JR Caldera, PhD, D(ABMM)
@jrcaldera.bsky.social
Clinical Microbiologist #ClinMicro #IDSky
Assoc. Science Director - Quest Dx Inf Disease.
UCLA ClinMicroFellowship.
Cedars-Sinai BiomedSciPhD.
Harbor-UCLA ClinLabSci. CSULB MicroBS.
🔬+🍟(posts=own opinion)
Assoc. Science Director - Quest Dx Inf Disease.
UCLA ClinMicroFellowship.
Cedars-Sinai BiomedSciPhD.
Harbor-UCLA ClinLabSci. CSULB MicroBS.
🔬+🍟(posts=own opinion)
Reposted by JR Caldera, PhD, D(ABMM)
NEW @nejm.org: We synthesized 511 recent studies on Covid-19, RSV & flu vaccines for 2025-26. With federal advisory processes disrupted, clinicians & the public need rigorous, independent evidence synthesis.
Here's what we found: 🧵
www.nejm.org/doi/full/10....
Here's what we found: 🧵
www.nejm.org/doi/full/10....
Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 | NEJM
Changes in the vaccine advisory process in the United States have disrupted immunization
guidance, which reinforces the need for independent evidence review to inform decisions
regarding immunizati...
www.nejm.org
October 30, 2025 at 4:12 PM
NEW @nejm.org: We synthesized 511 recent studies on Covid-19, RSV & flu vaccines for 2025-26. With federal advisory processes disrupted, clinicians & the public need rigorous, independent evidence synthesis.
Here's what we found: 🧵
www.nejm.org/doi/full/10....
Here's what we found: 🧵
www.nejm.org/doi/full/10....
Been a while, but I’m glad my feed is still filled with a strong community of scientists!
Wanted to share this amazing honor from ASCP as one of their 2025 40 Under Forty honorees. And also to show off this mini scientist my cousin got me. My tchotchke shelf at work is growing ☺️ #ClinMicro
Wanted to share this amazing honor from ASCP as one of their 2025 40 Under Forty honorees. And also to show off this mini scientist my cousin got me. My tchotchke shelf at work is growing ☺️ #ClinMicro
September 30, 2025 at 11:07 PM
Been a while, but I’m glad my feed is still filled with a strong community of scientists!
Wanted to share this amazing honor from ASCP as one of their 2025 40 Under Forty honorees. And also to show off this mini scientist my cousin got me. My tchotchke shelf at work is growing ☺️ #ClinMicro
Wanted to share this amazing honor from ASCP as one of their 2025 40 Under Forty honorees. And also to show off this mini scientist my cousin got me. My tchotchke shelf at work is growing ☺️ #ClinMicro
New pub alert! 🚨 my fellowship project from @uclapathology.bsky.social is finally out, and I’ll be discussing it at next Monday’s CCMID meeting if you’re interested! #ClinMicro #IDSky
Development and validation of next-generation sequencing-based clinical test for triazole resistance prediction in Aspergillus fumigatus | Journal of Clinical Microbiology
The rising rates of antifungal resistance have been expressed by many as “the silent
pandemic,” profoundly reshaping the landscape of fungal disease management. Innovations
in clinical mycology, howev...
journals.asm.org
July 2, 2025 at 7:07 PM
New pub alert! 🚨 my fellowship project from @uclapathology.bsky.social is finally out, and I’ll be discussing it at next Monday’s CCMID meeting if you’re interested! #ClinMicro #IDSky
Reposted by JR Caldera, PhD, D(ABMM)
"We will not stay silent."
IDSA President Tina Tan, MD, FIDSA, FPIDS, FAAP, joins @ameracadpeds.bsky.social, @acpimphysicians.bsky.social,
@acog.org, and @aafp.org in urging evidence-based vaccine recommendations. bit.ly/443ptQw
IDSA President Tina Tan, MD, FIDSA, FPIDS, FAAP, joins @ameracadpeds.bsky.social, @acpimphysicians.bsky.social,
@acog.org, and @aafp.org in urging evidence-based vaccine recommendations. bit.ly/443ptQw
We will not stay silent on vaccines, say leaders of five major U.S. medical associations
“We cannot and will not gamble with our patients’ health or the health of our communities,” write the presidents of the AAFP, AAP, ACP, ACOG, and IDSA.
bit.ly
June 26, 2025 at 7:16 PM
"We will not stay silent."
