Eyal Rozenfeld
@eyalrozenfeld.bsky.social
Neuroscientist | Leon Levy Scholar, Postdoctoral fellow at the Dayu Lin Lab @NYU | PhD at the @MosheParnas Lab | https://scholar.google.com/citations?user=43zia5QAAAAJ&hl=en
Pinned
1/ 🧠 Ever wondered how different types of learning coexist in our brains? Spoiler: Sometimes, they don’t! Our new study flips the script on what we thought about memory and learning in Drosophila. Dive in for a surprising twist! 🧵👇
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Eyal Rozenfeld
Excited to share our latest work - expressing the bacterial sodium channel in fly Kenyon cells surprisingly *decreases* their excitability, thanks partly to decreased endogenous sodium channels. This prevents learning and decreases odor-evoked calcium influx doi.org/10.1113/JP28...
Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells
Abstract figure legend: We tested the effects of expressing the bacterial voltage-gated sodium channel NaChBac in the Kenyon cells of the Drosophila memory centre, the mushroom body. NaChBac expressi...
doi.org
September 1, 2025 at 4:50 PM
Excited to share our latest work - expressing the bacterial sodium channel in fly Kenyon cells surprisingly *decreases* their excitability, thanks partly to decreased endogenous sodium channels. This prevents learning and decreases odor-evoked calcium influx doi.org/10.1113/JP28...
Reposted by Eyal Rozenfeld
Congrats, Eyal! A great way to start.
✨😀Congratulations to postdocs Eyal Rozenfeld and Francesco Limone on being named 2025 Leon Levy Scholars by The New York Academy of Sciences!
@sciencelemon92.bsky.social
@eyalrozenfeld.bsky.social
@moccalin.bsky.social
@liddelowsa.bsky.social
www.nyas.org/press-releas...
@sciencelemon92.bsky.social
@eyalrozenfeld.bsky.social
@moccalin.bsky.social
@liddelowsa.bsky.social
www.nyas.org/press-releas...
The New York Academy of Sciences and the Leon Levy Foundation Announce the 2025 Leon Levy Scholars in Neuroscience - NYAS
The New York Academy of Sciences and the Leon Levy Foundation have announced the 2025 class of Leon Levy Scholars in Neuroscience.
www.nyas.org
May 9, 2025 at 12:15 PM
Congrats, Eyal! A great way to start.
Reposted by Eyal Rozenfeld
✨😀Congratulations to postdocs Eyal Rozenfeld and Francesco Limone on being named 2025 Leon Levy Scholars by The New York Academy of Sciences!
@sciencelemon92.bsky.social
@eyalrozenfeld.bsky.social
@moccalin.bsky.social
@liddelowsa.bsky.social
www.nyas.org/press-releas...
@sciencelemon92.bsky.social
@eyalrozenfeld.bsky.social
@moccalin.bsky.social
@liddelowsa.bsky.social
www.nyas.org/press-releas...
The New York Academy of Sciences and the Leon Levy Foundation Announce the 2025 Leon Levy Scholars in Neuroscience - NYAS
The New York Academy of Sciences and the Leon Levy Foundation have announced the 2025 class of Leon Levy Scholars in Neuroscience.
www.nyas.org
May 8, 2025 at 8:48 PM
✨😀Congratulations to postdocs Eyal Rozenfeld and Francesco Limone on being named 2025 Leon Levy Scholars by The New York Academy of Sciences!
@sciencelemon92.bsky.social
@eyalrozenfeld.bsky.social
@moccalin.bsky.social
@liddelowsa.bsky.social
www.nyas.org/press-releas...
@sciencelemon92.bsky.social
@eyalrozenfeld.bsky.social
@moccalin.bsky.social
@liddelowsa.bsky.social
www.nyas.org/press-releas...
Reposted by Eyal Rozenfeld
1/ Check out our Juila Manoim, Tal Camchy, @eyalrozenfeld.bsky.social, Hadas Lerner, Hao-Hsin Chang, Ran Darshan, and Ya-Hui Chou new study in @currentbiology.bsky.social. www.sciencedirect.com/science/arti...
