Jon Magne Letnes
@jonmagne.bsky.social
Cardiology resident and researcher🫀
Interests: exercise in AF (NEXAF Trial), cardiovascular physiology, sports cardiology (and mostly everything cardiology)
Interests: exercise in AF (NEXAF Trial), cardiovascular physiology, sports cardiology (and mostly everything cardiology)
Reposted by Jon Magne Letnes
Difficult to overstate how much blood RFK and Trump will have on their hands in the coming years.
Difficult to overstate how many innocent kids will die as a result of the people who cast votes for Trump last November.
Difficult to overstate how many innocent kids will die as a result of the people who cast votes for Trump last November.
A chilling reminder that American science denial does not just affect people in the US, it kills people globally.
June 26, 2025 at 4:34 AM
Difficult to overstate how much blood RFK and Trump will have on their hands in the coming years.
Difficult to overstate how many innocent kids will die as a result of the people who cast votes for Trump last November.
Difficult to overstate how many innocent kids will die as a result of the people who cast votes for Trump last November.
300 implanted ILRs and well into the one-year follow-up for the last included participants.
Will one year of exercise impact arrhythmia burden in AF patients?
So happy to share our protocol paper for the NEXAF Trial: openheart.bmj.com/content/12/1... #cardiosky
Will one year of exercise impact arrhythmia burden in AF patients?
So happy to share our protocol paper for the NEXAF Trial: openheart.bmj.com/content/12/1... #cardiosky
Effects of 1-year exercise in patients with atrial fibrillation: study protocol for the Norwegian Exercise in Atrial Fibrillation (NEXAF) randomised controlled trial
Introduction Atrial fibrillation is the most prevalent sustained arrhythmia worldwide and is expected to increase substantially within the coming years. Although lifestyle changes and risk factor modi...
openheart.bmj.com
March 24, 2025 at 8:25 AM
300 implanted ILRs and well into the one-year follow-up for the last included participants.
Will one year of exercise impact arrhythmia burden in AF patients?
So happy to share our protocol paper for the NEXAF Trial: openheart.bmj.com/content/12/1... #cardiosky
Will one year of exercise impact arrhythmia burden in AF patients?
So happy to share our protocol paper for the NEXAF Trial: openheart.bmj.com/content/12/1... #cardiosky
Reposted by Jon Magne Letnes
Since coming back from @nmerke.bsky.social‘s great 3D-Workshop I‘ve been thinking about MR quantification - volumetric, VC, PISA - and why I haven’t been so enthusiastic about it lately. A thread…
January 26, 2025 at 12:47 PM
Since coming back from @nmerke.bsky.social‘s great 3D-Workshop I‘ve been thinking about MR quantification - volumetric, VC, PISA - and why I haven’t been so enthusiastic about it lately. A thread…
Reposted by Jon Magne Letnes
IVR has constant volume, but shape change. All parts of the ventricle relax, but the apex relaxes most, and hence is most Energy demanding, the shortening of the base is not wasted work. The reconfiguration generates apical flow, giving momentum to the subsequent early filling
January 3, 2025 at 10:10 AM
IVR has constant volume, but shape change. All parts of the ventricle relax, but the apex relaxes most, and hence is most Energy demanding, the shortening of the base is not wasted work. The reconfiguration generates apical flow, giving momentum to the subsequent early filling
Reposted by Jon Magne Letnes
#EHJCVI 🏋️ Diastolic function and dysfunction in athletes
⚽️ Cardiac remodeling ➡️ chamber enlargement ➕ hypertrophy
💡#Echofirst ➡️ Dilated #LV ➕ Normal #EF ➕ Enlarged #LA ➕ ⬆️E/A
🚩Careful interpretation of diastolic function parameters
Read more 👉 doi.org/10.1093/ehjc... #CardioSky
⚽️ Cardiac remodeling ➡️ chamber enlargement ➕ hypertrophy
💡#Echofirst ➡️ Dilated #LV ➕ Normal #EF ➕ Enlarged #LA ➕ ⬆️E/A
🚩Careful interpretation of diastolic function parameters
Read more 👉 doi.org/10.1093/ehjc... #CardioSky
Diastolic function and dysfunction in athletes
Abstract. Cardiac remodelling is often most profound in male athletes and in athletes with the greatest volumes of endurance training and is characterized
