Jeff Bush
@jeffbush.bsky.social
Developmental geneticist who studies the cellular basis of mammalian morphogenesis and how it goes wrong in congenital disease.
Super interesting study identifying gene responsible for heart defects in Down syndrome www.nature.com/articles/s41...
Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21 - Nature
Studies using human pluripotent stem cells and a mouse model of Down syndrome identify HMGN1 as a key contributor to congenital heart defects in individuals with Down syndrome.
www.nature.com
October 29, 2025 at 4:20 PM
Super interesting study identifying gene responsible for heart defects in Down syndrome www.nature.com/articles/s41...
Congratulations Sarah and team! @knoxstar.bsky.social @ucsfdentistry.bsky.social
August 26, 2025 at 11:58 PM
Congratulations Sarah and team! @knoxstar.bsky.social @ucsfdentistry.bsky.social
Nice! Congratulations Jeremy, Roman, Andrei, and everyone!
New work from stellar scientists Jeremy Williams and Roman Camarda. Many contributors including the amazing Zena Werb and Atul Butte
Work explores how breast cancer cells interact directly with adipocytes via gap junctions, leading to lipid release.
@ctbatucsf.bsky.social @ucsfcancer.bsky.social
Work explores how breast cancer cells interact directly with adipocytes via gap junctions, leading to lipid release.
@ctbatucsf.bsky.social @ucsfcancer.bsky.social
Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis
Nature Communications - Breast cancer cells interact with neighbouring adipocytes, but the mechanisms are not fully understood. Here, the authors show that triple-negative breast cancer (TNBC)...
www.nature.com
August 20, 2025 at 11:42 PM
Nice! Congratulations Jeremy, Roman, Andrei, and everyone!
Nice going Lily and Erica!@drericabiophd.bsky.social @ctbatucsf.bsky.social @ucsfdentistry.bsky.social
#DBfeature 🐣
CRISPR-Cas13d enables targeted gene expression knockdown in chick embryos, expanding the experimental potential and versatility of this model system.
by Minyoung Kim and Erica Hutchins @drericabiophd.bsky.social
www.sciencedirect.com/science/arti...
#CRISPRCas #ChickEmbryo
CRISPR-Cas13d enables targeted gene expression knockdown in chick embryos, expanding the experimental potential and versatility of this model system.
by Minyoung Kim and Erica Hutchins @drericabiophd.bsky.social
www.sciencedirect.com/science/arti...
#CRISPRCas #ChickEmbryo
August 13, 2025 at 3:43 PM
Nice going Lily and Erica!@drericabiophd.bsky.social @ctbatucsf.bsky.social @ucsfdentistry.bsky.social
Reposted by Jeff Bush
Karin Shamardani, DDS/PhD candidate, is working with Jeff Bush @jeffbush.bsky.social to study how Efnb1 and the understudied actin-regulator gene Shrm4 interact to control palatal outgrowth and mesenchymal organization during craniofacial development.
August 5, 2025 at 6:46 PM
Karin Shamardani, DDS/PhD candidate, is working with Jeff Bush @jeffbush.bsky.social to study how Efnb1 and the understudied actin-regulator gene Shrm4 interact to control palatal outgrowth and mesenchymal organization during craniofacial development.
Reposted by Jeff Bush
I'm thrilled to announce that my lab is opening this August in the Department of Cell & Tissue Biology @ UCSF!
We will study airway stem cells and explore how they generate multiciliated cells (my favorite!) to keep pathogens and debris out of the lung. Check out choksilab.org for more!
We will study airway stem cells and explore how they generate multiciliated cells (my favorite!) to keep pathogens and debris out of the lung. Check out choksilab.org for more!
June 5, 2025 at 2:30 PM
I'm thrilled to announce that my lab is opening this August in the Department of Cell & Tissue Biology @ UCSF!
We will study airway stem cells and explore how they generate multiciliated cells (my favorite!) to keep pathogens and debris out of the lung. Check out choksilab.org for more!
