Giusy Mariano
@giusym1990.bsky.social
Group Leader/MRC Fellow at the University of Glasgow
Website: marianolab.com/home
Website: marianolab.com/home
Pinned
Giusy Mariano
@giusym1990.bsky.social
· Oct 1
🚨PhD Opportunity Alert🚨 Join me, @suzieh.bsky.social and @walllabuoglasgow.bsky.social to investigate how environment shapes anti-phage defences & prophage–prophage conflict in Pseudomonas aeruginosa.
Apply here:
www.gla.ac.uk/postgraduate...
Apply here:
www.gla.ac.uk/postgraduate...
Reposted by Giusy Mariano
PhD opportunity in my lab: exploring how commensals and pathogens build biofilm communities on endotracheal (ventilator) tubes. Microbial ecology, medical microbiology and fancy imaging! Co-supervised with the fabulous Saskia Bakker and Jeremy Webb warwick.ac.uk/fac/cross_fa... #MicroSky
Dr Freya Harrison
Dr Freya Harrison
warwick.ac.uk
October 15, 2025 at 8:09 PM
PhD opportunity in my lab: exploring how commensals and pathogens build biofilm communities on endotracheal (ventilator) tubes. Microbial ecology, medical microbiology and fancy imaging! Co-supervised with the fabulous Saskia Bakker and Jeremy Webb warwick.ac.uk/fac/cross_fa... #MicroSky
🚨PhD Opportunity Alert🚨 Join me, @suzieh.bsky.social and @walllabuoglasgow.bsky.social to investigate how environment shapes anti-phage defences & prophage–prophage conflict in Pseudomonas aeruginosa.
Apply here:
www.gla.ac.uk/postgraduate...
Apply here:
www.gla.ac.uk/postgraduate...
October 1, 2025 at 7:58 PM
🚨PhD Opportunity Alert🚨 Join me, @suzieh.bsky.social and @walllabuoglasgow.bsky.social to investigate how environment shapes anti-phage defences & prophage–prophage conflict in Pseudomonas aeruginosa.
Apply here:
www.gla.ac.uk/postgraduate...
Apply here:
www.gla.ac.uk/postgraduate...
Reposted by Giusy Mariano
How the twin-arginine translocase (Tat) system manages to transport folded proteins across membranes without any leaks? To answer this fundamental question we solved the first structure of TatB3C3 complex with bound cargo. Please check out new preprint!
t.co/962Kj9pt6F
t.co/962Kj9pt6F
https://www.biorxiv.org/content/10.1101/2025.09.16.676506v1
t.co
September 18, 2025 at 5:35 PM
How the twin-arginine translocase (Tat) system manages to transport folded proteins across membranes without any leaks? To answer this fundamental question we solved the first structure of TatB3C3 complex with bound cargo. Please check out new preprint!
t.co/962Kj9pt6F
t.co/962Kj9pt6F
Reposted by Giusy Mariano
Really excited to share my first paper from the Whitney lab, alongside an amazing grad student, Polina. Here we identify a chaperone family required for the folding of a central domain of T7SS toxins, and solve the structure of the chaperone-toxin complex. www.pnas.org/doi/10.1073/...
A widespread family of molecular chaperones promotes the intracellular stability of type VIIb secretion system–exported toxins | PNAS
To survive in highly competitive environments, bacteria use specialized secretion
systems to deliver antibacterial toxins into neighboring cells, t...
www.pnas.org
September 15, 2025 at 11:41 PM
Really excited to share my first paper from the Whitney lab, alongside an amazing grad student, Polina. Here we identify a chaperone family required for the folding of a central domain of T7SS toxins, and solve the structure of the chaperone-toxin complex. www.pnas.org/doi/10.1073/...
It was a really nice experience to give a talk at Northumbria University! Very happy to get to present our work on Zorya systems for the first time - A huge thank you to @emmseveri.bsky.social and (not on bluesky?) Ciarán Kelly and Darren Smith for the invitation!
May 9, 2025 at 2:25 PM
It was a really nice experience to give a talk at Northumbria University! Very happy to get to present our work on Zorya systems for the first time - A huge thank you to @emmseveri.bsky.social and (not on bluesky?) Ciarán Kelly and Darren Smith for the invitation!
Reposted by Giusy Mariano
Really excited to share this story from Jake in the lab! We have found bacterial protein toxins that can enter Gram positive bacterial cells without the need for a receptor resulting in broad spectrum antibacterial activity.
Proteolytically activated antibacterial toxins inhibit the growth of diverse Gram-positive bacteria https://www.biorxiv.org/content/10.1101/2025.04.13.648598v1
April 14, 2025 at 7:07 AM
Really excited to share this story from Jake in the lab! We have found bacterial protein toxins that can enter Gram positive bacterial cells without the need for a receptor resulting in broad spectrum antibacterial activity.
