Susan Gregurick
@sgregurick.bsky.social
I’m the Associate Director for Data Science at the NIH. All views, posts, and retweets are my own.
www.nature.com/articles/s41...
🧪. Very cool
🧪. Very cool
A filamentary soft robotic probe for multimodal in utero monitoring of fetal health - Nature Biomedical Engineering
A soft robotic probe enables continuous in utero monitoring of fetal physiological parameters, including heart rate, blood oxygen saturation, temperature and electrocardiogram data, during open or fet...
www.nature.com
January 27, 2026 at 11:28 AM
www.nature.com/articles/s41...
🧪. Very cool
🧪. Very cool
Temperature‐Dependent Chain Structures during Solution‐Grown Crystallization via Atomic Force Microscopy - Wang - Macromolecular Rapid Communications - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
🧪. Neat study of crystallization and polymer chain folding.
🧪. Neat study of crystallization and polymer chain folding.
Temperature‐Dependent Chain Structures during Solution‐Grown Crystallization via Atomic Force Microscopy
AFM-based single-molecule force spectroscopy was employed to investigate temperature-dependent single-chain folding structures of semi-crystalline PEO. Force–volume measurements enabled correlation o...
onlinelibrary.wiley.com
January 27, 2026 at 11:19 AM
Temperature‐Dependent Chain Structures during Solution‐Grown Crystallization via Atomic Force Microscopy - Wang - Macromolecular Rapid Communications - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
🧪. Neat study of crystallization and polymer chain folding.
🧪. Neat study of crystallization and polymer chain folding.
SAIGE-GPU — Accelerating Genome- and Phenome-Wide Association Studies using GPUs url: academic.oup.com/bioinformati... 🧪 really good news for biomedical researchers using NIH STRIDES clouds.
SAIGE-GPU — Accelerating Genome- and Phenome-Wide Association Studies using GPUs
AbstractMotivation. Genome-wide association studies (GWAS) at biobank scale are computationally intensive, especially for admixed populations requiring rob
academic.oup.com
January 23, 2026 at 11:27 AM
SAIGE-GPU — Accelerating Genome- and Phenome-Wide Association Studies using GPUs url: academic.oup.com/bioinformati... 🧪 really good news for biomedical researchers using NIH STRIDES clouds.
www.nature.com/articles/s41.... Awesome work
Holistic evaluation of large language models for medical tasks with MedHELM - Nature Medicine
MedHELM, an extensible evaluation framework including a new taxonomy for classifying medical tasks and a benchmark of many datasets across these categories, enables the evaluation of large language mo...
www.nature.com
January 21, 2026 at 11:14 AM
www.nature.com/articles/s41.... Awesome work
Mental Disorders as a Risk Factor of Acute Coronary Syndrome url: jamanetwork.com/journals/jam.... 🧪 interesting meta analysis indicates PTSD and sleep disorders emerged as significant risk factors for ACS
Mental Disorders as a Risk Factor of Acute Coronary Syndrome
This systematic review and meta-analysis investigates the association between mental disorders and acute coronary syndrome.
jamanetwork.com
January 15, 2026 at 2:43 PM
Mental Disorders as a Risk Factor of Acute Coronary Syndrome url: jamanetwork.com/journals/jam.... 🧪 interesting meta analysis indicates PTSD and sleep disorders emerged as significant risk factors for ACS
Reposted by Susan Gregurick
Immune cell response to spinal cord injury in a zebrafish larva. Credit to @beckergroup.bsky.social. #ZebrafishZunday 🧪
January 11, 2026 at 10:32 AM
Immune cell response to spinal cord injury in a zebrafish larva. Credit to @beckergroup.bsky.social. #ZebrafishZunday 🧪
academic.oup.com/bib/article/.... 🧪. Work illustrates knowledge graphs gene–gene interactions within oligogenic combinations. Very thoughtful study.
Benchmarking knowledge graph embedding models for the prediction of oligogenic combinations
Abstract. Identifying the potential oligogenic causes of rare diseases remains a challenge, notwithstanding the advancements made in the last decade. While
academic.oup.com
January 11, 2026 at 12:27 PM
academic.oup.com/bib/article/.... 🧪. Work illustrates knowledge graphs gene–gene interactions within oligogenic combinations. Very thoughtful study.
