Government launches consultation to help combat rising drug deaths from opioids, as part of record £3.4 billion in investment in drug and alcohol services.
#Pharmsky
www.gov.uk/government/n...
#Pharmsky
www.gov.uk/government/n...
Lives to be saved by boosting access to drug overdose medication
Government launches consultation to help combat rising drug deaths from opioids, as part of record £3.4 billion in investment in drug and alcohol services.
www.gov.uk
December 31, 2025 at 9:37 AM
Government launches consultation to help combat rising drug deaths from opioids, as part of record £3.4 billion in investment in drug and alcohol services.
#Pharmsky
www.gov.uk/government/n...
#Pharmsky
www.gov.uk/government/n...
How medicines affect gut bacteria could inform safer, more effective use.
#Pharmsky
www.gov.uk/government/n...
#Pharmsky
www.gov.uk/government/n...
How medicines affect gut bacteria could inform safer, more effective use
Understanding gut microbiome interactions with medicines could help explain differences in how people respond to treatment and build on existing medicine safety knowledge to support safer, more effect...
www.gov.uk
December 31, 2025 at 8:01 AM
How medicines affect gut bacteria could inform safer, more effective use.
#Pharmsky
www.gov.uk/government/n...
#Pharmsky
www.gov.uk/government/n...
Reposted by Euan Reid
The @europeanrespsoc.bsky.social guidelines for the management of bronchiectasis in adults provide an evidence-based framework for the management of patients with bronchiectasis https://bit.ly/3VBk0eC
December 28, 2025 at 2:25 PM
The @europeanrespsoc.bsky.social guidelines for the management of bronchiectasis in adults provide an evidence-based framework for the management of patients with bronchiectasis https://bit.ly/3VBk0eC
How testosterone fell out of favor in medicine — and how it came back www.statnews.com/2025/12/23/h... via @statnews.com
How testosterone fell out of favor in medicine — and how it came back
Abraham Morgentaler, a pioneer in testosterone therapy for men, discusses what led to decades of shunning of this hormone.
www.statnews.com
December 31, 2025 at 7:47 AM
How testosterone fell out of favor in medicine — and how it came back www.statnews.com/2025/12/23/h... via @statnews.com
Reposted by Euan Reid
98 million Americans have prediabetes. A recent landmark paper showed normalization of glucose in people with prediabetes is linked to halving of major cardiovascular adverse events over ensuing decades
thelancet.com/journals/lan...
thelancet.com/journals/lan...
Prediabetes remission and cardiovascular morbidity and mortality: post-hoc analyses from the Diabetes Prevention Program Outcome study and the DaQing Diabetes Prevention Outcome study
Reaching prediatbetes remission is linked to a decades-long benefit, halving the risk
of cardiovascular death or hospitalisation for heart failure in diverse populations.
Targeting remission might rep...
thelancet.com
December 28, 2025 at 5:09 PM
98 million Americans have prediabetes. A recent landmark paper showed normalization of glucose in people with prediabetes is linked to halving of major cardiovascular adverse events over ensuing decades
thelancet.com/journals/lan...
thelancet.com/journals/lan...
Reposted by Euan Reid
We are working with SIGN to develop a brand-new guideline focusing on specialist interventions for patients with severe asthma
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
December 23, 2025 at 2:03 PM
We are working with SIGN to develop a brand-new guideline focusing on specialist interventions for patients with severe asthma
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
Reposted by Euan Reid
Longitudinal cohort study of over 30,000 participants from U.S. National Survey data finds a strong association between PPI users with reduced kidney function and death from any cause.
🚨 Caution is needed when considering PPI use for CKD patients!
Read the full article here:
buff.ly/kTz5275
🚨 Caution is needed when considering PPI use for CKD patients!
Read the full article here:
buff.ly/kTz5275
December 23, 2025 at 5:01 PM
Longitudinal cohort study of over 30,000 participants from U.S. National Survey data finds a strong association between PPI users with reduced kidney function and death from any cause.
