Reposted by Euan Reid
Great to see Opioid Deprescribing highlighted in @nejm.org!
Opioid deprescribing through a tailored, patient-centered plan is recommended when the potential harms of opioid therapy outweigh the potential benefits.
Link to the article here:
nej.md/4oL3fu2
@sydney.edu.au
Opioid deprescribing through a tailored, patient-centered plan is recommended when the potential harms of opioid therapy outweigh the potential benefits.
Link to the article here:
nej.md/4oL3fu2
@sydney.edu.au
November 11, 2025 at 5:01 PM
Great to see Opioid Deprescribing highlighted in @nejm.org!
Opioid deprescribing through a tailored, patient-centered plan is recommended when the potential harms of opioid therapy outweigh the potential benefits.
Link to the article here:
nej.md/4oL3fu2
@sydney.edu.au
Opioid deprescribing through a tailored, patient-centered plan is recommended when the potential harms of opioid therapy outweigh the potential benefits.
Link to the article here:
nej.md/4oL3fu2
@sydney.edu.au
Reposted by Euan Reid
In the ATTAIN-1 phase 3, randomized trial, the use of orforglipron, an oral glucagon-like peptide-1 receptor agonist, led to significant mean body-weight reductions in patients with #obesity, as compared with placebo. Full trial results and Research Summary: nej.md/4n1nSl2
#MedSky #EndoSky
#MedSky #EndoSky
November 11, 2025 at 2:02 PM
In the ATTAIN-1 phase 3, randomized trial, the use of orforglipron, an oral glucagon-like peptide-1 receptor agonist, led to significant mean body-weight reductions in patients with #obesity, as compared with placebo. Full trial results and Research Summary: nej.md/4n1nSl2
#MedSky #EndoSky
#MedSky #EndoSky
Reposted by Euan Reid
"It outperformed semaglutide."
Scientists Say They've Figured Out a Way to Reprogram the Pancreas to Produce GLP-1s Without Ozempic
Scientists say they've come up with a way for the body to produce its own store of glucagon-like peptide-1 (GLP-1).
trib.al
November 10, 2025 at 3:41 PM
"It outperformed semaglutide."
Reposted by Euan Reid
Net spending on medicines grew by 11.4% in 2024 alone. In theory that ought to mean healthier people. But in practice, America spends more on health care than other rich countries without better outcomes
America’s health-care costs are shooting up
One big reason is that people are seeking more treatment
econ.st
November 10, 2025 at 10:00 AM
Net spending on medicines grew by 11.4% in 2024 alone. In theory that ought to mean healthier people. But in practice, America spends more on health care than other rich countries without better outcomes
Reposted by Euan Reid
The NHS sickness absence rate was 4.8% this April - similar to the previous year.
But that's still way above the public sector average, which has never crossed the 4% mark and was below 3% in 2024.
Read more about trends in NHS staffing, here: buff.ly/ed9ZKwK
But that's still way above the public sector average, which has never crossed the 4% mark and was below 3% in 2024.
Read more about trends in NHS staffing, here: buff.ly/ed9ZKwK
November 10, 2025 at 12:18 PM
The NHS sickness absence rate was 4.8% this April - similar to the previous year.
But that's still way above the public sector average, which has never crossed the 4% mark and was below 3% in 2024.
Read more about trends in NHS staffing, here: buff.ly/ed9ZKwK
But that's still way above the public sector average, which has never crossed the 4% mark and was below 3% in 2024.
Read more about trends in NHS staffing, here: buff.ly/ed9ZKwK
Reposted by Euan Reid
No clear evidence to support any link between maternal acetaminophen (Tylenol) intake and autism or ADHD in offspring, a new umbrella, systematic review
@bmj.com
@bmj.com
November 10, 2025 at 12:19 AM
No clear evidence to support any link between maternal acetaminophen (Tylenol) intake and autism or ADHD in offspring, a new umbrella, systematic review
@bmj.com
@bmj.com
Reposted by Euan Reid
A new analysis of the SELECT trial confirms semaglutide lowers the risk of major heart problems in people who are overweight or obese and already have heart disease, even if they don’t have diabetes.
