Iris Ka-Yi Chat
@iriskayichat.bsky.social
postdoc at ucla | clinical psych phd, temple | reward processing, psychoneuroimmunology, & mood psychopathology | she/they πππ°π±
Upregulation of reward mesolimbic activity and immune response to vaccination: a randomized controlled trial
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Upregulation of reward mesolimbic activity and immune response to vaccination: a randomized controlled trial - Nature Medicine
Upregulation of the ventral tegmental area via neurofeedback is associated with a stronger immune response to hepatitis B virus vaccination, and VTA upregulation is achieved through conscious positive...
www.nature.com
January 20, 2026 at 5:03 PM
Upregulation of reward mesolimbic activity and immune response to vaccination: a randomized controlled trial
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Thank you @acnporg.bsky.social for the ACNP Travel Award to make this opportunity happen, and Erika Forbes for nominating me for this award!
January 14, 2026 at 7:44 PM
Thank you @acnporg.bsky.social for the ACNP Travel Award to make this opportunity happen, and Erika Forbes for nominating me for this award!
At #ACNP2026? Come see my poster (W45, 5β7 pm)! We @erika-forbes.bsky.social find that immune activation and basal ganglia dopamine availability interact and relate to anhedonia among youth w/ depression, with evidence for anticipatory and not consummatory anhedonia.
Preprint is now available!
Preprint is now available!
Basal Ganglia Dopamine Availability and Immune Activation Interact and Relate to Anhedonia Severity among Youth with Depression
Anhedonia emerges in adolescence, has putative substrates in neural reward and dopamine systems, and is a hallmark of poor course in depression. Psychoneuroimmunology models suggest altered immune and...
www.biorxiv.org
January 14, 2026 at 7:38 PM
At #ACNP2026? Come see my poster (W45, 5β7 pm)! We @erika-forbes.bsky.social find that immune activation and basal ganglia dopamine availability interact and relate to anhedonia among youth w/ depression, with evidence for anticipatory and not consummatory anhedonia.
Preprint is now available!
Preprint is now available!
Reposted by Iris Ka-Yi Chat
This is your brain on Ritalin. Got your attention? Stimulant medications like Ritalin (methylphenidate) do, but not in the way you might think. They don't act directly on the brainβs attention systems! Find out what's really happening in @cellpress.bsky.social. doi.org/10.1016/j.ce...
December 24, 2025 at 4:46 PM
This is your brain on Ritalin. Got your attention? Stimulant medications like Ritalin (methylphenidate) do, but not in the way you might think. They don't act directly on the brainβs attention systems! Find out what's really happening in @cellpress.bsky.social. doi.org/10.1016/j.ce...
Reposted by Iris Ka-Yi Chat
Basal Ganglia Dopamine Availability and Immune Activation Interact and Relate to Anhedonia Severity among Youth with Depression https://www.biorxiv.org/content/10.64898/2025.12.23.696320v1
December 24, 2025 at 10:17 AM
Basal Ganglia Dopamine Availability and Immune Activation Interact and Relate to Anhedonia Severity among Youth with Depression https://www.biorxiv.org/content/10.64898/2025.12.23.696320v1
Reposted by Iris Ka-Yi Chat
The lab is recruiting a postdoc. Please share with anyone who might be interested.
www.adaptprogram.com/join-adapt
www.adaptprogram.com/join-adapt
Join the ADAPT Team β ADAPT
www.adaptprogram.com
December 11, 2025 at 4:21 PM
The lab is recruiting a postdoc. Please share with anyone who might be interested.
www.adaptprogram.com/join-adapt
www.adaptprogram.com/join-adapt
Reposted by Iris Ka-Yi Chat
Excited to share that I'm accepting applications for a PhD student to join my lab in Fall 2026!
More info on how to apply can be found here: graduate.catalog.tcu.edu/colleges/eng...
@bsamjournal.bsky.social @pnirs.bsky.social #HealthPsychology #PNI #Psychoneuroimmunology #DevelopmentalPsychology
More info on how to apply can be found here: graduate.catalog.tcu.edu/colleges/eng...
@bsamjournal.bsky.social @pnirs.bsky.social #HealthPsychology #PNI #Psychoneuroimmunology #DevelopmentalPsychology
December 11, 2025 at 12:55 AM
Excited to share that I'm accepting applications for a PhD student to join my lab in Fall 2026!
More info on how to apply can be found here: graduate.catalog.tcu.edu/colleges/eng...
@bsamjournal.bsky.social @pnirs.bsky.social #HealthPsychology #PNI #Psychoneuroimmunology #DevelopmentalPsychology
More info on how to apply can be found here: graduate.catalog.tcu.edu/colleges/eng...
