Joni Coleman
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jonicoleman.bsky.social
Joni Coleman
@jonicoleman.bsky.social
Senior Lecturer in Statistical Genetics at KCL.
Group GitHub: https://github.com/ColemanResearchGroup/GroupInfoPublic. Views own. He/Him
Pinned
Standard disclaimer: conference bleets are eye-witness accounts and should be treated as such, with all the Loftus effects and reliability concerns that involves: www.scientificamerican.com/article/do-t...

I don't bleet Q&As.
Why Science Tells Us Not to Rely on Eyewitness Accounts
Eyewitness testimony is fickle and, all too often, shockingly inaccurate
www.scientificamerican.com
Out earlier this week in @natgenet.nature.com: GWAS of major anxiety disorders in 122,341 European-ancestry cases identifying 58 loci (www.nature.com/articles/s41...)

Awesome work, and great news for the anx genetics community — each @pgcgenetics.bsky.social paper seeds 100s more papers!
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling - Nature Genetics
Genome-wide association meta-analysis identifies 58 independent risk loci for major anxiety disorders among individuals of European ancestry and implicates GABAergic signaling as a potential mechanism...
www.nature.com
February 6, 2026 at 5:15 PM
Reposted by Joni Coleman
www.nature.com/articles/s41... 🧪. Impressive GWAS meta-analysis from the Anxiety Disorders Working Group of the Psychiatric Genomics Consortium
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling - Nature Genetics
Genome-wide association meta-analysis identifies 58 independent risk loci for major anxiety disorders among individuals of European ancestry and implicates GABAergic signaling as a potential mechanism...
www.nature.com
February 5, 2026 at 12:09 PM
Interested in how mental health develops?

If your background is in psychology, biosciences, or a related field, our MSc in Developmental Psychology & Psychopathology at @kingsioppn.bsky.social could be your next step: www.kcl.ac.uk/study/postgr...

Join us in September – reach out to learn more!
Developmental Psychology & Psychopathology | King's College London
This course will develop your knowledge about genetic and environmental causes of developmental psychopathology across the lifespan.
www.kcl.ac.uk
January 23, 2026 at 3:48 PM
Reposted by Joni Coleman
Are you seeking a PhD in genomics or the application of AI to healthcare and therapeutics?

Check out KCL's new PhD programme in Genome Data Science for Therapeutic Target Discovery!

Apply by Saturday 28th February 2026, 23:59 GMT

Details and projects: www.kcl.ac.uk/research/tar...
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
January 23, 2026 at 3:36 PM
Finally, Jennifer Asimit will discuss leveraging phenotypic similarity and ancestry diversity in cardiometabolic genetics.

Multi trait and multi ancestry methods for fine-mapping are emerging but challenging to implement
January 8, 2026 at 5:08 PM
Final session - Gareth Hawkes talks about using WGS to examine the convergence of rare and common traits.

Preprint: www.biorxiv.org/content/10.1...
Whole-genome sequencing analysis of anthropometric traits in 672,976 individuals reveals convergence between rare and common genetic associations
Genetic association studies have mostly focussed on common variants from genotyping arrays or rare protein-coding variants from exome sequencing. Here, we used whole-genome sequence (WGS) data in 672,...
www.biorxiv.org
January 8, 2026 at 4:43 PM
There are now flash talks... I will try to keep up.

First is Hannah Li talking about atherosclerosis. WES of carotid-intima media thickness min/mean/max. 47k participants. Single variant + gene based rare variant testing. Functional admission and fine-mapping. Compared with previous GWAS.
January 8, 2026 at 3:58 PM
Next is Oyesola Ojewunmi discussing foetal haemoglobin (HbF) persistence in sickle cell disease (SCD).

SCD is a disease of haemoglobin, with HbA replaced by HbS, causing sickling of the haemoglobin, deforming the blood cell and causing occlusions in vessels and downstream stroke and other sequelae
January 8, 2026 at 3:36 PM
Reposted by Joni Coleman
📢 Calling UK mental health professionals working with neurodivergent young adults 📢

Please take part in our research on depression in neurodivergent young adults!

It involves 1 individual interview and 2 focus groups (all online, £25/hour).

Sign-up link: shorturl.at/r3HlO

Reposts appreciated 🙏
January 8, 2026 at 2:51 PM
Back after TOO MUCH COFFEEEE

Onto ECR talks. First up is Eyad Elbahtety who will talk about Rare Variants in GWAS.

Rare variants are neglected in GWAS because they are hard to measure with sufficient precision given typical sample sizes
January 8, 2026 at 3:09 PM
Now Geli Ronald will talk about a genome wide association study of age at onset walking.