🚨 Caution is needed when considering PPI use for CKD patients!
Read the full article here:
buff.ly/kTz5275
🚨 Caution is needed when considering PPI use for CKD patients!
Read the full article here:
buff.ly/kTz5275
December 23, 2025 at 10:51 AM
Position Statement on the use of Artificial Intelligence (AI) by
NHS professionals when answering medicine-related questions
#Pharmsky
www.ukmi.nhs.uk/fileDownload...
NHS professionals when answering medicine-related questions
#Pharmsky
www.ukmi.nhs.uk/fileDownload...
December 23, 2025 at 9:12 AM
Position Statement on the use of Artificial Intelligence (AI) by
NHS professionals when answering medicine-related questions
#Pharmsky
www.ukmi.nhs.uk/fileDownload...
NHS professionals when answering medicine-related questions
#Pharmsky
www.ukmi.nhs.uk/fileDownload...
Updated UK Medical Eligibility Criteria for Contraceptive Use (UKMEC) published
@cosrh.org #pharmsky
www.cosrh.org/Public/Publi...
@cosrh.org #pharmsky
www.cosrh.org/Public/Publi...
CoRSH publishes updated UKMEC 2025
The CoSRH Clinical Effectiveness Unit has issued an updated UK Medical Eligibility Criteria for Contraceptive Use (UKMEC) providing guidance on what contraception clinicians can safely recommend to th...
www.cosrh.org
December 23, 2025 at 8:23 AM
Updated UK Medical Eligibility Criteria for Contraceptive Use (UKMEC) published
@cosrh.org #pharmsky
www.cosrh.org/Public/Publi...
@cosrh.org #pharmsky
www.cosrh.org/Public/Publi...
Reposted by Euan Reid
We are working with SIGN to develop a brand-new guideline focusing on specialist interventions for patients with severe asthma
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
December 19, 2025 at 4:00 PM
We are working with SIGN to develop a brand-new guideline focusing on specialist interventions for patients with severe asthma
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
Read the draft scope and have your say 👉 brit-thoracic.uk/SIGNdraft25
Deadline: Wednesday 14th January 2026
Reposted by Euan Reid
As part of the PIP-STOPP study, read about an innovative approach to improve the applicability of the STOPP-START and Beers Criteria for identifying potentially inappropriate medications at a population-level using diagnostic & medication codes!
Find the open-access article here:
buff.ly/QZSFFfh
Find the open-access article here:
buff.ly/QZSFFfh
December 19, 2025 at 5:01 PM
As part of the PIP-STOPP study, read about an innovative approach to improve the applicability of the STOPP-START and Beers Criteria for identifying potentially inappropriate medications at a population-level using diagnostic & medication codes!
Find the open-access article here:
buff.ly/QZSFFfh
Find the open-access article here:
buff.ly/QZSFFfh
Reposted by Euan Reid
From January 2026, children will be offered a varicella (chickenpox) vaccine as part of the routine childhood schedule for the first time in Scotland.
Find out more 🔽
https://publichealthscotland.scot/news/2025/december/further-changes-to-childhood-vaccinations-in-scotland/
#ChildVaxScot
Find out more 🔽
https://publichealthscotland.scot/news/2025/december/further-changes-to-childhood-vaccinations-in-scotland/
#ChildVaxScot
December 19, 2025 at 10:56 AM
From January 2026, children will be offered a varicella (chickenpox) vaccine as part of the routine childhood schedule for the first time in Scotland.
Find out more 🔽
https://publichealthscotland.scot/news/2025/december/further-changes-to-childhood-vaccinations-in-scotland/
#ChildVaxScot
Find out more 🔽
https://publichealthscotland.scot/news/2025/december/further-changes-to-childhood-vaccinations-in-scotland/
#ChildVaxScot
Reposted by Euan Reid
"Higher intake of high-fat cheese and high-fat cream was associated with a lower risk of all-cause dementia."
