Felix Wiegand
fxwiegand.bsky.social
Felix Wiegand
@fxwiegand.bsky.social
👨‍💻 PhD @ Bioinformatics & Computational Oncology, UDE
🧬 Rust, data & science
🎵 Music tech & sonic tinkering
🔗 github.com/fxwiegand
We’ve added a new Snakemake meta-wrapper for creating standalone variant reports:
🔗 snakemake-wrappers.readthedocs.io/en/stable/me...
It combines Datavzrd for an interactive overview table with Alignoth for read pileup plots — all linked together in one portable HTML report.
ALIGNOTH_REPORT | Snakemake wrappers
snakemake-wrappers.readthedocs.io
November 13, 2025 at 10:29 AM
Super happy to announce a major update of our portable and interactive alignment viewer #alignoth written in #rust. The new version provides improved highlighting of specific genomic sites or regions via VCF or BED inputs and also updates the coverage plot with variants! @johanneskoester.bsky.social
October 20, 2025 at 11:15 AM
Reposted by Felix Wiegand
Our tool #vembrane has a new homepage, providing a high level summary of all the things you can do with it to transform VCF/BCF files via simple Python expressions: vembrane.github.io
Filter, tag, annotate, sort, and flexibly convert to CSV/TSV, JSON, JSONL, YAML and FHIR via a unified syntax.
Vembrane
vembrane.github.io
September 18, 2025 at 6:53 PM
Reposted by Felix Wiegand
Rust 1.90.0 is out! blog.rust-lang.org/2025/09/18/R...

Major features:
* lld as the default linker on x86_64-unknown-linux-gnu
* cargo workspace publishing support built into cargo
* more const context APIs, and stabilization of new useful APIs
Announcing Rust 1.90.0 | Rust Blog
Empowering everyone to build reliable and efficient software.
blog.rust-lang.org
September 18, 2025 at 2:17 PM
Happy to share our invited article “Komplexe Tabellen verständlich machen” just published in BIOspektrum: doi.org/10.1007/s122... about our tool #datavzrd @johanneskoester.bsky.social

⚠️ Disclaimer: The article is in German.
Komplexe Tabellen verständlich machen - BIOspektrum
BIOspektrum -
doi.org
September 5, 2025 at 7:07 AM
Reposted by Felix Wiegand
🧬 & 🖥️
✨ Secure your ticket for the German Conference on #Bioinformatics (#GCB2025)!
We are excited to welcome you to Düsseldorf starting September 22, 2025.
👉Register now and be part of #GCB2025: gcb2025.de/GCB2025_regi...
September 2, 2025 at 12:32 PM
Reposted by Felix Wiegand
A new open-source tool converts tabular data into interactive HTML reports without programming, enabling accessible data visualization and navigation across diverse scientific fields. doi.org/g9t2fn
New open-source tool makes complex data understandable
Tabular data is at the heart of scientific analysis—whether in medicine, the social sciences, or even archaeology. Making it comprehensible and usable is often a tedious task, especially when the data is extensive or complex.
techxplore.com
July 23, 2025 at 1:03 PM
Our paper on Datavzrd has been published in @plosone.org! 🥳
Datavzrd is a new tool written in Rust for creating interactive, shareable HTML reports from tabular data — no server needed.
Check it out here:
🔗 journals.plos.org/plosone/arti...

@johanneskoester.bsky.social
Datavzrd: Rapid programming- and maintenance-free interactive visualization and communication of tabular data
Tabular data, often scattered across multiple tables, is the primary output of data analyses in virtually all scientific fields. Exchange and communication of tabular data is therefore a central challenge. We present Datavzrd, a tool for creating portable, visually rich, interactive reports from tabular data in any kind of scientific discipline. Datavzrd unifies the strengths of currently common generic approaches for interactive visualization like R Shiny with the portability, ease of use and sustainability of plain spreadsheets. The generated reports do not require the maintenance of a web server nor the installation of specialized software for viewing and can simply be attached to emails, shared via cloud services, or serve as manuscript supplements. They can be specified without requiring imperative programming, thereby enabling rapid development and offering accessibility for non-computational scientists, unlocking the look and feel of dedicated manually crafted web applications without the maintenance and development burden. Datavzrd reports scale from small tables to thousands or millions of rows and offer the ability to link multiple related tables, allowing to jump between corresponding rows or hierarchically explore growing levels of detail.
journals.plos.org
July 23, 2025 at 7:54 AM
Reposted by Felix Wiegand
Cleanifier: A fast and lightweight k-mer based tool to remove contamination in microbial sequence data https://www.biorxiv.org/content/10.1101/2025.06.24.661305v1
June 27, 2025 at 10:48 PM
Reposted by Felix Wiegand
#vembrane, our tool for filtering and transforming VCF files with easy to read Python expressions has just gained a new subcommand for directly generating #HL7 #FHIR observations from VCF records. Thanks to Till Hartmann for the continued maintenance!
github.com/vembrane/vem...
GitHub - vembrane/vembrane: vembrane filters VCF records using python expressions
vembrane filters VCF records using python expressions - vembrane/vembrane
github.com
June 13, 2025 at 9:44 AM
Another major new #alignoth release is now available on #bioconda ⭐ Our read alignment plots now include a coverage plot on top as well as improved visualization of overlapping read pairs! Check out our interactive demo at alignoth.github.io/preview.html

