jobs of the others they've fired.
It can't. But, what DOGE accidentally revealed about themselves in the process is fascinating. 🧵
It can't. But, what DOGE accidentally revealed about themselves in the process is fascinating. 🧵
Reposted
A friend pointed out that the quasi-religious way so many tech guys talk about AI is in part because they don't want to grapple with the guilt of what they do; AI is a God, AI will fix it. No need to be responsible for what you put in the world.
I can't stop thinking about that.
I can't stop thinking about that.
The most dangerous thing about AI chat bots is how many men with political power treat them *exactly* and unquestioningly like actual Ancient Greek oracles.
March 22, 2025 at 12:44 AM
A friend pointed out that the quasi-religious way so many tech guys talk about AI is in part because they don't want to grapple with the guilt of what they do; AI is a God, AI will fix it. No need to be responsible for what you put in the world.
I can't stop thinking about that.
I can't stop thinking about that.
Reposted
Heftig. Laut Datenbank sind alle meine 4 Bücher - 3 davon zusammen mit @pialamberty.bsky.social verfasst - im Datensatz enthalten.
March 20, 2025 at 1:57 PM
Heftig. Laut Datenbank sind alle meine 4 Bücher - 3 davon zusammen mit @pialamberty.bsky.social verfasst - im Datensatz enthalten.
Reposted
📢 #ACL2025NLP Student Research Workshop CFP is out 🙌
👉 2025.aclweb.org/calls/studen...
Send your paper by ⏰ May 18th, 2025 🚀 #nlproc
👉 2025.aclweb.org/calls/studen...
Send your paper by ⏰ May 18th, 2025 🚀 #nlproc
Student Research Workshop
ACL 2025 Student Research Workshop.
2025.aclweb.org
March 18, 2025 at 6:22 AM
📢 #ACL2025NLP Student Research Workshop CFP is out 🙌
👉 2025.aclweb.org/calls/studen...
Send your paper by ⏰ May 18th, 2025 🚀 #nlproc
👉 2025.aclweb.org/calls/studen...
Send your paper by ⏰ May 18th, 2025 🚀 #nlproc
Reposted
Just as an update ... 🚀 Call for Papers – CVPR 3rd Workshop on Multi-Modal Foundation Models (MMFM)
@cvprconference.bsky.social ! 🚀
🌐 sites.google.com/view/mmfm3rd...
📅 Deadline: Apr 1, 2025 (non-proceedings)
📝 Submission: cmt3.research.microsoft.com/MMFM2025
@cvprconference.bsky.social ! 🚀
🌐 sites.google.com/view/mmfm3rd...
📅 Deadline: Apr 1, 2025 (non-proceedings)
📝 Submission: cmt3.research.microsoft.com/MMFM2025
Conference Management Toolkit - Login
Microsoft's Conference Management Toolkit is a hosted academic conference management system. Modern interface, high scalability, extensive features and outstanding support are the signatures of Micros...
cmt3.research.microsoft.com
March 18, 2025 at 10:21 AM
Just as an update ... 🚀 Call for Papers – CVPR 3rd Workshop on Multi-Modal Foundation Models (MMFM)
@cvprconference.bsky.social ! 🚀
🌐 sites.google.com/view/mmfm3rd...
📅 Deadline: Apr 1, 2025 (non-proceedings)
📝 Submission: cmt3.research.microsoft.com/MMFM2025
@cvprconference.bsky.social ! 🚀
🌐 sites.google.com/view/mmfm3rd...
📅 Deadline: Apr 1, 2025 (non-proceedings)
📝 Submission: cmt3.research.microsoft.com/MMFM2025