We will study airway stem cells and explore how they generate multiciliated cells (my favorite!) to keep pathogens and debris out of the lung. Check out choksilab.org for more!
Reposted by Jeff Bush
CTB welcomes new Assistant Professor Semil Choksi @semilc.bsky.social to the department! The Choksi Lab will study how airway stem cells generate multiciliated cells - and how this process goes wrong in respiratory disease. His lab is opening this August. Visit choksilab.org to learn more!
June 5, 2025 at 11:07 PM
CTB welcomes new Assistant Professor Semil Choksi @semilc.bsky.social to the department! The Choksi Lab will study how airway stem cells generate multiciliated cells - and how this process goes wrong in respiratory disease. His lab is opening this August. Visit choksilab.org to learn more!
Just recruited two more grad students to be appreciated on Bluesky! @jasminegarciia.bsky.social @davidsungtooth.bsky.social @ophirklein.bsky.social
April 1, 2025 at 8:31 PM
Just recruited two more grad students to be appreciated on Bluesky! @jasminegarciia.bsky.social @davidsungtooth.bsky.social @ophirklein.bsky.social
Happy graduate student appreciation week to David Sung and Luke Lucido!…also trying to encourage them to join Bluesky
April 1, 2025 at 8:18 PM
Happy graduate student appreciation week to David Sung and Luke Lucido!…also trying to encourage them to join Bluesky
Congratulations to Camilla Teng, for winning the "Platform presentation SDB prize" for post-docs at the Northwest SDB meeting, which sounds like it was a fantastic meeting! Camilla will be on the faculty job market soon, so look out for her! @socdevbio.bsky.social @ctbatucsf.bsky.social
March 28, 2025 at 4:32 PM
Congratulations to Camilla Teng, for winning the "Platform presentation SDB prize" for post-docs at the Northwest SDB meeting, which sounds like it was a fantastic meeting! Camilla will be on the faculty job market soon, so look out for her! @socdevbio.bsky.social @ctbatucsf.bsky.social
I'm thrilled to share that CTB faculty Fred Chang has been elected as a AAAS fellow! Congratulations to Fred on this well-deserved honor. @fredchanglab.bsky.social @ctbatucsf.bsky.social
www.ucsf.edu/news/2025/03/429681/ucsfs-fred-chang-honored-election-aaas
www.ucsf.edu/news/2025/03/429681/ucsfs-fred-chang-honored-election-aaas
UCSF’s Fred Chang Is Honored with Election to AAAS
Cell biologist Fred Chang, MD, PhD, has been named a fellow in the American Association for the Advancement of Science (AAAS), a highly esteemed lifetime honor within the scientific community.
www.ucsf.edu
March 28, 2025 at 3:26 PM
I'm thrilled to share that CTB faculty Fred Chang has been elected as a AAAS fellow! Congratulations to Fred on this well-deserved honor. @fredchanglab.bsky.social @ctbatucsf.bsky.social
www.ucsf.edu/news/2025/03/429681/ucsfs-fred-chang-honored-election-aaas
www.ucsf.edu/news/2025/03/429681/ucsfs-fred-chang-honored-election-aaas
Reposted by Jeff Bush
A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb.
https://go.nature.com/41a7Zzj
https://go.nature.com/41a7Zzj
Rare genetic disorder treated in womb for the first time
The child, who is now almost three years old, shows no signs of the often fatal motor neuron disease.
go.nature.com
February 20, 2025 at 11:17 AM
A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb.
https://go.nature.com/41a7Zzj
https://go.nature.com/41a7Zzj
Reposted by Jeff Bush
To my friends and colleagues at UAB, IU, UF, FSU, UL, WashU, OSU, CWRU, etc, etc. Call both your senators and your representative. They listen. Emphasize the direct economic impact of NIH research, and the indirect impacts on pharmaceutical/biotech. Underscore its relevance to national security.
The Senate HELP Committee has jurisdiction over NIH.
