Hugo van den Hoek
@hugovdhoek.bsky.social
Cryo-ET of eukaryotic cells & cilia 🔬👨🔬
Looking at tiny slices of frozen cells in 3D🦠
Former Engel Lab, Biozentrum, Uni Basel 🇨🇭🏡
Metalhead, he/him. Nature is hella strange and I'm all here for it 🤓🕵🏼♂️
Looking at tiny slices of frozen cells in 3D🦠
Former Engel Lab, Biozentrum, Uni Basel 🇨🇭🏡
Metalhead, he/him. Nature is hella strange and I'm all here for it 🤓🕵🏼♂️
Reposted by Hugo van den Hoek
Woo! Very excited to share our collaborative work on the centriole's Luminal Distal Ring ⭕. This project started 13 years ago with @hugovdhoek.bsky.social & @stearnslab.bsky.social, and then beautifully came together with @computingcaitie.bsky.social & @centriolelab.bsky.social.
#TeamTomo #UExM 🧪🧶🧬🔬
#TeamTomo #UExM 🧪🧶🧬🔬
🚨 New preprint!
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...
June 19, 2025 at 9:41 AM
Woo! Very excited to share our collaborative work on the centriole's Luminal Distal Ring ⭕. This project started 13 years ago with @hugovdhoek.bsky.social & @stearnslab.bsky.social, and then beautifully came together with @computingcaitie.bsky.social & @centriolelab.bsky.social.
#TeamTomo #UExM 🧪🧶🧬🔬
#TeamTomo #UExM 🧪🧶🧬🔬
Reposted by Hugo van den Hoek
We’re kicking off the DinoSphere Online Seminar Series! Join us for our first session with Karel Mockaer (Heidelberg) & Yong Heng Phua (OIST)
📅 1 July 9AM CEST
🔗 tinyurl.com/4mjaverj
Spread the word!
@protistwtmostest.bsky.social @ehehenberger.bsky.social @chandnibhickta.bsky.social&Norico Yamada
📅 1 July 9AM CEST
🔗 tinyurl.com/4mjaverj
Spread the word!
@protistwtmostest.bsky.social @ehehenberger.bsky.social @chandnibhickta.bsky.social&Norico Yamada
June 4, 2025 at 4:34 AM
We’re kicking off the DinoSphere Online Seminar Series! Join us for our first session with Karel Mockaer (Heidelberg) & Yong Heng Phua (OIST)
📅 1 July 9AM CEST
🔗 tinyurl.com/4mjaverj
Spread the word!
@protistwtmostest.bsky.social @ehehenberger.bsky.social @chandnibhickta.bsky.social&Norico Yamada
📅 1 July 9AM CEST
🔗 tinyurl.com/4mjaverj
Spread the word!
@protistwtmostest.bsky.social @ehehenberger.bsky.social @chandnibhickta.bsky.social&Norico Yamada
Reposted by Hugo van den Hoek
Reposted by Hugo van den Hoek
To all #TeamTomo #CryoET and #Chlamydomonas aficionados: we have updated EMPIAR-11830 with a bug fix concerning some cryo-CARE denoised tomos as well as additional files and metadata! 🎉👩🏽💻
www.ebi.ac.uk/empiar/EMPIA...
A little thread about what's new... 🧵 1/n
www.ebi.ac.uk/empiar/EMPIA...
A little thread about what's new... 🧵 1/n
February 28, 2025 at 4:35 PM
To all #TeamTomo #CryoET and #Chlamydomonas aficionados: we have updated EMPIAR-11830 with a bug fix concerning some cryo-CARE denoised tomos as well as additional files and metadata! 🎉👩🏽💻
www.ebi.ac.uk/empiar/EMPIA...
A little thread about what's new... 🧵 1/n
www.ebi.ac.uk/empiar/EMPIA...
A little thread about what's new... 🧵 1/n
February 4, 2025 at 12:07 PM
Sigh. A big warm hug to y'all. Undoing a #dictatorship will not be easy.
#Science, #Census, #USAID and many more #institutions have already fallen. Their datasets etc has been erased. No access. It's going so fast.
I wish you all the strength in the world and more💕 I'm afraid you're gonna need it
#Science, #Census, #USAID and many more #institutions have already fallen. Their datasets etc has been erased. No access. It's going so fast.
I wish you all the strength in the world and more💕 I'm afraid you're gonna need it
February 4, 2025 at 10:03 AM
Sigh. A big warm hug to y'all. Undoing a #dictatorship will not be easy.
#Science, #Census, #USAID and many more #institutions have already fallen. Their datasets etc has been erased. No access. It's going so fast.
I wish you all the strength in the world and more💕 I'm afraid you're gonna need it
#Science, #Census, #USAID and many more #institutions have already fallen. Their datasets etc has been erased. No access. It's going so fast.