Results of a 25-year prospective study of ~27,000 participants.
The purported benefit was not linked to APOE4 carriers or low-fat cheese intake
www.neurology.org/doi/full/10....
Results of a 25-year prospective study of ~27,000 participants.
The purported benefit was not linked to APOE4 carriers or low-fat cheese intake
www.neurology.org/doi/full/10....
December 17, 2025 at 10:05 PM
"Higher intake of high-fat cheese and high-fat cream was associated with a lower risk of all-cause dementia."
Results of a 25-year prospective study of ~27,000 participants.
The purported benefit was not linked to APOE4 carriers or low-fat cheese intake
www.neurology.org/doi/full/10....
Results of a 25-year prospective study of ~27,000 participants.
The purported benefit was not linked to APOE4 carriers or low-fat cheese intake
www.neurology.org/doi/full/10....
Carbohydrate Reduction and a Holistic Model of Care in Diabetes Management: Insights from a Retrospective Multi-Year Audit in New Zealand
Overall, 32.1% of patients with type 2 diabetes at baseline achieved reversal.
www.mdpi.com/2072-6643/17...
Overall, 32.1% of patients with type 2 diabetes at baseline achieved reversal.
www.mdpi.com/2072-6643/17...
December 17, 2025 at 10:49 PM
Carbohydrate Reduction and a Holistic Model of Care in Diabetes Management: Insights from a Retrospective Multi-Year Audit in New Zealand
Overall, 32.1% of patients with type 2 diabetes at baseline achieved reversal.
www.mdpi.com/2072-6643/17...
Overall, 32.1% of patients with type 2 diabetes at baseline achieved reversal.
www.mdpi.com/2072-6643/17...
New UK guideline for clopidogrel recommends pharmacogenetic testing for all patients before prescription
@liverpooluni.bsky.social
#Pharmsky
news.liverpool.ac.uk/2025/12/04/n...
@liverpooluni.bsky.social
#Pharmsky
news.liverpool.ac.uk/2025/12/04/n...
New UK guideline for clopidogrel recommends pharmacogenetic testing for all patients before prescription - University of Liverpool News
New UK guideline for clopidogrel recommends pharmacogenetic testing for all patients before prescription
news.liverpool.ac.uk
December 17, 2025 at 10:16 PM
New UK guideline for clopidogrel recommends pharmacogenetic testing for all patients before prescription
@liverpooluni.bsky.social
#Pharmsky
news.liverpool.ac.uk/2025/12/04/n...
@liverpooluni.bsky.social
#Pharmsky
news.liverpool.ac.uk/2025/12/04/n...
This @asthmaandlung.org.uk report marks one year since the publication of the updated asthma guideline. It outlines changes in how asthma is diagnosed and managed, highlights early improvements in care, and identifies where challenges remain.
#pharmsky
www.asthmaandlung.org.uk/ng245-one-year
#pharmsky
www.asthmaandlung.org.uk/ng245-one-year
NG245 One Year On
Our new report marks one year since the publication of the updated asthma guideline (NG245) and assesses initial progress across the UK. It outlines changes in how asthma is diagnosed and managed, hig...
www.asthmaandlung.org.uk
December 17, 2025 at 10:05 PM
This @asthmaandlung.org.uk report marks one year since the publication of the updated asthma guideline. It outlines changes in how asthma is diagnosed and managed, highlights early improvements in care, and identifies where challenges remain.
#pharmsky
www.asthmaandlung.org.uk/ng245-one-year
#pharmsky
www.asthmaandlung.org.uk/ng245-one-year
SIGN 173: management of chronic pain
This interim guideline replaces SIGN 136: Management of chronic pain. It contains the first part of the content of this guideline. The second part will be added in summer 2026.
