Jesse Brown
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jesseab.bsky.social
Jesse Brown
@jesseab.bsky.social
Neuro + data scientist, building radiata.ai - better brain biomarkers.
Reposted by Jesse Brown
❤️ Bluesky fMRI people! 3-day #fMRI course live online Jan 7-9, 2026.

#SPM, #ICA, GLM, connectivity, mediation, MRI physics, #DataScience with @vcalhoun.bsky.social and Kent Kiehl.

We love talking methods & connecting with colleagues! Come join us!

Register here:
sites.google.com/dartmouth.ed...
fMRI Course
Instructors
sites.google.com
November 14, 2025 at 6:04 PM
Reposted by Jesse Brown
A couple of computational neuroscience positions at UT Dallas. This is an emerging program with great collaboration potential.

jobs.utdallas.edu/postings/30394
Open Rank faculty positions in Computational Neuroscience
Position Description The Department of Neuroscience at The University of Texas at Dallas seeks to hire up to two tenure-system faculty members (open rank) with expertise in neural coding, neural compu...
jobs.utdallas.edu
October 21, 2025 at 2:37 PM
Reposted by Jesse Brown
Why do brain networks vary? Do these differences shape behavior? If every 🧠 is unique, how can we detect common features of brain organization?
@rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print):
go.illinois.edu/Gratton2025-...

#neuroskyence #psychscisky #MedSky
🧵👇
Dense Phenotyping of Human Brain Network Organization Using Precision fMRI
The advent of noninvasive imaging methods like functional magnetic resonance imaging (fMRI) transformed cognitive neuroscience, providing insights into large-scale brain networks and their link to cog...
go.illinois.edu
October 16, 2025 at 3:00 PM
Reposted by Jesse Brown
Network spreading and local biological vulnerability in amyotrophic lateral sclerosis |
doi.org/10.1038/s420...

How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️
September 16, 2025 at 4:17 PM
Stimulating the LGN with ultrasound and real-time fMRI, this is cool.

Ultrasound system for precise neuromodulation of human deep brain circuits.
www.nature.com/articles/s41...
September 15, 2025 at 9:17 PM
Reposted by Jesse Brown
The Dept. of Psychology at the U. Wisconsin–Madison has an opening for an Assistant Professor in the area of Computational Neuroscience and/or Cognitive Science, with an emphasis on artificial intelligence (AI).

Domain of behavior or cognition is open. Details at jobs.wisc.edu/jobs/assista...
Assistant Professor of Psychology - Madison, Wisconsin, United States
Current Employees: If you are currently employed at any of the Universities of Wisconsin, log in to Workday to apply through the internal application process.Job Category:FacultyEmployment Type:Regula...
jobs.wisc.edu
September 9, 2025 at 9:08 PM
Would be perfectly happy if cool new mechanistic brain function studies like this one omitted the individual trait prediction. Don't think every new finding needs a cognitive correlation to have merit.
www.nature.com/articles/s41...
Large-scale cortical functional networks are organized in structured cycles - Nature Neuroscience
The human brain cycles through a repertoire of brain networks on a 1-second timescale during rest and tasks. This cycling appears to allow periodic engagement of essential cognitive functions, with th...
www.nature.com
September 8, 2025 at 7:16 PM
Reposted by Jesse Brown
Sad day for peope who still believe brain areas are the primary organizational units of function in the brain.

www.nature.com/articles/s41...
A brain-wide map of neural activity during complex behaviour - Nature
The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task i...
www.nature.com
September 4, 2025 at 11:17 AM
Doing a deep dive on TMS. Kinda crazy how much of this field is built on DLPFC-sgACC anticorrelation. One little edge.
August 13, 2025 at 8:08 PM
Reposted by Jesse Brown
When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...
The history and future of resting-state functional magnetic resonance imaging - Nature
This Review provides an overview of the history of resting-state functional MRI research, which has helped to reveal the spatiotemporal organization of the brain, and discusses how it can contribute f...
www.nature.com
May 28, 2025 at 3:52 PM
Reposted by Jesse Brown
Using the advances in the science of aging to prevent the major age-related diseases (no reversal of aging required) www.theguardian.com/world/2025/m... @theguardian.com
‘Get rid of the pseudoscience’: top doctor’s plan to improve America’s health
Eric Topol says we can prevent age-related disease and live fuller lives – but only if we reject anti-science ‘malarkey’
www.theguardian.com
May 8, 2025 at 12:54 PM
Reposted by Jesse Brown
🔴 Our `Brain and AI` team at Meta has a new Research Engineer position in Paris to work on infrastructure and scale deep learning experimentations:

www.metacareers.com/jobs/1769841...

