John Price
jpricephysics.bsky.social
John Price
@jpricephysics.bsky.social
Physicist, retired professor, maker of NMR spectrometers, struggling flute player
Highest field NMR available outside of a superconducting magnet #Chemistry #Chemsky
At 125 MHz, benchtop NMR highlights the aromatic region of diclofenac sodium, a common NSAID used to treat pain and inflammation. Downfield aromatic signals reflect deshielding from the dichloro rings, where chlorine’s electron-withdrawing effects shift protons further downfield.🧪 #NMRchat #Chemsky
January 15, 2026 at 8:12 PM
Reposted by John Price
T₁ inversion-recovery is a key first step in qNMR, defining optimal delay times to balance accuracy and speed. With 125 MHz performance and high resolution, the QM-125 is ready for qNMR—learn more in our latest application note.
www.qmagnetics.com/app-note-arr...
🧪 #NMRchat #Chemistry #Chemsky
January 9, 2026 at 7:12 PM
Here’s something new for 2026! #Chemistry #NMR @qmagnetics.bsky.social
Our New Year's resolution at Q Magnetics is 0.33 Hz FWHM with the highest benchtop NMR dispersion available. This figure demonstrates a single-scan limit-of-detection of 21 nmol, with a total sample volume of just 4.3 μL. #NMRchat #Chemisty #Chemsky
December 31, 2025 at 5:36 PM
Reposted by John Price
BlueSky Magnetic Resonance Starter Packs #NMRchat #NMR #MRI #EPR #ESR 🧲
Magnetic Resonance bsky.app/starter-pack...
NMRchat bsky.app/starter-pack...
MagRes bsky.app/starter-pack...
EPR-ESR Spectroscopy bsky.app/starter-pack...
December 22, 2025 at 8:21 PM
This is the CECOT 60 Minutes segment that CBS and the Trump administartion don’t want you to see. ia801703.us.archive.org/32/items/60m...
ia801703.us.archive.org
December 23, 2025 at 1:44 AM
Something new: COSY on the benchtop at 125 MHz! We can do it with or without deuterium, and with sample volumes down to 5 uL. As far as I know, this is the highest field COSY so far not done in a superconducting magnet. #Chemsky #NMR #Chemistry
The Q Magnetics team wishes our friends around the world a safe and COSY holiday season. #Chemsky #NMR #NMRchat
December 16, 2025 at 12:46 AM
At 125 MHz, benchtop NMR shows how the chiral center in (4S)-4-(propan-2-yl)-1,3-oxazolidin-2-one induces nonequivalence in nearby protons, producing diastereotopic splitting. As an Evans-type chiral auxiliary, it directs enolate geometry in asymmetric synthesis.🧪
#NMRchat #Flowchemistry #Chemistry
December 11, 2025 at 8:37 PM
Reposted by John Price
At 125 MHz, benchtop NMR shows how the chiral center in (4S)-4-(propan-2-yl)-1,3-oxazolidin-2-one induces nonequivalence in nearby protons, producing diastereotopic splitting. As an Evans-type chiral auxiliary, it directs enolate geometry in asymmetric synthesis.🧪
#NMRchat #Flowchemistry #Chemistry
December 11, 2025 at 5:55 PM
I tried Vineeth’s PyOR NMR package by making these sims of COSY and P.COSY with SHR and TPPI processing. You can see how TPPI moves T1 noise to the edge of the spectrum and how P.COSY narrows diagonal peaks. PyOR is instructive and easy to use. Check it out! #Chemsky #NMR @vthalakottoor.bsky.social
Here are PyOR tutorials on COSY (States-Haberkorn-Ruben and TPPI methods) by John Price @jpricephysics.bsky.social (Q Magnetics).

github.com/VThalakottoo...

If anyone is interested in making PyOR tutorials about NMR experiments, you are always welcome.

