Hannah Rickman
@hannahrickman.bsky.social
Infectious Diseases Dr / Wellcome Trust Clinical PhD fellow at LSHTM/MLW
Tuberculosis, epi, equity, climate justice
Otherwise, probably running in the mountains
she/her
Tuberculosis, epi, equity, climate justice
Otherwise, probably running in the mountains
she/her
Reposted by Hannah Rickman
NEW STUDY! 📣
A large global study found men are more likely to be exposed to TB than women.
The reason? Likely social behaviours:
• More time in crowded indoor spaces
• Delays in seeking care
READ MORE ⤵️
🔗 www.thelancet.com/journals/lan...
@petermacp.bsky.social @hannahrickman.bsky.social
A large global study found men are more likely to be exposed to TB than women.
The reason? Likely social behaviours:
• More time in crowded indoor spaces
• Delays in seeking care
READ MORE ⤵️
🔗 www.thelancet.com/journals/lan...
@petermacp.bsky.social @hannahrickman.bsky.social
July 2, 2025 at 2:36 PM
NEW STUDY! 📣
A large global study found men are more likely to be exposed to TB than women.
The reason? Likely social behaviours:
• More time in crowded indoor spaces
• Delays in seeking care
READ MORE ⤵️
🔗 www.thelancet.com/journals/lan...
@petermacp.bsky.social @hannahrickman.bsky.social
A large global study found men are more likely to be exposed to TB than women.
The reason? Likely social behaviours:
• More time in crowded indoor spaces
• Delays in seeking care
READ MORE ⤵️
🔗 www.thelancet.com/journals/lan...
@petermacp.bsky.social @hannahrickman.bsky.social
Reposted by Hannah Rickman
🚨”Amita Gupta has spent more than a decade planning and running a US$70-million trial to study a new #tuberculosis drug, enrolling nearly 6,000 participants across 13 countries. It might all have been for nothing. Gupta’s trial has been ensnared by… [new] NIH policy… that bans ‘foreign subawards’”⤵️
NIH funding will abruptly cease for dozens, if not hundreds, of ongoing overseas trials of drugs and treatments. Its policy change puts thousands of trial participants in limbo.
https://go.nature.com/3Z8xNM1
https://go.nature.com/3Z8xNM1
NIH grant cuts will axe clinical trials abroad — and could leave thousands without care
US agency’s new policy could abruptly end studies of infectious diseases and cancer, leaving researchers scrambling for funds.
go.nature.com
May 30, 2025 at 6:23 PM
🚨”Amita Gupta has spent more than a decade planning and running a US$70-million trial to study a new #tuberculosis drug, enrolling nearly 6,000 participants across 13 countries. It might all have been for nothing. Gupta’s trial has been ensnared by… [new] NIH policy… that bans ‘foreign subawards’”⤵️
Reposted by Hannah Rickman
#Tuberculosis Journal Club
**TODAY** 4pm UK time.
@jaseddon.bsky.social & Dr Amedine Duret taking us through the drivers of adolescent TB 👫
pmc.ncbi.nlm.nih.gov/articles/PMC... by Silvia Chiang, @petedodd24.bsky.social &al
Hope to see you there!
eepurl.com/hO4D79 to join mailing list ✉️
#tbsky
**TODAY** 4pm UK time.
@jaseddon.bsky.social & Dr Amedine Duret taking us through the drivers of adolescent TB 👫
pmc.ncbi.nlm.nih.gov/articles/PMC... by Silvia Chiang, @petedodd24.bsky.social &al
Hope to see you there!
eepurl.com/hO4D79 to join mailing list ✉️
#tbsky
Factors driving adolescent tuberculosis incidence by age and sex in 30 high-tuberculosis burden countries: a mathematical modelling study
During adolescence, tuberculosis incidence rises, with a greater increase in males compared with females. Tuberculosis notifications and estimates infrequently disaggregate adolescent age groups. More...