@bsamjournal.bsky.social @pnirs.bsky.social #HealthPsychology #PNI #Psychoneuroimmunology #DevelopmentalPsychology
Reposted by Iris Ka-Yi Chat
The Two Faces of #PTSD: Fear vs. Emotional Pain. Our new research in Biological Psychiatry @biologicalpsych.bsky.social identifies distinct clinical & neural profiles.
AI says no one reads long papers, so we made an infographic!π
Full Paper (for the insistentsπ): doi.org/10.1016/j.bi...
AI says no one reads long papers, so we made an infographic!π
Full Paper (for the insistentsπ): doi.org/10.1016/j.bi...
December 6, 2025 at 11:35 AM
The Two Faces of #PTSD: Fear vs. Emotional Pain. Our new research in Biological Psychiatry @biologicalpsych.bsky.social identifies distinct clinical & neural profiles.
AI says no one reads long papers, so we made an infographic!π
Full Paper (for the insistentsπ): doi.org/10.1016/j.bi...
AI says no one reads long papers, so we made an infographic!π
Full Paper (for the insistentsπ): doi.org/10.1016/j.bi...
Reposted by Iris Ka-Yi Chat
Prevention and intervention for inflammation-associated transdiagnostic psychopathology: A role for clinical psychologists: https://osf.io/qysa2
December 4, 2025 at 9:20 AM
Prevention and intervention for inflammation-associated transdiagnostic psychopathology: A role for clinical psychologists: https://osf.io/qysa2
Reposted by Iris Ka-Yi Chat
Congratulations @iriskayichat.bsky.social!!! See you there π
Honored to receive the ACNP Travel Award and looking forward to attending my first ACNP conference in the Bahamas! #ACNP2026 @acnporg.bsky.social
What's the best part of Monday? π€
Getting to meet another group of fantastic @acnporg.bsky.social travel awardees π€©
..and don't forget to say hi to these all-stars at #ACNP2026
Getting to meet another group of fantastic @acnporg.bsky.social travel awardees π€©
..and don't forget to say hi to these all-stars at #ACNP2026
December 3, 2025 at 4:21 PM
Congratulations @iriskayichat.bsky.social!!! See you there π
Thanks, Kate π Looking forward to learning about your latest research at your coming talk. Letβs catch up!
December 3, 2025 at 3:22 PM
Thanks, Kate π Looking forward to learning about your latest research at your coming talk. Letβs catch up!
Thanks, Alex! π
December 3, 2025 at 3:17 PM
Thanks, Alex! π
Thanks, Steph! π
December 3, 2025 at 3:16 PM
Thanks, Steph! π
Honored to receive the ACNP Travel Award and looking forward to attending my first ACNP conference in the Bahamas! #ACNP2026 @acnporg.bsky.social
What's the best part of Monday? π€
Getting to meet another group of fantastic @acnporg.bsky.social travel awardees π€©
..and don't forget to say hi to these all-stars at #ACNP2026
Getting to meet another group of fantastic @acnporg.bsky.social travel awardees π€©
..and don't forget to say hi to these all-stars at #ACNP2026
December 2, 2025 at 4:03 PM
Honored to receive the ACNP Travel Award and looking forward to attending my first ACNP conference in the Bahamas! #ACNP2026 @acnporg.bsky.social
Reposted by Iris Ka-Yi Chat
Dr. Iris Ka-Yi Chat explores neurobiological mechanisms of motivation deficits & anhedonia, with a focus on immune function, reward processes, and their crosstalk in adolescents and emerging adults π§ #ACNP2026 / @iriskayichat.bsky.social
December 1, 2025 at 6:01 PM
Dr. Iris Ka-Yi Chat explores neurobiological mechanisms of motivation deficits & anhedonia, with a focus on immune function, reward processes, and their crosstalk in adolescents and emerging adults π§ #ACNP2026 / @iriskayichat.bsky.social
November 21, 2025 at 2:57 AM
Reposted by Iris Ka-Yi Chat
Are you working on #CancerNeuroscience and presenting at #SfN? Let me know! I want to come see your talk or poster and the app is really not helpful for locating your info π€. Drop it in 𧡠please π
November 15, 2025 at 6:59 PM
Are you working on #CancerNeuroscience and presenting at #SfN? Let me know! I want to come see your talk or poster and the app is really not helpful for locating your info π€. Drop it in 𧡠please π
Reposted by Iris Ka-Yi Chat
If you use the Monetary Incentive Delay task or any task with complex events in fMRI, you should read this. We demonstrate that common modeling approaches can result in bias due to omitted variables. By @jeanette-mumford.bsky.social & the ABCD task fMRI team. direct.mit.edu/imag/article...