Explore the research 👉 tinyurl.com/bxw4cmtt
Explore the research 👉 tinyurl.com/bxw4cmtt
Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial
The cardioprotective effects of semaglutide were independent of baseline adiposity
and weight loss and had only a small association with waist circumference, suggesting
some mechanisms for benefit bey...
tinyurl.com
October 23, 2025 at 9:50 AM
A new analysis of the SELECT trial confirms semaglutide lowers the risk of major heart problems in people who are overweight or obese and already have heart disease, even if they don’t have diabetes.
Explore the research 👉 tinyurl.com/bxw4cmtt
Explore the research 👉 tinyurl.com/bxw4cmtt
Reposted by Euan Reid
Nature research paper: SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade
go.nature.com/477I3sj
go.nature.com/477I3sj
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade - Nature
mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.
go.nature.com
October 28, 2025 at 11:53 AM
Nature research paper: SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade
go.nature.com/477I3sj
go.nature.com/477I3sj
Reposted by Euan Reid
New BMJ Research: Greenness and hospital admissions for cause specific mental disorders.
Study finds that local greenness was associated with a 7% reduction in hospital admissions for all cause mental disorders
#BMJClimate
www.bmj.com/content/391/...
Study finds that local greenness was associated with a 7% reduction in hospital admissions for all cause mental disorders
#BMJClimate
www.bmj.com/content/391/...
November 6, 2025 at 8:37 AM
New BMJ Research: Greenness and hospital admissions for cause specific mental disorders.
Study finds that local greenness was associated with a 7% reduction in hospital admissions for all cause mental disorders
#BMJClimate
www.bmj.com/content/391/...
Study finds that local greenness was associated with a 7% reduction in hospital admissions for all cause mental disorders
#BMJClimate
www.bmj.com/content/391/...
iSIMPATHY: a multinational pre–post non-randomised intervention study transforming medication review
#Pharmsky
bmjopen.bmj.com/content/15/1...
#Pharmsky
bmjopen.bmj.com/content/15/1...
iSIMPATHY: a multinational pre–post non-randomised intervention study transforming medication review
Background Taking multiple medicines can be appropriate but has the potential to be problematic. The Implementing Stimulating Innovation in the Management of Polypharmacy and Adherence THrough the Yea...
bmjopen.bmj.com
November 9, 2025 at 8:32 AM
iSIMPATHY: a multinational pre–post non-randomised intervention study transforming medication review
#Pharmsky
bmjopen.bmj.com/content/15/1...
#Pharmsky
bmjopen.bmj.com/content/15/1...
Reposted by Euan Reid
In patients with atrial fibrillation after successful ablation, rivaroxaban therapy did not lead to a significantly lower incidence of a composite of stroke, systemic embolism, or new covert embolic stroke than aspirin therapy. Full OCEAN trial results: nej.md/3LsRJ86
#AHA25
#AHA25
November 8, 2025 at 8:20 PM
In patients with atrial fibrillation after successful ablation, rivaroxaban therapy did not lead to a significantly lower incidence of a composite of stroke, systemic embolism, or new covert embolic stroke than aspirin therapy. Full OCEAN trial results: nej.md/3LsRJ86
#AHA25
#AHA25
Changes to the Scottish Childhood Vaccination Schedule from 1 January 2026 (phase 2) – introduction of a routine Varicella Zoster (Chickenpox) vaccine following expert advice from the JCVI published in November 2023. 🏴 #Pharmsky
www.publications.scot.nhs.uk/publication/...
www.publications.scot.nhs.uk/publication/...
November 8, 2025 at 8:49 AM
Changes to the Scottish Childhood Vaccination Schedule from 1 January 2026 (phase 2) – introduction of a routine Varicella Zoster (Chickenpox) vaccine following expert advice from the JCVI published in November 2023. 🏴 #Pharmsky
www.publications.scot.nhs.uk/publication/...
www.publications.scot.nhs.uk/publication/...
Reposted by Euan Reid
An encouraging new study by @publichealthscot.bsky.social, in collaboration with the University of Edinburgh and @unistrathclyde.bsky.social, confirms the HPV vaccine provides strong and sustained protection against cervical disease that can develop into cancer.
edin.ac/47zVAYn
edin.ac/47zVAYn
November 4, 2025 at 10:00 AM
An encouraging new study by @publichealthscot.bsky.social, in collaboration with the University of Edinburgh and @unistrathclyde.bsky.social, confirms the HPV vaccine provides strong and sustained protection against cervical disease that can develop into cancer.
edin.ac/47zVAYn
edin.ac/47zVAYn
Reposted by Euan Reid
Ozempic and Zepbound are just the beginning of the expanded medical GI hormone era. A new selective amylin mimetic (pancreatic peptide)) achieved marked weight loss and reduced inflammation without a plateau effect in a randomized trial
@thelancet.com
thelancet.com/journals/lan...