Nonlinear high-activity neuronal excitation enhances odor discrimination
Discrimination between different signals is crucial for animals’ survival. Inhibition that suppresses weak neural activity is crucial for pattern deco…
www.sciencedirect.com
March 20, 2025 at 9:05 AM
1/ Check out our Juila Manoim, Tal Camchy, @eyalrozenfeld.bsky.social, Hadas Lerner, Hao-Hsin Chang, Ran Darshan, and Ya-Hui Chou new study in @currentbiology.bsky.social. www.sciencedirect.com/science/arti...
Reposted by Eyal Rozenfeld
I started my lab more then 4 years ago, and we have endured some very challenging times ever since.…I am very excited to share the first paper from my lab, published now in @naturemethods.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Genetically encoded biosensor for fluorescence lifetime imaging of PTEN dynamics in the intact brain - Nature Methods
A first-in-class fluorescence lifetime-based FRET sensor for phosphatase and tensin homolog (PTEN) enables the dynamic monitoring of PTEN activity in cultured cells and in vivo with high spatiotempora...
www.nature.com
February 20, 2025 at 1:10 PM
I started my lab more then 4 years ago, and we have endured some very challenging times ever since.…I am very excited to share the first paper from my lab, published now in @naturemethods.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Eyal Rozenfeld
Our story about flies on carousels is out in @currentbiology.bsky.social! After formally engaging the fantastic @clarahowcroft.bsky.social and integrating helpful reviewer feedback, we present a more concise story with detailed behavioural quantification and cooler videos! doi.org/10.1016/j.cu...
a dog sits on a merry go round while a boy sits on a scooter
ALT: a dog sits on a merry go round while a boy sits on a scooter
media.tenor.com
February 10, 2025 at 4:03 PM
Our story about flies on carousels is out in @currentbiology.bsky.social! After formally engaging the fantastic @clarahowcroft.bsky.social and integrating helpful reviewer feedback, we present a more concise story with detailed behavioural quantification and cooler videos! doi.org/10.1016/j.cu...
Reposted by Eyal Rozenfeld
So happy to see this paper out! Congrats @victoriacorbit.bsky.social and @ahmarilab.bsky.social! Lots of fond memories from running these experiments. The similarity in the behavioral and striatal neural response time course produced by driving M2 inputs was really striking.
It's a little surreal that this paper is finally out. My last paper from my PhD and likely my last mouse neuro publication ever!
Ft. @ahmarilab.bsky.social @piantadosisean.bsky.social
If you're into mouse behavior, optogenetics, and calcium imaging, here's this 🐀🔦🔬
www.cell.com/cell-reports...
Ft. @ahmarilab.bsky.social @piantadosisean.bsky.social
If you're into mouse behavior, optogenetics, and calcium imaging, here's this 🐀🔦🔬
www.cell.com/cell-reports...
Dissociable roles of central striatum and anterior lateral motor area in initiating and sustaining naturalistic behavior
Corbit et al. studied patterns of activity in corticostriatal circuits during naturally
occurring complex behavior in mice. In contrast to models in which cortex leads striatum,
these findings suggest...
www.cell.com
January 31, 2025 at 6:28 PM
So happy to see this paper out! Congrats @victoriacorbit.bsky.social and @ahmarilab.bsky.social! Lots of fond memories from running these experiments. The similarity in the behavioral and striatal neural response time course produced by driving M2 inputs was really striking.
Reposted by Eyal Rozenfeld
An early surge of norepinephrine along brainstem pathways drives sensory-evoked awakening
www.biorxiv.org/content/10.1...
Happy to see this great work (and some PdCO application) out in the wild.
www.biorxiv.org/content/10.1...
Happy to see this great work (and some PdCO application) out in the wild.
January 30, 2025 at 1:52 PM
An early surge of norepinephrine along brainstem pathways drives sensory-evoked awakening
www.biorxiv.org/content/10.1...
Happy to see this great work (and some PdCO application) out in the wild.
www.biorxiv.org/content/10.1...
Happy to see this great work (and some PdCO application) out in the wild.
