Emily Blythe
@emilyblythe.bsky.social
Assistant Professor at the University of Minnesota Twin Cities | Biochemist & cell biologist / GPCRs | UCSF Postdoc, Caltech PhD | she/her
blythelab.umn.edu
blythelab.umn.edu
Reposted by Emily Blythe
ATTN: Two faculty positions are available in my department (neuroscience) at the University of Minnesota. This is a general search with no topic focus. November 20th application deadline.
Apply here: hr.umn.edu/jobs/Find-Job
Assistant Prof job code: 364920
Associate/Full Prof job code: 364921
Apply here: hr.umn.edu/jobs/Find-Job
Assistant Prof job code: 364920
Associate/Full Prof job code: 364921
October 30, 2025 at 3:59 PM
ATTN: Two faculty positions are available in my department (neuroscience) at the University of Minnesota. This is a general search with no topic focus. November 20th application deadline.
Apply here: hr.umn.edu/jobs/Find-Job
Assistant Prof job code: 364920
Associate/Full Prof job code: 364921
Apply here: hr.umn.edu/jobs/Find-Job
Assistant Prof job code: 364920
Associate/Full Prof job code: 364921
Reposted by Emily Blythe
Now online @nature.com!
Want to change the consequences of receptor activation?
Small molecules binding the GPCR-transducer interface change G protein subtype preference in predictable ways, enabling rational drug design 💥
So many new possibilities! 🧪🧠🟦
www.nature.com/articles/s41...
🧵👇
Want to change the consequences of receptor activation?
Small molecules binding the GPCR-transducer interface change G protein subtype preference in predictable ways, enabling rational drug design 💥
So many new possibilities! 🧪🧠🟦
www.nature.com/articles/s41...
🧵👇
Designing allosteric modulators to change GPCR G protein subtype selectivity - Nature
Studies of the G-protein-coupled receptor NTSR1 show that the G protein selectivity of this receptor can be modified by small molecules, enabling the design of drugs that work by switching receptor su...
www.nature.com
October 27, 2025 at 8:50 PM
Now online @nature.com!
Want to change the consequences of receptor activation?
Small molecules binding the GPCR-transducer interface change G protein subtype preference in predictable ways, enabling rational drug design 💥
So many new possibilities! 🧪🧠🟦
www.nature.com/articles/s41...
🧵👇
Want to change the consequences of receptor activation?
Small molecules binding the GPCR-transducer interface change G protein subtype preference in predictable ways, enabling rational drug design 💥
So many new possibilities! 🧪🧠🟦
www.nature.com/articles/s41...
🧵👇
Reposted by Emily Blythe
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Scaling back DEI programmes and the loss of scientific talent
Nature Cell Biology - Programmes that support diversity, equity and inclusion (DEI) in science are under attack in the USA. Data indicate that diversity in the scientific workforce increases...
www.nature.com
October 23, 2025 at 4:36 PM
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Reposted by Emily Blythe
🚀 Hey #GPCR community on #bluesky!
🌍 The 2nd GPCR Forum Virtual Conference is taking place!🧬
📅 Nov 12–14, 2025
This 3-day virtual event will bring together scientists and researchers from around the world to explore the latest breakthroughs in GPCR!
#GPCRforum #ScienceTogether
🌍 The 2nd GPCR Forum Virtual Conference is taking place!🧬
📅 Nov 12–14, 2025
This 3-day virtual event will bring together scientists and researchers from around the world to explore the latest breakthroughs in GPCR!
#GPCRforum #ScienceTogether
October 6, 2025 at 12:45 PM
🚀 Hey #GPCR community on #bluesky!
🌍 The 2nd GPCR Forum Virtual Conference is taking place!🧬
📅 Nov 12–14, 2025
This 3-day virtual event will bring together scientists and researchers from around the world to explore the latest breakthroughs in GPCR!