doi.org
November 16, 2024 at 9:33 PM
#EHJCVI 🏋️ Diastolic function and dysfunction in athletes
⚽️ Cardiac remodeling ➡️ chamber enlargement ➕ hypertrophy
💡#Echofirst ➡️ Dilated #LV ➕ Normal #EF ➕ Enlarged #LA ➕ ⬆️E/A
🚩Careful interpretation of diastolic function parameters
Read more 👉 doi.org/10.1093/ehjc... #CardioSky
⚽️ Cardiac remodeling ➡️ chamber enlargement ➕ hypertrophy
💡#Echofirst ➡️ Dilated #LV ➕ Normal #EF ➕ Enlarged #LA ➕ ⬆️E/A
🚩Careful interpretation of diastolic function parameters
Read more 👉 doi.org/10.1093/ehjc... #CardioSky
Reposted by Jon Magne Letnes
A case of exactly what I mentioned in my last post. When things don’t fit, get better images with better equipment and/or more experienced people involved. #emimcc #cardiosky #echosky #pocus
1w cough and increasing dyspnea. Upon pickup by paramedics sat70%, hypotensive. ⬆️CRP/WBC. Pneumonia/septic shock assumed, abx and bolus fluids initiated, intubated in the ER. Hypotensive despite high dose pressor, #Echo follows #FOAMed #FOAMcc
November 26, 2024 at 5:37 PM
A case of exactly what I mentioned in my last post. When things don’t fit, get better images with better equipment and/or more experienced people involved. #emimcc #cardiosky #echosky #pocus
Reposted by Jon Magne Letnes
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience 👩🔬🥼🧪 #CardioSky #Cardiomyopathy #cardiorenal #cardiovascular #cardiovasculardisease 👇👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience - Nature Genetics
Genome-wide association and multitrait analyses for dilated cardiomyopathy (DCM) using 9,365 cases and 946,368 controls provide insights into the mechanisms underlying DCM and myocardial resilience
www.nature.com
November 24, 2024 at 2:05 PM
Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience 👩🔬🥼🧪 #CardioSky #Cardiomyopathy #cardiorenal #cardiovascular #cardiovasculardisease 👇👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Love this stuff!
Reposting an old thread on the history of MAPSE! The first to recognise long axis movement as the primary movement of the heart was none other than da Vinci! #echosky #pocus #medsky # #cardiosky www.onlinejase.com/article/S089...
November 22, 2024 at 5:55 PM
Love this stuff!
Reposted by Jon Magne Letnes
Very interesting study comparing standard anticoagulation to Watchman atrial closure after atrial fibrillation ablation, should garner lots of discussion! Lower bleeding rates, no difference in stroke risk. #cardiosky #medsky #AHA24 www.nejm.org/doi/full/10....
Left Atrial Appendage Closure after Ablation for Atrial Fibrillation | NEJM
Oral anticoagulation is recommended after ablation for atrial fibrillation among patients at high risk for stroke. Left atrial appendage closure is a mechanical alternative to anticoagulation, but ...
www.nejm.org
November 16, 2024 at 10:23 PM
Very interesting study comparing standard anticoagulation to Watchman atrial closure after atrial fibrillation ablation, should garner lots of discussion! Lower bleeding rates, no difference in stroke risk. #cardiosky #medsky #AHA24 www.nejm.org/doi/full/10....
Thanks for sharing 🙏 Have a look at our review on diastolic dysfunction in athletes ⬇️
#EHJCVI 🏋️ Diastolic function and dysfunction in athletes
⚽️ Cardiac remodeling ➡️ chamber enlargement ➕ hypertrophy
💡#Echofirst ➡️ Dilated #LV ➕ Normal #EF ➕ Enlarged #LA ➕ ⬆️E/A
🚩Careful interpretation of diastolic function parameters
Read more 👉 doi.org/10.1093/ehjc... #CardioSky
⚽️ Cardiac remodeling ➡️ chamber enlargement ➕ hypertrophy
💡#Echofirst ➡️ Dilated #LV ➕ Normal #EF ➕ Enlarged #LA ➕ ⬆️E/A
🚩Careful interpretation of diastolic function parameters
Read more 👉 doi.org/10.1093/ehjc... #CardioSky
Diastolic function and dysfunction in athletes
Abstract. Cardiac remodelling is often most profound in male athletes and in athletes with the greatest volumes of endurance training and is characterized
doi.org
November 16, 2024 at 9:51 PM
Thanks for sharing 🙏 Have a look at our review on diastolic dysfunction in athletes ⬇️
Reposted by Jon Magne Letnes
Congratulations to @johnlsapp on the presentation and publication of VANISH-2.