Unintended bias in the pursuit of collinearity solutions in fMRI analysis
Abstract. In task functional magnetic resonance imaging (fMRI), collinearity between task regressors in time series models may impact power. When collinearity is identified after data collection, rese...
direct.mit.edu
October 29, 2025 at 1:23 PM
If you use the Monetary Incentive Delay task or any task with complex events in fMRI, you should read this. We demonstrate that common modeling approaches can result in bias due to omitted variables. By @jeanette-mumford.bsky.social & the ABCD task fMRI team. direct.mit.edu/imag/article...
Developing interferon-Ξ² as a safe in vivo experimental-medicine model of human inflammation
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Developing interferon-Ξ² as a safe in vivo experimental-medicine model of human inflammation
Inflammation is increasingly implicated in a wide range of neuropsychiatric and neurodegenerative disorders from depression to dementia. Compelling evβ¦
www.sciencedirect.com
November 7, 2025 at 1:26 AM
Developing interferon-Ξ² as a safe in vivo experimental-medicine model of human inflammation
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Iris Ka-Yi Chat
If you're a member of the HiTOP Society, I hope you'll consider voting for me for President π
I'd be delighted to lead us in this new chapter
Ballots went out today so we can join the current deluge of exciting election results
And whether or not you vote for me - please do vote!
I'd be delighted to lead us in this new chapter
Ballots went out today so we can join the current deluge of exciting election results
And whether or not you vote for me - please do vote!
November 5, 2025 at 10:06 PM
If you're a member of the HiTOP Society, I hope you'll consider voting for me for President π
I'd be delighted to lead us in this new chapter
Ballots went out today so we can join the current deluge of exciting election results
And whether or not you vote for me - please do vote!
I'd be delighted to lead us in this new chapter
Ballots went out today so we can join the current deluge of exciting election results
And whether or not you vote for me - please do vote!
Reposted by Iris Ka-Yi Chat
Iβve spent the last 8 years(!) working from the position that HiTOP relies too much on analyses of traditional diagnoses, baking in limitations of the DSM, and that we need to move to symptom-level analyses to fix it
It turns out that rebuilding HiTOP from the ground up doesnβt change much π
1/
It turns out that rebuilding HiTOP from the ground up doesnβt change much π
1/
November 4, 2025 at 8:27 PM
Iβve spent the last 8 years(!) working from the position that HiTOP relies too much on analyses of traditional diagnoses, baking in limitations of the DSM, and that we need to move to symptom-level analyses to fix it
It turns out that rebuilding HiTOP from the ground up doesnβt change much π
1/
It turns out that rebuilding HiTOP from the ground up doesnβt change much π
1/
Reposted by Iris Ka-Yi Chat
Excited to share that Iβll be reviewing applications for the Clinical Child Psychology Program at the University of Houston this cycle!
If youβre interested in clinical neuroscience research of autism, please consider applying to join our growing team.
More info here: www.uh.edu/class/psycho...
If youβre interested in clinical neuroscience research of autism, please consider applying to join our growing team.
More info here: www.uh.edu/class/psycho...
Clinical Psychology Program in the Department of Psychology at UH | Department of Psychology | University of Houston
College of Liberal Arts and Social Sciences
www.uh.edu
October 21, 2025 at 5:33 PM
Excited to share that Iβll be reviewing applications for the Clinical Child Psychology Program at the University of Houston this cycle!
If youβre interested in clinical neuroscience research of autism, please consider applying to join our growing team.
More info here: www.uh.edu/class/psycho...
If youβre interested in clinical neuroscience research of autism, please consider applying to join our growing team.
More info here: www.uh.edu/class/psycho...
Reposted by Iris Ka-Yi Chat
Obesity, low-grade inflammation, and inflammatory response to immune challenge modulate willingness to expend effort for reward: https://osf.io/xtkw7
October 30, 2025 at 3:42 PM
Obesity, low-grade inflammation, and inflammatory response to immune challenge modulate willingness to expend effort for reward: https://osf.io/xtkw7
Reposted by Iris Ka-Yi Chat
The role of subcortical brain tissue iron as an indicator of dopamine neurophysiology in adolescent cannabis use: https://osf.io/rfh6k
October 30, 2025 at 3:42 PM
The role of subcortical brain tissue iron as an indicator of dopamine neurophysiology in adolescent cannabis use: https://osf.io/rfh6k
Reposted by Iris Ka-Yi Chat
Submit your symposia proposals for the #PNIRS2026 Annual Meeting in New Orleans! This year's meeting theme is Modifiable Risk Factors Across the Lifespan.
More info and submission site here: mss-abstracts.pnirs.org
More info and submission site here: mss-abstracts.pnirs.org
October 11, 2025 at 4:35 PM
Submit your symposia proposals for the #PNIRS2026 Annual Meeting in New Orleans! This year's meeting theme is Modifiable Risk Factors Across the Lifespan.
More info and submission site here: mss-abstracts.pnirs.org
More info and submission site here: mss-abstracts.pnirs.org