#GPCRforum #ScienceTogether
🌍 The 2nd GPCR Forum Virtual Conference is taking place!🧬
📅 Nov 12–14, 2025
This 3-day virtual event will bring together scientists and researchers from around the world to explore the latest breakthroughs in GPCR!
#GPCRforum #ScienceTogether
Reposted by Emily Blythe
A new special issue entitled “Emerging Voices in GPCR Biology” is now available in Molecular Pharmacology, highlighting innovative research led by early-career investigators (ECIs) across key areas of G protein-coupled receptor (GPCR) science.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Emerging Voices in GPCR Biology
www.sciencedirect.com
October 13, 2025 at 10:24 AM
A new special issue entitled “Emerging Voices in GPCR Biology” is now available in Molecular Pharmacology, highlighting innovative research led by early-career investigators (ECIs) across key areas of G protein-coupled receptor (GPCR) science.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Emily Blythe
My lab @stanfordmedicine.bsky.social is recruiting! We are looking for a postdoc at the interface of quantitative proteomics and G protein-coupled receptor (GPCR) biology:
postdocs.stanford.edu/prospective/...
#TeamMassSpec #Proteomics #GPCR #Postdoc
postdocs.stanford.edu/prospective/...
#TeamMassSpec #Proteomics #GPCR #Postdoc
Open Postdoctoral position, faculty mentor Ruth Huttenhain | Office of Postdoctoral Affairs
postdocs.stanford.edu
October 2, 2025 at 6:27 PM
My lab @stanfordmedicine.bsky.social is recruiting! We are looking for a postdoc at the interface of quantitative proteomics and G protein-coupled receptor (GPCR) biology:
postdocs.stanford.edu/prospective/...
#TeamMassSpec #Proteomics #GPCR #Postdoc
postdocs.stanford.edu/prospective/...
#TeamMassSpec #Proteomics #GPCR #Postdoc
Reposted by Emily Blythe
"Talent and grit matter, but so do structure, transparency, and care." #ScienceWorkingLife https://scim.ag/4nCiPYg
September 23, 2025 at 5:03 PM
"Talent and grit matter, but so do structure, transparency, and care." #ScienceWorkingLife https://scim.ag/4nCiPYg
Reposted by Emily Blythe
Applying to the NSF-GRFP (or another fellowship) on a tight deadline?
We built a 7-week guide + timeline to get you from draft to submission. It’s not too late — you’ve got this! ✨
🔗 cientificolatino.com/apply-in-7-weeks
#NSFGRFP #GradSchool #Fellowship
We built a 7-week guide + timeline to get you from draft to submission. It’s not too late — you’ve got this! ✨
🔗 cientificolatino.com/apply-in-7-weeks
#NSFGRFP #GradSchool #Fellowship
September 9, 2025 at 4:14 PM
Applying to the NSF-GRFP (or another fellowship) on a tight deadline?
We built a 7-week guide + timeline to get you from draft to submission. It’s not too late — you’ve got this! ✨
🔗 cientificolatino.com/apply-in-7-weeks
#NSFGRFP #GradSchool #Fellowship
We built a 7-week guide + timeline to get you from draft to submission. It’s not too late — you’ve got this! ✨
🔗 cientificolatino.com/apply-in-7-weeks
#NSFGRFP #GradSchool #Fellowship
Reposted by Emily Blythe
New NYT article detailing new requirements for the COVID-19 vaccine across US. This is all very preliminary information, but I suggest if you live in these states that may require a prescription, you acquire a script from your family doctor asap.
August 29, 2025 at 6:22 PM
New NYT article detailing new requirements for the COVID-19 vaccine across US. This is all very preliminary information, but I suggest if you live in these states that may require a prescription, you acquire a script from your family doctor asap.
Reposted by Emily Blythe
Our preprint “GPCR endocytosis rewires neuronal gene expression and cellular architecture” is now live on bioRxiv.
🔗 doi.org/10.1101/2025...
We uncover how GPCR trafficking shapes protein content and neuronal structure. Congratulations to our team members, Katherine Hall and Matt Klauer!