First line VT ablation is associated with significant reduction in composite of death, VT, storm for patients with ischemic cardiomyopathy.
www.nejm.org/doi/full/10....
First line VT ablation is associated with significant reduction in composite of death, VT, storm for patients with ischemic cardiomyopathy.
www.nejm.org/doi/full/10....
November 16, 2024 at 7:50 PM
Congratulations to @johnlsapp on the presentation and publication of VANISH-2.
First line VT ablation is associated with significant reduction in composite of death, VT, storm for patients with ischemic cardiomyopathy.
www.nejm.org/doi/full/10....
First line VT ablation is associated with significant reduction in composite of death, VT, storm for patients with ischemic cardiomyopathy.
www.nejm.org/doi/full/10....
Long time since last update: we implanted ILR number 300 in August, and >50% have completed the 1-year trial!
Hope you are ready for hot, new data on the effects of exercise on AF burden in the not so distant future 🤓🫀 #NEXAF #afib
Hope you are ready for hot, new data on the effects of exercise on AF burden in the not so distant future 🤓🫀 #NEXAF #afib
1/ One year since last progress update in the @NEXAF1 Trial randomizing inactive atrial fibrillation patients to exercise vs usual care. Tuesday we implanted the 158th loop recorder, and yesterday patient no 24 completed the one-year follow-up🏃♂️🏃♀️
Busy last months, but nice to see inclusion to NEXAF trial on exercise in atrial fibrillation getting up to speed. First 40 loop recorders implanted and first patients randomised to exercise well into the intervention already! Only a few hundred more to go.. #CardioTwitter
November 16, 2024 at 7:34 PM
Reposted by Jon Magne Letnes
1/
BPROAD (N=12821)
F/U 4.2y
SBP delta: 16.7 (118.3 vs 135 median)
A1C at 48m = 7.6%
PEP (CV death, MI, stroke or HF):
393 vs 492, 0.79, 0.69-0.90
ARD = 1.55% (6.13% vs 7.68%)
PEP driven by stroke: 284 vs 356, HR 0.79, 0.67-0.92
Stroke dominated PEP
No diff. in serious AE
BPROAD (N=12821)
F/U 4.2y
SBP delta: 16.7 (118.3 vs 135 median)
A1C at 48m = 7.6%
PEP (CV death, MI, stroke or HF):
393 vs 492, 0.79, 0.69-0.90
ARD = 1.55% (6.13% vs 7.68%)
PEP driven by stroke: 284 vs 356, HR 0.79, 0.67-0.92
Stroke dominated PEP
No diff. in serious AE
November 16, 2024 at 3:07 PM
1/
BPROAD (N=12821)
F/U 4.2y
SBP delta: 16.7 (118.3 vs 135 median)
A1C at 48m = 7.6%
PEP (CV death, MI, stroke or HF):
393 vs 492, 0.79, 0.69-0.90
ARD = 1.55% (6.13% vs 7.68%)
PEP driven by stroke: 284 vs 356, HR 0.79, 0.67-0.92
Stroke dominated PEP
No diff. in serious AE
BPROAD (N=12821)
F/U 4.2y
SBP delta: 16.7 (118.3 vs 135 median)
A1C at 48m = 7.6%
PEP (CV death, MI, stroke or HF):
393 vs 492, 0.79, 0.69-0.90
ARD = 1.55% (6.13% vs 7.68%)
PEP driven by stroke: 284 vs 356, HR 0.79, 0.67-0.92
Stroke dominated PEP
No diff. in serious AE
Reposted by Jon Magne Letnes
Periodic reminder that liking a post is nice and appreciated, but does nothing to increase visibility in general, you need to retweet/reskeet/retoot what you want others to see.
November 14, 2024 at 10:00 AM
Periodic reminder that liking a post is nice and appreciated, but does nothing to increase visibility in general, you need to retweet/reskeet/retoot what you want others to see.
Nice way to get into #cardiosky!
Just added member nr 100 to #cardiosky starter pack, we’re growing fast! go.bsky.app/562nfhZ
November 14, 2024 at 7:43 PM
Nice way to get into #cardiosky!
