Tal Laviv
@lavivtal.bsky.social
Neuroscientists, microscopy, biosensors
www.lavivlab.com
www.lavivlab.com
I started my lab more then 4 years ago, and we have endured some very challenging times ever since.…I am very excited to share the first paper from my lab, published now in @naturemethods.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Genetically encoded biosensor for fluorescence lifetime imaging of PTEN dynamics in the intact brain - Nature Methods
A first-in-class fluorescence lifetime-based FRET sensor for phosphatase and tensin homolog (PTEN) enables the dynamic monitoring of PTEN activity in cultured cells and in vivo with high spatiotempora...
www.nature.com
February 20, 2025 at 1:10 PM
I started my lab more then 4 years ago, and we have endured some very challenging times ever since.…I am very excited to share the first paper from my lab, published now in @naturemethods.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Tal Laviv
Yesterday, we held the 2024 Sieratzki Prizes Ceremony at the ISFN meeting in Eilat. We are so proud of our 2024 winners: @yoavlivneh.bsky.social , Arseny Finkelstein, David Omer, @lavivtal.bsky.social, and Inbal Ben-Ami Bartal!
January 15, 2025 at 9:27 PM
Yesterday, we held the 2024 Sieratzki Prizes Ceremony at the ISFN meeting in Eilat. We are so proud of our 2024 winners: @yoavlivneh.bsky.social , Arseny Finkelstein, David Omer, @lavivtal.bsky.social, and Inbal Ben-Ami Bartal!
Reposted by Tal Laviv
How to improve memory and cognitive function in aged mice
Fix the mitochondrial EC (excitation-coupling)
@science.org
representing a new potential path for replenishing neuronal energy reserves to counter brain aging
www.science.org/doi/10.1126/...
Fix the mitochondrial EC (excitation-coupling)
@science.org
representing a new potential path for replenishing neuronal energy reserves to counter brain aging
www.science.org/doi/10.1126/...
December 19, 2024 at 10:57 PM
How to improve memory and cognitive function in aged mice
Fix the mitochondrial EC (excitation-coupling)
@science.org
representing a new potential path for replenishing neuronal energy reserves to counter brain aging
www.science.org/doi/10.1126/...
Fix the mitochondrial EC (excitation-coupling)
@science.org
representing a new potential path for replenishing neuronal energy reserves to counter brain aging
www.science.org/doi/10.1126/...
Beautiful work by my the lab of Huan Ma, which I had the pleasure to contribute to. A fascinating link between neuronal activity, and transcription-excitation coupling in mitochodria to brain function and ageing www.science.org/doi/10.1126/...
Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in aged mice
Deciphering the complex interplay between neuronal activity and mitochondrial function is pivotal in understanding brain aging, a multifaceted process marked by declines in synaptic function and mitoc...
www.science.org
December 20, 2024 at 6:20 AM
Beautiful work by my the lab of Huan Ma, which I had the pleasure to contribute to. A fascinating link between neuronal activity, and transcription-excitation coupling in mitochodria to brain function and ageing www.science.org/doi/10.1126/...
Hello there! My first try here:
Sharing an in vivo image of a beautiful dendrite with a GFP knock-in to endogenous CaMKIIa
Sharing an in vivo image of a beautiful dendrite with a GFP knock-in to endogenous CaMKIIa
November 16, 2024 at 4:05 PM
Hello there! My first try here:
Sharing an in vivo image of a beautiful dendrite with a GFP knock-in to endogenous CaMKIIa
Sharing an in vivo image of a beautiful dendrite with a GFP knock-in to endogenous CaMKIIa
Reposted by Tal Laviv
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy
RNA splicing enables the functional adaptation of cells to changing contexts. Impaired splicing has been associated with diseases, including retinitis pigmentosa, but the underlying molecular mechanis...
www.science.org
November 15, 2024 at 11:59 AM
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Tal Laviv
I'm very happy with how this image turned out and can't even wait for #FluorescenceFriday! I'm trying to detect Tau protein phosphorylation before forming full fibrillary tangles in #Alzheimer disease. Healthy neurons: (🟠NeuN), Dying neurons: pTau ( 🟣422), (🔵AT8). More info in the Alt tex! 🧠🔬
November 14, 2024 at 9:41 PM
I'm very happy with how this image turned out and can't even wait for #FluorescenceFriday! I'm trying to detect Tau protein phosphorylation before forming full fibrillary tangles in #Alzheimer disease. Healthy neurons: (🟠NeuN), Dying neurons: pTau ( 🟣422), (🔵AT8). More info in the Alt tex! 🧠🔬