Johannes Larsch
@jlarsch.bsky.social
Assistant Prof. at the University of Lausanne. Interested in how brains control social behavior.
https://www.unil.ch/cig/en/home/menuinst/research/prof-larsch.html
https://www.unil.ch/cig/en/home/menuinst/research/prof-larsch.html
Reposted by Johannes Larsch
November 2, 2025 at 8:14 AM
Reposted by Johannes Larsch
Having personally sworn for years that insects don’t use GPCRs for odour detection, Suguru Takagi (@sugurutakagi.bsky.social) discovers that, in fact, they sometimes do …
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A GPCR signaling pathway in insect odor detection
Odor detection differs fundamentally in vertebrates, which use G protein-coupled receptors (GPCRs), and insects, which employ ion channels. Here, we report the first evidence for a GPCR defining tunin...
www.biorxiv.org
October 6, 2025 at 4:17 AM
Having personally sworn for years that insects don’t use GPCRs for odour detection, Suguru Takagi (@sugurutakagi.bsky.social) discovers that, in fact, they sometimes do …
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Johannes Larsch
“Blame your parents if you can’t pay enough attention." At least when you are a zebrafish! Our new study on attentional switching together with Kumaresh Krishnan, @paulapflitsch.bsky.social , @zwitscherarmin.bsky.social and Florian Engert is out in Science Advances:
doi.org/10.1126/scia...
doi.org/10.1126/scia...
October 3, 2025 at 9:23 PM
“Blame your parents if you can’t pay enough attention." At least when you are a zebrafish! Our new study on attentional switching together with Kumaresh Krishnan, @paulapflitsch.bsky.social , @zwitscherarmin.bsky.social and Florian Engert is out in Science Advances:
doi.org/10.1126/scia...
doi.org/10.1126/scia...
Reposted by Johannes Larsch
The final version of our paper on how ants and possibly other insects use a crazy mechanism involving extensive transcriptional interference to regulate odorant receptor expression is now open access in my favorite journal, @currentbiology.bsky.social
authors.elsevier.com/sd/article/S...
authors.elsevier.com/sd/article/S...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
September 19, 2025 at 3:44 PM
The final version of our paper on how ants and possibly other insects use a crazy mechanism involving extensive transcriptional interference to regulate odorant receptor expression is now open access in my favorite journal, @currentbiology.bsky.social
authors.elsevier.com/sd/article/S...
authors.elsevier.com/sd/article/S...
Reposted by Johannes Larsch
Apply now for FBM #PhD #Fellowships in #Life #Sciences – join one of the Faculty’s leading laboratories.
🚨 Application deadline for fellowships: October 6, 2025.
➡️ www.unil.ch/news/en/1756...
@unil.bsky.social @dmf-unil.bsky.social @dee-unil.bsky.social @dib-unil.bsky.social #fbm #unil
🚨 Application deadline for fellowships: October 6, 2025.
➡️ www.unil.ch/news/en/1756...
@unil.bsky.social @dmf-unil.bsky.social @dee-unil.bsky.social @dib-unil.bsky.social #fbm #unil
PhD Fellowships in Life Sciences: a competition open to future doctoral students.
Apply now for FBM PhD Fellowships in Life Sciences – join one of the Faculty’s leading laboratories.
www.unil.ch
September 18, 2025 at 8:38 AM
Apply now for FBM #PhD #Fellowships in #Life #Sciences – join one of the Faculty’s leading laboratories.
🚨 Application deadline for fellowships: October 6, 2025.
➡️ www.unil.ch/news/en/1756...
@unil.bsky.social @dmf-unil.bsky.social @dee-unil.bsky.social @dib-unil.bsky.social #fbm #unil
🚨 Application deadline for fellowships: October 6, 2025.
➡️ www.unil.ch/news/en/1756...
@unil.bsky.social @dmf-unil.bsky.social @dee-unil.bsky.social @dib-unil.bsky.social #fbm #unil
Reposted by Johannes Larsch
Check out this exciting study led by Anh-Tuan Trinh from our lab, where we investigated how thalamocortical-like circuits in the zebrafish pallium receive, represent, and integrate sensory information:
🔗 doi.org/10.1101/2025...
🔗 doi.org/10.1101/2025...
Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain
Thalamocortical projections contribute to the spatial organization and functional hierarchies of the mammalian cortex. Primary sensory cortices receive topographically segregated information from firs...
doi.org
September 16, 2025 at 12:54 PM
Check out this exciting study led by Anh-Tuan Trinh from our lab, where we investigated how thalamocortical-like circuits in the zebrafish pallium receive, represent, and integrate sensory information:
🔗 doi.org/10.1101/2025...
🔗 doi.org/10.1101/2025...
Reposted by Johannes Larsch
BonnBrain 2026 is a go!
March 23–25, Bonn (DZNE, Bonn, Germany).
Apply now: www.bonnbrain.de
Limited slots. Presentations (posters/talks) selected from submitted abstracts.
Keynotes & invited speakers 👇
March 23–25, Bonn (DZNE, Bonn, Germany).
Apply now: www.bonnbrain.de
Limited slots. Presentations (posters/talks) selected from submitted abstracts.
Keynotes & invited speakers 👇
September 9, 2025 at 9:45 AM
BonnBrain 2026 is a go!
March 23–25, Bonn (DZNE, Bonn, Germany).
Apply now: www.bonnbrain.de
Limited slots. Presentations (posters/talks) selected from submitted abstracts.
Keynotes & invited speakers 👇
March 23–25, Bonn (DZNE, Bonn, Germany).
Apply now: www.bonnbrain.de
Limited slots. Presentations (posters/talks) selected from submitted abstracts.
Keynotes & invited speakers 👇
Reposted by Johannes Larsch
Now published @natecoevo.nature.com with @annika-nichols.bsky.social, our latest on the evolution of 𝘴𝘭𝘦𝘦𝘱 across 𝟲𝟬 𝘀𝗽𝗲𝗰𝗶𝗲𝘀 of cichlid fishes! doi.org/10.1038/s415...
with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social
with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social
August 28, 2025 at 2:18 PM
Now published @natecoevo.nature.com with @annika-nichols.bsky.social, our latest on the evolution of 𝘴𝘭𝘦𝘦𝘱 across 𝟲𝟬 𝘀𝗽𝗲𝗰𝗶𝗲𝘀 of cichlid fishes! doi.org/10.1038/s415...
with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social
with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social
Jim was an incredibly gifted teacher. Still remember his fundamentals in Neuroscience. Also, great, dry sense of humor.
A. James Hudpseth, who died 16 August at age 79, devoted his 50-year career to untangling how the ear converts sound into electrical signals.
By @callimcflurry.bsky.social
www.thetransmitter.org/hearing/reme...
By @callimcflurry.bsky.social
www.thetransmitter.org/hearing/reme...
Remembering A. James Hudspeth, hair cell explorer
Hudspeth, who died 16 August at age 79, devoted his 50-year career to untangling how the ear converts sound into electrical signals.
www.thetransmitter.org
August 23, 2025 at 3:14 PM
Jim was an incredibly gifted teacher. Still remember his fundamentals in Neuroscience. Also, great, dry sense of humor.
Reposted by Johannes Larsch
Latest from the lab. Beautiful work from Joanna Lau and a fantastic collaboration with James Fitzgerald.
www.cell.com/current-biol...
www.cell.com/current-biol...
Supraspinal commands have a modular organization that is behavioral context specific
Lau et al. use calcium imaging and statistical modeling to comprehensively survey
reticulospinal activity during diverse locomotor behaviors. They find that a small
set of functional modules act combi...
www.cell.com
August 23, 2025 at 12:48 PM
Latest from the lab. Beautiful work from Joanna Lau and a fantastic collaboration with James Fitzgerald.
www.cell.com/current-biol...
www.cell.com/current-biol...
