Jan Haaker
@janhaaker.bsky.social
Social learning
Neuropharmacology
@Isnlab.bsky.social
Alumnus @jungeakademie.bsky.social
Neuropharmacology
@Isnlab.bsky.social
Alumnus @jungeakademie.bsky.social
Pinned
Jan Haaker
@janhaaker.bsky.social
· Oct 22
Resolving temporal threat uncertainty by observational learning involves the amygdala, hippocampus and anterior insula
While the neurobiological distinction between temporally predictable (cued) and unpredictable (contextual) threats has been well-characterized in direct learning using the NPU paradigm, it is poorly u...
www.biorxiv.org
Can we learn about unpredictable threats via observation of others? Yes, temporally predictable and unpredictable threats are learned by distinct contributions of the amygdala and hippocampus.
ALSO: We find higher activation in the amygdala and anterior insula to others' pain that serves learning.
ALSO: We find higher activation in the amygdala and anterior insula to others' pain that serves learning.
Reposted by Jan Haaker
Paying Open Access for your own paper
January 17, 2026 at 8:08 AM
Paying Open Access for your own paper
Reposted by Jan Haaker
Currently reviewing some new "In a nutshell" videos for our @sfb-trr-289.bsky.social YouTube channel! 🤩
Some cool videos coming up feat. @janhaaker.bsky.social, @jlaferton.bsky.social and Christine Knaevelsrud! 🤯
For now, stay tuned and subscribe: youtube.com/@sfb-trr_289...
Some cool videos coming up feat. @janhaaker.bsky.social, @jlaferton.bsky.social and Christine Knaevelsrud! 🤯
For now, stay tuned and subscribe: youtube.com/@sfb-trr_289...
January 13, 2026 at 4:12 PM
Currently reviewing some new "In a nutshell" videos for our @sfb-trr-289.bsky.social YouTube channel! 🤩
Some cool videos coming up feat. @janhaaker.bsky.social, @jlaferton.bsky.social and Christine Knaevelsrud! 🤯
For now, stay tuned and subscribe: youtube.com/@sfb-trr_289...
Some cool videos coming up feat. @janhaaker.bsky.social, @jlaferton.bsky.social and Christine Knaevelsrud! 🤯
For now, stay tuned and subscribe: youtube.com/@sfb-trr_289...
Reposted by Jan Haaker
In genau einer Woche findet unser nächstes Kolloquium statt! Am 16.1. um 12 Uhr nimmt uns @helenahartmann.com mit in die Welt von "Science and Fiction - WissKomm mit fiktionalen Kurzgeschichten".
Nähere Infos und die Anmeldung findet ihr im Bild.
Wir freuen uns auf euch!
@scienceandfiction.net
Nähere Infos und die Anmeldung findet ihr im Bild.
Wir freuen uns auf euch!
@scienceandfiction.net
January 9, 2026 at 9:57 AM
In genau einer Woche findet unser nächstes Kolloquium statt! Am 16.1. um 12 Uhr nimmt uns @helenahartmann.com mit in die Welt von "Science and Fiction - WissKomm mit fiktionalen Kurzgeschichten".
Nähere Infos und die Anmeldung findet ihr im Bild.
Wir freuen uns auf euch!
@scienceandfiction.net
Nähere Infos und die Anmeldung findet ihr im Bild.
Wir freuen uns auf euch!
@scienceandfiction.net
Reposted by Jan Haaker
This paper had a pretty shocking headline result (40% of voxels!), so I dug into it, and I think it is wrong. Essentially: they compare two noisy measures and find that about 40% of voxels have different sign between the two. I think this is just noise!
Would love to hear expert views on this paper. It appears to show that the operationalization of brain activity the field has relied on for 3 decades—the BOLD response—is not actually a sensible measure of brain activity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
BOLD signal changes can oppose oxygen metabolism across the human cortex - Nature Neuroscience
Using quantitative brain imaging, the authors show opposite fMRI BOLD signal to metabolic activity due to variable oxygen extraction across the human cortex. This questions the canonical interpretatio...
www.nature.com
January 5, 2026 at 5:22 PM
This paper had a pretty shocking headline result (40% of voxels!), so I dug into it, and I think it is wrong. Essentially: they compare two noisy measures and find that about 40% of voxels have different sign between the two. I think this is just noise!
