Gustavo Baldassarre
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gusbald.bsky.social
Gustavo Baldassarre
@gusbald.bsky.social
250 followers 1K following 22 posts
Medical oncologist interested in women’s cancers research and drug resistance.
Love sailing, skiing and enjoying life with friends and family.
Posts Replies Media Videos
Reposted by Gustavo Baldassarre
sigtrans-sttt.bsky.social
A review of the functions of human #CyclinDependentKinases, highlighting their roles in #cellcycle control, disease progression, & the therapeutic potential of #CDKInhibitors in #cancer & other diseases. @gusbald.bsky.social

#STTT: doi.org/10.1038/s413...
October 11, 2025 at 4:30 PM
gusbald.bsky.social
Great presentation at #CRO_Aviano_IRCCS by @biancastellac.bsky.social on genetic and #epigenetic alterations in #breast tissue. Thank you Biancastella, it was wonderful have you in Aviano!
September 10, 2025 at 6:07 PM
Reposted by Gustavo Baldassarre
sigtrans-sttt.bsky.social
This review summarizes the functions of #CyclinDependentKinases (CDKs), discusses their potential roles and deregulation in human pathologies and underscores the role of CDK inhibitors as standard therapies in #cancer. #medsky @gusbald.bsky.social @gustavo_baldassarre

#OpenAccess: buff.ly/NA2B1Fs
August 13, 2025 at 4:30 PM
gusbald.bsky.social
Sunset from #Monte_Faito #Campania #Italy. From right to left you can admire the Vesuvius Vulcan, Monte di Procida, the islands Procida, Ischia and Capri and the peninsula Sorrentina. This is the magnificent #gulf_of_Napoli
August 10, 2025 at 1:52 AM
gusbald.bsky.social
Sunrise at #Scilla #Calabria Italy! Just beautiful!!
August 10, 2025 at 1:15 AM
gusbald.bsky.social
www.linkedin.com/posts/gustav...
The abstract submission for #BIG2025 are open now. | Gustavo Baldassarre
The abstract submission for #BIG2025 are open now. If you are interested in presenting your work on the #surgery, #medical_therapy or #translational_research in #gynecological_cancers don't miss ...
www.linkedin.com
June 14, 2025 at 12:33 PM
gusbald.bsky.social
Just out in #Molecular_Cancer a beautiful journey with Ivana de la Serna and Francois Vallette discussing #cancer_cells #clonal_evolution and #resistance to treatments from 3 different and complementary points of view. Hope you will enjoy read this review as we enjoyed writing it.

rdcu.be/emfur
Death-ision: the link between cellular resilience and cancer resistance to treatments
rdcu.be
May 16, 2025 at 1:29 PM
gusbald.bsky.social
Free registration open for BIG2025.
Limited on site places. All info on: 👇
ecm.meetingsrl.eu/BIG2025/defa...

Registration for ITALIAN PARTICIPANT 👇
ecm.meetingsrl.eu/BIG2025/defa...

Registration forFOREIGN PARTICIPANT 👇
www.meetingsrl.eu/registration...

Meet the speakers
See you in Venice
May 10, 2025 at 5:51 PM
gusbald.bsky.social
Free registration open for BIG2025.
Limited on site places. All info on: 👇
ecm.meetingsrl.eu/BIG2025/defa...

Registration for ITALIAN PARTICIPANT 👇
ecm.meetingsrl.eu/BIG2025/defa...

Registration forFOREIGN PARTICIPANT 👇
www.meetingsrl.eu/registration...

Meet the speakers
May 10, 2025 at 5:48 PM
gusbald.bsky.social
Here we are!
Registration for BIG 2025 is now open. All info on: 👇
ecm.meetingsrl.eu/BIG2025/defa...

Registration for ITALIAN PARTICIPANT 👇
ecm.meetingsrl.eu/BIG2025/defa...

Registration forFOREIGN PARTICIPANT 👇
www.meetingsrl.eu/registration...

See you in Venice
May 9, 2025 at 5:30 PM
gusbald.bsky.social
Beautiful manuscript just published in @nature.com suggesting that a shorter #cell_cycle duration is associated to a higher possibility of cell transformation. Here is the link👇🏻