A short🧵
🔗 doi.org/10.1101/2025...
We uncover how GPCR trafficking shapes protein content and neuronal structure. Congratulations to our team members, Katherine Hall and Matt Klauer!
A short🧵
August 28, 2025 at 2:09 PM
Our preprint “GPCR endocytosis rewires neuronal gene expression and cellular architecture” is now live on bioRxiv.
🔗 doi.org/10.1101/2025...
We uncover how GPCR trafficking shapes protein content and neuronal structure. Congratulations to our team members, Katherine Hall and Matt Klauer!
A short🧵
🔗 doi.org/10.1101/2025...
We uncover how GPCR trafficking shapes protein content and neuronal structure. Congratulations to our team members, Katherine Hall and Matt Klauer!
A short🧵
The Blythe Lab is growing! This summer we welcomed our first lab members: junior researcher Eamon Cole and postdoc Dr. Chantel Mastos.
August 21, 2025 at 8:51 PM
The Blythe Lab is growing! This summer we welcomed our first lab members: junior researcher Eamon Cole and postdoc Dr. Chantel Mastos.
Reposted by Emily Blythe
A new paper proposes an ‘intracrine’ signaling mechanism whereby a G protein-coupled receptor (FFA4) senses locally released fatty acids on intracellular membranes associated with lipid droplets to efficiently regulate lipolysis in adipocytes
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Intracrine FFA4 signaling controls lipolysis at lipid droplets - Nature Chemical Biology
An ‘intracrine’ signaling mechanism is proposed whereby a G-protein-coupled receptor (free fatty acid receptor 4) senses locally released fatty acids on intracellular membranes associated with lipid d...
www.nature.com
August 7, 2025 at 2:54 PM
A new paper proposes an ‘intracrine’ signaling mechanism whereby a G protein-coupled receptor (FFA4) senses locally released fatty acids on intracellular membranes associated with lipid droplets to efficiently regulate lipolysis in adipocytes
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Emily Blythe
🚨 New preprint alert! 🚨
Excited to share my latest work, now on bioRxiv:
“Altered striatal dopamine regulation in ADGRL3 knockout mice”
🔗 www.biorxiv.org/content/10.1...
Excited to share my latest work, now on bioRxiv:
“Altered striatal dopamine regulation in ADGRL3 knockout mice”
🔗 www.biorxiv.org/content/10.1...
Altered striatal dopamine regulation in ADGRL3 knockout mice
Dopaminergic signaling is essential for regulating movement, learning, and reward. Disruptions in this system are linked to neuropsychiatric disorders such as ADHD. ADGRL3, an adhesion G protein-coupl...
www.biorxiv.org
August 1, 2025 at 1:20 PM
🚨 New preprint alert! 🚨
Excited to share my latest work, now on bioRxiv:
“Altered striatal dopamine regulation in ADGRL3 knockout mice”
🔗 www.biorxiv.org/content/10.1...
Excited to share my latest work, now on bioRxiv:
“Altered striatal dopamine regulation in ADGRL3 knockout mice”
🔗 www.biorxiv.org/content/10.1...
Reposted by Emily Blythe
“If you cut out these diversity measures, you're going to make science full of people that are very elite…Full of people who have grown up with a large amount of privilege, who were able to work in a lab in high school because their dad was a prof at Cornell.” 🧪
www.nytimes.com/2025/07/10/u...
www.nytimes.com/2025/07/10/u...
How Trump’s D.E.I. Cuts Are Hurting Rural White Americans Too
www.nytimes.com
July 10, 2025 at 12:37 PM
“If you cut out these diversity measures, you're going to make science full of people that are very elite…Full of people who have grown up with a large amount of privilege, who were able to work in a lab in high school because their dad was a prof at Cornell.” 🧪
www.nytimes.com/2025/07/10/u...
www.nytimes.com/2025/07/10/u...
Reposted by Emily Blythe
BOOM! Last nite we blew through the 20K mark and already @ 21K and counting.
