Julia Muenzner
@juliamuenzner.bsky.social
Aneuploidy and systems biology in yeasts // using -omics on natural isolate collections 🦠💻 Postdoc with Markus Ralser @Charite in Berlin. Mom of three. she/her
Reposted by Julia Muenzner
Just published in JBC @asbmbjournals.bsky.social - HSV-1 pUL21 teaches us that the universe of protein phosphatase 1 (PP1) binders may be much larger than previously recognised: www.jbc.org/article/S002...
Bluetorial at bsky.app/profile/atom...
Viruses - is there anything they can't do? 🦠💪
Bluetorial at bsky.app/profile/atom...
Viruses - is there anything they can't do? 🦠💪
November 15, 2025 at 10:17 AM
Just published in JBC @asbmbjournals.bsky.social - HSV-1 pUL21 teaches us that the universe of protein phosphatase 1 (PP1) binders may be much larger than previously recognised: www.jbc.org/article/S002...
Bluetorial at bsky.app/profile/atom...
Viruses - is there anything they can't do? 🦠💪
Bluetorial at bsky.app/profile/atom...
Viruses - is there anything they can't do? 🦠💪
Reposted by Julia Muenzner
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
October 9, 2025 at 2:06 PM
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
What a great conference #Candida2025 was! So happy about having met so many friendly new faces, and great to have had so much interest in how we do high throughput #proteomics with natural C albicans isolates. Looking forward to fun new collaborations! Thank you @microbiologysociety.org ❤️
a cat sitting on a couch using a laptop with the word research written on the screen
ALT: a cat sitting on a couch using a laptop with the word research written on the screen
media.tenor.com
October 9, 2025 at 6:32 PM
What a great conference #Candida2025 was! So happy about having met so many friendly new faces, and great to have had so much interest in how we do high throughput #proteomics with natural C albicans isolates. Looking forward to fun new collaborations! Thank you @microbiologysociety.org ❤️
Reposted by Julia Muenzner
New preprint from the lab: we show that the ability to switch mating type was lost at least 13 times independently in the evolution of S. cerevisiae. At least 27% of isolates are heterothallic with a strong association with polyploidy and heterozygosity
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution
Evolutionary transitions in mating strategy have profound consequences for genetic variation and adaptation. In Saccharomyces cerevisiae, mating-type switching is a central feature of the life cycle t...
www.biorxiv.org
September 16, 2025 at 6:42 PM
New preprint from the lab: we show that the ability to switch mating type was lost at least 13 times independently in the evolution of S. cerevisiae. At least 27% of isolates are heterothallic with a strong association with polyploidy and heterozygosity
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Julia Muenzner
how (yeast) cells re-climb the fitness landscape when they are reprogrammed to a different telomere DNA sequences (human-like)? read the latest from @melaniadangiolo.bsky.social etal , with great help and insights from Eric Gilson, Jonas Warringer and @juliamuenzner.bsky.social (& Ralser lab)
Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The adaptive molecular landscape of reprogrammed telomeric sequences
Telomeric sequences vary across the tree of life and intimately co-evolve with telomere-binding protein complexes. However, the molecular mechanisms allowing organisms to adapt to new telomeric sequen...
www.biorxiv.org
July 3, 2025 at 10:46 AM
how (yeast) cells re-climb the fitness landscape when they are reprogrammed to a different telomere DNA sequences (human-like)? read the latest from @melaniadangiolo.bsky.social etal , with great help and insights from Eric Gilson, Jonas Warringer and @juliamuenzner.bsky.social (& Ralser lab)
Reposted by Julia Muenzner
Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The adaptive molecular landscape of reprogrammed telomeric sequences
Telomeric sequences vary across the tree of life and intimately co-evolve with telomere-binding protein complexes. However, the molecular mechanisms allowing organisms to adapt to new telomeric sequen...
www.biorxiv.org
July 3, 2025 at 8:29 AM
Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Julia Muenzner
New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...
DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM
wwwfbm.unil.ch
June 10, 2025 at 1:53 PM
New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...
Reposted by Julia Muenzner
Congratulations to our PhD student Amy Wolstenholme for winning the Poster Prize at the EMBL Drug Resistance meeting #EESDrugResistance this week
Amy's poster showed that circular DNAs providing copper resistance can be stably transmitted for hundreds of generations in yeast
Amy's poster showed that circular DNAs providing copper resistance can be stably transmitted for hundreds of generations in yeast
March 21, 2025 at 7:31 PM
Congratulations to our PhD student Amy Wolstenholme for winning the Poster Prize at the EMBL Drug Resistance meeting #EESDrugResistance this week
Amy's poster showed that circular DNAs providing copper resistance can be stably transmitted for hundreds of generations in yeast
Amy's poster showed that circular DNAs providing copper resistance can be stably transmitted for hundreds of generations in yeast
Goodbye to #EESDrugResistance @embo.org - what a fantastic conference it was! Really cool to see the overlaps between fungal, cancer, and bacterial biology. Thought I'd use the chance to say thank you to the organizers 🙏 and migrate from the evil place to #academic Bluesky at the same time.
March 22, 2025 at 1:44 PM
Goodbye to #EESDrugResistance @embo.org - what a fantastic conference it was! Really cool to see the overlaps between fungal, cancer, and bacterial biology. Thought I'd use the chance to say thank you to the organizers 🙏 and migrate from the evil place to #academic Bluesky at the same time.