GOP members of the committee represent AK, AL, IN, FL, KS, KY, LA, ME, MO, OH, and SC.
Research universities and hospitals in those states need to be extra loud.
GOP members of the committee represent AK, AL, IN, FL, KS, KY, LA, ME, MO, OH, and SC.
Research universities and hospitals in those states need to be extra loud.
February 8, 2025 at 3:27 AM
To my friends and colleagues at UAB, IU, UF, FSU, UL, WashU, OSU, CWRU, etc, etc. Call both your senators and your representative. They listen. Emphasize the direct economic impact of NIH research, and the indirect impacts on pharmaceutical/biotech. Underscore its relevance to national security.
Great new lab opening!…
The Zwick lab has landed in the Regenerative Medicine Institute @NYU! I’m incredibly excited to build a team to study how epithelial organs are patterned and remodeled throughout life, with a major focus on the remarkable changes that occur in the maternal body during pregnancy..1/5
February 6, 2025 at 6:50 PM
Great new lab opening!…
Reposted by Jeff Bush
Vahid Niknezhad joined the Knox lab in 2022 as a postdoctoral scholar, focusing on the development of biomaterials and hydrogels for drug delivery systems and tissue repair technologies. #ucsfNPAW #UCSFpostdocs
September 16, 2024 at 11:28 PM
Vahid Niknezhad joined the Knox lab in 2022 as a postdoctoral scholar, focusing on the development of biomaterials and hydrogels for drug delivery systems and tissue repair technologies. #ucsfNPAW #UCSFpostdocs
Reposted by Jeff Bush
Helen, a postdoc in the Hutchins lab @drericabiophd.bsky.social, is interested in how RNA binding proteins and modifications contribute to the dynamic process of neural crest cell development, and is also passionate about laboratory waste reduction and scientific illustration.#ucsfNPAW #UCSFpostdocs
September 16, 2024 at 11:31 PM
Helen, a postdoc in the Hutchins lab @drericabiophd.bsky.social, is interested in how RNA binding proteins and modifications contribute to the dynamic process of neural crest cell development, and is also passionate about laboratory waste reduction and scientific illustration.#ucsfNPAW #UCSFpostdocs
Reposted by Jeff Bush
Petria-George Thompson, a postdoc in the Goga lab @andreigoga.bsky.social, is studying mechanisms of CDK2 inhibition as therapeutics for breast cancer and other cancers. #ucsfNPAW #UCSFpostdocs
September 16, 2024 at 11:35 PM
Petria-George Thompson, a postdoc in the Goga lab @andreigoga.bsky.social, is studying mechanisms of CDK2 inhibition as therapeutics for breast cancer and other cancers. #ucsfNPAW #UCSFpostdocs
Reposted by Jeff Bush
Check her out at UCSF postdoc slam!
postdocs.ucsf.edu/news/introdu...
postdocs.ucsf.edu/news/introdu...
Introducing the 2024 Postdoc Slam Finalists!
Meet the 10 postdocs who will give 3-minute talks at our popular annual research communications competition on Sept. 18. The event will be a lively centerpiece to our National Postdoc Appreciation Wee...
postdocs.ucsf.edu
September 16, 2024 at 11:53 PM
Check her out at UCSF postdoc slam!
postdocs.ucsf.edu/news/introdu...
postdocs.ucsf.edu/news/introdu...
Reposted by Jeff Bush
Camilla Teng in the Bush lab @jeffbushman.bsky.social is working to understand cell behaviors and force generators driving development of the upper lip. This mysterious process has relevance to cleft lip, which is the most common congenital anomaly affecting the face. #ucsfNPAW #UCSFpostdocs
September 16, 2024 at 11:37 PM
Camilla Teng in the Bush lab @jeffbushman.bsky.social is working to understand cell behaviors and force generators driving development of the upper lip. This mysterious process has relevance to cleft lip, which is the most common congenital anomaly affecting the face. #ucsfNPAW #UCSFpostdocs