Wanna feel what it feels like to stand together w/ 20,000+ other science stans supporting the heroes of the #BethesdaDeclaration?
CLICK to sign our #NIHLoveLetter here actionnetwork.org/forms/add-na...
#StandUpForScience
Wanna feel what it feels like to stand together w/ 20,000+ other science stans supporting the heroes of the #BethesdaDeclaration?
CLICK to sign our #NIHLoveLetter here actionnetwork.org/forms/add-na...
#StandUpForScience
June 12, 2025 at 10:21 AM
BOOM! Last nite we blew through the 20K mark and already @ 21K and counting.
Wanna feel what it feels like to stand together w/ 20,000+ other science stans supporting the heroes of the #BethesdaDeclaration?
CLICK to sign our #NIHLoveLetter here actionnetwork.org/forms/add-na...
#StandUpForScience
Wanna feel what it feels like to stand together w/ 20,000+ other science stans supporting the heroes of the #BethesdaDeclaration?
CLICK to sign our #NIHLoveLetter here actionnetwork.org/forms/add-na...
#StandUpForScience
Reposted by Emily Blythe
If you weren't angry enough already, here are the rates of non-competitive renewals through May.
4008 Non-competitive renewals were due to be funded in May.
The total funded was 99!
Some is due to terminations, but most is due to slow grant making due to DOGE review and other impediments.
1/2
4008 Non-competitive renewals were due to be funded in May.
The total funded was 99!
Some is due to terminations, but most is due to slow grant making due to DOGE review and other impediments.
1/2
June 9, 2025 at 1:22 PM
If you weren't angry enough already, here are the rates of non-competitive renewals through May.
4008 Non-competitive renewals were due to be funded in May.
The total funded was 99!
Some is due to terminations, but most is due to slow grant making due to DOGE review and other impediments.
1/2
4008 Non-competitive renewals were due to be funded in May.
The total funded was 99!
Some is due to terminations, but most is due to slow grant making due to DOGE review and other impediments.
1/2
Reposted by Emily Blythe
The Trump administration is unlawfully seeking to destroy higher education in the United States. It now demands that we sacrifice our international students in the process. Universities cannot acquiesce to such extortion.
New on Academe Blog: academeblog.org/2025/05/23/a...
AAUP-Harvard Faculty Chapter Executive Committee Condemns Trump Administration’s Termination of Harvard’s SEVP Certification
POSTED BY HANK REICHMAN The following statement was issued yesterday in response to a decision earlier that day by the Department of Homeland Security to revoke Harvard University’s certifica…
academeblog.org
May 27, 2025 at 6:47 PM
The Trump administration is unlawfully seeking to destroy higher education in the United States. It now demands that we sacrifice our international students in the process. Universities cannot acquiesce to such extortion.
Reposted by Emily Blythe
Three new papers in Science report that astrocytes are indispensable for neuromodulatory signaling across diverse neural circuits, behavioral contexts, and species.
Learn more in a new #SciencePerspective: scim.ag/43iprSX
Learn more in a new #SciencePerspective: scim.ag/43iprSX
Astrocytes, hidden puppet masters of the brain
Astrocyte signaling pathways influence neuronal networks and behavioral responses to neuromodulators
scim.ag
May 16, 2025 at 3:10 PM
Three new papers in Science report that astrocytes are indispensable for neuromodulatory signaling across diverse neural circuits, behavioral contexts, and species.
Learn more in a new #SciencePerspective: scim.ag/43iprSX
Learn more in a new #SciencePerspective: scim.ag/43iprSX
Reposted by Emily Blythe
The NIH has dropped its research funding by $2.7 billion so far this year.
Cancer research funding has declined 31%.
And new NIH research grants fell to the lowest level in more than a decade.
Eye-opening findings in today's HELP committee minority report:
www.sanders.senate.gov/wp-content/u...
Cancer research funding has declined 31%.
And new NIH research grants fell to the lowest level in more than a decade.
Eye-opening findings in today's HELP committee minority report:
www.sanders.senate.gov/wp-content/u...