Reposted by Eyal Rozenfeld
Marlin Lab’s 1st Thesis Defense ✨
Hear the science @2:30pm EST
bit.ly/MarlinLab
Have the cheers @5:00 pm EST JLG✨
Columbia Biology student Beka Stecky will share her discoveries on “What the Nose, Knows” after learning an odor predicts a stressful experience.👃🏽🧬🧪
Hear the science @2:30pm EST
bit.ly/MarlinLab
Have the cheers @5:00 pm EST JLG✨
Columbia Biology student Beka Stecky will share her discoveries on “What the Nose, Knows” after learning an odor predicts a stressful experience.👃🏽🧬🧪
January 29, 2025 at 1:25 PM
Marlin Lab’s 1st Thesis Defense ✨
Hear the science @2:30pm EST
bit.ly/MarlinLab
Have the cheers @5:00 pm EST JLG✨
Columbia Biology student Beka Stecky will share her discoveries on “What the Nose, Knows” after learning an odor predicts a stressful experience.👃🏽🧬🧪
Hear the science @2:30pm EST
bit.ly/MarlinLab
Have the cheers @5:00 pm EST JLG✨
Columbia Biology student Beka Stecky will share her discoveries on “What the Nose, Knows” after learning an odor predicts a stressful experience.👃🏽🧬🧪
Reposted by Eyal Rozenfeld
My thesis defense date is official! And yes I put my cat and Tac2 neurons on my poster 🥰
January 23, 2025 at 6:15 PM
My thesis defense date is official! And yes I put my cat and Tac2 neurons on my poster 🥰
Reposted by Eyal Rozenfeld
Antipsychotics is often used to suppress hyper-aggression. Does it really suppress aggression or just cause sedation? Antipsychotics targets dopamine receptors. Our new study revealed that dopamine modulates aggression based on animals' fighting experience.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Experience-dependent dopamine modulation of male aggression - Nature
Dopaminergic neurons in the ventral tegmental area have a role in modulating aggression in adult male mice, and this effect of dopamine depends strongly on fighting experience.
www.nature.com
January 22, 2025 at 7:38 PM
Antipsychotics is often used to suppress hyper-aggression. Does it really suppress aggression or just cause sedation? Antipsychotics targets dopamine receptors. Our new study revealed that dopamine modulates aggression based on animals' fighting experience.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Eyal Rozenfeld
Fly neuro people: has anyone tried the Ting lab’s scFLARE (or variants) for labelling active neurons in Drosophila? Thanks.
January 15, 2025 at 5:09 PM
Fly neuro people: has anyone tried the Ting lab’s scFLARE (or variants) for labelling active neurons in Drosophila? Thanks.
Reposted by Eyal Rozenfeld
🚨Postdoc and Postbac positions available in my group at the NIEHS/NIH!
Interested in investigating the neural mechanisms for social behaviors across development in a supportive environment? Make sure to apply!
Job ads in🧵Feel free to DM/email w/ questions, please RT
Interested in investigating the neural mechanisms for social behaviors across development in a supportive environment? Make sure to apply!
Job ads in🧵Feel free to DM/email w/ questions, please RT
January 16, 2025 at 3:00 AM
🚨Postdoc and Postbac positions available in my group at the NIEHS/NIH!
Interested in investigating the neural mechanisms for social behaviors across development in a supportive environment? Make sure to apply!
Job ads in🧵Feel free to DM/email w/ questions, please RT
Interested in investigating the neural mechanisms for social behaviors across development in a supportive environment? Make sure to apply!
Job ads in🧵Feel free to DM/email w/ questions, please RT
Reposted by Eyal Rozenfeld
We are hiring!
We are looking for two PhD students interested in the regulation of habit formation. Habits are useful to decrease cognitive load, but carry the risk of becoming stereotyped and hard to control - it’s hard to shake a bad habit. The fruit fly Drosophila also forms habits and we […]
We are looking for two PhD students interested in the regulation of habit formation. Habits are useful to decrease cognitive load, but carry the risk of becoming stereotyped and hard to control - it’s hard to shake a bad habit. The fruit fly Drosophila also forms habits and we […]
Original post on mastodon.social
mastodon.social
January 7, 2025 at 12:43 PM
We are hiring!