@johanneskoester.bsky.social
May 28, 2025 at 10:56 AM
@johanneskoester.bsky.social and I just released alignoth v0.15.0! 🎉 Now with a brand-new interactive mode: just run alignoth and follow the prompts—no CLI arguments needed.

github.com/alignoth/ali...
May 26, 2025 at 12:23 PM
Reposted by Felix Wiegand
Whoops, there have been 19 new #Snakemake releases since my last update. Apart from a lot of little bug fixes, we had several usability improvements for resource and temp handling and support for more checksum algorithms when validating output files. snakemake.readthedocs.io/en/stable/pr...
Changelog | Snakemake 9.4.0 documentation
snakemake.readthedocs.io
May 15, 2025 at 2:03 PM
🚀 We just released Alignoth v0.14.0!
The HTML view now comes with a control panel, read filtering, multi-selection via shift-click, and a more interactive read info table.

Check it out: github.com/alignoth/ali...

#bioinformatics #rust #genomics #vegalite
GitHub - alignoth/alignoth: Creating alignment plots from bam files
Creating alignment plots from bam files. Contribute to alignoth/alignoth development by creating an account on GitHub.
github.com
May 6, 2025 at 1:43 PM
Reposted by Felix Wiegand
Datavzrd: Rapid programming- and maintenance-free interactive visualization and communication of tabular data www.biorxiv.org/content/10.1... 🧬🖥️🧪
April 14, 2025 at 8:01 PM
Excited to share that our preprint, Datavzrd: Rapid programming- and maintenance-free interactive visualization and communication of tabular data, is now up on bioRxiv! 🎉 #datavzrd
Datavzrd: Rapid programming- and maintenance-free interactive visualization and communication of tabular data https://www.biorxiv.org/content/10.1101/2025.04.03.647146v1
April 8, 2025 at 12:04 PM
Reposted by Felix Wiegand
Datavzrd: Rapid programming- and maintenance-free interactive visualization and communication of tabular data https://www.biorxiv.org/content/10.1101/2025.04.03.647146v1
April 8, 2025 at 10:48 AM
Reposted by Felix Wiegand
The #Datavzrd docs now show 4 example reports from various disciplines (bioinf, social, astronomy, anthropology). This illustrates how it can replace spreadsheet supplementaries with visual and interactive interfaces. Thanks to @fxwiegand.bsky.social for the work! datavzrd.github.io/docs/example...
Examples | Datavzrd 2.50.0 documentation
datavzrd.github.io
February 11, 2025 at 9:54 AM
The latest #datavzrd version introduces a new pills option to visualize multiple values in a single table cell, with each ordinal value represented by a distinct color. @johanneskoester.bsky.social datavzrd.github.io
January 29, 2025 at 12:57 PM
Reposted by Felix Wiegand
My PhD student @fxwiegand.bsky.social has released #datavzrd 2.46 (datavzrd.github.io). We have added two new subcommands: "datavzrd suggest" auto-generates a config from given tables. "datavzrd publish" automatically publishes a given report to github pages:
github.com/datavzrd/dat...
Release v2.46.0 · datavzrd/datavzrd
2.46.0 (2025-01-10) Features Add new subcommand for suggesting configurations based on files (#858) (e460e04) Add publish subcommand (#856) (1c8facc)
github.com
January 13, 2025 at 10:56 AM
Reposted by Felix Wiegand
#datavzrd has a new spell for rendering tables columns containing clinical significance terms (from ClinVar) as colored badges: datavzrd.github.io/docs/spells....
Spells | Datavzrd 2.43.1 documentation
datavzrd.github.io
November 28, 2024 at 8:25 AM