#Pharmsky
www.sign.ac.uk/guidelines/m...
This interim guideline replaces SIGN 136: Management of chronic pain. It contains the first part of the content of this guideline. The second part will be added in summer 2026.
#Pharmsky
www.sign.ac.uk/guidelines/m...
Management of chronic pain
This guideline focuses on managing chronic non-malignant pain (pain lasting longer than 12 weeks) in adults. It applies to non-specialist healthcare settings that are not specifically designed for tre...
www.sign.ac.uk
December 17, 2025 at 9:58 PM
SIGN 173: management of chronic pain
This interim guideline replaces SIGN 136: Management of chronic pain. It contains the first part of the content of this guideline. The second part will be added in summer 2026.
#Pharmsky
www.sign.ac.uk/guidelines/m...
This interim guideline replaces SIGN 136: Management of chronic pain. It contains the first part of the content of this guideline. The second part will be added in summer 2026.
#Pharmsky
www.sign.ac.uk/guidelines/m...
Reposted by Euan Reid
#JAMAROTY25: Semaglutide and Tirzepatide in Patients with HFpEF
#Semaglutide and #Tirzepatide were both associated with a more than 40% lower risk of heart failure hospitalization or all-cause death in patients with cardiometabolic #HFpEF compared with a placebo proxy.
🔗 ja.ma/48BSc1a
#Semaglutide and #Tirzepatide were both associated with a more than 40% lower risk of heart failure hospitalization or all-cause death in patients with cardiometabolic #HFpEF compared with a placebo proxy.
🔗 ja.ma/48BSc1a
December 12, 2025 at 4:15 PM
#JAMAROTY25: Semaglutide and Tirzepatide in Patients with HFpEF
#Semaglutide and #Tirzepatide were both associated with a more than 40% lower risk of heart failure hospitalization or all-cause death in patients with cardiometabolic #HFpEF compared with a placebo proxy.
🔗 ja.ma/48BSc1a
#Semaglutide and #Tirzepatide were both associated with a more than 40% lower risk of heart failure hospitalization or all-cause death in patients with cardiometabolic #HFpEF compared with a placebo proxy.
🔗 ja.ma/48BSc1a
Rybelsus ® (semaglutide tablets): transition to new formulation and risk of medication error
#Pharmsky
@mhragovuk.bsky.social
www.gov.uk/drug-safety-...
#Pharmsky
@mhragovuk.bsky.social
www.gov.uk/drug-safety-...
Rybelsus ® (semaglutide tablets): transition to new formulation and risk of medication error
There is a risk of patient harm arising through medication error during a transition period where the original and new formulation of Rybelsus ® tablets, which have different stated mg doses but are b...
www.gov.uk
December 17, 2025 at 4:08 PM
Rybelsus ® (semaglutide tablets): transition to new formulation and risk of medication error
#Pharmsky
@mhragovuk.bsky.social
www.gov.uk/drug-safety-...
#Pharmsky
@mhragovuk.bsky.social
www.gov.uk/drug-safety-...
The MHRA has approved depemokimab (Exdensur), the first twice-yearly biological medicine for use as an add-on treatment for asthma in adults and adolescents aged 12 years and older, and as an add-on treatment for severe chronic rhinosinusitis with nasal polyps in adults.
www.gov.uk/government/n...
www.gov.uk/government/n...
UK approves the first twice yearly biological medicine for asthma and severe chronic rhinosinusitis with nasal polyps
As with any medicine, the MHRA will keep the safety and effectiveness of depemokimab under close review.
www.gov.uk
December 17, 2025 at 4:02 PM
The MHRA has approved depemokimab (Exdensur), the first twice-yearly biological medicine for use as an add-on treatment for asthma in adults and adolescents aged 12 years and older, and as an add-on treatment for severe chronic rhinosinusitis with nasal polyps in adults.
www.gov.uk/government/n...
www.gov.uk/government/n...