pmc.ncbi.nlm.nih.gov
March 27, 2025 at 2:20 PM
#Tuberculosis Journal Club
**TODAY** 4pm UK time.
@jaseddon.bsky.social & Dr Amedine Duret taking us through the drivers of adolescent TB 👫
pmc.ncbi.nlm.nih.gov/articles/PMC... by Silvia Chiang, @petedodd24.bsky.social &al
Hope to see you there!
eepurl.com/hO4D79 to join mailing list ✉️
#tbsky
**TODAY** 4pm UK time.
@jaseddon.bsky.social & Dr Amedine Duret taking us through the drivers of adolescent TB 👫
pmc.ncbi.nlm.nih.gov/articles/PMC... by Silvia Chiang, @petedodd24.bsky.social &al
Hope to see you there!
eepurl.com/hO4D79 to join mailing list ✉️
#tbsky
Dr Teresa Kasaeva asking a room of #TB researchers at the Steve Lawn Memorial Lecture @lshtm.bsky.social : “what are the greatest barriers to ending TB by 2030?”
“Funding”, “political commitment”, “Trump”… but I think whoever said “no one gives a s*** about poor people” nailed it.
#tbsky
“Funding”, “political commitment”, “Trump”… but I think whoever said “no one gives a s*** about poor people” nailed it.
#tbsky
March 20, 2025 at 6:14 PM
Dr Teresa Kasaeva asking a room of #TB researchers at the Steve Lawn Memorial Lecture @lshtm.bsky.social : “what are the greatest barriers to ending TB by 2030?”
“Funding”, “political commitment”, “Trump”… but I think whoever said “no one gives a s*** about poor people” nailed it.
#tbsky
“Funding”, “political commitment”, “Trump”… but I think whoever said “no one gives a s*** about poor people” nailed it.
#tbsky
Reposted by Hannah Rickman
Each day of funding cuts means 11,000 people with TB may not complete their treatment. Stopping TB programs isn't just bad policy – it’s a public health catastrophe. Countless lives are at stake! #FundTBNow #FundingCutsCostLives
February 27, 2025 at 9:37 PM
Each day of funding cuts means 11,000 people with TB may not complete their treatment. Stopping TB programs isn't just bad policy – it’s a public health catastrophe. Countless lives are at stake! #FundTBNow #FundingCutsCostLives
Brilliant presentation by Verena Faehling & chairing by Liz Corbett - thanks so much all who joined for a great discussion 👏 eepurl.com/hO4D79 to join mailing list for future sessions.
February 20, 2025 at 5:48 PM
Brilliant presentation by Verena Faehling & chairing by Liz Corbett - thanks so much all who joined for a great discussion 👏 eepurl.com/hO4D79 to join mailing list for future sessions.
Reposted by Hannah Rickman
First TB Journal Club of 2025 meets *this Thursday* 20th at 4pm UK time 🕓
Liz Corbett & Verena Faehling @lshtm.bsky.social will be discussing shorturl.at/AGD8l Duong &al 2024 meta-analysis of VQUIN & TB-CHAMP RCTs of levofloxacin for #MDRTB contacts.
Hope to see you there!
#tbsky #tuberculosis
Liz Corbett & Verena Faehling @lshtm.bsky.social will be discussing shorturl.at/AGD8l Duong &al 2024 meta-analysis of VQUIN & TB-CHAMP RCTs of levofloxacin for #MDRTB contacts.
Hope to see you there!
#tbsky #tuberculosis
A Meta-Analysis of Levofloxacin for Contacts of Multidrug-Resistant Tuberculosis
Data from randomized trials evaluating the effectiveness of tuberculosis (TB) preventive
treatment for contacts of multidrug-resistant (MDR)-TB are lacking. Two recently published
randomized trials...
shorturl.at
February 18, 2025 at 5:41 PM
First TB Journal Club of 2025 meets *this Thursday* 20th at 4pm UK time 🕓
Liz Corbett & Verena Faehling @lshtm.bsky.social will be discussing shorturl.at/AGD8l Duong &al 2024 meta-analysis of VQUIN & TB-CHAMP RCTs of levofloxacin for #MDRTB contacts.