Why study this age? Critical period for environment, rapid onset of developmental milestones and brain changes. Arguably under appreciated in common variant genetics.
January 8, 2026 at 2:15 PM
Reposted by Joni Coleman
Nice short preprint proposing a new method to distinguish second degree relatives: half siblings vs niece/nephew avuncular pairs.

Both relationships have genomic kinship of 1/4, but they can be distinguished by multiple signals:

🧵

www.biorxiv.org/content/10.6...
January 8, 2026 at 1:56 PM
Next is our own Vangelis Vassos talking about the implementation of polygenic scores in psychiatry, and whether we are ready yet
January 8, 2026 at 1:55 PM
I'm in the London Genetics Network annual meeting. First up is Sanjay Sisodiya, who is talking about genetic complexity in a monogenic epilepsy
January 8, 2026 at 1:06 PM
Reposted by Joni Coleman
After 5 years of data collection, our WARN-D machine learning competition to forecast depression onset is now LIVE! We hope many of you will participate—we have incredibly rich data.

If you share a single thing of my lab this year, please make it this competition.

eiko-fried.com/warn-d-machi...
WARN-D machine learning competition is live » Eiko Fried
If you share one single thing of our team in 2026—on social media or per email with your colleagues—please let it be this machine learning competition. It was half a decade of work to get here, especi...
eiko-fried.com
January 7, 2026 at 7:39 PM
Reposted by Joni Coleman
No, YOU'RE crying on the train into work...
xkcd.com/3172/
Fifteen Years
xkcd.com
November 25, 2025 at 9:35 AM
Reposted by Joni Coleman
Join us this evening to celebrate the achievements of our outstanding
award winners and enjoy an inspiring talk. #WCPG2025
October 23, 2025 at 12:04 PM
Reposted by Joni Coleman
The PRISMA team had a great time presenting our posters on Precision and Genomic Medicine in Psychiatry at the #WCPG2025 in Cancún! 🌴🧬 It was exciting to share our work, learn from others, and connect with colleagues from around the world. @danielmorenodeluca.bsky.social
October 22, 2025 at 7:14 PM
Reposted by Joni Coleman
A quick thread of some great Purdue representation sharing our amazing science at @ispg.bsky.social annual conference #WCPG2025! 🧬 🧠 🧪

First up: @ktnthompson.bsky.social presented work investigating whether family acceptance & belonging mitigate depression risk 👪
October 22, 2025 at 7:58 PM
Reposted by Joni Coleman
Join Dr. Cathryn Lewis for a deep dive into "Navigating the Genetics
of Depression: Academic Integrity, Culture, and Leadership" in the Grand Cenote, first floor, tomorrow morning at 8:30 AM EST. #WCPG2025
October 23, 2025 at 2:02 AM
Reposted by Joni Coleman
🚨 I’ll be joining Psychological Science as an Associate Editor starting next month. People at, or near, my intersection of psych genetics, clinical psych, psychological Epidemiology should consider the journal for your best work! (read the EiCs editorial on the journal policies/goals below)
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
October 22, 2025 at 1:06 PM
The Estonian Biobank is an awesome resource (and @klehto.bsky.social is similarly awesome) — a fantastic opportunity to do some great science!
🎉 Come to see @triinuvarvas.bsky.social poster nr W56 at #wcpg2025 today!

Also, we are recruiting in 2026 and if you are interested in PhD or postdoc positions to work with the fantastic Estonian Biobank data then get in touch or fill out the interest form here ➡️ genomics.ut.ee/en/research-...
October 22, 2025 at 5:21 PM
Reposted by Joni Coleman
This talk, in combination with the one from @laurahercher.bsky.social and the response from @toddlencz.bsky.social just triggered SO many conversations… many continued into the early hours of today, so many people were discussing at the post- session bar gathering at #WCPG2025 …hooray!
"Don't miss Dr. Peter Visscher's insightful talk on "Heritable Polygenic
Editing and Genomic Medicine: Frontier, Futile or Fiasco?". Join us and learn about the future
of genetics. #WCPG2025
October 22, 2025 at 2:26 PM
Reposted by Joni Coleman
An absolutely fantastic opening plenary for the day by @alexcharney.bsky.social …a masterclass in tenacity, vulnerability and courage. Standing ovation. 🥲
I am so proud of this community’s willingness and ability to have difficult but healthy conversations #WCPG2025
Dr. Alexander Charney will discuss why studying the living brain is
essential for understanding how it really works. Join us this morning
at 8:30 AM EST in the Grand Cenote, 1st Floor. #WCPG2025
October 22, 2025 at 3:34 PM