@thelancet.com
thelancet.com/journals/lan...
November 7, 2025 at 2:24 PM
Ozempic and Zepbound are just the beginning of the expanded medical GI hormone era. A new selective amylin mimetic (pancreatic peptide)) achieved marked weight loss and reduced inflammation without a plateau effect in a randomized trial
@thelancet.com
thelancet.com/journals/lan...
@thelancet.com
thelancet.com/journals/lan...
Reposted by Euan Reid
A new report from the independent #ADHD Taskforce, which our Chief Exec @theasrstein.bsky.social sits on, has been published today.
Read here: buff.ly/d61LdPh
Our #QualityWatch programme is also tracking how the rise in demand for ADHD support can be seen through prescribing data: buff.ly/BejmNAQ
Read here: buff.ly/d61LdPh
Our #QualityWatch programme is also tracking how the rise in demand for ADHD support can be seen through prescribing data: buff.ly/BejmNAQ
November 6, 2025 at 1:44 PM
A new report from the independent #ADHD Taskforce, which our Chief Exec @theasrstein.bsky.social sits on, has been published today.
Read here: buff.ly/d61LdPh
Our #QualityWatch programme is also tracking how the rise in demand for ADHD support can be seen through prescribing data: buff.ly/BejmNAQ
Read here: buff.ly/d61LdPh
Our #QualityWatch programme is also tracking how the rise in demand for ADHD support can be seen through prescribing data: buff.ly/BejmNAQ
Reposted by Euan Reid
Not all medicines are equal
⏱️ Some need to be taken at a certain time
🍽️ Some need to be taken with food
🍂 Some may interact with herbal remedies
#MedSafetyWeek
⏱️ Some need to be taken at a certain time
🍽️ Some need to be taken with food
🍂 Some may interact with herbal remedies
#MedSafetyWeek
November 6, 2025 at 4:07 PM
Not all medicines are equal
⏱️ Some need to be taken at a certain time
🍽️ Some need to be taken with food
🍂 Some may interact with herbal remedies
#MedSafetyWeek
⏱️ Some need to be taken at a certain time
🍽️ Some need to be taken with food
🍂 Some may interact with herbal remedies
#MedSafetyWeek
Reposted by Euan Reid
The #NHSProductivityCommission has published its first major report, setting out the scale of the productivity challenge within the NHS and highlighting key drivers for and barriers to improving productivity.
Read more ⬇️
https://bit.ly/3WBvBef
Read more ⬇️
https://bit.ly/3WBvBef
November 5, 2025 at 2:35 PM
The #NHSProductivityCommission has published its first major report, setting out the scale of the productivity challenge within the NHS and highlighting key drivers for and barriers to improving productivity.
Read more ⬇️
https://bit.ly/3WBvBef
Read more ⬇️
https://bit.ly/3WBvBef
Reposted by Euan Reid
Many clinical studies have shown reduced cancer risk in people with diabetes of obesity taking GLP-1 family of drugs. A new JCI piece makes the case these drugs should be studied to reduce cancer in people without metabolic disease jci.org/articles/vie...
November 3, 2025 at 7:08 PM
Many clinical studies have shown reduced cancer risk in people with diabetes of obesity taking GLP-1 family of drugs. A new JCI piece makes the case these drugs should be studied to reduce cancer in people without metabolic disease jci.org/articles/vie...