rdcu.be/ek1vB
Cell cycle duration determines oncogenic transformation capacity
Nature - Total cell cycle duration is a key hallmark of cancer initiation, and determines whether defects in apoptosis, senescence, immune surveillance, angiogenesis, DNA repair, polarity and...
rdcu.be
May 7, 2025 at 1:11 PM
gusbald.bsky.social
The 4th edition of BIG is approaching. An exceptional panel of speakers discussing the novelties in #translational and #clinical #gynecology_oncology. Free registration but limited places. Below, you can see the venue and meet the organizers. Stay tuned for updates. See you in #Venice
April 26, 2025 at 10:59 AM
gusbald.bsky.social
Safeguarding the future of biomedical science in the United States: Cell www.cell.com/cell/fulltex...
Safeguarding the future of biomedical science in the United States
NIH’s abrupt decision to cap indirect cost reimbursement at 15% threatens the critical infrastructure supporting groundbreaking biomedical research in the United States. This policy jeopardizes Americ...
www.cell.com
March 19, 2025 at 9:02 AM
Reposted by Gustavo Baldassarre
scifri.bsky.social
90% of people diagnosed with pancreatic cancer die from the disease. That's why the medical community is excited about the results of a small trial in which nearly half of the pancreatic cancer patients who received an mRNA vaccine for the disease remained relapse-free three years later.
A Vaccine For Pancreatic Cancer Continues To Show Promise
In a small trial, nearly half of pancreatic cancer patients who received an mRNA vaccine for the disease had no relapse three years later.
www.sciencefriday.com
March 16, 2025 at 2:09 PM
Reposted by Gustavo Baldassarre
barbmarte.bsky.social
new out in @nature.com www.nature.com/articles/s41...
Evolutionary fingerprints of epithelial-to-mesenchymal transition - Nature
Malignant cells with mesenchymal features display increased chromatin accessibility, particularly in the pericentromeric and centromeric regions, in turn resulting in delayed mitosis and catastrophic ...
www.nature.com
March 6, 2025 at 8:26 AM
gusbald.bsky.social
The 4th edition of BIG is approaching. Don’t miss the opportunity to joining us and meet an exceptional panel of speakers in the wonderful city of Venice. Stay tuned for further updates
March 6, 2025 at 10:12 AM
Reposted by Gustavo Baldassarre
nicorobine.bsky.social
7 new Cancer Grand Challenges announced:

www.cancergrandchallenges.org/new-challenges
@cancergrand.bsky.social
New challenges
Explore the challenges currently open for Expressions of Interest.
www.cancergrandchallenges.org
March 5, 2025 at 3:16 PM
Reposted by Gustavo Baldassarre
merz.bsky.social
Right now, I can't open:
www.nlm.nih.gov
ftp.ncbi.nlm.nih.gov
www.ncbi.nlm.nih.gov
www.ncbi.nlm.nih.gov/genbank/
pubmed.ncbi.nlm.nih.gov
alexwenzel.bsky.social Alex Wenzel @alexwenzel.bsky.social · Mar 1
NIH is taking down some PubMed/PMC services.
This site can't be reached Check if there is a typo in ftp.ncbi.nlm.nih.gov DNS_PROBE_FINISHED_NXDOMAIN
March 1, 2025 at 9:50 PM
Reposted by Gustavo Baldassarre
plantepigenetics.ch
As we can expect PubMed dysfunction more and more or to be swamped with fake journals I suggest you get acquainted to this nice alternative: europepmc.org
Europe PMCHome - Europe PMC
Europe PMC is an archive of life sciences journal literature.
europepmc.org
March 2, 2025 at 7:54 AM
Reposted by Gustavo Baldassarre
surfinnurd.bsky.social
Remember, EuropePMC is actually better than #PubMed because it includes ALL preprints in search results, not just those including NIH-funded research.

europepmc.org
Europe PMCHome - Europe PMC
Europe PMC is an archive of life sciences journal literature.
europepmc.org
March 2, 2025 at 8:28 AM
gusbald.bsky.social
Enjoying skiing on Dolomiti alps in a sunny, cold Saturday with old friends! What a day!
February 15, 2025 at 6:24 PM
Reposted by Gustavo Baldassarre
gusbald.bsky.social
What a great start to 2025 having our review on the role of hashtag#CDKs in human physiology and diseases just published in #Signal_Transduction_Targeted_Therapies!
Here is the link to the open access article 👇
rdcu.be/d6a4g
A big effort of the lab but we learnt a lot!
I hope you will enjoy it
Cyclin-dependent protein kinases and cell cycle regulation in biology and disease
Signal Transduction and Targeted Therapy - Cyclin-dependent protein kinases and cell cycle regulation in biology and disease
rdcu.be
January 14, 2025 at 8:33 PM
gusbald.bsky.social
What a great start to 2025 having our review on the role of hashtag#CDKs in human physiology and diseases just published in #Signal_Transduction_Targeted_Therapies!
Here is the link to the open access article 👇
rdcu.be/d6a4g
A big effort of the lab but we learnt a lot!
I hope you will enjoy it
Cyclin-dependent protein kinases and cell cycle regulation in biology and disease
Signal Transduction and Targeted Therapy - Cyclin-dependent protein kinases and cell cycle regulation in biology and disease
rdcu.be
January 14, 2025 at 8:33 PM
Reposted by Gustavo Baldassarre
thedailypub.bsky.social
Cyclin Dependent Kinases (CDKs) are crucial for cell division and exist in 20 variations, each with unique roles. Their malfunction is linked to diseases like cancer and Alzheimer's. CDK inhibitors are now cancer treatments, and exploring their use in other diseases could help improve patient care.
Cyclin-dependent protein kinases and cell cycle regulation in biology and disease.
Published in Signal transduction and targeted therapy
doi.org
January 13, 2025 at 8:00 AM
Reposted by Gustavo Baldassarre
atranscendedman.bsky.social
Scientists in Italy show how cyclin-dependent kinases (CDKs) regulate cell division, gene expression, and DNA repair.

Disrupted CDKs fuel diseases like cancer, making them critical targets for therapy.

www.nature.com/articles/s41...
Cyclin-dependent protein kinases and cell cycle regulation in biology and disease - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - Cyclin-dependent protein kinases and cell cycle regulation in biology and disease
www.nature.com
January 13, 2025 at 1:04 PM