IDSA President Tina Tan, MD, FIDSA, FPIDS, FAAP, joins @ameracadpeds.bsky.social, @acpimphysicians.bsky.social,
@acog.org, and @aafp.org in urging evidence-based vaccine recommendations. bit.ly/443ptQw
IDSA President Tina Tan, MD, FIDSA, FPIDS, FAAP, joins @ameracadpeds.bsky.social, @acpimphysicians.bsky.social,
@acog.org, and @aafp.org in urging evidence-based vaccine recommendations. bit.ly/443ptQw
I always look forward to ASM Microbe, but 2025 was particularly special because it was hosted in my neck of the woods. I hope my colleagues got to see everything that is beautiful about Los Angeles! #ClinMicro #ASMicrobe2025
June 23, 2025 at 10:52 PM
I always look forward to ASM Microbe, but 2025 was particularly special because it was hosted in my neck of the woods. I hope my colleagues got to see everything that is beautiful about Los Angeles! #ClinMicro #ASMicrobe2025
BREAKING: RFK Jr. removes every member of scientific committee that advises the CDC on vaccine use, pledging to replace them with his own picks.
RFK Jr. ousts entire CDC vaccine advisory committee
Health Secretary Robert F. Kennedy Jr. has removed every member of a scientific committee that advises the Centers for Disease Control and Prevention on how to use vaccines.
bit.ly
June 9, 2025 at 10:29 PM
Reposted by JR Caldera, PhD, D(ABMM)
There was a cluster of #XDR #Shigella sonnei carrying blaCTX-M-15 in LA ('23-24), reported by @jrcaldera.bsky.social
While infections are usually self-limited, one of these cases was severe, in a person living with #HIV and low CD4
www.ajicjournal.org/article/S019...
@ajicjournal.bsky.social
While infections are usually self-limited, one of these cases was severe, in a person living with #HIV and low CD4
www.ajicjournal.org/article/S019...
@ajicjournal.bsky.social
Cluster of extensively drug-resistant Shigella sonnei carrying blaCTX-M-15 in Los Angeles, California, 2023 to 2024
We describe 3 cases of extensively drug-resistant Shigella sonnei infections among
men who have sex with men in Los Angeles, CA. Using whole-genome sequencing, we determined
that they are highly genet...
www.ajicjournal.org
June 6, 2025 at 10:07 AM
There was a cluster of #XDR #Shigella sonnei carrying blaCTX-M-15 in LA ('23-24), reported by @jrcaldera.bsky.social
While infections are usually self-limited, one of these cases was severe, in a person living with #HIV and low CD4
www.ajicjournal.org/article/S019...
@ajicjournal.bsky.social
While infections are usually self-limited, one of these cases was severe, in a person living with #HIV and low CD4
www.ajicjournal.org/article/S019...
@ajicjournal.bsky.social
Reposted by JR Caldera, PhD, D(ABMM)
🚨 Extensively drug-resistant #Shigella is increasing in #LosAngeles. PLWH and GBMSM are disproportionately affected.
We have seen several of these, very difficult to treat.
Antibiogram shows 📈 resistance, susceptibility testing is 🔑.
#IDsky #Medsky #EMSky #AMR #XDR
🔗: t.e2ma.net/webview/3apx...
We have seen several of these, very difficult to treat.
Antibiogram shows 📈 resistance, susceptibility testing is 🔑.
#IDsky #Medsky #EMSky #AMR #XDR
🔗: t.e2ma.net/webview/3apx...
June 6, 2025 at 10:07 AM
🚨 Extensively drug-resistant #Shigella is increasing in #LosAngeles. PLWH and GBMSM are disproportionately affected.
We have seen several of these, very difficult to treat.
Antibiogram shows 📈 resistance, susceptibility testing is 🔑.
#IDsky #Medsky #EMSky #AMR #XDR
🔗: t.e2ma.net/webview/3apx...
We have seen several of these, very difficult to treat.
Antibiogram shows 📈 resistance, susceptibility testing is 🔑.
#IDsky #Medsky #EMSky #AMR #XDR
🔗: t.e2ma.net/webview/3apx...
Reposted by JR Caldera, PhD, D(ABMM)
RFK Jr. ordered the NIH’s Integrated Research Facility in Frederick to stop all research on serious infectious diseases yesterday at 5:00 PM.
They study pathogens like Ebola there. You may be familiar with it from The Hot Zone.
www.wired.com/story/hhs-ni...
They study pathogens like Ebola there. You may be familiar with it from The Hot Zone.
www.wired.com/story/hhs-ni...
