George Heath
@georgerheath.bsky.social
Group leader, Bio High-Speed Atomic Force Microscopist at the University of Leeds
#AFM #membranes #biophysics #Proteins #microscopy
https://heath-afm-lab.github.io/
#AFM #membranes #biophysics #Proteins #microscopy
https://heath-afm-lab.github.io/
Pinned
George Heath
@georgerheath.bsky.social
· Nov 15
AFM starter pack. Sorry if I missed anyone, relatively small numbers at the moment. Please share, nominate others/yourself (any career stage). I will also try to add incoming new users regularly.
go.bsky.app/MSz2t33
go.bsky.app/MSz2t33
Join us in Leeds next Summer for: AFM & SPM 2026
Co-organised with Lekshmi Kailas, Kristina Rusimova, Samuel Jarvis and Jess Cole from the Royal Microscopical Society.
#AFM #SPM #Microscopy
Co-organised with Lekshmi Kailas, Kristina Rusimova, Samuel Jarvis and Jess Cole from the Royal Microscopical Society.
#AFM #SPM #Microscopy
September 24, 2025 at 1:29 PM
Join us in Leeds next Summer for: AFM & SPM 2026
Co-organised with Lekshmi Kailas, Kristina Rusimova, Samuel Jarvis and Jess Cole from the Royal Microscopical Society.
#AFM #SPM #Microscopy
Co-organised with Lekshmi Kailas, Kristina Rusimova, Samuel Jarvis and Jess Cole from the Royal Microscopical Society.
#AFM #SPM #Microscopy
Reposted by George Heath
Exciting work led by @nano-chalmers.bsky.social delivered in collaboration with @georgerheath.bsky.social introducing a rationally designed DNA origami system for the multiplexed detection of miRNA in crude RNA extracts via nanopore sensing.
August 19, 2025 at 2:24 PM
Exciting work led by @nano-chalmers.bsky.social delivered in collaboration with @georgerheath.bsky.social introducing a rationally designed DNA origami system for the multiplexed detection of miRNA in crude RNA extracts via nanopore sensing.
Squeeze more out of your AFM images with NanoLocz v1.3 💪
Download the updated version here:
github.com/George-R-Hea...
Download the updated version here:
github.com/George-R-Hea...
May 29, 2025 at 3:13 PM
Squeeze more out of your AFM images with NanoLocz v1.3 💪
Download the updated version here:
github.com/George-R-Hea...
Download the updated version here:
github.com/George-R-Hea...
Reposted by George Heath
Excited to report our latest research on new “molecular glues” that specifically lock the BRCC36 isopeptidase complex (BRISC) in an autoinhibited state and reduce interferon signalling. This first-of-its-kind approach could reshape how we target large deubiquitylase (DUB) complexes.
rdcu.be/edRwF
rdcu.be/edRwF
March 17, 2025 at 8:58 PM
Excited to report our latest research on new “molecular glues” that specifically lock the BRCC36 isopeptidase complex (BRISC) in an autoinhibited state and reduce interferon signalling. This first-of-its-kind approach could reshape how we target large deubiquitylase (DUB) complexes.
rdcu.be/edRwF
rdcu.be/edRwF
Reposted by George Heath
Reposted by George Heath
The abstract submissions deadline for #mmc2025 has been extended!
Submit your abstract by *Friday 28 February* and join our impressive line-up of speakers!
rms.org.uk/resource/mmc...
@rmsearlycareer.bsky.social @bioimaginguk.bsky.social @yorkbioimaging.bsky.social @micro-au.bsky.social
Submit your abstract by *Friday 28 February* and join our impressive line-up of speakers!
rms.org.uk/resource/mmc...
@rmsearlycareer.bsky.social @bioimaginguk.bsky.social @yorkbioimaging.bsky.social @micro-au.bsky.social
February 17, 2025 at 11:22 AM
The abstract submissions deadline for #mmc2025 has been extended!
Submit your abstract by *Friday 28 February* and join our impressive line-up of speakers!
rms.org.uk/resource/mmc...
@rmsearlycareer.bsky.social @bioimaginguk.bsky.social @yorkbioimaging.bsky.social @micro-au.bsky.social
Submit your abstract by *Friday 28 February* and join our impressive line-up of speakers!
rms.org.uk/resource/mmc...
@rmsearlycareer.bsky.social @bioimaginguk.bsky.social @yorkbioimaging.bsky.social @micro-au.bsky.social
Reposted by George Heath
📢Abstract submissions deadline for #mmc2025 is *tomorrow* (14 February).
Don't miss the chance to present your work at Europe's largest #microscopy and #imaging event taking place this year!
Abstract submissions: mmc-series.org.uk/conference/a...
@rmsearlycareer.bsky.social
Don't miss the chance to present your work at Europe's largest #microscopy and #imaging event taking place this year!