We are looking for two PhD students interested in the regulation of habit formation. Habits are useful to decrease cognitive load, but carry the risk of becoming stereotyped and hard to control - it’s hard to shake a bad habit. The fruit fly Drosophila also forms habits and we […]
We are looking for two PhD students interested in the regulation of habit formation. Habits are useful to decrease cognitive load, but carry the risk of becoming stereotyped and hard to control - it’s hard to shake a bad habit. The fruit fly Drosophila also forms habits and we […]
Reposted by Eyal Rozenfeld
New year new work from the lab! We explore whether aggression experience and observation lead to similar changes in future aggression strategy. (They do!) We perform 2-color imaging across the whole social behavior network across time and track changes www.biorxiv.org/content/10.1...
Aggression experience and observation promote shared behavioral and neural changes
The ability to observe the social behavior of others and use observed information to bias future action is a fundamental building block of social cognition. A foundational question is whether social o...
www.biorxiv.org
January 2, 2025 at 5:33 PM
New year new work from the lab! We explore whether aggression experience and observation lead to similar changes in future aggression strategy. (They do!) We perform 2-color imaging across the whole social behavior network across time and track changes www.biorxiv.org/content/10.1...
Reposted by Eyal Rozenfeld
(1/6) Excited to introduce our first generation red acetylcholine sensors! #acetylcholine #GRAB #RedSensors
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Red-shifted GRAB acetylcholine sensors for multiplex imaging in vivo
The neurotransmitter acetylcholine (ACh) is essential in both the central and peripheral nervous systems. Recent studies highlight the significance of interactions between ACh and various neuromodulat...
www.biorxiv.org
December 28, 2024 at 5:49 AM
(1/6) Excited to introduce our first generation red acetylcholine sensors! #acetylcholine #GRAB #RedSensors
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Eyal Rozenfeld
🎄PinkyCaMP- our christmas gift to you! 🎁: We are excited to present PinkyCaMP, the first mScarlet based calcium sensor with:
✨exceptional, brightness
✨phototability
✨and optogenetic compatability.
Check out our new preprint:
www.biorxiv.org/content/10.1...
✨exceptional, brightness
✨phototability
✨and optogenetic compatability.
Check out our new preprint:
www.biorxiv.org/content/10.1...
December 18, 2024 at 10:01 AM
🎄PinkyCaMP- our christmas gift to you! 🎁: We are excited to present PinkyCaMP, the first mScarlet based calcium sensor with:
✨exceptional, brightness
✨phototability
✨and optogenetic compatability.
Check out our new preprint:
www.biorxiv.org/content/10.1...
✨exceptional, brightness
✨phototability
✨and optogenetic compatability.
Check out our new preprint:
www.biorxiv.org/content/10.1...
Reposted by Eyal Rozenfeld
Apropos of never ending discussions about whether ANNs are "good" models of the nervous system, here is a slide I present to masters students showing a network that is found in motor control circuits *across phyla* (that's pretty ubiquitous!) I ask them to guess what it does...
December 17, 2024 at 2:14 PM
Apropos of never ending discussions about whether ANNs are "good" models of the nervous system, here is a slide I present to masters students showing a network that is found in motor control circuits *across phyla* (that's pretty ubiquitous!) I ask them to guess what it does...
Reposted by Eyal Rozenfeld
Why not joining us?
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
December 16, 2024 at 10:51 PM
Why not joining us?
Reposted by Eyal Rozenfeld
Wanna switch on/off synaptic transmission but not the ideal vector for your🧠🧪🔬, we are happy to help!
Requested recently & available to you:
ChrimsonR(no soma targeting)+PdCO (Cre & non-Cre)
DoxOn/OFF PdCO-EGFP (TREtight)
-> docs.google.com/spreadsheets...
Probably soon @addgene.bsky.social too.
Requested recently & available to you:
ChrimsonR(no soma targeting)+PdCO (Cre & non-Cre)
DoxOn/OFF PdCO-EGFP (TREtight)
-> docs.google.com/spreadsheets...
Probably soon @addgene.bsky.social too.
December 16, 2024 at 11:35 AM
Wanna switch on/off synaptic transmission but not the ideal vector for your🧠🧪🔬, we are happy to help!
Requested recently & available to you:
ChrimsonR(no soma targeting)+PdCO (Cre & non-Cre)
DoxOn/OFF PdCO-EGFP (TREtight)
-> docs.google.com/spreadsheets...
Probably soon @addgene.bsky.social too.
Requested recently & available to you:
ChrimsonR(no soma targeting)+PdCO (Cre & non-Cre)
DoxOn/OFF PdCO-EGFP (TREtight)
-> docs.google.com/spreadsheets...
Probably soon @addgene.bsky.social too.
Reposted by Eyal Rozenfeld
Sex or survival—what’s more important? Excited to share our
@Nature paper on how flies resolve this conflict.
We found a dopamine-based filter that reduces threat perception, helping flies focus on courtship when close to mating.
www.nature.com/articles/s41...
@Nature paper on how flies resolve this conflict.
We found a dopamine-based filter that reduces threat perception, helping flies focus on courtship when close to mating.
www.nature.com/articles/s41...
Mating proximity blinds threat perception - Nature
A state-dependent dopamine filter system in the male Drosophila brain balances threat perception against the drive to mate.
www.nature.com
November 15, 2024 at 7:15 PM
Sex or survival—what’s more important? Excited to share our
@Nature paper on how flies resolve this conflict.
We found a dopamine-based filter that reduces threat perception, helping flies focus on courtship when close to mating.
www.nature.com/articles/s41...
@Nature paper on how flies resolve this conflict.
We found a dopamine-based filter that reduces threat perception, helping flies focus on courtship when close to mating.
www.nature.com/articles/s41...
Reposted by Eyal Rozenfeld
Hi everyone!
I am Daniela, a pre-clinical psychedelic researcher doing a PhD at the Paris Brain Institute under the supervision of Eric Burguière. I am working with the SAPAP3-KO mice and LSD.
I am a great advocate for open science, diversity and science communication!
Nice to meet you all 🥰
I am Daniela, a pre-clinical psychedelic researcher doing a PhD at the Paris Brain Institute under the supervision of Eric Burguière. I am working with the SAPAP3-KO mice and LSD.
I am a great advocate for open science, diversity and science communication!
Nice to meet you all 🥰
December 15, 2024 at 1:02 PM
Hi everyone!
I am Daniela, a pre-clinical psychedelic researcher doing a PhD at the Paris Brain Institute under the supervision of Eric Burguière. I am working with the SAPAP3-KO mice and LSD.
I am a great advocate for open science, diversity and science communication!
Nice to meet you all 🥰
I am Daniela, a pre-clinical psychedelic researcher doing a PhD at the Paris Brain Institute under the supervision of Eric Burguière. I am working with the SAPAP3-KO mice and LSD.
I am a great advocate for open science, diversity and science communication!
Nice to meet you all 🥰
Reposted by Eyal Rozenfeld
Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube!
Please like and repost to help us get the word out!
www.youtube.com/playlist?lis...
Lecture 1: Signals and data acquisition
Focusing on hardware, digital/analog I/O, synchronization
🧵
Please like and repost to help us get the word out!
www.youtube.com/playlist?lis...
Lecture 1: Signals and data acquisition
Focusing on hardware, digital/analog I/O, synchronization
🧵
Neuroscience methods - YouTube
Nanocourse: Approaches to Study Neural Circuits This course was taught by Anita Autry, Tiago Gonçalves, and Luke Sjulson at Albert Einstein College of Medici...
www.youtube.com
December 13, 2024 at 11:33 AM
Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube!
Please like and repost to help us get the word out!
www.youtube.com/playlist?lis...
Lecture 1: Signals and data acquisition
Focusing on hardware, digital/analog I/O, synchronization
🧵
Please like and repost to help us get the word out!
www.youtube.com/playlist?lis...
Lecture 1: Signals and data acquisition
Focusing on hardware, digital/analog I/O, synchronization
🧵
Reposted by Eyal Rozenfeld
I made the Insect Sensory Neuro starter pack - let me know in the comments if you'd like to be added! (and also I'm sure I missed tons of people - tag them in!)
go.bsky.app/JW7c5LN
go.bsky.app/JW7c5LN
December 1, 2024 at 11:06 PM
I made the Insect Sensory Neuro starter pack - let me know in the comments if you'd like to be added! (and also I'm sure I missed tons of people - tag them in!)
go.bsky.app/JW7c5LN
go.bsky.app/JW7c5LN