Reposted by Johannes Larsch
Can't wait to read this preprint from Misha Ahrens and team. Calcium imaging in larval zebrafish, in every cell in the body! Amazing.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 22, 2025 at 10:21 PM
Can't wait to read this preprint from Misha Ahrens and team. Calcium imaging in larval zebrafish, in every cell in the body! Amazing.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Johannes Larsch
If you’re interested in ants, olfaction, gene regulation, or all of the above, here’s a new preprint from the lab for you. It describes an unorthodox mechanism of transcriptional interference by which ant olfactory sensory neurons produce a single functional receptor.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Transcriptional Interference Gates Monogenic Odorant Receptor Expression in Ants
Communication is crucial to social life, and in ants, it is mediated primarily through olfaction. Ants have more odorant receptor (OR) genes than any other group of insects, generated through tandem d...
www.biorxiv.org
August 21, 2025 at 9:31 PM
If you’re interested in ants, olfaction, gene regulation, or all of the above, here’s a new preprint from the lab for you. It describes an unorthodox mechanism of transcriptional interference by which ant olfactory sensory neurons produce a single functional receptor.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Johannes Larsch
Neuronal diversity is written in transcriptional codes 🧬. But what is the logic of these codes that define cell types and wiring patterns?
To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠
#preprint thread ⬇️1/8
To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠
#preprint thread ⬇️1/8
August 21, 2025 at 4:04 PM
Neuronal diversity is written in transcriptional codes 🧬. But what is the logic of these codes that define cell types and wiring patterns?
To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠
#preprint thread ⬇️1/8
To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠
#preprint thread ⬇️1/8
Reposted by Johannes Larsch
1. "'Trusting the experts is not a feature of either a science or democracy," Kennedy said."
It's literally a vital feature of both science and of representative democracy.
I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.
It's literally a vital feature of both science and of representative democracy.
I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.
RFK Jr. in interview with Scripps News: ‘Trusting the experts is not science’
HHS Secretary RFK Jr. sat down with Scripps News for a wide-ranging interview, discussing mRNA vaccine funding policy changes and a recent shooting at the Centers for Disease Control and Prevention.
www.scrippsnews.com
August 12, 2025 at 4:48 AM
1. "'Trusting the experts is not a feature of either a science or democracy," Kennedy said."
It's literally a vital feature of both science and of representative democracy.
I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.
It's literally a vital feature of both science and of representative democracy.
I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.
Reposted by Johannes Larsch
💡 Whether you’re a new student, a lab leader or a decision-maker at an institutional level, you can now find free tools and guidance all in one place on our new Learning Resources page.
With everything in the thread below and more, get learning today!
buff.ly/sIpX5gU
With everything in the thread below and more, get learning today!
buff.ly/sIpX5gU
August 8, 2025 at 5:24 PM
💡 Whether you’re a new student, a lab leader or a decision-maker at an institutional level, you can now find free tools and guidance all in one place on our new Learning Resources page.
With everything in the thread below and more, get learning today!
buff.ly/sIpX5gU
With everything in the thread below and more, get learning today!
buff.ly/sIpX5gU
Reposted by Johannes Larsch
Latest from my lab: we identify and characterize the function of binocular neurons zebrafish larvae use to hunt prey; sciencedirect.com/science/arti.... Congrats to Richard Tian, Gewei Yan and Tommy Lam @tkclam.bsky.social!
Binocular integration of prey stimuli in the zebrafish visual system
Most animals with two eyes combine the inputs to achieve binocular vision, which can serve numerous functions and is particularly useful in hunting pr…
sciencedirect.com
June 27, 2025 at 2:38 PM
Latest from my lab: we identify and characterize the function of binocular neurons zebrafish larvae use to hunt prey; sciencedirect.com/science/arti.... Congrats to Richard Tian, Gewei Yan and Tommy Lam @tkclam.bsky.social!
Reposted by Johannes Larsch
How does the brain work in natural scenarios, in multi-animal societies of wild animals? 🧠 🧪 🦇
doi.org/10.1126/scie...
(1/n)
doi.org/10.1126/scie...
(1/n)
January 30, 2025 at 7:20 PM
How does the brain work in natural scenarios, in multi-animal societies of wild animals? 🧠 🧪 🦇
doi.org/10.1126/scie...
(1/n)
doi.org/10.1126/scie...
(1/n)
Reposted by Johannes Larsch
🚨Very happy that my PhD work is now out in @nature.com!
We discovered that evolution, by acting in the midbrain, shifted the threshold to escape in Peromyscus mice, to fine-tune defensive strategies in different environments
www.nature.com/articles/s41...
This was a truly collaborative effort! 🧵⬇️
We discovered that evolution, by acting in the midbrain, shifted the threshold to escape in Peromyscus mice, to fine-tune defensive strategies in different environments
www.nature.com/articles/s41...