Reposted by Jon Magne Letnes
Just added member nr 100 to #cardiosky starter pack, we’re growing fast! go.bsky.app/562nfhZ
November 13, 2024 at 9:54 PM
Just added member nr 100 to #cardiosky starter pack, we’re growing fast! go.bsky.app/562nfhZ
Time to leave Elon alone. Hope to see the same community here as twitter once was! #cardiosky
November 14, 2024 at 7:34 PM
Time to leave Elon alone. Hope to see the same community here as twitter once was! #cardiosky
Reposted by Jon Magne Letnes
It’s great that journals are coming over here, but what I have really missed after my departure from Twitter 2 years ago is this, the authors themselves presenting their works and discussing it with peers. #cardiosky #medsky #emimcc
In 2019, we wrote a paper showing that patients with left ventricular thrombus have a long-term risk of embolism, extending to at least 8 years.
We were puzzled by the finding…
#CardioSky
www.ahajournals.org/doi/10.1161/...
We were puzzled by the finding…
#CardioSky
www.ahajournals.org/doi/10.1161/...
November 13, 2024 at 3:58 PM
It’s great that journals are coming over here, but what I have really missed after my departure from Twitter 2 years ago is this, the authors themselves presenting their works and discussing it with peers. #cardiosky #medsky #emimcc
Bradycardia is common due to large stroke volumes in athletes. But what if the heart rate is high at echo exam? Would the LV EF go⬇️ to reduce energy waste and an unnecessary high cardiac output? We hypothesized so in our recent research letter @EJPCEiC...
November 16, 2024 at 8:51 AM
Bradycardia is common due to large stroke volumes in athletes. But what if the heart rate is high at echo exam? Would the LV EF go⬇️ to reduce energy waste and an unnecessary high cardiac output? We hypothesized so in our recent research letter @EJPCEiC...
Session start at Research Gateway station 1 at 11🔥 #ESCCongress
November 16, 2024 at 9:05 AM
Session start at Research Gateway station 1 at 11🔥 #ESCCongress
Wondering if high-intensity exercise triggers atrial fibrillation episodes? Don't miss out on @BergSellevold's presentation on observational findings from HIIT sessions w/impl ILR's from the NEXAF Trial - tomorrow morning at the #ESCCongress @NEXAF1...
November 16, 2024 at 8:51 AM
Wondering if high-intensity exercise triggers atrial fibrillation episodes? Don't miss out on @BergSellevold's presentation on observational findings from HIIT sessions w/impl ILR's from the NEXAF Trial - tomorrow morning at the #ESCCongress @NEXAF1...
Wondering how to and how not to assess diastolic function in athletes? Have a look at our recently published review on diastolic function and dysfunction in athletes in @ESC_Journals
https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeae155/7716359
...
https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeae155/7716359
...
November 16, 2024 at 9:05 AM
Wondering how to and how not to assess diastolic function in athletes? Have a look at our recently published review on diastolic function and dysfunction in athletes in @ESC_Journals
https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeae155/7716359
...
https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeae155/7716359
...
Worth a read: the development of clinical Doppler echocardiography
https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeae042/7659538?login=true&utm_source=eTOC&utm_campaign=EHJ_Cardiovascular_Imaging&utm_medium=Email
https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeae042/7659538?login=true&utm_source=eTOC&utm_campaign=EHJ_Cardiovascular_Imaging&utm_medium=Email
November 16, 2024 at 9:12 AM
Worth a read: the development of clinical Doppler echocardiography
https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeae042/7659538?login=true&utm_source=eTOC&utm_campaign=EHJ_Cardiovascular_Imaging&utm_medium=Email
https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeae042/7659538?login=true&utm_source=eTOC&utm_campaign=EHJ_Cardiovascular_Imaging&utm_medium=Email
Really interesting case/cause of recurrant ventricular arrythmia from colleagues in Trondheim.. eventually ending up in court!
Must be something for @jtrebach🤓
#CardioTwitter #EPeeps
https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-023-04304-2
Must be something for @jtrebach🤓
#CardioTwitter #EPeeps
https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-023-04304-2
Recurrent malignant ventricular arrhythmias and paresthes...
Background We report a case of a clinical challenge lasti...
jmedicalcasereports.biomedcentral.com
November 16, 2024 at 9:20 AM
Really interesting case/cause of recurrant ventricular arrythmia from colleagues in Trondheim.. eventually ending up in court!
Must be something for @jtrebach🤓
#CardioTwitter #EPeeps
https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-023-04304-2
Must be something for @jtrebach🤓
#CardioTwitter #EPeeps
https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-023-04304-2