Hope to see you there!
#tbsky #tuberculosis
Liz Corbett & Verena Faehling @lshtm.bsky.social will be discussing shorturl.at/AGD8l Duong &al 2024 meta-analysis of VQUIN & TB-CHAMP RCTs of levofloxacin for #MDRTB contacts.
Hope to see you there!
#tbsky #tuberculosis
Reposted by Hannah Rickman
Early data from @publichealthscot.bsky.social show that RSV vaccination (Pfizer ABRYSVO) in older adults aged 75-79 years was associated with 62% ⬇️ (95%CI 35-80%) in #RSV hospitalisation. 🦠🏥💉🏴👏
Vaccination commenced mid August 2024 & uptake was 68.6% by end of Nov 2024.
Vaccination commenced mid August 2024 & uptake was 68.6% by end of Nov 2024.
February 14, 2025 at 1:16 PM
Early data from @publichealthscot.bsky.social show that RSV vaccination (Pfizer ABRYSVO) in older adults aged 75-79 years was associated with 62% ⬇️ (95%CI 35-80%) in #RSV hospitalisation. 🦠🏥💉🏴👏
Vaccination commenced mid August 2024 & uptake was 68.6% by end of Nov 2024.
Vaccination commenced mid August 2024 & uptake was 68.6% by end of Nov 2024.
Reposted by Hannah Rickman
Today is International Day of Women & Girls in Science.
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
February 11, 2025 at 7:52 AM
Today is International Day of Women & Girls in Science.
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
Reposted by Hannah Rickman
A paper in Nature Medicine reports that participation in Brazil’s Bolsa Familia Program, one of the largest conditional cash transfer programs in the world, was associated with large reductions in tuberculosis incidence and mortality among various groups#Medskyky 🧪
Effects of conditional cash transfers on tuberculosis incidence and mortality according to race, ethnicity and socioeconomic factors in the 100 Million Brazilian Cohort - Nature Medicine
Participation in Brazil’s Bolsa Familia Program, one of the largest conditional cash transfer programs in the world, was associated with large reductions in tuberculosis incidence and mortality among Indigenous people, individuals of Black and Pardo ethnicity and those living in extreme poverty.
go.nature.com
January 20, 2025 at 2:31 PM
A paper in Nature Medicine reports that participation in Brazil’s Bolsa Familia Program, one of the largest conditional cash transfer programs in the world, was associated with large reductions in tuberculosis incidence and mortality among various groups#Medskyky 🧪
Reposted by Hannah Rickman
Compelling analysis suggesting that M:F difference in TB rates driven by differences in rates of Mtb infection. Consistent with old (2000) analysis of genotypic clustering (PMID: 10654640). But why do zoonotic TB series often have flipped ratios? doi: 10.1093/infdis/jiae124
New preprint (with all pre-print caveats!) tinyurl.com/589ffhu4 on Mtb infection risk by sex & age.
Men are at higher risk of #tuberculosis v women- but unclear how much driven by higher infection vs progression to disease. We meta-analysed Mtb immunoreactivity surveys to find out more🧵 #tbsky
Men are at higher risk of #tuberculosis v women- but unclear how much driven by higher infection vs progression to disease. We meta-analysed Mtb immunoreactivity surveys to find out more🧵 #tbsky
Sex Differences in the Risk of Mycobacterium Tuberculosis Infection: A Systematic Review and Meta-Analysis of Population-Based Immunoreactivity Surveys
Background: Tuberculosis (TB) killed 1·25 million people globally in 2023. Men have a 1·7-fold higher TB incidence than women, but it is not known to what exten
papers.ssrn.com
January 10, 2025 at 12:27 PM
Compelling analysis suggesting that M:F difference in TB rates driven by differences in rates of Mtb infection. Consistent with old (2000) analysis of genotypic clustering (PMID: 10654640). But why do zoonotic TB series often have flipped ratios? doi: 10.1093/infdis/jiae124
Reposted by Hannah Rickman
New pre-print led by @hannahrickman.bsky.social tinyurl.com/589ffhu4
We meta-analysed ~half a million participants from #TB infection surveys.