I wish you all the strength in the world and more💕 I'm afraid you're gonna need it
Reposted by Hugo van den Hoek
Hey #TeamTomo❄️🔬 computer wizards!👩💻🧙♂️ This is an amazing opportunity for a permanent position working alongside the fantastic Alicia Michael and Florian Schur, pushing #CryoET image analysis of chromatin and actin networks inside native cells!🧬🧶🧪 Vienna's not a bad place to be either.🍻😁
Interested in computation, cryoEM/ET, image analysis? How about working in a TT position at a cutting-edge institution just outside one of the most livable cities? Come join us at the Institute of Science and Technology Austria!
More info here: ist.ac.at/en/job/staff...
Reach out for more info!
More info here: ist.ac.at/en/job/staff...
Reach out for more info!
Staff Scientist – Computational Analysis of Cryo-Electron Microscopy / Electron Tomography Data
Staff Scientists at ISTA (www.ista.ac.at) pursue research projects with professors, serving as collaborators with expertise normally not present within research groups. We are searching for a Staff Sc...
ist.ac.at
January 9, 2024 at 8:27 PM
Hey #TeamTomo❄️🔬 computer wizards!👩💻🧙♂️ This is an amazing opportunity for a permanent position working alongside the fantastic Alicia Michael and Florian Schur, pushing #CryoET image analysis of chromatin and actin networks inside native cells!🧬🧶🧪 Vienna's not a bad place to be either.🍻😁
Reposted by Hugo van den Hoek
As a structural biologist there's a stage in discovery where you and your colleagues have seen an amazing structure but there's still work to do before it's ready for dissemination. You walk around knowing that every person, every living animal, carries that fascinating structure in their body.
December 20, 2023 at 12:30 AM
As a structural biologist there's a stage in discovery where you and your colleagues have seen an amazing structure but there's still work to do before it's ready for dissemination. You walk around knowing that every person, every living animal, carries that fascinating structure in their body.
Reposted by Hugo van den Hoek
Please be sure to check you kid's candy this year. I just found another project I have no time for in a Reese's cup
October 31, 2023 at 1:48 PM
Please be sure to check you kid's candy this year. I just found another project I have no time for in a Reese's cup
Reposted by Hugo van den Hoek
Meet the PyShell!🥧🐚
Diatom pyrenoids fix up to 20% of the Earth's #CO2🌏. We discovered that their Rubisco is encased in a tight protein lattice that is essential for efficient carbon fixation and cell growth🌱
Super excited to share our new preprint📜: www.biorxiv.org/content/10.1...
🌾🧪 🧶🧬 ❄️🔬
Diatom pyrenoids fix up to 20% of the Earth's #CO2🌏. We discovered that their Rubisco is encased in a tight protein lattice that is essential for efficient carbon fixation and cell growth🌱
Super excited to share our new preprint📜: www.biorxiv.org/content/10.1...
🌾🧪 🧶🧬 ❄️🔬
October 27, 2023 at 6:25 AM
Meet the PyShell!🥧🐚
Diatom pyrenoids fix up to 20% of the Earth's #CO2🌏. We discovered that their Rubisco is encased in a tight protein lattice that is essential for efficient carbon fixation and cell growth🌱
Super excited to share our new preprint📜: www.biorxiv.org/content/10.1...
🌾🧪 🧶🧬 ❄️🔬
Diatom pyrenoids fix up to 20% of the Earth's #CO2🌏. We discovered that their Rubisco is encased in a tight protein lattice that is essential for efficient carbon fixation and cell growth🌱
Super excited to share our new preprint📜: www.biorxiv.org/content/10.1...
🌾🧪 🧶🧬 ❄️🔬
Reposted by Hugo van den Hoek
Don't worry, they will have everything fixed by 2070 (not a joke) www.zdf.de/nachrichten/...
Verkehrswende: Deutschlandtakt der Bahn auf 2070 verschoben
Pünktliche Züge, kürzere Aufenthalte: Der Deutschlandtakt sollte ab 2030 das Bahnfahren revolutionieren. Daraus wird ein Jahrhundertprojekt.
www.zdf.de
October 9, 2023 at 4:21 PM
Don't worry, they will have everything fixed by 2070 (not a joke) www.zdf.de/nachrichten/...
Reposted by Hugo van den Hoek
It is my pleasure to announce the @EMBO course on “In situ structural biology by Cryo-FIB and Cryo-ET” taking place @MPI_Biochem from 8.-14. April 2024. If you are interested in learning about cryo-ET and cryo-FIB including lift-out, apply by December 8th!
meetings.embo.org/event/24-in-...
meetings.embo.org/event/24-in-...
October 9, 2023 at 2:25 PM
It is my pleasure to announce the @EMBO course on “In situ structural biology by Cryo-FIB and Cryo-ET” taking place @MPI_Biochem from 8.-14. April 2024. If you are interested in learning about cryo-ET and cryo-FIB including lift-out, apply by December 8th!
meetings.embo.org/event/24-in-...
meetings.embo.org/event/24-in-...
Reposted by Hugo van den Hoek
Walking new people through tomogram processing:
October 5, 2023 at 8:42 PM
Walking new people through tomogram processing: