Reposted by Euan Reid
Continuous glucose monitoring sensor data, with a foundation model, predicts risk of Type 2 diabetes and cardiovascular outcomes better than HbA1c
New @nature.com
www.nature.com/articles/s41...
New @nature.com
www.nature.com/articles/s41...
January 14, 2026 at 4:39 PM
Continuous glucose monitoring sensor data, with a foundation model, predicts risk of Type 2 diabetes and cardiovascular outcomes better than HbA1c
New @nature.com
www.nature.com/articles/s41...
New @nature.com
www.nature.com/articles/s41...
Reposted by Euan Reid
January 13, 2026 at 11:10 AM
Reposted by Euan Reid
And reduction of sedentary time by 30 minutes/day was also associated with a significant mortality benefit, albeit less than the increase in physical activity
January 13, 2026 at 11:58 PM
And reduction of sedentary time by 30 minutes/day was also associated with a significant mortality benefit, albeit less than the increase in physical activity
Reposted by Euan Reid
Just 5 extra minutes per day of walking at an average speed is linked to a 10% reduction in deaths, from a meta-analysis of 135,000 participants in 7 cohorts (Norway, Sweden, and the US)
New @thelancet.com
thelancet.com/journals/lan...
New @thelancet.com
thelancet.com/journals/lan...
Deaths potentially averted by small changes in physical activity and sedentary time: an individual participant data meta-analysis of prospective cohort studies
Small and realistic increases in MVPA of 5 min/day might prevent up to 6% of all deaths
in a high-risk approach and 10% of all deaths in population-based approach. Reducing
sedentary time by 30 min/da...
thelancet.com
January 13, 2026 at 11:57 PM
Just 5 extra minutes per day of walking at an average speed is linked to a 10% reduction in deaths, from a meta-analysis of 135,000 participants in 7 cohorts (Norway, Sweden, and the US)
New @thelancet.com
thelancet.com/journals/lan...
New @thelancet.com
thelancet.com/journals/lan...
Reposted by Euan Reid
💡 In older adults, deprescribing benzodiazepines is associated with a reduced mortality risk (-41%) 6 months post-hospitalisation.
Those RXed BZDs at discharge had a x1.64 higher risk of all-cause mortality than BZD non-users.
🔗 Read the full research paper here: tinyurl.com/n4skbst3
Those RXed BZDs at discharge had a x1.64 higher risk of all-cause mortality than BZD non-users.
🔗 Read the full research paper here: tinyurl.com/n4skbst3
Benzodiazepine exposure and 6-month mortality in older adults post-hospitalization: time to consider deprescribing?
AbstractBackground. Benzodiazepines (BZDs) are commonly used in older populations despite their association with multiple adverse outcomes. However, the im
tinyurl.com
January 13, 2026 at 3:57 PM
💡 In older adults, deprescribing benzodiazepines is associated with a reduced mortality risk (-41%) 6 months post-hospitalisation.
Those RXed BZDs at discharge had a x1.64 higher risk of all-cause mortality than BZD non-users.
🔗 Read the full research paper here: tinyurl.com/n4skbst3
Those RXed BZDs at discharge had a x1.64 higher risk of all-cause mortality than BZD non-users.
🔗 Read the full research paper here: tinyurl.com/n4skbst3
Reposted by Euan Reid
The role of pharmacists in geriatric #care: current evidence and practice
#Pharmacy #Pharmacology #Geriatrics #Frailty #Aging #MedSky
link.springer.com/article/10.1...
#Pharmacy #Pharmacology #Geriatrics #Frailty #Aging #MedSky
link.springer.com/article/10.1...
Client Challenge
link.springer.com
January 14, 2026 at 6:44 AM
The role of pharmacists in geriatric #care: current evidence and practice
#Pharmacy #Pharmacology #Geriatrics #Frailty #Aging #MedSky
link.springer.com/article/10.1...
#Pharmacy #Pharmacology #Geriatrics #Frailty #Aging #MedSky
link.springer.com/article/10.1...
Reposted by Euan Reid
Fascinating piece about how the fear of microplastics is almost certainly overblown.
One takeaway for me is that even the scientists behind the microplastics=bad papers are VERY reserved about whether these findings are really problematic.
www.theguardian.com/environment/...
One takeaway for me is that even the scientists behind the microplastics=bad papers are VERY reserved about whether these findings are really problematic.
www.theguardian.com/environment/...
‘A bombshell’: doubt cast on discovery of microplastics throughout human body
Exclusive: Some scientists say many detections are most likely error, with one high-profile study called a ‘joke’
www.theguardian.com
January 14, 2026 at 1:51 AM
Fascinating piece about how the fear of microplastics is almost certainly overblown.