Reposted by Euan Reid
Intriguing study from @thelancet.com finds #deprescribing sleep medications in adults over age 50 could:
📉 Reduce the lifetime incidence of falls by 8.5% & cognitive impairment by 2.1%
📈 Increase life expectancy by 0.11 years
💵 Result in net lifetime savings of $6,600 per person
buff.ly/515uJ9s
📉 Reduce the lifetime incidence of falls by 8.5% & cognitive impairment by 2.1%
📈 Increase life expectancy by 0.11 years
💵 Result in net lifetime savings of $6,600 per person
buff.ly/515uJ9s
October 31, 2025 at 4:02 PM
Intriguing study from @thelancet.com finds #deprescribing sleep medications in adults over age 50 could:
📉 Reduce the lifetime incidence of falls by 8.5% & cognitive impairment by 2.1%
📈 Increase life expectancy by 0.11 years
💵 Result in net lifetime savings of $6,600 per person
buff.ly/515uJ9s
📉 Reduce the lifetime incidence of falls by 8.5% & cognitive impairment by 2.1%
📈 Increase life expectancy by 0.11 years
💵 Result in net lifetime savings of $6,600 per person
buff.ly/515uJ9s
Reposted by Euan Reid
(1/3) Today is the start of #MedSafetyWeek. Unsafe medication practices and medication-related harm are one of the leading causes of avoidable harm in health and care. This year's event is focused on the theme "we can all help make medicines safer".
November 3, 2025 at 8:18 AM
(1/3) Today is the start of #MedSafetyWeek. Unsafe medication practices and medication-related harm are one of the leading causes of avoidable harm in health and care. This year's event is focused on the theme "we can all help make medicines safer".
Reposted by Euan Reid
GLP-1 drugs have intrinsic potent anti-inflammatory action beyond their metabolic beneficial impact on glucose regulation and weight loss
www.jci.org/articles/vie...
www.jci.org/articles/vie...
November 3, 2025 at 5:20 PM
GLP-1 drugs have intrinsic potent anti-inflammatory action beyond their metabolic beneficial impact on glucose regulation and weight loss
www.jci.org/articles/vie...
www.jci.org/articles/vie...
Hospital at Home | Guiding principles for service development 🏴
www.healthcareimprovementscotland.scot/wp-content/u...
www.healthcareimprovementscotland.scot/wp-content/u...
November 2, 2025 at 8:04 AM
Hospital at Home | Guiding principles for service development 🏴
www.healthcareimprovementscotland.scot/wp-content/u...
www.healthcareimprovementscotland.scot/wp-content/u...
Reposted by Euan Reid
The benefit of Ozempic (semaglutide) for protection from major adverse cardiovascular events (MACE) is independent of weight loss magnitude and baseline adiposity, likely related to the GLP-1 anti-inflammatory effect
thelancet.com/journals/lan...
thelancet.com/journals/lan...
Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial
The cardioprotective effects of semaglutide were independent of baseline adiposity
and weight loss and had only a small association with waist circumference, suggesting
some mechanisms for benefit bey...
thelancet.com
October 22, 2025 at 10:43 PM
The benefit of Ozempic (semaglutide) for protection from major adverse cardiovascular events (MACE) is independent of weight loss magnitude and baseline adiposity, likely related to the GLP-1 anti-inflammatory effect
thelancet.com/journals/lan...
thelancet.com/journals/lan...
Reposted by Euan Reid
Exposure to sugar early in life: a natural experiment among >63,000 @uk_biobank participants: rationing of sugar was associated with less cardiovascular risk in adulthood www.bmj.com/content/391/...
Exposure to sugar rationing in first 1000 days after conception and long term cardiovascular outcomes: natural experiment study
Objective To examine whether exposure to sugar rationing during early life is associated with a reduction in the risk of cardiovascular outcomes in adulthood.
Design Natural experiment study.
Settin...
www.bmj.com
October 23, 2025 at 12:44 AM
Exposure to sugar early in life: a natural experiment among >63,000 @uk_biobank participants: rationing of sugar was associated with less cardiovascular risk in adulthood www.bmj.com/content/391/...
Reposted by Euan Reid
Longer walks linked with less mortality and cardiovascular risk compared with short bouts of physical activity
@annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...
@annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...
Step Accumulation Patterns and Risk for Cardiovascular Events and Mortality Among Suboptimally Active Adults | Annals of Internal Medicine
Background: Although physical activity recommendations increasingly consider daily step counts, it remains unclear whether step accumulation patterns—short versus sustained longer bouts—affect associa...
www.acpjournals.org
October 28, 2025 at 7:29 AM
Longer walks linked with less mortality and cardiovascular risk compared with short bouts of physical activity
@annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...
@annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...