Abstract submissions: mmc-series.org.uk/conference/a...
@rmsearlycareer.bsky.social
February 13, 2025 at 1:01 PM
📢Abstract submissions deadline for #mmc2025 is *tomorrow* (14 February).
Don't miss the chance to present your work at Europe's largest #microscopy and #imaging event taking place this year!
Abstract submissions: mmc-series.org.uk/conference/a...
@rmsearlycareer.bsky.social
Don't miss the chance to present your work at Europe's largest #microscopy and #imaging event taking place this year!
Abstract submissions: mmc-series.org.uk/conference/a...
@rmsearlycareer.bsky.social
Reposted by George Heath
📢 New round of PhD studentships.
Open to applicants worldwide.
📅 Deadline 14th March
www.findaphd.com/phds/project...
#microsky #archaeasky #chromosome 🧬🧬🧬
@steve-quinn-lab.bsky.social @georgerheath.bsky.social
Join us in beautiful York, UK!
Open to applicants worldwide.
📅 Deadline 14th March
www.findaphd.com/phds/project...
#microsky #archaeasky #chromosome 🧬🧬🧬
@steve-quinn-lab.bsky.social @georgerheath.bsky.social
Join us in beautiful York, UK!
Life pushed to extremes: probing the mechanisms of chromosome segregation in thermophilic Archaea at University of York on FindAPhD.com
PhD Project - Life pushed to extremes: probing the mechanisms of chromosome segregation in thermophilic Archaea at University of York, listed on FindAPhD.com
www.findaphd.com
February 6, 2025 at 4:51 PM
📢 New round of PhD studentships.
Open to applicants worldwide.
📅 Deadline 14th March
www.findaphd.com/phds/project...
#microsky #archaeasky #chromosome 🧬🧬🧬
@steve-quinn-lab.bsky.social @georgerheath.bsky.social
Join us in beautiful York, UK!
Open to applicants worldwide.
📅 Deadline 14th March
www.findaphd.com/phds/project...
#microsky #archaeasky #chromosome 🧬🧬🧬
@steve-quinn-lab.bsky.social @georgerheath.bsky.social
Join us in beautiful York, UK!
Reposted by George Heath
Check out the latest work on RCD-1 from our lab:
www.nature.com/articles/s41...
Congrats to my labmates! 👏
#AFM #RCD-1
www.nature.com/articles/s41...
Congrats to my labmates! 👏
#AFM #RCD-1
Mechanisms of RCD-1 pore formation and membrane bending - Nature Communications
The mechanism of RCD-1 regulated cell death in fungal cells is unknown. Here, the authors use AFM to uncover two mechanisms by which RCD-1 proteins form pores in lipid membranes, and discover a membra...
www.nature.com
February 7, 2025 at 3:12 AM
Check out the latest work on RCD-1 from our lab:
www.nature.com/articles/s41...
Congrats to my labmates! 👏
#AFM #RCD-1
www.nature.com/articles/s41...
Congrats to my labmates! 👏
#AFM #RCD-1
Postdoc Varun Gupta will be presenting some great AFM in the 1st session of the Linz Winter Workshop this weekend ⛷️👏
January 28, 2025 at 11:48 AM
Postdoc Varun Gupta will be presenting some great AFM in the 1st session of the Linz Winter Workshop this weekend ⛷️👏
Reposted by George Heath
👋👋 Hi everyone! The Astbury Centre is now on Bluesky. Follow along for updates about exciting Astbury Centre science. For now, we have put together a starter pack of members of the Astbury Centre community.
January 23, 2025 at 2:37 PM
👋👋 Hi everyone! The Astbury Centre is now on Bluesky. Follow along for updates about exciting Astbury Centre science. For now, we have put together a starter pack of members of the Astbury Centre community.
Reposted by George Heath
15th January is the abstract deadline for the upcoming #AFMBioMed2025 in #Barcelona! New formats, events… I wouldn’t miss it—save the date #April2025!
January 9, 2025 at 2:15 PM
15th January is the abstract deadline for the upcoming #AFMBioMed2025 in #Barcelona! New formats, events… I wouldn’t miss it—save the date #April2025!
Reposted by George Heath
Proud to be part of this paper published in @naturecomms.bsky.social. Using high-speed AFM, we have visualized the real-time translocation of substrate polypeptide by the single molecule of SecYEG-SecA!!!
Please check this amazing video taken by high-speed AFM!!!
www.nature.com/articles/s41...
Please check this amazing video taken by high-speed AFM!!!
www.nature.com/articles/s41...
January 8, 2025 at 12:43 PM
Proud to be part of this paper published in @naturecomms.bsky.social. Using high-speed AFM, we have visualized the real-time translocation of substrate polypeptide by the single molecule of SecYEG-SecA!!!