For those of you who approached me at @microbiologysociety.org #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
April 4, 2025 at 9:46 AM
For those of you who approached me at @microbiologysociety.org #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!
Reposted by Giusy Mariano
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
January 24, 2025 at 12:07 PM
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
Reposted by Giusy Mariano
Presenting a poster at #Microbio25 today/tomorrow. Come for a chat about defence hotspots in Pseudomonas phage!
March 31, 2025 at 5:36 PM
Presenting a poster at #Microbio25 today/tomorrow. Come for a chat about defence hotspots in Pseudomonas phage!
Still time left to apply!!
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
March 17, 2025 at 7:03 PM
Still time left to apply!!
Pleased to share that my main Sir Henry Wellcome Fellowship project is now published! This study provides mechanistic insights into Zorya II function. Grateful to all who contributed! Read it here:https://tinyurl.com/ZoryaII
March 9, 2025 at 6:50 AM
Pleased to share that my main Sir Henry Wellcome Fellowship project is now published! This study provides mechanistic insights into Zorya II function. Grateful to all who contributed! Read it here:https://tinyurl.com/ZoryaII
We have extended the deadline for this! If you are passionate about phage-bacteria interactions, check this out and join us!
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
February 26, 2025 at 1:31 PM
We have extended the deadline for this! If you are passionate about phage-bacteria interactions, check this out and join us!
Reposted by Giusy Mariano
🚨 #PhD opportunity! 🚨
Come and work with @evaheinz7.bsky.social and me at the University of Strathclyde (Glasgow) on an exciting project investigating the roles that #bacteriophages play in the evolution and virulence of #enterococci. 🧫🧬
Details here: www.strath.ac.uk/studywithus/...
Come and work with @evaheinz7.bsky.social and me at the University of Strathclyde (Glasgow) on an exciting project investigating the roles that #bacteriophages play in the evolution and virulence of #enterococci. 🧫🧬
Details here: www.strath.ac.uk/studywithus/...
February 8, 2025 at 10:41 AM
🚨 #PhD opportunity! 🚨
Come and work with @evaheinz7.bsky.social and me at the University of Strathclyde (Glasgow) on an exciting project investigating the roles that #bacteriophages play in the evolution and virulence of #enterococci. 🧫🧬
Details here: www.strath.ac.uk/studywithus/...
Come and work with @evaheinz7.bsky.social and me at the University of Strathclyde (Glasgow) on an exciting project investigating the roles that #bacteriophages play in the evolution and virulence of #enterococci. 🧫🧬
Details here: www.strath.ac.uk/studywithus/...
Reposted by Giusy Mariano
📌 WE ARE HIRING!
@uofgsii.bsky.social is seeking to appoint a Research Associate in Molecular Microbiology.
⏺️ Vacancy Ref: 164773
⌛️ Closing date: 24 Feb 2025
📧 Informal Enquiries: Dr @giusym1990.bsky.social Giusy.Mariano@glasgow.ac.uk
More Info | How To Apply: www.jobs.gla.ac.uk/job/research...
@uofgsii.bsky.social is seeking to appoint a Research Associate in Molecular Microbiology.
⏺️ Vacancy Ref: 164773
⌛️ Closing date: 24 Feb 2025
📧 Informal Enquiries: Dr @giusym1990.bsky.social Giusy.Mariano@glasgow.ac.uk
More Info | How To Apply: www.jobs.gla.ac.uk/job/research...
February 21, 2025 at 1:41 PM
📌 WE ARE HIRING!
@uofgsii.bsky.social is seeking to appoint a Research Associate in Molecular Microbiology.
⏺️ Vacancy Ref: 164773
⌛️ Closing date: 24 Feb 2025
📧 Informal Enquiries: Dr @giusym1990.bsky.social Giusy.Mariano@glasgow.ac.uk
More Info | How To Apply: www.jobs.gla.ac.uk/job/research...
@uofgsii.bsky.social is seeking to appoint a Research Associate in Molecular Microbiology.
⏺️ Vacancy Ref: 164773
⌛️ Closing date: 24 Feb 2025
📧 Informal Enquiries: Dr @giusym1990.bsky.social Giusy.Mariano@glasgow.ac.uk
More Info | How To Apply: www.jobs.gla.ac.uk/job/research...
Still time to apply! Join us in Glasgow—be part of my team. Closing date: Feb 24th
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
February 18, 2025 at 5:25 AM
Still time to apply! Join us in Glasgow—be part of my team. Closing date: Feb 24th
Love phage-bacteria interactions, anti-phage systems, and a sprinkle of evolutionary biology? There’s still time to apply and join our team in Glasgow at @uofgsii.bsky.social !
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
February 10, 2025 at 6:51 PM
Love phage-bacteria interactions, anti-phage systems, and a sprinkle of evolutionary biology? There’s still time to apply and join our team in Glasgow at @uofgsii.bsky.social !