#NMR #NMRchat #PyOR
December 9, 2025 at 6:05 AM
It's a snow day here and I'm at home working on the Q Magnetics spectrometer software. I have all the QM-125 electronics here but no magnet or probe. However, I do have a 126.02 MHz quartz crystal. It makes a nice "FID"! I can see that the crystal many spurious modes. #NMRchat #NMR #Chemsky
December 3, 2025 at 9:47 PM
This one surprised me. With benchtop NMR at 125 MHz, you can cleanly separate the main spectral features of oleic acid. #ChemSky #NMRchat
At 125 MHz, benchtop NMR reveals how oleic acid’s cis double bond shapes its spectrum, with downfield vinylic and nearby allylic signals standing out from the aliphatic chain. Oleic acid is a key lipid in membranes and a major metabolic energy source.
🧪
#NMRchat #Flowchemistry #Chemistry
December 1, 2025 at 8:27 PM
I know this old scope’s days are numbered, but it’s been a good ride
November 27, 2025 at 8:29 PM
New app note: 125 MHz benchtop NMR for reaction monitoring and lab automation #ChemSky #NMR #NMRchat
See how the QM-125 makes benchtop NMR automation practical. Our application note shows a pump-driven, Python-controlled Fischer esterification reaction with clear reactant, intermediate, and product profiles. Visit www.qmagnetics.com/blog to learn more. 🧪
#NMRchat #flowchemistry #Automation
November 21, 2025 at 8:59 PM
3 Tesla fluorine benchtop NMR for perfluoroalkanes! #NMRchat #NMR #chemistry @qmagnetics.bsky.social
Interested in characterizing forever chemicals by benchtop NMR? The ¹⁹F NMR of 1H,1H,2H,2H-perfluorodecyl acetate on the QM-125 highlights its low-tension, hydrophobic, stable nature. ¹⁹F NMR helps reveal PFAS chain signals right on the bench.
🧪 #NMRchat #Chemistry #BenchtopNMR #FluorineNMR
November 14, 2025 at 5:15 PM
Believe it or not, you can still buy a new Simpson meter. The product line is about 90 years old. #electronics #engineeering
November 8, 2025 at 3:13 PM
Q Magnetics at the Powerhouse Energy Campus #NMRchat #Chemsky
We’re proud to support local research efforts at the CSU Powerhouse Energy Campus, where the QM-125 NMR now provides everyday NMR accessibility to a research group. They will soon be using it for tracking electrochemical reactions, advancing their research within their own lab. #NMRchat #benchtopNMR
November 7, 2025 at 7:37 PM
I’m definitely doing this next year
November 1, 2025 at 9:34 PM
Did you know you can use 125 MHz benctop NMR to measure isotopic ratios? #NMRchat #NMR #ChemSky
Check out the ¹⁹F NMR spectrum of NaBF₄ at 3 T. Coupling of ¹⁹F to ¹¹B gives a quartet, while ¹⁰B yields a septet. The ¹¹B quartet dominates due to its higher natural abundance. The difference in multiplicity creates a beautiful example of ¹⁹F – ¹⁰/¹¹B coupling! #NMRchat #Chemistry #FluorineNMR
October 30, 2025 at 7:21 PM
If you need to change the sample tube in the Q Magnetics 125 MHz NMR spectrometer, it will only take a few minutes. With sample-delivery-by-flow, you are ready for both walk-up use and automated applications. #NMR #NMRchat @qmagnetics.bsky.social
October 23, 2025 at 4:12 PM
Longmont CO was lookin’ pretty progressive today!
Hugely big showing in Longmont CO for #NoKings peaceful protest gathering
October 19, 2025 at 2:24 AM
Reposted by John Price
Also check out the invited speakers for ENC #ENC2026: www.enc-conference.org/ENC-Invited-...
ENC - Experimental Nuclear Magnetic Resonance Conference - Invited Speakers
www.enc-conference.org
October 19, 2025 at 1:50 AM
Reposted by John Price
October 18, 2025 at 11:55 AM
The proton triplet might fool you into thinking that the H-F ortho and meta J-couplings are equal. But nooooo
125 MHz 1,4-difluorobenzene proton and fluorine multiplets appear first-order with equal J-couplings, even though the protons are not magnetically equivalent. Observed splitting of 6.08 Hz in both multiplets is close to the average of these couplings.🧪 #NMRchat #chemistry #benchtopnmr
October 16, 2025 at 6:36 PM
Catastrophe
I don’t know who needs to hear this but the CDC is being eviscerated right now. America is not going to have any kind of outbreak response capacity after tonight. Americans’ health data is no longer secure. Say goodbye to federal public health in any capacity. It’s a disaster. We won’t recover.
October 11, 2025 at 5:08 AM