José L. McFaline-Figueroa
@jlmcfalinefigueroa.bsky.social
Assistant Professor, BME, Columbia University
Reposted by José L. McFaline-Figueroa
October newsletter is out. Watch the latest Faces of IICD interview, read about the latest breast cancer research highlights and the GROW conference, and more.
cancerdynamics.columbia.edu/news/iicd-ne...
#BreastCancerAwareness @nygenome.org @elhamazizi.bsky.social @jlmcfalinefigueroa.bsky.social
cancerdynamics.columbia.edu/news/iicd-ne...
#BreastCancerAwareness @nygenome.org @elhamazizi.bsky.social @jlmcfalinefigueroa.bsky.social
October 6, 2025 at 1:17 PM
October newsletter is out. Watch the latest Faces of IICD interview, read about the latest breast cancer research highlights and the GROW conference, and more.
cancerdynamics.columbia.edu/news/iicd-ne...
#BreastCancerAwareness @nygenome.org @elhamazizi.bsky.social @jlmcfalinefigueroa.bsky.social
cancerdynamics.columbia.edu/news/iicd-ne...
#BreastCancerAwareness @nygenome.org @elhamazizi.bsky.social @jlmcfalinefigueroa.bsky.social
We’re hiring!📣
Exciting opportunity at the Irving Institute for Cancer Dynamics and School of Engineering and Applied Science at Columbia: Associate Research Scientist. Lead pooled CRISPR + Perturb-seq screens to close AI-identified knowledge gaps. Apply apply.interfolio.com/172825
Exciting opportunity at the Irving Institute for Cancer Dynamics and School of Engineering and Applied Science at Columbia: Associate Research Scientist. Lead pooled CRISPR + Perturb-seq screens to close AI-identified knowledge gaps. Apply apply.interfolio.com/172825
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
September 29, 2025 at 10:32 PM
We’re hiring!📣
Exciting opportunity at the Irving Institute for Cancer Dynamics and School of Engineering and Applied Science at Columbia: Associate Research Scientist. Lead pooled CRISPR + Perturb-seq screens to close AI-identified knowledge gaps. Apply apply.interfolio.com/172825
Exciting opportunity at the Irving Institute for Cancer Dynamics and School of Engineering and Applied Science at Columbia: Associate Research Scientist. Lead pooled CRISPR + Perturb-seq screens to close AI-identified knowledge gaps. Apply apply.interfolio.com/172825
Please share!
The Irving Institute for Cancer Dynamics and the Fu Foundation School of Engineering & Applied Science at Columbia are seeking an Associate Research Scientist to design & execute pooled CRISPR and Perturb-seq screens. Apply here: apply.interfolio.com/172825
The Irving Institute for Cancer Dynamics and the Fu Foundation School of Engineering & Applied Science at Columbia are seeking an Associate Research Scientist to design & execute pooled CRISPR and Perturb-seq screens. Apply here: apply.interfolio.com/172825
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
September 16, 2025 at 3:02 PM
Please share!
The Irving Institute for Cancer Dynamics and the Fu Foundation School of Engineering & Applied Science at Columbia are seeking an Associate Research Scientist to design & execute pooled CRISPR and Perturb-seq screens. Apply here: apply.interfolio.com/172825
The Irving Institute for Cancer Dynamics and the Fu Foundation School of Engineering & Applied Science at Columbia are seeking an Associate Research Scientist to design & execute pooled CRISPR and Perturb-seq screens. Apply here: apply.interfolio.com/172825
Reposted by José L. McFaline-Figueroa
To all post-docs: The Genome Biology dept @embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Group Leader - Genome Biology Unit
Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...
embl.wd103.myworkdayjobs.com
July 30, 2025 at 1:41 PM
To all post-docs: The Genome Biology dept @embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Wondeful collaboration! This study with the Shah lab (Columbia Chemistry), led by Anne Vlimmeren and Ross Giglio, profiled disease associated SHP2 variants, linking variant-specific changes in molecular programs with differences in structure and substrate specificity. Check it out!
Check out our latest preprint, from Anne van Vlimmeren in my group and Ross Giglio in @jlmcfalinefigueroa.bsky.social's lab. We used single-cell transcriptomics, biochemistry, and structural analysis, to reveal how mechanistically distinct SHP2 disease mutations yield different cellular states.
Multiplexed single-cell transcriptomics reveals diverse phenotypic outcomes for pathogenic SHP2 variants https://www.biorxiv.org/content/10.1101/2025.06.30.662374v1
July 10, 2025 at 4:51 PM
Wondeful collaboration! This study with the Shah lab (Columbia Chemistry), led by Anne Vlimmeren and Ross Giglio, profiled disease associated SHP2 variants, linking variant-specific changes in molecular programs with differences in structure and substrate specificity. Check it out!
Reposted by José L. McFaline-Figueroa
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
February 8, 2025 at 9:21 PM
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
Reposted by José L. McFaline-Figueroa
I wonder if spreading extremely encouraging experimental results on helping treat pancreatic cancer with *gasp* mRNA vaccines may help people who have villainized them come around. This is a good press release on the study and links to the Nature paper. www.mskcc.org/news/can-mrn...
In Early-Phase Pancreatic Cancer Clinical Trial, Investigational mRNA Vaccine Induces Sustained Immune Activity in Small Patient Group
Learn how MSK researchers are deploying mRNA vaccines against pancreatic cancer.
www.mskcc.org
February 28, 2025 at 5:02 PM
I wonder if spreading extremely encouraging experimental results on helping treat pancreatic cancer with *gasp* mRNA vaccines may help people who have villainized them come around. This is a good press release on the study and links to the Nature paper. www.mskcc.org/news/can-mrn...
Reposted by José L. McFaline-Figueroa
Of the 4000 researchers at NIH, only 20% are tenured. They’re going to fire all the rest as their contracts come up for renewal, absolutely decimating research at the NIH. This is catastrophic, not just for Americans, but for the whole world.
www.science.org/content/arti...
www.science.org/content/arti...
NIH ban on renewing senior scientists adds to assaults on its in-house research
Policy follows firings of tenure-track scientists and suspension of training programs
www.science.org
February 28, 2025 at 6:19 AM
Of the 4000 researchers at NIH, only 20% are tenured. They’re going to fire all the rest as their contracts come up for renewal, absolutely decimating research at the NIH. This is catastrophic, not just for Americans, but for the whole world.
www.science.org/content/arti...
www.science.org/content/arti...