Reposted by Jan Haaker
fMRI signals “up,” but neural metabolism might be going “down.”
In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes.
rdcu.be/eUPO8
funds @erc.europa.eu
#neuroskyence 🧵:
In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes.
rdcu.be/eUPO8
funds @erc.europa.eu
#neuroskyence 🧵:
December 16, 2025 at 3:43 PM
fMRI signals “up,” but neural metabolism might be going “down.”
In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes.
rdcu.be/eUPO8
funds @erc.europa.eu
#neuroskyence 🧵:
In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes.
rdcu.be/eUPO8
funds @erc.europa.eu
#neuroskyence 🧵:
Reposted by Jan Haaker
How does cortisol tune brain networks to form strong emotional memories? Excited to share new work led by amazing former RA Flory Huang w collabs Rajita Sinha and @toddc.bsky.social #neuroskyence www.science.org/doi/10.1126/...
Dynamic brain mechanisms supporting salient memories under cortisol
The stress-related hormone cortisol alters dynamic brain networks predicting memory and arousal to promote emotional memories.
www.science.org
December 11, 2025 at 4:42 PM
How does cortisol tune brain networks to form strong emotional memories? Excited to share new work led by amazing former RA Flory Huang w collabs Rajita Sinha and @toddc.bsky.social #neuroskyence www.science.org/doi/10.1126/...
Reposted by Jan Haaker
The party drug MDMA (“ecstasy”) shows promising efficacy as adjunct to psychotherapy. The psychostimulant with entactogenic properties is known to induce arousal and euphoria. We now studied the neurochemistry underlying the behavioral effects of MDMA in rats lacking serotonin in the brain.
November 28, 2025 at 9:17 AM
The party drug MDMA (“ecstasy”) shows promising efficacy as adjunct to psychotherapy. The psychostimulant with entactogenic properties is known to induce arousal and euphoria. We now studied the neurochemistry underlying the behavioral effects of MDMA in rats lacking serotonin in the brain.
So cool to be included in this project showing that overgeneralization of threat responses learned by observation predicted higher anxiety symptoms in adolescents during wartime. All the credits go to Yoni Fishman and Tomer Shechner's Team
doi.org/10.1016/j.br...
doi.org/10.1016/j.br...
Redirecting
doi.org
December 3, 2025 at 7:36 PM
So cool to be included in this project showing that overgeneralization of threat responses learned by observation predicted higher anxiety symptoms in adolescents during wartime. All the credits go to Yoni Fishman and Tomer Shechner's Team
doi.org/10.1016/j.br...
doi.org/10.1016/j.br...
Reposted by Jan Haaker
😍 New work from A02! 😍
Marie Habermann and @christianbuchel.bsky.social from @isnlab.bsky.social found that controllability changes pain perception by increasing the precision of expectations! 👉⚡
Read it here: doi.org/10.1038/s414...
Marie Habermann and @christianbuchel.bsky.social from @isnlab.bsky.social found that controllability changes pain perception by increasing the precision of expectations! 👉⚡
Read it here: doi.org/10.1038/s414...
December 1, 2025 at 9:57 AM
😍 New work from A02! 😍
Marie Habermann and @christianbuchel.bsky.social from @isnlab.bsky.social found that controllability changes pain perception by increasing the precision of expectations! 👉⚡
Read it here: doi.org/10.1038/s414...
Marie Habermann and @christianbuchel.bsky.social from @isnlab.bsky.social found that controllability changes pain perception by increasing the precision of expectations! 👉⚡
Read it here: doi.org/10.1038/s414...
Reposted by Jan Haaker
New paper out on "Empathy and validation in chronic pain couples: a systematic review"
by Karolin Teichmüller et al.
journals.lww.com/painrpts/ful...
@anrei.bsky.social @uni-wuerzburg.de @tudresden.bsky.social @kanskelab.bsky.social
by Karolin Teichmüller et al.
journals.lww.com/painrpts/ful...
@anrei.bsky.social @uni-wuerzburg.de @tudresden.bsky.social @kanskelab.bsky.social
journals.lww.com
November 27, 2025 at 5:46 PM
New paper out on "Empathy and validation in chronic pain couples: a systematic review"
by Karolin Teichmüller et al.
journals.lww.com/painrpts/ful...
@anrei.bsky.social @uni-wuerzburg.de @tudresden.bsky.social @kanskelab.bsky.social
by Karolin Teichmüller et al.
journals.lww.com/painrpts/ful...
@anrei.bsky.social @uni-wuerzburg.de @tudresden.bsky.social @kanskelab.bsky.social
Reposted by Jan Haaker
👏 Congratulations to @uni-hamburg.de for being rated Germanys most sustainable university. Glad to see that UHH has been committed to lead by example in this important area over the past years.
www.uni-hamburg.de/en/newsroom/...
www.uni-hamburg.de/en/newsroom/...
The University of Hamburg Still Germany’s Most Sustainable University
www.uni-hamburg.de
November 26, 2025 at 8:52 PM
👏 Congratulations to @uni-hamburg.de for being rated Germanys most sustainable university. Glad to see that UHH has been committed to lead by example in this important area over the past years.
www.uni-hamburg.de/en/newsroom/...
www.uni-hamburg.de/en/newsroom/...
Reposted by Jan Haaker
Excited to share that the main work of my PhD has been published!
We found that having control over pain makes expectations more precise, and changes pain perception. This is accompanied by activation changes in the PAG, SMA and ACC.
You can read the full version of the paper here: rdcu.be/eQy6X
We found that having control over pain makes expectations more precise, and changes pain perception. This is accompanied by activation changes in the PAG, SMA and ACC.
You can read the full version of the paper here: rdcu.be/eQy6X
Controllability changes pain perception by increasing the precision of expectations
Nature Communications - Control over pain changes how intense it is perceived. Here, the authors show that this effect results from increased expectation precision with control, which changes...
rdcu.be
November 22, 2025 at 1:50 PM
Excited to share that the main work of my PhD has been published!
We found that having control over pain makes expectations more precise, and changes pain perception. This is accompanied by activation changes in the PAG, SMA and ACC.
You can read the full version of the paper here: rdcu.be/eQy6X
We found that having control over pain makes expectations more precise, and changes pain perception. This is accompanied by activation changes in the PAG, SMA and ACC.
You can read the full version of the paper here: rdcu.be/eQy6X
Reposted by Jan Haaker
We also have some new affiliated projects! 🤩
First, we heard a great talk from @jlaferton.bsky.social on enhancing treatment expectations for knee replacement outcomes🦵😷
Then, Marcel Wilhelm and Gertraud Gradl-Dietsch presented a project on the impact of different treatment framing on depression ☹️
First, we heard a great talk from @jlaferton.bsky.social on enhancing treatment expectations for knee replacement outcomes🦵😷
Then, Marcel Wilhelm and Gertraud Gradl-Dietsch presented a project on the impact of different treatment framing on depression ☹️
November 18, 2025 at 4:54 PM
We also have some new affiliated projects! 🤩
First, we heard a great talk from @jlaferton.bsky.social on enhancing treatment expectations for knee replacement outcomes🦵😷
Then, Marcel Wilhelm and Gertraud Gradl-Dietsch presented a project on the impact of different treatment framing on depression ☹️
First, we heard a great talk from @jlaferton.bsky.social on enhancing treatment expectations for knee replacement outcomes🦵😷
Then, Marcel Wilhelm and Gertraud Gradl-Dietsch presented a project on the impact of different treatment framing on depression ☹️
Reposted by Jan Haaker
Last up is @christianbuchel.bsky.social telling us about all things wrong with our current publishing system and how new models (for example @elife.bsky.social) are trying to break these barriers! 💪
Of course featuring this gem of a video by @glaucomflecken.bsky.social: youtu.be/ukAkG6c_N4M?...
Of course featuring this gem of a video by @glaucomflecken.bsky.social: youtu.be/ukAkG6c_N4M?...
November 18, 2025 at 5:16 PM
Last up is @christianbuchel.bsky.social telling us about all things wrong with our current publishing system and how new models (for example @elife.bsky.social) are trying to break these barriers! 💪
Of course featuring this gem of a video by @glaucomflecken.bsky.social: youtu.be/ukAkG6c_N4M?...
Of course featuring this gem of a video by @glaucomflecken.bsky.social: youtu.be/ukAkG6c_N4M?...