The MHRA has approved the reclassification of fluticasone propionate (Pirinase Allergy 0.05% w/w Nasal Spray), making it available directly from behind pharmacy counters, without the need for a prescription, for adolescents aged 12 years and over.
#Pharmsky
www.gov.uk/government/n...
#Pharmsky
www.gov.uk/government/n...
European first as MHRA approves over-the-counter allergy treatment for adolescents aged 12 and over
As with any medicine, the MHRA will keep the safety and effectiveness of fluticasone propionate under close review.
www.gov.uk
December 17, 2025 at 9:04 AM
The MHRA has approved the reclassification of fluticasone propionate (Pirinase Allergy 0.05% w/w Nasal Spray), making it available directly from behind pharmacy counters, without the need for a prescription, for adolescents aged 12 years and over.
#Pharmsky
www.gov.uk/government/n...
#Pharmsky
www.gov.uk/government/n...
Reposted by Euan Reid
"One small molecule for man, one giant leap for mankind with obesity"
sciencedirect.com/science/arti...
But the very high amounts of drug in pills relative to injectable peptides, due to such poor bioavailability, means we need to be watchful for new side effects when these pills get widely used
sciencedirect.com/science/arti...
But the very high amounts of drug in pills relative to injectable peptides, due to such poor bioavailability, means we need to be watchful for new side effects when these pills get widely used
One small molecule for man, one giant leap for mankind with obesity
The ATTAIN-1 trial launches a new era in obesity care. Orforglipron, the first oral small-molecule GLP-1 receptor agonist to complete a phase 3 clinic…
sciencedirect.com
December 12, 2025 at 9:30 PM
"One small molecule for man, one giant leap for mankind with obesity"
sciencedirect.com/science/arti...
But the very high amounts of drug in pills relative to injectable peptides, due to such poor bioavailability, means we need to be watchful for new side effects when these pills get widely used
sciencedirect.com/science/arti...
But the very high amounts of drug in pills relative to injectable peptides, due to such poor bioavailability, means we need to be watchful for new side effects when these pills get widely used
Reposted by Euan Reid
Normalization of glucose in people with prediabetes, i.e. achieving remission, is linked to halving of major cardiovascular adverse events over ensuing decades
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Prediabetes remission and cardiovascular morbidity and mortality: post-hoc analyses from the Diabetes Prevention Program Outcome study and the DaQing Diabetes Prevention Outcome study
Reaching prediatbetes remission is linked to a decades-long benefit, halving the risk
of cardiovascular death or hospitalisation for heart failure in diverse populations.
Targeting remission might rep...
www.thelancet.com
December 13, 2025 at 12:43 AM
Normalization of glucose in people with prediabetes, i.e. achieving remission, is linked to halving of major cardiovascular adverse events over ensuing decades
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Reposted by Euan Reid
GPs don't provide enough support for people diagnosed with frailty.
Just 1 in 6 patients aged 65+ were assessed for frailty in 2024-25. We recommend @england.nhs.uk sets out clear & consistent requirements to assess & support people living with frailty.
➡️ www.nao.org.uk/reports/prim...
Just 1 in 6 patients aged 65+ were assessed for frailty in 2024-25. We recommend @england.nhs.uk sets out clear & consistent requirements to assess & support people living with frailty.
➡️ www.nao.org.uk/reports/prim...
December 5, 2025 at 7:00 AM
GPs don't provide enough support for people diagnosed with frailty.
Just 1 in 6 patients aged 65+ were assessed for frailty in 2024-25. We recommend @england.nhs.uk sets out clear & consistent requirements to assess & support people living with frailty.
➡️ www.nao.org.uk/reports/prim...
Just 1 in 6 patients aged 65+ were assessed for frailty in 2024-25. We recommend @england.nhs.uk sets out clear & consistent requirements to assess & support people living with frailty.
➡️ www.nao.org.uk/reports/prim...