Bhawik Jain
jainbhawik.bsky.social
Bhawik Jain
@jainbhawik.bsky.social
Cell and Molecular Biologist, Cricket enthusiast
Reposted by Bhawik Jain
🍨Interested in reading more about the study? Here is the N&Vs article written by Michael Salsaa & Gregory D. Fairn.
👉https://rdcu.be/eADFu
bit.ly/45zxHiL
Phosphoinositide flipping governs neomycin sensitivity - Nature Cell Biology
Neomycin toxicity in eukaryotic cells stems from its binding to phosphoinositides, primarily confined to the inner leaflet of the plasma membrane. New research reveals a complex lipid-trafficking path...
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August 13, 2025 at 8:05 PM
Reposted by Bhawik Jain
🍹 @grahamlab-vandy.bsky.social @jainbhawik.bsky.social & co report that the Neo1 P4-ATPase flips the #lipid PI4P across the #Golgi membrane to the cytosolic leaflet, preventing PI4P exposure and thereby conferring neomycin resistance.
bit.ly/45tauP7
P4-ATPases control phosphoinositide membrane asymmetry and neomycin resistance - Nature Cell Biology
Jain et al. report that the Neo1 P4-ATPase flips the lipid PI4P across the Golgi membrane to the cytosolic leaflet, preventing PI4P exposure and thereby conferring neomycin resistance.
bit.ly
August 13, 2025 at 8:05 PM
Excited to share our latest work published in @natcellbio.nature.com! We identify Neo1 as a novel phosphoinositide flippase that maintains membrane asymmetry and provides resistance to neomycin.@grahamlab-vandy.bsky.social. Check out the article and News & Views here
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rdcu.be/eweh9
P4-ATPases control phosphoinositide membrane asymmetry and neomycin resistance
Nature Cell Biology - Jain et al. report that the Neo1 P4-ATPase flips the lipid PI4P across the Golgi membrane to the cytosolic leaflet, preventing PI4P exposure and thereby conferring neomycin...
rdcu.be
July 14, 2025 at 7:28 PM
Reposted by Bhawik Jain
As April comes to a close, we wanted to share updates for the first quarter of 2025!!
April 30, 2025 at 1:43 AM