It's 25 yrs to the day since the Human Genome Project & Craig Venter declared joint victory in sequencing the human genome - an ideal time for @wellcometrust.bsky.social to annouce their new project, involving our lab, to begin work towards synthesising human genomes. wellcome.org/news/researc...
Researchers take first steps to creating synthetic human genomes | Wellcome
Scientists are developing technology to create the first synthetic human chromosome. The ability to write large genomes could transform our understanding of health.
wellcome.org
June 27, 2025 at 12:37 PM
What a beautiful story and triumph! Congratulations to José and Matthias.
Proteins of amino acid metabolism form large structures and determine diffusion in the cytoplasm!
Our 7-year-long tour-de-force is now out on Bioxriv www.biorxiv.org/content/10.1...
Thanks everyone involved! And especially to Jose Losa who pioneered this!
Our 7-year-long tour-de-force is now out on Bioxriv www.biorxiv.org/content/10.1...
Thanks everyone involved! And especially to Jose Losa who pioneered this!
June 27, 2025 at 12:32 PM
What a beautiful story and triumph! Congratulations to José and Matthias.
Fantastic institute and group full of enthusiastic and friendly geeks
I, Rahuman Sheriff @biomodels.bsky.social and Ellie McDonagh from @opentargets.org @ebi.embl.org are looking for an enthusiastic postdoc with skills in executable modelling to create Digital Twins for rare disease (CZI-funded project).
Postdoctoral Fellow – Bioinformatics & Executable Modelling for Rare Disease Digital Twins
We are looking for a motivated and talented postdoctoral-level researcher with experience in executable modelling to join a cutting-edge project developing Digital Twins for rare diseases. This is a u...
embl.wd103.myworkdayjobs.com
June 13, 2025 at 6:15 PM
Fantastic institute and group full of enthusiastic and friendly geeks
Fully recommended!
2 weeks left to apply for our new fully funded postdoc position studying plasticity regulators in metastatic CRC!
We are recruiting! We're searching for a postdoctoral research fellow to study patient-specific regulators of plasticity in primary and metastatic CRC. Please reach out if you have any questions! www.ucl.ac.uk/work-at-ucl/...
June 10, 2025 at 9:08 AM
Fully recommended!
Reposted by Haoqi Chen
How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 new studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. multimodal cell atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵
May 16, 2025 at 11:44 AM
How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 new studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. multimodal cell atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵
Reposted by Haoqi Chen
Two massive glioblastoma papers, datasets, trajectories, insights, and.. a very cool new method for GRN inference - scDORI -from @steglelab.bsky.social @oliverstegle.bsky.social @bayraktarlab.bsky.social & Moritz Mall www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...
Decoding Plasticity Regulators and Transition Trajectories in Glioblastoma with Single-cell Multiomics
Glioblastoma (GB) is one of the most lethal human cancers, marked by profound intratumoral heterogeneity and near-universal treatment resistance. Cellular plasticity, the capacity of cancer cells to t...
www.biorxiv.org
May 16, 2025 at 7:31 AM
Two massive glioblastoma papers, datasets, trajectories, insights, and.. a very cool new method for GRN inference - scDORI -from @steglelab.bsky.social @oliverstegle.bsky.social @bayraktarlab.bsky.social & Moritz Mall www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...