EUROSERPIN
@euroserpin.bsky.social
A network of biomedical researchers with an interest in the biology of serpins, their protease and ligand targets, and the pathways they regulate.
Pinned
EUROSERPIN
@euroserpin.bsky.social
· Jan 29
We are pleased to announce #EUROSERPIN2025, to be held in Brescia, Italy on May 28-30th 2025! This meeting will bring together international researchers to share their work on all aspects of serpin-related topics. Visit euroserpin.eu to register and submit an abstract.
The EUROSERPIN2025 meeting, held at the Cloister of San Faustino, University of Brescia, has just ended. Thanks to all participants, speakers, poster presenters and to the University of Brescia. We can't wait for the next EUROSERPIN meeting!
June 4, 2025 at 11:05 AM
The EUROSERPIN2025 meeting, held at the Cloister of San Faustino, University of Brescia, has just ended. Thanks to all participants, speakers, poster presenters and to the University of Brescia. We can't wait for the next EUROSERPIN meeting!
Reposted by EUROSERPIN
We're welcoming a new cohort of PhD students to the
Vienna BioCenter PhD program from various universities around the world. Our Spring call with 25+ fully-funded PhD positions in the life sciences is now open: vbcphd.at
@viennabiocenter.bsky.social @vbcscitraining.bsky.social
Vienna BioCenter PhD program from various universities around the world. Our Spring call with 25+ fully-funded PhD positions in the life sciences is now open: vbcphd.at
@viennabiocenter.bsky.social @vbcscitraining.bsky.social
March 26, 2025 at 1:13 PM
We're welcoming a new cohort of PhD students to the
Vienna BioCenter PhD program from various universities around the world. Our Spring call with 25+ fully-funded PhD positions in the life sciences is now open: vbcphd.at
@viennabiocenter.bsky.social @vbcscitraining.bsky.social
Vienna BioCenter PhD program from various universities around the world. Our Spring call with 25+ fully-funded PhD positions in the life sciences is now open: vbcphd.at
@viennabiocenter.bsky.social @vbcscitraining.bsky.social
Reposted by EUROSERPIN
Tandem duplication of serpin genes yields functional variation and snake venom inhibitors. https://www.biorxiv.org/content/10.1101/2025.01.07.631777v1
January 10, 2025 at 9:33 PM
Tandem duplication of serpin genes yields functional variation and snake venom inhibitors. https://www.biorxiv.org/content/10.1101/2025.01.07.631777v1
Reposted by EUROSERPIN
Excited to report our studies that identified a new serine protease secreted by the gut microbe Bacteroides fragilis that regulates pain and inflammation through PAR2 activation. #ChemBio. Check it out!https://www.biorxiv.org/content/10.1101/2025.01.15.633241v1
Identification of a secreted protease from Bacteroides fragilis that induces intestinal pain and inflammation by cleavage of PAR2
Protease-activated receptor 2 (PAR2) is a central regulator of intestinal barrier function, inflammation and pain. Upregulated intestinal proteolysis and PAR2-signaling are implicated in inflammatory ...
www.biorxiv.org
January 16, 2025 at 5:11 PM
Excited to report our studies that identified a new serine protease secreted by the gut microbe Bacteroides fragilis that regulates pain and inflammation through PAR2 activation. #ChemBio. Check it out!https://www.biorxiv.org/content/10.1101/2025.01.15.633241v1
Reposted by EUROSERPIN
Rare disease research relies on collecting genomic and clinical data across multiple countries.
Learn more about the Solve-RD project and how it aims to collect and harmonise #raredisease data across multiple European partners.
🧬🖥️
www.ebi.ac.uk/about/news/a...
Learn more about the Solve-RD project and how it aims to collect and harmonise #raredisease data across multiple European partners.
🧬🖥️
www.ebi.ac.uk/about/news/a...
Solve-RD: supporting rare disease data collection and harmonisation
The Solve-RD project standardises genomic and clinical data across Europe to support rare disease research.
www.ebi.ac.uk
January 28, 2025 at 10:19 AM
Rare disease research relies on collecting genomic and clinical data across multiple countries.
Learn more about the Solve-RD project and how it aims to collect and harmonise #raredisease data across multiple European partners.
🧬🖥️
www.ebi.ac.uk/about/news/a...
Learn more about the Solve-RD project and how it aims to collect and harmonise #raredisease data across multiple European partners.
🧬🖥️
www.ebi.ac.uk/about/news/a...
We are pleased to announce #EUROSERPIN2025, to be held in Brescia, Italy on May 28-30th 2025! This meeting will bring together international researchers to share their work on all aspects of serpin-related topics. Visit euroserpin.eu to register and submit an abstract.
January 29, 2025 at 9:55 PM
We are pleased to announce #EUROSERPIN2025, to be held in Brescia, Italy on May 28-30th 2025! This meeting will bring together international researchers to share their work on all aspects of serpin-related topics. Visit euroserpin.eu to register and submit an abstract.
Reposted by EUROSERPIN
A bit of microscopy to get me off the mark! Single particle tracking of fluorescent, 20nm spherical protein assemblies (GEMs) as they dance through the ER-lumen of a COS7 cell. One of the tools we used to assess ER-biophysics in α1-antitrypsin deficiency science.org/doi/10.1126/sciadv.abm2094
November 13, 2024 at 1:59 PM
A bit of microscopy to get me off the mark! Single particle tracking of fluorescent, 20nm spherical protein assemblies (GEMs) as they dance through the ER-lumen of a COS7 cell. One of the tools we used to assess ER-biophysics in α1-antitrypsin deficiency science.org/doi/10.1126/sciadv.abm2094
Reposted by EUROSERPIN
#Anopheles gambiae SRPN18 crystal structure non-inhibitory serpin @Michel_Lab @IUCr http://scripts.iucr.org/cgi-bin/paper?S2053230X16017854
1.45 Å resolution structure of SRPN18 from the malaria ve...
The structure of the A. gambiae serine proteinase inhibit...
scripts.iucr.org
December 11, 2024 at 2:25 AM
#Anopheles gambiae SRPN18 crystal structure non-inhibitory serpin @Michel_Lab @IUCr http://scripts.iucr.org/cgi-bin/paper?S2053230X16017854
Reposted by EUROSERPIN
Unlike other serpins, human serpin B9 shows significant structural deviations around helix D, with a larger surface cavity, which could serve as a promising target for small-molecule inhibitors #Serpins #XRayCrystallography #Crystallization t.co/ilB7Aa3Krg
November 11, 2024 at 2:42 PM
Unlike other serpins, human serpin B9 shows significant structural deviations around helix D, with a larger surface cavity, which could serve as a promising target for small-molecule inhibitors #Serpins #XRayCrystallography #Crystallization t.co/ilB7Aa3Krg