May 13, 2025 at 3:22 PM
The NIH has dropped its research funding by $2.7 billion so far this year.
Cancer research funding has declined 31%.
And new NIH research grants fell to the lowest level in more than a decade.
Eye-opening findings in today's HELP committee minority report:
www.sanders.senate.gov/wp-content/u...
Cancer research funding has declined 31%.
And new NIH research grants fell to the lowest level in more than a decade.
Eye-opening findings in today's HELP committee minority report:
www.sanders.senate.gov/wp-content/u...
Reposted by Emily Blythe
New report from Bernie Sanders, ranking member on the HELP committee
www.sanders.senate.gov/wp-content/u...
Lots of substance in here. Some highlights...
1/n
www.sanders.senate.gov/wp-content/u...
Lots of substance in here. Some highlights...
1/n
www.sanders.senate.gov
May 13, 2025 at 3:07 PM
New report from Bernie Sanders, ranking member on the HELP committee
www.sanders.senate.gov/wp-content/u...
Lots of substance in here. Some highlights...
1/n
www.sanders.senate.gov/wp-content/u...
Lots of substance in here. Some highlights...
1/n
Reposted by Emily Blythe
Unlawful grant terminations are harming young scientists and threatening innovation. ASCB joins leaders calling for immediate funding restoration.
www.ascb.org/society-news...
www.ascb.org/society-news...
Leading Life Science Organizations: Unlawful Grant Terminations Pose Grave Threat to America’s Innovation Pipeline - ASCB
Amicus Brief Filed in Support of Suit Calling for Immediate Funding Restoration WASHINGTON, DC – Four leading life science organizations, including the ASCB, filed an amicus brief today asking the cou...
www.ascb.org
May 2, 2025 at 7:03 PM
Unlawful grant terminations are harming young scientists and threatening innovation. ASCB joins leaders calling for immediate funding restoration.
www.ascb.org/society-news...
www.ascb.org/society-news...
Reposted by Emily Blythe
Reposted by Emily Blythe
Excited to share my first paper from my postdoc! In this study, we demonstrate that the mu opioid receptor produces a second wave of G protein activity on endosomes in a manner that doesn’t require receptor internalization. Check it out! www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
April 25, 2025 at 4:09 PM
Excited to share my first paper from my postdoc! In this study, we demonstrate that the mu opioid receptor produces a second wave of G protein activity on endosomes in a manner that doesn’t require receptor internalization. Check it out! www.pnas.org/doi/10.1073/...
Reposted by Emily Blythe
Happy to have this out there! I had a lot of fun working with (and learning from) @akshitg.bsky.social on this mini-review on microdiversity in microbial populations and how current ecological theory fails to quantitatively explain the observations. doi.org/10.1111/1462...
Paradox of the Sub‐Plankton: Plausible Mechanisms and Open Problems Underlying Strain‐Level Diversity in Microbial Communities
“Paradox of the sub-plankton: Plausible mechanisms and open problems underlying strain-level diversity in microbial communities” by Akshit Goyal* and Griffin Chure*. This work highlights the limitati...
doi.org
April 25, 2025 at 6:10 PM
Happy to have this out there! I had a lot of fun working with (and learning from) @akshitg.bsky.social on this mini-review on microdiversity in microbial populations and how current ecological theory fails to quantitatively explain the observations. doi.org/10.1111/1462...
Reposted by Emily Blythe
Ever wonder how many lives have been saved by NIH-funded research - including your own? Enter any medical condition and instantly see how your tax dollars transformed science into survival.
www.ourhealthroi.com
www.ourhealthroi.com
Our Health ROI
Explore how your tax dollars fund life‑saving medical research.
www.ourhealthroi.com
April 21, 2025 at 3:51 AM
Ever wonder how many lives have been saved by NIH-funded research - including your own? Enter any medical condition and instantly see how your tax dollars transformed science into survival.
www.ourhealthroi.com
www.ourhealthroi.com