Guillaume Giraud
guillaumegiraud.bsky.social
Guillaume Giraud
@guillaumegiraud.bsky.social
Tenured researcher interested in the regulatory mechanisms controlling co-transcriptional processing of hepatitis B virus RNAs and their role in chronic liver disease.
Glad to share our last preprint unveiling the role of DDX5 and DDX17 in the regulation of Hepatitis B virus RNA splicing.

www.biorxiv.org/content/10.1...
DDX5 and DDX17 RNA helicases regulate hepatitis B virus RNA splicing
Chronic HBV infection remains a major health burden worldwide and is the main driver of severe liver diseases. Liver pathogenesis is associated with the increased proportion of HBV spliced variants th...
www.biorxiv.org
February 15, 2025 at 6:10 AM
Reposted by Guillaume Giraud
1/ Pleased to share our review, published today
@natrevimmunol.bsky.social, highlighting how biomolecular condensates enhance the precision and flexibility of gene regulatory networks that guide fate decisions during normal and pathological immune cell development. www.nature.com/articles/s41...
Biomolecular condensates in immune cell fate - Nature Reviews Immunology
Recent studies suggest that biomolecular condensates — membrane-less assemblies of proteins and nucleic acids — are involved in regulating gene expression to ensure proper immune cell development. Thi...
www.nature.com
January 28, 2025 at 4:40 PM
Reposted by Guillaume Giraud
The bidirectional transfer of mitochondria between cancer and immune cells is a newly discovered mechanism that thwarts anticancer defences

https://go.nature.com/3PNuEfh
Mitochondrial swap from cancer to immune cells thwarts anti-tumour defences
Bidirectional transfer of mitochondria between cancer and immune cells.
go.nature.com
January 24, 2025 at 3:53 PM
Reposted by Guillaume Giraud
IHU Everest is organising Symposium on liver organoids and 3D ex-vivo models.
This event will be held - in person only - on February 3rd 2025, at CarMeN laboratory, on the Lyon-Sud hospital site.
Registration is free but mandatory: www.ihu-hepatolyon.fr/en/organoids...
#hepatology #organoids #IHU
Hepatic Organoïds Symposium - IHL - Institut d’Hépatologie de Lyon
Monday, February 3rd 2025 IHU Everest is organizing a Symposium on liver organoids and 3D ex-vivo models.This event will be held on Monday, February 3rd 2025, at CarMeN laboratory, on the Lyon-Sud hos...
www.ihu-hepatolyon.fr
January 21, 2025 at 10:40 AM
Reposted by Guillaume Giraud
Did you know there's an open call for submissions for a @natureportfolio.bsky.social Collection on viral #hepatitis? Only 5 years to go until WHO deadline to eliminate viral hepatitis by 2030 - let's get the research rolling!

Details: www.nature.com/collections/...

#LiverSky #HepSky #Microsky 🧪
January 17, 2025 at 6:02 PM