One takeaway for me is that even the scientists behind the microplastics=bad papers are VERY reserved about whether these findings are really problematic.
www.theguardian.com/environment/...
One takeaway for me is that even the scientists behind the microplastics=bad papers are VERY reserved about whether these findings are really problematic.
www.theguardian.com/environment/...
Reposted by Euan Reid
www.rcgp.org.uk/representing.... Great to see this from @rcgp.bsky.social The @healthinnovnet.bsky.social Polypharmacy programme has lots of resources and education to support GPs, pharmacists and others to deliver high quality SMRs to patients taking multiple medicines.
Structured Medicines Review
This policy statement highlights the essential role of structured medication reviews in improving patient safety, reducing harm and supporting more sustainable use of medicines, particularly for peopl...
www.rcgp.org.uk
January 14, 2026 at 11:14 AM
www.rcgp.org.uk/representing.... Great to see this from @rcgp.bsky.social The @healthinnovnet.bsky.social Polypharmacy programme has lots of resources and education to support GPs, pharmacists and others to deliver high quality SMRs to patients taking multiple medicines.
Reposted by Euan Reid
In the phase 3 ACHIEVE-1 trial, published in June 2025, the oral small-molecule GLP-1 receptor agonist orforglipron significantly reduced the glycated hemoglobin level over a period of 40 weeks in adults with early type 2 diabetes. Download the Notable Articles of 2025: nej.md/49td1Lq
January 12, 2026 at 5:21 PM
In the phase 3 ACHIEVE-1 trial, published in June 2025, the oral small-molecule GLP-1 receptor agonist orforglipron significantly reduced the glycated hemoglobin level over a period of 40 weeks in adults with early type 2 diabetes. Download the Notable Articles of 2025: nej.md/49td1Lq
Reposted by Euan Reid
🔍 Check out the latest addition to our Deprescribing Guidelines Repository (DEPOT)!
"The Joint Clinical Practice Guideline on Benzodiazepine Tapering" from the American Society of Addiction Medicine provides comprehensive benzodiazepine tapering guidance.
Read more here:
buff.ly/TJOQUBw
"The Joint Clinical Practice Guideline on Benzodiazepine Tapering" from the American Society of Addiction Medicine provides comprehensive benzodiazepine tapering guidance.
Read more here:
buff.ly/TJOQUBw
January 12, 2026 at 5:02 PM
🔍 Check out the latest addition to our Deprescribing Guidelines Repository (DEPOT)!
"The Joint Clinical Practice Guideline on Benzodiazepine Tapering" from the American Society of Addiction Medicine provides comprehensive benzodiazepine tapering guidance.
Read more here:
buff.ly/TJOQUBw
"The Joint Clinical Practice Guideline on Benzodiazepine Tapering" from the American Society of Addiction Medicine provides comprehensive benzodiazepine tapering guidance.
Read more here:
buff.ly/TJOQUBw
Reposted by Euan Reid
Statistically significant does not mean clinically significant. In the latest Stats, Stat! animated video from 𝘕𝘌𝘑𝘔 𝘌𝘷𝘪𝘥𝘦𝘯𝘤𝘦, Nigam and colleagues explain the minimal clinically important difference.
Watch “How the Minimal Clinically Important Difference Works”: youtu.be/rStW1rBjURc
#MedSky
Watch “How the Minimal Clinically Important Difference Works”: youtu.be/rStW1rBjURc
#MedSky
January 11, 2026 at 5:01 PM
Statistically significant does not mean clinically significant. In the latest Stats, Stat! animated video from 𝘕𝘌𝘑𝘔 𝘌𝘷𝘪𝘥𝘦𝘯𝘤𝘦, Nigam and colleagues explain the minimal clinically important difference.
Watch “How the Minimal Clinically Important Difference Works”: youtu.be/rStW1rBjURc
#MedSky
Watch “How the Minimal Clinically Important Difference Works”: youtu.be/rStW1rBjURc
#MedSky
(Interim) revised Pharmacy Staffing Standards for Neonatal Services, produced by the Neonatal and Paediatric Pharmacist Group (NPPG) in conjunction with the Chief Paediatric Pharmacists Group (CPPG).
#Pharmsky
nppg.org.uk/neonatal-pha...
#Pharmsky
nppg.org.uk/neonatal-pha...
Neonatal Pharmacy Staffing Standards - NPPG
nppg.org.uk
January 9, 2026 at 9:32 AM
(Interim) revised Pharmacy Staffing Standards for Neonatal Services, produced by the Neonatal and Paediatric Pharmacist Group (NPPG) in conjunction with the Chief Paediatric Pharmacists Group (CPPG).
#Pharmsky
nppg.org.uk/neonatal-pha...