RFK Jr.'s HHS Orders Lab Studying Deadly Infectious Diseases to Stop Research
NIAID's Integrated Research Facility is one of the few federal facilities charged with studying Ebola. Tuesday afternoon, all of its work was put on indefinite pause by Robert F. Kennedy Jr.'s departm...
www.wired.com
April 30, 2025 at 10:45 PM
RFK Jr. ordered the NIH’s Integrated Research Facility in Frederick to stop all research on serious infectious diseases yesterday at 5:00 PM.
They study pathogens like Ebola there. You may be familiar with it from The Hot Zone.
www.wired.com/story/hhs-ni...
They study pathogens like Ebola there. You may be familiar with it from The Hot Zone.
www.wired.com/story/hhs-ni...
🚨New pub alert! Hot-off the press! #ClinMicro
“[Rhinovirus] was the most common viral pathogen in young
children, even during the height of the COVID-19 pandemic, and was an independent
driver of moderate-to-severe disease, particularly in children with comorbidities.”
www.mdpi.com/2036-7449/17...
“[Rhinovirus] was the most common viral pathogen in young
children, even during the height of the COVID-19 pandemic, and was an independent
driver of moderate-to-severe disease, particularly in children with comorbidities.”
www.mdpi.com/2036-7449/17...
April 3, 2025 at 5:42 PM
🚨New pub alert! Hot-off the press! #ClinMicro
“[Rhinovirus] was the most common viral pathogen in young
children, even during the height of the COVID-19 pandemic, and was an independent
driver of moderate-to-severe disease, particularly in children with comorbidities.”
www.mdpi.com/2036-7449/17...
“[Rhinovirus] was the most common viral pathogen in young
children, even during the height of the COVID-19 pandemic, and was an independent
driver of moderate-to-severe disease, particularly in children with comorbidities.”
www.mdpi.com/2036-7449/17...
Reposted by JR Caldera, PhD, D(ABMM)
“Now that the pandemic is over, the grants and cooperative agreements are no longer necessary," federal health authorities wrote to funding recipients this week.
CDC is pulling back $11B in Covid funding sent to health departments across the U.S.
“Now that the pandemic is over, the grants and cooperative agreements are no longer necessary," federal health authorities wrote to funding recipients this week.
nbcnews.to
March 25, 2025 at 7:27 PM
“Now that the pandemic is over, the grants and cooperative agreements are no longer necessary," federal health authorities wrote to funding recipients this week.
Reposted by JR Caldera, PhD, D(ABMM)
(Me flirting) Did you know microbes in the human body contribute MORE to the human body’s survival than our bodies themselves? And there are more microbial genes than human in our bodies?
We just big ol’ walkin’ terrariums.
The sauce:
www.nih.gov/news-events/...
We just big ol’ walkin’ terrariums.
The sauce:
www.nih.gov/news-events/...
NIH Human Microbiome Project defines normal bacterial makeup of the body
Genome sequencing creates first reference data for microbes living with healthy adults.
www.nih.gov
March 16, 2025 at 5:48 AM
(Me flirting) Did you know microbes in the human body contribute MORE to the human body’s survival than our bodies themselves? And there are more microbial genes than human in our bodies?
We just big ol’ walkin’ terrariums.
The sauce:
www.nih.gov/news-events/...
We just big ol’ walkin’ terrariums.
The sauce:
www.nih.gov/news-events/...
Reposted by JR Caldera, PhD, D(ABMM)
Currently, four cases of clade I mpox have been detected in this country. Our latest blog highlights how the third case was uncovered in New Hampshire and the state public health laboratory's quick response. #mpox #infectiousdisease #publichealthpreparedness #LRN
Read more:
Read more:
New Hampshire Reported the Country’s Third Clade I Mpox Case: How the State’s Public Health Laboratory System Sprung Into Action - APHL Blog
By Donna Campisano, specialist, Communications, APHL When it comes to detecting an infectious disease and launching an effective public health response, quick action is everything. And New…
buff.ly
March 12, 2025 at 8:37 PM
Currently, four cases of clade I mpox have been detected in this country. Our latest blog highlights how the third case was uncovered in New Hampshire and the state public health laboratory's quick response. #mpox #infectiousdisease #publichealthpreparedness #LRN
Read more:
Read more:
March 5, 2025 at 9:03 PM
Reposted by JR Caldera, PhD, D(ABMM)
CDC Staff Prohibited From Co-Authoring Papers With World Health Organization Personnel
CDC Staff Prohibited From Co-Authoring Papers With World Health Organization Personnel
It’s just the latest “Orwellian” crackdown on government scientists.
www.huffingtonpost.co.uk
March 3, 2025 at 1:25 PM
CDC Staff Prohibited From Co-Authoring Papers With World Health Organization Personnel
New retrospective eval of 1000 Karius tests
Clinical impact: positive 16%, negative 2%, none 82%(!)