Please check this amazing video taken by high-speed AFM!!!
www.nature.com/articles/s41...
Please check this amazing video taken by high-speed AFM!!!
www.nature.com/articles/s41...
Please share, we have #PhD opportunities for anyone interested in filming the #Biophysics of life at the nanoscale.
Full details at: heath-afm-lab.github.io/positions/
Projects based around developing and applying High-Speed Atomic Force Microscopy methods to understand molecular dynamics.
Full details at: heath-afm-lab.github.io/positions/
Projects based around developing and applying High-Speed Atomic Force Microscopy methods to understand molecular dynamics.
December 10, 2024 at 11:55 AM
Please share, we have #PhD opportunities for anyone interested in filming the #Biophysics of life at the nanoscale.
Full details at: heath-afm-lab.github.io/positions/
Projects based around developing and applying High-Speed Atomic Force Microscopy methods to understand molecular dynamics.
Full details at: heath-afm-lab.github.io/positions/
Projects based around developing and applying High-Speed Atomic Force Microscopy methods to understand molecular dynamics.
Reposted by George Heath
📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea.
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
November 23, 2024 at 1:10 PM
📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea.
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
AFM starter pack. Sorry if I missed anyone, relatively small numbers at the moment. Please share, nominate others/yourself (any career stage). I will also try to add incoming new users regularly.
go.bsky.app/MSz2t33
go.bsky.app/MSz2t33
November 15, 2024 at 12:51 PM
AFM starter pack. Sorry if I missed anyone, relatively small numbers at the moment. Please share, nominate others/yourself (any career stage). I will also try to add incoming new users regularly.
go.bsky.app/MSz2t33
go.bsky.app/MSz2t33
Reposted by George Heath
First attempt in a (loosely defined) Single-Molecule Biophysics starter pack. Please share and (self-) nominate. go.bsky.app/CteFZM5
November 13, 2024 at 8:23 AM
First attempt in a (loosely defined) Single-Molecule Biophysics starter pack. Please share and (self-) nominate. go.bsky.app/CteFZM5
Reposted by George Heath
Now out in NSMB for those who missed our biorxiv back in 2023.. bacterial ESCRT-III-like #Vipp1 forms dynamic spiral filaments on membrane! Spirals are springs that drive 3D ring formation in the spiral centre! 😵💫 wonderful collaboration with Adai Colom’s lab and @rouxlab.bsky.social
rdcu.be/dZSPQ
rdcu.be/dZSPQ
November 11, 2024 at 10:09 PM
Now out in NSMB for those who missed our biorxiv back in 2023.. bacterial ESCRT-III-like #Vipp1 forms dynamic spiral filaments on membrane! Spirals are springs that drive 3D ring formation in the spiral centre! 😵💫 wonderful collaboration with Adai Colom’s lab and @rouxlab.bsky.social
rdcu.be/dZSPQ
rdcu.be/dZSPQ
Delighted to welcome @eddierollins.bsky.social to the group as a new postdoc!
Eddie brings a wealth of expertise in bioAFM and will be applying his skills to develop high-speed AFM methods to better understand protein dynamics and interactions.
Eddie brings a wealth of expertise in bioAFM and will be applying his skills to develop high-speed AFM methods to better understand protein dynamics and interactions.
November 12, 2024 at 3:46 PM
Delighted to welcome @eddierollins.bsky.social to the group as a new postdoc!
Eddie brings a wealth of expertise in bioAFM and will be applying his skills to develop high-speed AFM methods to better understand protein dynamics and interactions.
Eddie brings a wealth of expertise in bioAFM and will be applying his skills to develop high-speed AFM methods to better understand protein dynamics and interactions.
Real time view of High Speed AFM data capture at 35fps. This is a 20nm x 20nm area showing an annexin V trimer rotating within a lattice. (Data from 2022)
#AFM #microscopy
#AFM #microscopy
November 11, 2024 at 7:49 PM
Real time view of High Speed AFM data capture at 35fps. This is a 20nm x 20nm area showing an annexin V trimer rotating within a lattice. (Data from 2022)
#AFM #microscopy
#AFM #microscopy
Reposted by George Heath
NanoLocz: Image analysis platform for AFM, high-speed AFM and localization AFM https://www.biorxiv.org/content/10.1101/2023.11.23.568405v1
NanoLocz: Image analysis platform for AFM, high-speed AFM and localization AFM https://www.biorxiv.org/content/10.1101/2023.11.23.568405v1
NanoLocz is an open-source computer program designed for high-throughput automatic processing and si
www.biorxiv.org
November 23, 2023 at 5:51 PM
NanoLocz: Image analysis platform for AFM, high-speed AFM and localization AFM https://www.biorxiv.org/content/10.1101/2023.11.23.568405v1