From adolescence, men have much higher risk of acquiring new TB infection than women. Probably due to social exposure and assortative mixing.
#IDsky 🧪🦠🛟
We meta-analysed ~half a million participants from #TB infection surveys.
From adolescence, men have much higher risk of acquiring new TB infection than women. Probably due to social exposure and assortative mixing.
#IDsky 🧪🦠🛟
January 10, 2025 at 8:45 AM
New pre-print led by @hannahrickman.bsky.social tinyurl.com/589ffhu4
We meta-analysed ~half a million participants from #TB infection surveys.
From adolescence, men have much higher risk of acquiring new TB infection than women. Probably due to social exposure and assortative mixing.
#IDsky 🧪🦠🛟
We meta-analysed ~half a million participants from #TB infection surveys.
From adolescence, men have much higher risk of acquiring new TB infection than women. Probably due to social exposure and assortative mixing.
#IDsky 🧪🦠🛟
New preprint (with all pre-print caveats!) tinyurl.com/589ffhu4 on Mtb infection risk by sex & age.
Men are at higher risk of #tuberculosis v women- but unclear how much driven by higher infection vs progression to disease. We meta-analysed Mtb immunoreactivity surveys to find out more🧵 #tbsky
Men are at higher risk of #tuberculosis v women- but unclear how much driven by higher infection vs progression to disease. We meta-analysed Mtb immunoreactivity surveys to find out more🧵 #tbsky
Sex Differences in the Risk of Mycobacterium Tuberculosis Infection: A Systematic Review and Meta-Analysis of Population-Based Immunoreactivity Surveys
Background: Tuberculosis (TB) killed 1·25 million people globally in 2023. Men have a 1·7-fold higher TB incidence than women, but it is not known to what exten
papers.ssrn.com
January 10, 2025 at 8:20 AM
New preprint (with all pre-print caveats!) tinyurl.com/589ffhu4 on Mtb infection risk by sex & age.
Men are at higher risk of #tuberculosis v women- but unclear how much driven by higher infection vs progression to disease. We meta-analysed Mtb immunoreactivity surveys to find out more🧵 #tbsky
Men are at higher risk of #tuberculosis v women- but unclear how much driven by higher infection vs progression to disease. We meta-analysed Mtb immunoreactivity surveys to find out more🧵 #tbsky
We had high hopes for an #IGRA platform overcoming barriers to use in high #tuberculosis burden settings. Unfortunately it didn't perform as expected, esp in young children #idsky #tbsky
shorturl.at/dAcPD
Great to work with a fantastic team at Malawi Liverpool Wellcome prog & @lshtm.bsky.social
shorturl.at/dAcPD
Great to work with a fantastic team at Malawi Liverpool Wellcome prog & @lshtm.bsky.social
Low concordance between QIAreach QuantiFERON-TB, a novel interferon-gamma release assay, and QuantiFERON-TB Gold Plus, in a population-based survey in Blantyre, Malawi
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shorturl.at
January 3, 2025 at 9:43 AM
We had high hopes for an #IGRA platform overcoming barriers to use in high #tuberculosis burden settings. Unfortunately it didn't perform as expected, esp in young children #idsky #tbsky
shorturl.at/dAcPD
Great to work with a fantastic team at Malawi Liverpool Wellcome prog & @lshtm.bsky.social
shorturl.at/dAcPD
Great to work with a fantastic team at Malawi Liverpool Wellcome prog & @lshtm.bsky.social
Reposted by Hannah Rickman
We urgently need a better, easier-to-use test for #TB infection.
We evaluated the QIAreach test among 1049 children and adults in 🇲🇼
Unfortunately, performance was poor & can’t be recommended for use
#TBsky #IDSky
@hannahrickman.bsky.social
doi.org/10.1128/jcm....