Reposted by Jan Haaker
Next up, @tobikube.bsky.social shows striking results of how positive vs. negative framing likelihoods of having a certain disease shapes the degree of people's concern about having this disease! 👩⚕️
November 19, 2025 at 8:39 AM
Next up, @tobikube.bsky.social shows striking results of how positive vs. negative framing likelihoods of having a certain disease shapes the degree of people's concern about having this disease! 👩⚕️
Starting the CRC „Treatment Expectation“ retreat. @sfb-trr-289.bsky.social
Exciting to present our project on variance processing in observational learning
Exciting to present our project on variance processing in observational learning
November 18, 2025 at 5:33 PM
Starting the CRC „Treatment Expectation“ retreat. @sfb-trr-289.bsky.social
Exciting to present our project on variance processing in observational learning
Exciting to present our project on variance processing in observational learning
Reposted by Jan Haaker
Our paper on improving statistical reporting in psychology is now online 🎉
As a part of this paper, we also created the Transparent Statistical Reporting in Psychology checklist, which researchers can use to improve their statistical reporting practices
www.nature.com/articles/s44...
As a part of this paper, we also created the Transparent Statistical Reporting in Psychology checklist, which researchers can use to improve their statistical reporting practices
www.nature.com/articles/s44...
November 14, 2025 at 8:43 PM
Our paper on improving statistical reporting in psychology is now online 🎉
As a part of this paper, we also created the Transparent Statistical Reporting in Psychology checklist, which researchers can use to improve their statistical reporting practices
www.nature.com/articles/s44...
As a part of this paper, we also created the Transparent Statistical Reporting in Psychology checklist, which researchers can use to improve their statistical reporting practices
www.nature.com/articles/s44...
Reposted by Jan Haaker
Tagging @isnlab.bsky.social @stefaniebrassen.bsky.social @helenblank.bsky.social @janhaaker.bsky.social @christianbuchel.bsky.social @aulenkamp.bsky.social @wohrlab.bsky.social @sheddenmora.bsky.social @rief01.bsky.social and all other CRC members! 😍
Starter pack: go.bsky.app/TgjkCXL
Starter pack: go.bsky.app/TgjkCXL
November 14, 2025 at 8:30 AM
Tagging @isnlab.bsky.social @stefaniebrassen.bsky.social @helenblank.bsky.social @janhaaker.bsky.social @christianbuchel.bsky.social @aulenkamp.bsky.social @wohrlab.bsky.social @sheddenmora.bsky.social @rief01.bsky.social and all other CRC members! 😍
Starter pack: go.bsky.app/TgjkCXL
Starter pack: go.bsky.app/TgjkCXL
Reposted by Jan Haaker
Another LBP story has reached the end: yesterday Laura Vercammen from Bram Vervliet’s lab successfully defended her PhD! Congrats, Laura! @tombeckers.bsky.social @lauraluyten.bsky.social
November 13, 2025 at 2:15 PM
Another LBP story has reached the end: yesterday Laura Vercammen from Bram Vervliet’s lab successfully defended her PhD! Congrats, Laura! @tombeckers.bsky.social @lauraluyten.bsky.social
Travelling back from beautiful Leuven after an excellent defense by Laura Vercammen on the reward processes in avoidance in rats.
Congratulations to her and the proud supervisors Bram Vervliet, @tombeckers.bsky.social and Laura Luyten.
And no, I am not travelling in that outfit
Congratulations to her and the proud supervisors Bram Vervliet, @tombeckers.bsky.social and Laura Luyten.
And no, I am not travelling in that outfit
November 13, 2025 at 10:46 AM
Travelling back from beautiful Leuven after an excellent defense by Laura Vercammen on the reward processes in avoidance in rats.
Congratulations to her and the proud supervisors Bram Vervliet, @tombeckers.bsky.social and Laura Luyten.
And no, I am not travelling in that outfit
Congratulations to her and the proud supervisors Bram Vervliet, @tombeckers.bsky.social and Laura Luyten.
And no, I am not travelling in that outfit
Reposted by Jan Haaker
🎥 New #SFB289 #webinar is uploaded on our YouTube channel! 🎥
Yesterday, Wiebke Ghandi from CINN at the University of Reading presented her work on targeting uncontrollable pain and answered the question: is there a role of the reward system?
(Re)watch it here: youtu.be/ck-1UyuoACk
Yesterday, Wiebke Ghandi from CINN at the University of Reading presented her work on targeting uncontrollable pain and answered the question: is there a role of the reward system?