Cx neg IE and fastidious/zoonotic/vector-borne increased likelihood of positive impact, but not immunocompromised status
#IDSky @ichejournal.bsky.social
pubmed.ncbi.nlm.nih.gov/39881594/
Clinical impact: positive 16%, negative 2%, none 82%(!)
Cx neg IE and fastidious/zoonotic/vector-borne increased likelihood of positive impact, but not immunocompromised status
#IDSky @ichejournal.bsky.social
pubmed.ncbi.nlm.nih.gov/39881594/
January 31, 2025 at 10:24 PM
Reposted by JR Caldera, PhD, D(ABMM)
Scientists and Physicians
I’m being serious here —at this precarious juncture, along with all other defensive and support strategies, it is important to seize the public narrative—high level investment and leadership in medical discovery and innovation is unabashedly patriotic!
USA! USA! USA!
I’m being serious here —at this precarious juncture, along with all other defensive and support strategies, it is important to seize the public narrative—high level investment and leadership in medical discovery and innovation is unabashedly patriotic!
USA! USA! USA!
January 24, 2025 at 12:53 PM
Scientists and Physicians
I’m being serious here —at this precarious juncture, along with all other defensive and support strategies, it is important to seize the public narrative—high level investment and leadership in medical discovery and innovation is unabashedly patriotic!
USA! USA! USA!
I’m being serious here —at this precarious juncture, along with all other defensive and support strategies, it is important to seize the public narrative—high level investment and leadership in medical discovery and innovation is unabashedly patriotic!
USA! USA! USA!
Reposted by JR Caldera, PhD, D(ABMM)
Following the withdrawal from the WHO, pausing communication from government health agencies is very concerning. #idsky www.cnn.com/2025/01/21/h...
Trump administration directs federal health agencies to pause communications | CNN
Amid a deluge of executive actions, the Trump administration has directed federal health agencies to pause external communications, such as regular scientific reports, updates to websites and health a...
www.cnn.com
January 22, 2025 at 7:09 PM
Following the withdrawal from the WHO, pausing communication from government health agencies is very concerning. #idsky www.cnn.com/2025/01/21/h...
Reposted by JR Caldera, PhD, D(ABMM)
Just did a lecture on COVID-19/surveillance systems in my infectious disease epidemiology course. Withdrawing would be a major blow to global #PublicHealth...
From @sherylnyt.bsky.social in @nytimes.com
www.nytimes.com/2025/01/20/u...
From @sherylnyt.bsky.social in @nytimes.com
www.nytimes.com/2025/01/20/u...
Trump Withdraws U.S. from World Health Organization
Public health experts say U.S. withdrawal from the W.H.O. would undermine the nation’s standing as a global health leader and make it harder to fight the next pandemic.
www.nytimes.com
January 21, 2025 at 3:02 PM
Just did a lecture on COVID-19/surveillance systems in my infectious disease epidemiology course. Withdrawing would be a major blow to global #PublicHealth...
From @sherylnyt.bsky.social in @nytimes.com
www.nytimes.com/2025/01/20/u...
From @sherylnyt.bsky.social in @nytimes.com
www.nytimes.com/2025/01/20/u...
December 19, 2024 at 4:03 AM
I former colleague of mine said our article was picked up by his favorite tech site!
And here it is! 😯😁
#ClinMicro #IDSky
And here it is! 😯😁
#ClinMicro #IDSky
'Alarming': A Dangerous Diarrhea-Causing Superbug Is Spreading in Los Angeles https://gizmodo.com/alarming-a-dangerous-diarrhea-causing-superbug-is-spreading-in-los-angeles-2000539235
'Alarming': A Dangerous Diarrhea-Causing Superbug Is Spreading in Los Angeles
An novel and extensively drug-resistant strain of Shigella sonnei has emerged and is likely still actively spreading in the U.S., scientists warn.
gizmodo.com
December 17, 2024 at 5:09 AM
I former colleague of mine said our article was picked up by his favorite tech site!
And here it is! 😯😁
#ClinMicro #IDSky
And here it is! 😯😁
#ClinMicro #IDSky