#Pharmsky
nppg.org.uk/neonatal-pha...
Drug Safety Update: Improving Information Supplied with Gabapentinoids (Pregabalin/Gabapentin), Benzodiazepines and Z-Drugs.
@mhragovuk.bsky.social
#Pharmsky
www.gov.uk/drug-safety-...
@mhragovuk.bsky.social
#Pharmsky
www.gov.uk/drug-safety-...
Improving Information Supplied with Gabapentinoids (Pregabalin/Gabapentin), Benzodiazepines and Z-Drugs
The MHRA has reviewed the warnings regarding addiction, dependence, withdrawal, and
tolerance for gabapentin, pregabalin, benzodiazepines, and z-drugs. The findings (detailed in the Public Assessment ...
www.gov.uk
January 9, 2026 at 9:29 AM
Drug Safety Update: Improving Information Supplied with Gabapentinoids (Pregabalin/Gabapentin), Benzodiazepines and Z-Drugs.
@mhragovuk.bsky.social
#Pharmsky
www.gov.uk/drug-safety-...
@mhragovuk.bsky.social
#Pharmsky
www.gov.uk/drug-safety-...
Reposted by Euan Reid
Delayed discharges affect people’s physical and mental health.
In 2024/25 people medically ready to leave spent 720,000 unnecessary days in hospital.
The Scottish Government and partners must improve how they evaluate initiatives to tackle delayed discharges: https://bit.ly/delayed_discharges
In 2024/25 people medically ready to leave spent 720,000 unnecessary days in hospital.
The Scottish Government and partners must improve how they evaluate initiatives to tackle delayed discharges: https://bit.ly/delayed_discharges
January 8, 2026 at 12:45 PM
Delayed discharges affect people’s physical and mental health.
In 2024/25 people medically ready to leave spent 720,000 unnecessary days in hospital.
The Scottish Government and partners must improve how they evaluate initiatives to tackle delayed discharges: https://bit.ly/delayed_discharges
In 2024/25 people medically ready to leave spent 720,000 unnecessary days in hospital.
The Scottish Government and partners must improve how they evaluate initiatives to tackle delayed discharges: https://bit.ly/delayed_discharges
Reposted by Euan Reid
Stopping weight loss drugs is followed by weight regain and reversal of beneficial effects on heart and metabolic health markers like high blood pressure, finds new BMJ Research.
Regain was faster than after behavioural weight management programmes
t.co/DOHTIlVzrE
Regain was faster than after behavioural weight management programmes
t.co/DOHTIlVzrE
January 8, 2026 at 9:44 AM
Stopping weight loss drugs is followed by weight regain and reversal of beneficial effects on heart and metabolic health markers like high blood pressure, finds new BMJ Research.
Regain was faster than after behavioural weight management programmes
t.co/DOHTIlVzrE
Regain was faster than after behavioural weight management programmes
t.co/DOHTIlVzrE
Reposted by Euan Reid
New paper from our team out over Christmas in BJCP
Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England
pubmed.ncbi.nlm.nih.gov/41406988/
Sometimes research becomes more relevant after you’ve written it 🧵
#medsky #haematology
Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England
pubmed.ncbi.nlm.nih.gov/41406988/
Sometimes research becomes more relevant after you’ve written it 🧵
#medsky #haematology
Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England - PubMed
The use of andexanet alfa varies markedly between NHS regions and between NHS trusts in England. This study is the first analysis of adoption of a new treatment using the OpenPrescribing Hospitals platform, which is expected to provide a generalizable framework for similar analyses in the future.
pubmed.ncbi.nlm.nih.gov
January 8, 2026 at 11:49 AM
New paper from our team out over Christmas in BJCP
Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England
pubmed.ncbi.nlm.nih.gov/41406988/
Sometimes research becomes more relevant after you’ve written it 🧵
#medsky #haematology
Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England
pubmed.ncbi.nlm.nih.gov/41406988/
Sometimes research becomes more relevant after you’ve written it 🧵
#medsky #haematology
Reposted by Euan Reid
🌍 Antihypertensives are among the commonly prescribed medications globally.
Read about a recently-published systematic review & meta-analysis on #deprescribing antihypertensive medications in older people, conducted together with our collaborators here:
buff.ly/CPznF05
Read about a recently-published systematic review & meta-analysis on #deprescribing antihypertensive medications in older people, conducted together with our collaborators here:
buff.ly/CPznF05
January 8, 2026 at 5:01 PM
🌍 Antihypertensives are among the commonly prescribed medications globally.