This was a truly collaborative effort! 🧵⬇️
July 23, 2025 at 3:06 PM
🚨Very happy that my PhD work is now out in @nature.com!
We discovered that evolution, by acting in the midbrain, shifted the threshold to escape in Peromyscus mice, to fine-tune defensive strategies in different environments
www.nature.com/articles/s41...
This was a truly collaborative effort! 🧵⬇️
We discovered that evolution, by acting in the midbrain, shifted the threshold to escape in Peromyscus mice, to fine-tune defensive strategies in different environments
www.nature.com/articles/s41...
This was a truly collaborative effort! 🧵⬇️
Reposted by Johannes Larsch
Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland unil.ch/cig/en/home....
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...
June 16, 2025 at 4:18 PM
Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland unil.ch/cig/en/home....
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...
Become our colleague! Tenure-track Assistant Professor position at The Center for Integrative Genomics, University of Lausanne, Switzerland. unil.ch/cig/en/home....
More details for how to apply are here:
www.nature.com/naturecareer...
More details for how to apply are here:
www.nature.com/naturecareer...
July 21, 2025 at 10:18 AM
Become our colleague! Tenure-track Assistant Professor position at The Center for Integrative Genomics, University of Lausanne, Switzerland. unil.ch/cig/en/home....
More details for how to apply are here:
www.nature.com/naturecareer...
More details for how to apply are here:
www.nature.com/naturecareer...
Reposted by Johannes Larsch
We are looking for a new neuroscience colleague at the tenure track assistant professor level! All details below! 🧠🔥 All details here: www.epfl.ch/about/workin...
Faculty Position in Neuroscience
The School of Life Sciences at EPFL invites applications for a Tenure Track Assistant Professor position in Neuroscience. At EPFL researchers develop and apply innovative technologies to understand br...
www.epfl.ch
July 21, 2025 at 10:05 AM
We are looking for a new neuroscience colleague at the tenure track assistant professor level! All details below! 🧠🔥 All details here: www.epfl.ch/about/workin...
Reposted by Johannes Larsch
Congrats to @stednitz.bsky.social and Andrew Lesak on their @currentbiology.bsky.social paper! They use HMM to identify two interaction states in #zebrafish: one visual for long-range interactions and one lateral line for quick, close interactions.
Free link: authors.elsevier.com/a/1lCYh3QW8S...
Free link: authors.elsevier.com/a/1lCYh3QW8S...
June 4, 2025 at 3:14 AM
Congrats to @stednitz.bsky.social and Andrew Lesak on their @currentbiology.bsky.social paper! They use HMM to identify two interaction states in #zebrafish: one visual for long-range interactions and one lateral line for quick, close interactions.
Free link: authors.elsevier.com/a/1lCYh3QW8S...
Free link: authors.elsevier.com/a/1lCYh3QW8S...
Reposted by Johannes Larsch
Heart disease is the world’s leading killer, and tackling it demands decoding the multi-gene networks driving disease progression 🫀
Learn how researchers used Medaka fish plus high-throughput heartbeat imaging to build a biomarker toolkit for early screening.
www.nature.com/articles/s41...
Learn how researchers used Medaka fish plus high-throughput heartbeat imaging to build a biomarker toolkit for early screening.
www.nature.com/articles/s41...
May 13, 2025 at 9:40 AM
Heart disease is the world’s leading killer, and tackling it demands decoding the multi-gene networks driving disease progression 🫀
Learn how researchers used Medaka fish plus high-throughput heartbeat imaging to build a biomarker toolkit for early screening.
www.nature.com/articles/s41...
Learn how researchers used Medaka fish plus high-throughput heartbeat imaging to build a biomarker toolkit for early screening.
www.nature.com/articles/s41...
Reposted by Johannes Larsch
We are proud to present our new preprint “Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish”, just posted on bioRxiv (www.biorxiv.org/content/10.1...). (1/10)
Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish
Accumulating information is a critical component of most circuit computations in the brain across species, yet its precise implementation at the synaptic level remains poorly understood. Dissecting su...
www.biorxiv.org
March 17, 2025 at 10:12 AM
We are proud to present our new preprint “Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish”, just posted on bioRxiv (www.biorxiv.org/content/10.1...). (1/10)