Uncovering regional atrophy not explained by tau deposition using Additional Pathology Inference (AddiPath) - Binding - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/10.1002/... 🧪
Uncovering regional atrophy not explained by tau deposition using Additional Pathology Inference (AddiPath)
Background Mixed pathology is prevalent in Alzheimer's disease (AD) but difficult to detect in vivo as biomarkers for several additional pathologies are in their infancy. Cortical thickness (CT) atr...
alz-journals.onlinelibrary.wiley.com
January 10, 2026 at 11:43 AM
Uncovering regional atrophy not explained by tau deposition using Additional Pathology Inference (AddiPath) - Binding - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/10.1002/... 🧪
www.nature.com/articles/s41.... This is exciting illustrating feasibility of remote biomarker assessment using capillary blood, obtained by fingerstick collection
A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology - Nature Medicine
This multicenter study demonstrates use of dried and capillary blood as a minimally invasive, scalable approach for Alzheimer’s biomarker testing in research, with potential as a widely scalable popul...
www.nature.com
January 7, 2026 at 11:30 AM
www.nature.com/articles/s41.... This is exciting illustrating feasibility of remote biomarker assessment using capillary blood, obtained by fingerstick collection
pubs.acs.org
January 6, 2026 at 11:21 AM
academic.oup.com/nargab/artic.... Neat. Authors integrate disease-association information from DisGeNET and tissue-specific gene expression data from GTEx to identify key tissues involved in complex diseases.
DEDUCE: statistical inference on disease-associated genes uncovers tissue–disease associations
Abstract. Accurate identification of affected tissues of human diseases is important for the derivation of disease etiology and the development of new trea
academic.oup.com
January 2, 2026 at 11:58 AM
academic.oup.com/nargab/artic.... Neat. Authors integrate disease-association information from DisGeNET and tissue-specific gene expression data from GTEx to identify key tissues involved in complex diseases.
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doi.org/10.1111/acel.... The paper from the October 22nd, 2025 Brain Aging Symposium is out!
doi.org/10.1111/acel.... The paper from the October 22nd, 2025 Brain Aging Symposium is out!
The Right Person, the Right Treatment, at the Right Time in Alzheimer's Disease: Insights From the 2025 Brain Aging Symposium
The Brain Aging Symposium highlighted how early detection and longitudinal tracking, enabled by multimodal biomarker integration, reveal critical roles for lipid metabolism, sex differences, and popu...
doi.org
December 30, 2025 at 1:00 PM
🧪
doi.org/10.1111/acel.... The paper from the October 22nd, 2025 Brain Aging Symposium is out!
doi.org/10.1111/acel.... The paper from the October 22nd, 2025 Brain Aging Symposium is out!
Informative Co‐Data Learning for High‐Dimensional Horseshoe Regression - Busatto - 2026 - Biometrical Journal - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
Informative Co‐Data Learning for High‐Dimensional Horseshoe Regression
High-dimensional data often arise from clinical genomics research to infer relevant predictors of a particular trait. A way to improve the predictive performance is by incorporating information about...
onlinelibrary.wiley.com
December 30, 2025 at 12:55 PM
Informative Co‐Data Learning for High‐Dimensional Horseshoe Regression - Busatto - 2026 - Biometrical Journal - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
www.nature.com/articles/s41.... Interesting article 🧪
Context matching is not reasoning when performing generalized clinical evaluation of generative language models - npj Digital Medicine
npj Digital Medicine - Context matching is not reasoning when performing generalized clinical evaluation of generative language models
www.nature.com
December 28, 2025 at 2:01 PM
www.nature.com/articles/s41.... Interesting article 🧪
🧪
www.nature.com/articles/s43.... Exciting multimodal LO-VLM that learns from both images and descriptions written by experts to enable analysis optical coherence tomography scans.
www.nature.com
December 28, 2025 at 1:56 PM
🧪
www.nature.com/articles/s43.... Exciting multimodal LO-VLM that learns from both images and descriptions written by experts to enable analysis optical coherence tomography scans.
www.nature.com
December 28, 2025 at 1:56 PM
www.nature.com/articles/s43.... Exciting multimodal LO-VLM that learns from both images and descriptions written by experts to enable analysis optical coherence tomography scans.