(Re)watch it here: youtu.be/ck-1UyuoACk
Webinar: Wiebke Ghandi - Targeting uncontrollable pain: Is there a role for the reward system?
YouTube video by SFB-TRR 289 "Treatment Expectation"
youtu.be
November 12, 2025 at 9:59 AM
🎥 New #SFB289 #webinar is uploaded on our YouTube channel! 🎥
Yesterday, Wiebke Ghandi from CINN at the University of Reading presented her work on targeting uncontrollable pain and answered the question: is there a role of the reward system?
(Re)watch it here: youtu.be/ck-1UyuoACk
Yesterday, Wiebke Ghandi from CINN at the University of Reading presented her work on targeting uncontrollable pain and answered the question: is there a role of the reward system?
(Re)watch it here: youtu.be/ck-1UyuoACk
You are on a train to be on a thesis committee and your calendar says „labmeeting“
November 12, 2025 at 9:49 AM
You are on a train to be on a thesis committee and your calendar says „labmeeting“
Reposted by Jan Haaker
Bitte teilen und Werbung machen. Das ist das erste Lehrbuch dieser Art und relevant für ALLE, die im Gesundheitssystem arbeiten!
It was great to be a part of this little booklet - if you work in medicine, this one is for you!👩⚕️
We explain what placebo and nocebo effects are and how you can use them in your communication and work with patients! 🗣️
Shout-out to co-authors Lorenz Peters, @ulrikebingel.bsky.social & Sven Benson!
We explain what placebo and nocebo effects are and how you can use them in your communication and work with patients! 🗣️
Shout-out to co-authors Lorenz Peters, @ulrikebingel.bsky.social & Sven Benson!
⭐ Today we have something from our #scicomm (SC) project! ⭐
This new book is aimed at healthcare professionals and shows how the #placeboeffect and #treatmentexpectation can be used positively when dealing with patients. 👩⚕️👨⚕️
Read it here (physical copy/ebook) ➡️ link.springer.com/book/10.1007...
This new book is aimed at healthcare professionals and shows how the #placeboeffect and #treatmentexpectation can be used positively when dealing with patients. 👩⚕️👨⚕️
Read it here (physical copy/ebook) ➡️ link.springer.com/book/10.1007...
November 11, 2025 at 3:51 PM
Bitte teilen und Werbung machen. Das ist das erste Lehrbuch dieser Art und relevant für ALLE, die im Gesundheitssystem arbeiten!
Reposted by Jan Haaker
⭐ Today we have something from our #scicomm (SC) project! ⭐
This new book is aimed at healthcare professionals and shows how the #placeboeffect and #treatmentexpectation can be used positively when dealing with patients. 👩⚕️👨⚕️
Read it here (physical copy/ebook) ➡️ link.springer.com/book/10.1007...
This new book is aimed at healthcare professionals and shows how the #placeboeffect and #treatmentexpectation can be used positively when dealing with patients. 👩⚕️👨⚕️
Read it here (physical copy/ebook) ➡️ link.springer.com/book/10.1007...
November 4, 2025 at 10:23 AM
⭐ Today we have something from our #scicomm (SC) project! ⭐
This new book is aimed at healthcare professionals and shows how the #placeboeffect and #treatmentexpectation can be used positively when dealing with patients. 👩⚕️👨⚕️
Read it here (physical copy/ebook) ➡️ link.springer.com/book/10.1007...
This new book is aimed at healthcare professionals and shows how the #placeboeffect and #treatmentexpectation can be used positively when dealing with patients. 👩⚕️👨⚕️
Read it here (physical copy/ebook) ➡️ link.springer.com/book/10.1007...
Reposted by Jan Haaker
Join us for this talk by @janhaaker.bsky.social on "A functional view on how we respond to others’ pain: Empathy, threat learning and neuropeptides"
11 November, 1pm CET
tu-dresden.de/mn/psycholog...
11 November, 1pm CET
tu-dresden.de/mn/psycholog...
November 10, 2025 at 9:11 PM
Join us for this talk by @janhaaker.bsky.social on "A functional view on how we respond to others’ pain: Empathy, threat learning and neuropeptides"
11 November, 1pm CET
tu-dresden.de/mn/psycholog...
11 November, 1pm CET
tu-dresden.de/mn/psycholog...