The students of the Computational Biology M.Sc. of Paris-Saclay (AMI2B) are delighted to organize and invite you to the Junior Conference on Computational Biology (JC2B) that will be held on November 13, 2025 at I2BC CNRS, Gif-sur-Yvette.   Paris-Saclay Junior Conference on Computational Biology Round 2025: AI and predictive models in bioinformatics November 13, 2025 — 9am to 5pm I2BC, CNRS : 91190 Gif-sur-Yvette — Auditorium Bat. 21   The Junior Conference aims to bring together the community of computational biology (Master students, PhD students, PostDocs, senior researchers, and industry professionals) from different institutions.   Selected participants will present research conducted in two main fields: Structures and Evolution and Genomics and Health. The conference also fosters discussions between participants, encourages idea sharing, and promotes collaborations. Additionally, a roundtable session will be organized for those seeking internships, traineeships, or information about Master programs.   On the program, two keynote speakers on AI and predictive models in bioinformatics: Morning session: AI applications in Structure and Evolution: Laurent Jacob (Laboratory of Computational and Quantitative Biology — CNRS, Sorbonne Université) Afternoon session: Predictive Modeling in Genomics and Health: Magali Richard (Laboratory of Translational Research and Innovation in Medicine and Complexity — CNRS, Université Grenoble Alpes)   More selected abstract presentations from participants are to be announced.   Registrations to participate are now open until October 20, 2025.   Please note that registration is mandatory whether you are presenting an abstract or attending as a participant. For more information about the full program, check the JC2B webpage.

Abstract. The classification of living systems presents significant challenges due to the prevalence of gene transfer between genomes. Traditional taxonomi