We evaluated the QIAreach test among 1049 children and adults in 🇲🇼
Unfortunately, performance was poor & can’t be recommended for use
#TBsky #IDSky
@hannahrickman.bsky.social
doi.org/10.1128/jcm....
December 22, 2024 at 10:05 AM
We urgently need a better, easier-to-use test for #TB infection.
We evaluated the QIAreach test among 1049 children and adults in 🇲🇼
Unfortunately, performance was poor & can’t be recommended for use
#TBsky #IDSky
@hannahrickman.bsky.social
doi.org/10.1128/jcm....
We evaluated the QIAreach test among 1049 children and adults in 🇲🇼
Unfortunately, performance was poor & can’t be recommended for use
#TBsky #IDSky
@hannahrickman.bsky.social
doi.org/10.1128/jcm....
Reposted by Hannah Rickman
REMINDER - final TBJC of 2024 is tomorrow at 4pm UK time. Look forward to seeing you there!
#tuberculosis #journalclub
#tuberculosis #journalclub
❗Final #TBJC of 2024
🕓Thurs November 28, 4pm UK
🏛️Hosts: SGUL. Chair: Sean Wasserman. Presenter: Sharenja Ratnakumar.
💊 shorturl.at/jcijg long-term efficacy & safety from STREAM2 trial of shorter regimens for #DRTB
✉️ eepurl.com/hO4D79 to join mailing list for monthly #tuberculosis journal clubs!
🕓Thurs November 28, 4pm UK
🏛️Hosts: SGUL. Chair: Sean Wasserman. Presenter: Sharenja Ratnakumar.
💊 shorturl.at/jcijg long-term efficacy & safety from STREAM2 trial of shorter regimens for #DRTB
✉️ eepurl.com/hO4D79 to join mailing list for monthly #tuberculosis journal clubs!
Long-term efficacy and safety of two short standardised regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): extended follow-up of an open-label, multicentre, randomised, ...
Both of the bedaquiline-containing regimens maintained superiority to the control
regimen, without evidence of increased mortality, providing two additional evidence-based
treatment options for patien...
shorturl.at
November 27, 2024 at 1:03 PM
REMINDER - final TBJC of 2024 is tomorrow at 4pm UK time. Look forward to seeing you there!
#tuberculosis #journalclub
#tuberculosis #journalclub
Huge huge congratulations to this amazing scientist & excellent human @rachaelburke.bsky.social 👏
🎉🎉Huge congrats to Dr Rachael Burke @rachaelburke.bsky.social on winning the Stephen Lawn Memorial Prize for #tuberculosis research🎉🎉🎉
Rachael leads amazing work improving diagnosis of TB in people with #HIV & in understanding the impact of community TB screening
*Very proud PhD supervisor!
#TBsky
Rachael leads amazing work improving diagnosis of TB in people with #HIV & in understanding the impact of community TB screening
*Very proud PhD supervisor!
#TBsky
November 21, 2024 at 2:44 PM
Huge huge congratulations to this amazing scientist & excellent human @rachaelburke.bsky.social 👏
Reposted by Hannah Rickman
Read this amazing preprint today: ~2% (156M) of the world recently infected with #tb.
Between 4.9%~7.7% have viable infection.
But emphasises we need +++ data on Mtb infection
@aschwalbc.bsky.social @kchorton.bsky.social @petedodd24.bsky.social @reinhouben.bsky.social @hannahrickman.bsky.social
Between 4.9%~7.7% have viable infection.
But emphasises we need +++ data on Mtb infection
@aschwalbc.bsky.social @kchorton.bsky.social @petedodd24.bsky.social @reinhouben.bsky.social @hannahrickman.bsky.social
November 18, 2024 at 3:59 PM
Read this amazing preprint today: ~2% (156M) of the world recently infected with #tb.
Between 4.9%~7.7% have viable infection.
But emphasises we need +++ data on Mtb infection
@aschwalbc.bsky.social @kchorton.bsky.social @petedodd24.bsky.social @reinhouben.bsky.social @hannahrickman.bsky.social
Between 4.9%~7.7% have viable infection.
