Houseley Lab
@houseleylab.bsky.social
We study molecular mechanisms of ageing and adaptation.
@BabrahamInst, Cambridge, UK. Main funding @BBSRC
Views are our own.
@BabrahamInst, Cambridge, UK. Main funding @BBSRC
Views are our own.
Our new Preprint describes an improved TrAEL-seq protocol:
• Provides far better data from mammalian cells
• Includes multiplexing for higher throughput
TrAEL-seq reveals replication patterns and fork progression in unsynchronised, unlabelled and unsorted cells
www.biorxiv.org/content/10.1...
• Provides far better data from mammalian cells
• Includes multiplexing for higher throughput
TrAEL-seq reveals replication patterns and fork progression in unsynchronised, unlabelled and unsorted cells
www.biorxiv.org/content/10.1...
June 11, 2025 at 4:35 PM
Our new Preprint describes an improved TrAEL-seq protocol:
• Provides far better data from mammalian cells
• Includes multiplexing for higher throughput
TrAEL-seq reveals replication patterns and fork progression in unsynchronised, unlabelled and unsorted cells
www.biorxiv.org/content/10.1...
• Provides far better data from mammalian cells
• Includes multiplexing for higher throughput
TrAEL-seq reveals replication patterns and fork progression in unsynchronised, unlabelled and unsorted cells
www.biorxiv.org/content/10.1...
If you're at the AGE meeting don't miss the BSRA Korenchevsky Award talk from Hanane Hadj-Moussa!
Hanane's work shows that we can acheive excellent healthy ageing through metabolic rewiring, even on an unrestricted diet
Profile:
whova.com/embedded/spe...
Preprint:
www.biorxiv.org/content/10.1...
Hanane's work shows that we can acheive excellent healthy ageing through metabolic rewiring, even on an unrestricted diet
Profile:
whova.com/embedded/spe...
Preprint:
www.biorxiv.org/content/10.1...
May 12, 2025 at 8:46 AM
If you're at the AGE meeting don't miss the BSRA Korenchevsky Award talk from Hanane Hadj-Moussa!
Hanane's work shows that we can acheive excellent healthy ageing through metabolic rewiring, even on an unrestricted diet
Profile:
whova.com/embedded/spe...
Preprint:
www.biorxiv.org/content/10.1...
Hanane's work shows that we can acheive excellent healthy ageing through metabolic rewiring, even on an unrestricted diet
Profile:
whova.com/embedded/spe...
Preprint:
www.biorxiv.org/content/10.1...
Is healthy ageing possible on a normal diet?
Our latest Preprint describes metabolic re-engineering of yeast to avoid senescence
The A2A mutant we created is super-fit late in life even on a rich high glucose diet
www.biorxiv.org/content/10.1...
Our latest Preprint describes metabolic re-engineering of yeast to avoid senescence
The A2A mutant we created is super-fit late in life even on a rich high glucose diet
www.biorxiv.org/content/10.1...
March 28, 2025 at 1:18 PM
Is healthy ageing possible on a normal diet?
Our latest Preprint describes metabolic re-engineering of yeast to avoid senescence
The A2A mutant we created is super-fit late in life even on a rich high glucose diet
www.biorxiv.org/content/10.1...
Our latest Preprint describes metabolic re-engineering of yeast to avoid senescence
The A2A mutant we created is super-fit late in life even on a rich high glucose diet
www.biorxiv.org/content/10.1...
Congratulations to our PhD student Amy Wolstenholme for winning the Poster Prize at the EMBL Drug Resistance meeting #EESDrugResistance this week
Amy's poster showed that circular DNAs providing copper resistance can be stably transmitted for hundreds of generations in yeast
Amy's poster showed that circular DNAs providing copper resistance can be stably transmitted for hundreds of generations in yeast
March 21, 2025 at 7:31 PM
Congratulations to our PhD student Amy Wolstenholme for winning the Poster Prize at the EMBL Drug Resistance meeting #EESDrugResistance this week
Amy's poster showed that circular DNAs providing copper resistance can be stably transmitted for hundreds of generations in yeast
Amy's poster showed that circular DNAs providing copper resistance can be stably transmitted for hundreds of generations in yeast