We'll favor industry experience or Github track record.
www.metacareers.com
May 1, 2025 at 6:47 PM
Reposted by Jesse Brown
The scientific community needs to develop processes to support, hire and retain researchers whose work sits between traditional fields of study, writes @avramholmes.bsky.social

#neuroskyence

www.thetransmitter.org/future-of-fm...
fMRI must break out of its silo
We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.
www.thetransmitter.org
April 16, 2025 at 3:29 PM
Reposted by Jesse Brown
Most people haven’t heard of this test, which is available in the US. It accurately predicts Alzheimer’s (not just if there’s a risk, but when). It is modulated by exercise and likely other lifestyle factors.
Here’s (almost) everything we know about it
erictopol.substack.com/p/the-breakt...
April 14, 2025 at 1:48 PM
Reposted by Jesse Brown
It's shocking how little is known about the brainstem red nucleus. In our new paper “The human brainstem’s red nucleus was upgraded to support goal-directed action” out now in @naturecomms.bsky.social we show that current thinking on the red nucleus is in need of a serious upgrade. rdcu.be/ehbOy
April 10, 2025 at 3:46 PM
Reposted by Jesse Brown
Happy to share that our article “Human lifespan changes in the brain’s functional connectome” is now published online at Nature Neuroscience @natureneuro.bsky.social !

Many thanks to all collaborators & data contributors, and the editor team & reviewers!

www.nature.com/articles/s41...
Human lifespan changes in the brain’s functional connectome - Nature Neuroscience
Sun et al. report human lifespan changes in the brain’s functional connectome in 33,250 individuals, which highlights critical growth milestones and distinct maturation patterns and offers a normative...
www.nature.com
April 4, 2025 at 5:48 AM
Reposted by Jesse Brown
We are HIRING!! Postdoc for multimodal imaging lab at Yale. If you get excited about preclinical and prodromal states, atypical Alzheimer’s, graph theory, predictive modeling, and/or baked goods at lab meetings, come join us: postdocs.yale.edu/postdoctoral...

Please share with your circles!
March 28, 2025 at 5:26 PM
Proxies aren't the thing, the thing is the thing. Just don't forget what the "thing" is.
March 31, 2025 at 9:13 PM
Reposted by Jesse Brown
Is generalized epilepsy a seizure of the whole brain or a specific brain network?

In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome.

Paper: nature.com/articles/s41...

A 🧵 below:
A generalized epilepsy network derived from brain abnormalities and deep brain stimulation - Nature Communications
Ji et al. identify an idiopathic generalised epilepsy network that links heterogeneously distributed brain abnormalities to a common brain network and deep brain stimulation sites which reduce general...
nature.com
March 24, 2025 at 4:01 PM
Here's a new open dataset of ~4000 processed brain structural MRIs from across the lifespan:
huggingface.co/datasets/rad...

Get it in three lines of code:
pip install datasets
from datasets import load_dataset
ds = load_dataset("radiata-ai/brain-structure", trust_remote_code=True)
radiata-ai/brain-structure · Datasets at Hugging Face
We’re on a journey to advance and democratize artificial intelligence through open source and open science.
huggingface.co
January 21, 2025 at 7:03 PM
Reposted by Jesse Brown
Rethinking Brain Mechanisms in the Light of Evolution with Paul Cisek youtu.be/CnT7jaQX4X8?... - if you want to understand what brains are for (and their functional organisation), this is the way... 👍👏
Rethinking Brain Mechanisms in the Light of Evolution with Paul Cisek
YouTube video by Kempner Institute at Harvard University
youtu.be
January 18, 2025 at 12:26 PM
Reposted by Jesse Brown
Using a brain–computer interface to challenge monkeys to override their natural time courses of neural activity reveals that the time courses are highly robust, suggestive of network-level computational mechanisms

@aaronbatista.bsky.social and colleagues

www.nature.com/articles/s41...
Dynamical constraints on neural population activity - Nature Neuroscience
Oby, Degenhart, Grigsby and colleagues used a brain–computer interface to challenge monkeys to override their natural time courses of neural activity. They found the time courses to be highly robust, ...
www.nature.com
January 17, 2025 at 3:38 PM
Here's how you can build classifiers for brain structural MRI data on radiata.ai.

www.youtube.com/watch?v=oDan...

We built this to make it easier to:
- set up and run machine learning models on the fly with no installs
Radiata Brain Imaging Classification
YouTube video by Radiata
www.youtube.com
January 7, 2025 at 6:31 PM