But emphasises we need +++ data on Mtb infection
@aschwalbc.bsky.social @kchorton.bsky.social @petedodd24.bsky.social @reinhouben.bsky.social @hannahrickman.bsky.social
Final TB Journal Club of 2024! Hope to see you there.
❗Final #TBJC of 2024
🕓Thurs November 28, 4pm UK
🏛️Hosts: SGUL. Chair: Sean Wasserman. Presenter: Sharenja Ratnakumar.
💊 shorturl.at/jcijg long-term efficacy & safety from STREAM2 trial of shorter regimens for #DRTB
✉️ eepurl.com/hO4D79 to join mailing list for monthly #tuberculosis journal clubs!
🕓Thurs November 28, 4pm UK
🏛️Hosts: SGUL. Chair: Sean Wasserman. Presenter: Sharenja Ratnakumar.
💊 shorturl.at/jcijg long-term efficacy & safety from STREAM2 trial of shorter regimens for #DRTB
✉️ eepurl.com/hO4D79 to join mailing list for monthly #tuberculosis journal clubs!
Long-term efficacy and safety of two short standardised regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): extended follow-up of an open-label, multicentre, randomised, ...
Both of the bedaquiline-containing regimens maintained superiority to the control
regimen, without evidence of increased mortality, providing two additional evidence-based
treatment options for patien...
shorturl.at
November 18, 2024 at 12:07 PM
Final TB Journal Club of 2024! Hope to see you there.
Reposted by Hannah Rickman
We host monthly online international journal clubs on the latest #tuberculosis literature. We welcome researchers, clinicians, and anyone else interested in #TB - eepurl.com/hO4D79 to join the mailing list & hear about future meetings.
TB Journal Club
TB Journal Club Email Forms
eepurl.com
November 18, 2024 at 10:27 AM
We host monthly online international journal clubs on the latest #tuberculosis literature. We welcome researchers, clinicians, and anyone else interested in #TB - eepurl.com/hO4D79 to join the mailing list & hear about future meetings.
Reposted by Hannah Rickman
1/📢 In our new PREPRINT - tinyurl.com/yc6kbay9 - we estimate that 156 million people globally carry a recent, viable M. tuberculosis (Mtb) infection and are at high risk of progressing to TB disease.
Estimating the Global Burden of Viable Mycobacterium Tuberculosis Infection
Background: Estimating the proportion of individuals currently infected with Mycobacterium tuberculosis (Mtb) is key for informing global health policies. Altho
tinyurl.com
November 14, 2024 at 6:22 AM
1/📢 In our new PREPRINT - tinyurl.com/yc6kbay9 - we estimate that 156 million people globally carry a recent, viable M. tuberculosis (Mtb) infection and are at high risk of progressing to TB disease.
Reposted by Hannah Rickman
November 6, 2024 at 6:02 AM
Reposted by Hannah Rickman
DYK in 1957, Glasgow, Scotland ran the largest ever screening campaign against #tuberculosis?
715,000 people (76% of entire adult population) were X-rayed over just 5 weeks!
In a new study, we looked at the long-term impact of this campaign. journals.plos.org/plosmedicine...
#episky #idsky 🧪🛟
715,000 people (76% of entire adult population) were X-rayed over just 5 weeks!
In a new study, we looked at the long-term impact of this campaign. journals.plos.org/plosmedicine...
#episky #idsky 🧪🛟
November 5, 2024 at 8:29 PM
DYK in 1957, Glasgow, Scotland ran the largest ever screening campaign against #tuberculosis?
715,000 people (76% of entire adult population) were X-rayed over just 5 weeks!
In a new study, we looked at the long-term impact of this campaign. journals.plos.org/plosmedicine...
#episky #idsky 🧪🛟
715,000 people (76% of entire adult population) were X-rayed over just 5 weeks!
In a new study, we looked at the long-term impact of this campaign. journals.plos.org/plosmedicine...
#episky #idsky 🧪🛟