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
January 24, 2025 at 12:07 PM
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
Happy to share the final version of our paper on Serratia defence islands. Congrats to first-authors Tom and Suraj, and a big thank you to Blowerlab and @stephenrgarrett.bsky.social tinyurl.com/3vnyvufa
December 16, 2024 at 10:23 AM
Happy to share the final version of our paper on Serratia defence islands. Congrats to first-authors Tom and Suraj, and a big thank you to Blowerlab and @stephenrgarrett.bsky.social tinyurl.com/3vnyvufa
Over the moon to share some amazing news—I’ve been awarded an MRC Career Development Award to pursue my research at the University of Glasgow !! 🎉 Can’t wait to get started on this exciting new chapter. Stay tuned—I’ll soon be advertising a PDRA position!
December 11, 2024 at 5:34 PM
Over the moon to share some amazing news—I’ve been awarded an MRC Career Development Award to pursue my research at the University of Glasgow !! 🎉 Can’t wait to get started on this exciting new chapter. Stay tuned—I’ll soon be advertising a PDRA position!
"Now that shipments are booked and the flat is moved, it’s official… Starting from January, I’m thrilled to announce that my lab is moving to the University of Glasgow! 🎉 More good news will follow soon—once I’m free to share them! Very happy to return to Scotland 🧪✨
November 29, 2024 at 11:37 AM
"Now that shipments are booked and the flat is moved, it’s official… Starting from January, I’m thrilled to announce that my lab is moving to the University of Glasgow! 🎉 More good news will follow soon—once I’m free to share them! Very happy to return to Scotland 🧪✨
Reposted by Giusy Mariano
News on the Zorya defense system: anchors to the peptidoglycan and detects membrane disruption by phage. It has a flagella-motor-like device that rotates once activated. So cool! I've been waiting for insights on Zorya since we first described it 5 years ago. Congrats Tylor&co!
t.co/WFvS9FePB5
t.co/WFvS9FePB5
December 19, 2023 at 6:14 AM
News on the Zorya defense system: anchors to the peptidoglycan and detects membrane disruption by phage. It has a flagella-motor-like device that rotates once activated. So cool! I've been waiting for insights on Zorya since we first described it 5 years ago. Congrats Tylor&co!
t.co/WFvS9FePB5
t.co/WFvS9FePB5
Reposted by Giusy Mariano
Come do a PhD with me at University of Glasgow.
3-year fully funded PhD for UK students.
Friend to Foe: Colonisation as an Entry Point for S. aureus Infectionhttps://www.findaphd.com/phds/project/fully-funded-friend-to-foe-colonisation-as-an-entry-point-for-staphylococcus-aureus-infection/?p166823
3-year fully funded PhD for UK students.
Friend to Foe: Colonisation as an Entry Point for S. aureus Infectionhttps://www.findaphd.com/phds/project/fully-funded-friend-to-foe-colonisation-as-an-entry-point-for-staphylococcus-aureus-infection/?p166823
December 11, 2023 at 3:13 PM
Come do a PhD with me at University of Glasgow.
3-year fully funded PhD for UK students.
Friend to Foe: Colonisation as an Entry Point for S. aureus Infectionhttps://www.findaphd.com/phds/project/fully-funded-friend-to-foe-colonisation-as-an-entry-point-for-staphylococcus-aureus-infection/?p166823
3-year fully funded PhD for UK students.
Friend to Foe: Colonisation as an Entry Point for S. aureus Infectionhttps://www.findaphd.com/phds/project/fully-funded-friend-to-foe-colonisation-as-an-entry-point-for-staphylococcus-aureus-infection/?p166823
Check out this competitive PhD opportunity in my lab (and with Dr Tim Downing at Pirbright Institute). If you are passionate about antiphage systems discovery and Serratia marcescens, have a look at our project in the Pathogens and Host Defences DTP tinyurl.com/HostPathDTP or get in touch!
December 8, 2023 at 7:39 PM
Check out this competitive PhD opportunity in my lab (and with Dr Tim Downing at Pirbright Institute). If you are passionate about antiphage systems discovery and Serratia marcescens, have a look at our project in the Pathogens and Host Defences DTP tinyurl.com/HostPathDTP or get in touch!
Interested in gut pathogens, anti-phage systems and phages-bacteria conflict in disease and biocontrol? Check out this competitive #PhD opportunity with me and @jaimehat.bsky.social in our BBSRC FoodBioSystems Doctoral Training Partnership t.co/Rv3b1depAY
December 8, 2023 at 7:37 PM
Interested in gut pathogens, anti-phage systems and phages-bacteria conflict in disease and biocontrol? Check out this competitive #PhD opportunity with me and @jaimehat.bsky.social in our BBSRC FoodBioSystems Doctoral Training Partnership t.co/Rv3b1depAY