Integrating Event‐Based and Network Diffusion Models to Predict Individual Tau Progression in Alzheimer's Disease - Sandell - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/10.1002/.... 🧪. Neat article
alz-journals.onlinelibrary.wiley.com
December 28, 2025 at 1:38 PM
Integrating Event‐Based and Network Diffusion Models to Predict Individual Tau Progression in Alzheimer's Disease - Sandell - 2025 - Alzheimer's & Dementia - Wiley Online Library alz-journals.onlinelibrary.wiley.com/doi/10.1002/.... 🧪. Neat article
www.nature.com/articles/s41.... Preliminary study illustrates potential of GPT models in accurately detecting subtle linguistic markers indicative of SLDs, such as echolalia, pronoun reversal, and atypical pragmatic language usage.
Exploiting large language models for diagnosing autism associated language disorders and identifying distinct features - npj Digital Medicine
npj Digital Medicine - Exploiting large language models for diagnosing autism associated language disorders and identifying distinct features
www.nature.com
December 17, 2025 at 11:27 AM
www.nature.com/articles/s41.... Preliminary study illustrates potential of GPT models in accurately detecting subtle linguistic markers indicative of SLDs, such as echolalia, pronoun reversal, and atypical pragmatic language usage.
isevjournals.onlinelibrary.wiley.com/doi/10.1002/.... New work by AstraZeneca on hybrid Extracellular vesicles. Very cool.
Hybrid Extracellular Vesicles for Efficient Loading and Functional Delivery of mRNA
Hybrid extracellular vesicles (HEV) produced by EV-LNP fusion enable efficient loading and functional delivery of mRNA. HEV integrated properties of both EV and LNP contributing to their excellent ce...
isevjournals.onlinelibrary.wiley.com
December 16, 2025 at 11:12 AM
isevjournals.onlinelibrary.wiley.com/doi/10.1002/.... New work by AstraZeneca on hybrid Extracellular vesicles. Very cool.
Reposted by Susan Gregurick
What underlies the dynamics of #RedBloodCell production? Nicola Wilson explores a @plosbiology.org study that suggests a broadly applicable mechanism able to balance the maintenance of the steady-state with an effective stress response 🧪 #erythropoiesis Paper: plos.io/3KDskbX Primer: plos.io/4j4QBV1
December 15, 2025 at 9:05 AM
What underlies the dynamics of #RedBloodCell production? Nicola Wilson explores a @plosbiology.org study that suggests a broadly applicable mechanism able to balance the maintenance of the steady-state with an effective stress response 🧪 #erythropoiesis Paper: plos.io/3KDskbX Primer: plos.io/4j4QBV1
onlinelibrary.wiley.com/doi/10.1002/... 🧪. polarization-entangled photon pairs can analyze monolayer cells and distinguish between two types of cell layers
Probing polarization response of monolayer cell cultures with entangled photon pairs
Innovative optical detection using polarization and quantum techniques is presented for biological sample analysis. This method utilizes non-classical light, specifically entangled photon pairs, for ...
onlinelibrary.wiley.com
December 15, 2025 at 11:51 AM
onlinelibrary.wiley.com/doi/10.1002/... 🧪. polarization-entangled photon pairs can analyze monolayer cells and distinguish between two types of cell layers
link.springer.com/article/10.1.... 🧪. Neat study to check if grass could serve as effective bioindicators for detecting changes in As and Se soil contamination profiles and provide an evaluation of three technologies used for evaluating plant health.
Grass is a tattletale: using grass as a biomonitoring tool for remote sensing of coal combustion residue contamination - Environmental Monitoring and Assessment
Coal-fired power plants generate coal combustion residuals (CCRs), which are typically disposed of in landfills and surface impoundments that must be monitored to ensure that hazardous constituents su...
link.springer.com
December 10, 2025 at 9:06 AM
link.springer.com/article/10.1.... 🧪. Neat study to check if grass could serve as effective bioindicators for detecting changes in As and Se soil contamination profiles and provide an evaluation of three technologies used for evaluating plant health.