Jamie Walker, MD, PhD
@jmewalker.bsky.social
Neuropathologist at Mount Sinai NYC | research interests: healthy aging, #resistance and #resilience against #Alzheimer's pathology, spatial proteomics, hippocampi | other interests: tennis, nature, hiking, rock climbing |
Reposted by Jamie Walker, MD, PhD
Patient can’t look up or down. What’s going on?
December 31, 2024 at 4:35 PM
Patient can’t look up or down. What’s going on?
AD, PART and CTE share the same 3R/4R-tau+ NFTs, but in a different distribution … what about their proteomes? Excited to share our spatial proteomics study comparing #Alzheimers, #PART and #CTE hippocampi doi.org/10.1002/alz....
#neuropath #neuroscience #neurology #proteomics
#neuropath #neuroscience #neurology #proteomics
Spatial proteomic differences in chronic traumatic encephalopathy, Alzheimer's disease, and primary age‐related tauopathy hippocampi
INTRODUCTION Alzheimer's disease (AD), primary age-related tauopathy (PART), and chronic traumatic encephalopathy (CTE) all feature hyperphosphorylated tau (p-tau)–immunoreactive neurofibrillary deg...
doi.org
December 31, 2024 at 2:21 PM
AD, PART and CTE share the same 3R/4R-tau+ NFTs, but in a different distribution … what about their proteomes? Excited to share our spatial proteomics study comparing #Alzheimers, #PART and #CTE hippocampi doi.org/10.1002/alz....
#neuropath #neuroscience #neurology #proteomics
#neuropath #neuroscience #neurology #proteomics
This is a spinal cord anterior horn motor neuron … do you see what 👁️see? #neuropath #neuroskyence
December 17, 2024 at 8:35 PM
This is a spinal cord anterior horn motor neuron … do you see what 👁️see? #neuropath #neuroskyence
Reposted by Jamie Walker, MD, PhD
Brains of Alzheimer's patients—but look at the other aggregated proteins! We explore how two distinct variants of αSynuclein co-pathology contribute to hippocampal degeneration. Check out our new article in @braincomms.bsky.social: academic.oup.com/braincomms/a... 🧠🧪
December 14, 2024 at 9:47 AM
Brains of Alzheimer's patients—but look at the other aggregated proteins! We explore how two distinct variants of αSynuclein co-pathology contribute to hippocampal degeneration. Check out our new article in @braincomms.bsky.social: academic.oup.com/braincomms/a... 🧠🧪
Here’s a pineal gland, named after the pine cone! Did you know Descartes thought the pineal was the seat of the soul? www.neurology.org/doi/10.1212/...
The brain is cut in the axial plane here. What other structures can you identify? Happy Holidays! #neuroskyence #neuropath #neurology #neuroanatomy
The brain is cut in the axial plane here. What other structures can you identify? Happy Holidays! #neuroskyence #neuropath #neurology #neuroanatomy
December 13, 2024 at 12:05 AM
Here’s a pineal gland, named after the pine cone! Did you know Descartes thought the pineal was the seat of the soul? www.neurology.org/doi/10.1212/...
The brain is cut in the axial plane here. What other structures can you identify? Happy Holidays! #neuroskyence #neuropath #neurology #neuroanatomy
The brain is cut in the axial plane here. What other structures can you identify? Happy Holidays! #neuroskyence #neuropath #neurology #neuroanatomy
Reposted by Jamie Walker, MD, PhD
I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...
Method of the Year 2024: spatial proteomics - Nature Methods
Approaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in health and disease.
www.nature.com
December 6, 2024 at 8:52 PM
I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...
Got some new cookie cutters … the heart and the coronal section! Can you guess any of the diagnoses? #neuropath #neuroscience #neuroskyence
November 22, 2024 at 6:55 PM
Got some new cookie cutters … the heart and the coronal section! Can you guess any of the diagnoses? #neuropath #neuroscience #neuroskyence
Reposted by Jamie Walker, MD, PhD
Fantastic explanation of the anatomy of the human #Hippocampus! Great video and visualizations!👌 #neuroscience #PsychSciSky vimeo.com/323365182
Morphology of Memory: The Anatomy of the Human Hippocampus
The hippocampus is a part of the brain known to be critical for learning and memory. It is made up of many interconnected regions with distinct characteristics.…
vimeo.com
November 17, 2024 at 3:00 PM
Fantastic explanation of the anatomy of the human #Hippocampus! Great video and visualizations!👌 #neuroscience #PsychSciSky vimeo.com/323365182
Check out this cool #hippocampus with what appears to be hippocampal sclerosis. #neuropath
November 14, 2024 at 12:50 PM
Check out this cool #hippocampus with what appears to be hippocampal sclerosis. #neuropath