Read about a recently-published systematic review & meta-analysis on #deprescribing antihypertensive medications in older people, conducted together with our collaborators here:
buff.ly/CPznF05
Read about a recently-published systematic review & meta-analysis on #deprescribing antihypertensive medications in older people, conducted together with our collaborators here:
buff.ly/CPznF05
People with asthma could benefit from digital tools on their phones or tablets to help them better manage their condition, states our draft guidance published today.
www.nice.org.uk/news/article...
@nicecomms.bsky.social
#Pharmsky
www.nice.org.uk/news/article...
@nicecomms.bsky.social
#Pharmsky
Digital platforms recommended to help people manage their asthma
www.nice.org.uk
January 7, 2026 at 3:43 PM
People with asthma could benefit from digital tools on their phones or tablets to help them better manage their condition, states our draft guidance published today.
www.nice.org.uk/news/article...
@nicecomms.bsky.social
#Pharmsky
www.nice.org.uk/news/article...
@nicecomms.bsky.social
#Pharmsky
Reposted by Euan Reid
Designing a new drug generally starts by screening small organic molecules for promising biological activity and selecting the likeliest
AI can sift through libraries of tens of billions of these
AI can sift through libraries of tens of billions of these
An AI revolution in drugmaking is under way
It will transform how medicines are made—and the industry itself
econ.st
January 6, 2026 at 10:20 AM
Designing a new drug generally starts by screening small organic molecules for promising biological activity and selecting the likeliest
AI can sift through libraries of tens of billions of these
AI can sift through libraries of tens of billions of these
Government launches consultation to help combat rising drug deaths from opioids, as part of record £3.4 billion in investment in drug and alcohol services.
#Pharmsky
www.gov.uk/government/n...
#Pharmsky
www.gov.uk/government/n...
Lives to be saved by boosting access to drug overdose medication
Government launches consultation to help combat rising drug deaths from opioids, as part of record £3.4 billion in investment in drug and alcohol services.
www.gov.uk
December 31, 2025 at 9:37 AM
Government launches consultation to help combat rising drug deaths from opioids, as part of record £3.4 billion in investment in drug and alcohol services.
#Pharmsky
www.gov.uk/government/n...
#Pharmsky
www.gov.uk/government/n...
How medicines affect gut bacteria could inform safer, more effective use.
#Pharmsky
www.gov.uk/government/n...
#Pharmsky
www.gov.uk/government/n...
How medicines affect gut bacteria could inform safer, more effective use
Understanding gut microbiome interactions with medicines could help explain differences in how people respond to treatment and build on existing medicine safety knowledge to support safer, more effect...
www.gov.uk
December 31, 2025 at 8:01 AM
How medicines affect gut bacteria could inform safer, more effective use.
#Pharmsky
www.gov.uk/government/n...
#Pharmsky
www.gov.uk/government/n...
Reposted by Euan Reid
The @europeanrespsoc.bsky.social guidelines for the management of bronchiectasis in adults provide an evidence-based framework for the management of patients with bronchiectasis https://bit.ly/3VBk0eC
December 28, 2025 at 2:25 PM
The @europeanrespsoc.bsky.social guidelines for the management of bronchiectasis in adults provide an evidence-based framework for the management of patients with bronchiectasis https://bit.ly/3VBk0eC
How testosterone fell out of favor in medicine — and how it came back www.statnews.com/2025/12/23/h... via @statnews.com
How testosterone fell out of favor in medicine — and how it came back
Abraham Morgentaler, a pioneer in testosterone therapy for men, discusses what led to decades of shunning of this hormone.
www.statnews.com
December 31, 2025 at 7:47 AM
How testosterone fell out of favor in medicine — and how it came back www.statnews.com/2025/12/23/h... via @statnews.com
Reposted by Euan Reid
98 million Americans have prediabetes. A recent landmark paper showed normalization of glucose in people with prediabetes is linked to halving of major cardiovascular adverse events over ensuing decades
thelancet.com/journals/lan...
thelancet.com/journals/lan...
Prediabetes remission and cardiovascular morbidity and mortality: post-hoc analyses from the Diabetes Prevention Program Outcome study and the DaQing Diabetes Prevention Outcome study
Reaching prediatbetes remission is linked to a decades-long benefit, halving the risk
of cardiovascular death or hospitalisation for heart failure in diverse populations.
Targeting remission might rep...
thelancet.com
December 28, 2025 at 5:09 PM
98 million Americans have prediabetes. A recent landmark paper showed normalization of glucose in people with prediabetes is linked to halving of major cardiovascular adverse events over ensuing decades
thelancet.com/journals/lan...
thelancet.com/journals/lan...
Reposted by Euan Reid
We are working with SIGN to develop a brand-new guideline focusing on specialist interventions for patients with severe asthma
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
December 23, 2025 at 2:03 PM
We are working with SIGN to develop a brand-new guideline focusing on specialist interventions for patients with severe asthma
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026