Emilia Kuuluvainen
@emiliakuul.bsky.social
PhD at University of Helsinki, Finland studying Metabolism, Mitochondrial age, Stem Cells and Transcription at Katajistolab and MetaStem. Coordinator of Research and Family life
Reposted by Emilia Kuuluvainen
Welcome to the PhD defense of @hienbui.bsky.social Age-selective segregation of organelles in asymmetric stem cell division, on Fri 7 Nov at 1 pm, Biocenter 2, 2041. Opponent Prof Carien Niessen, University of Cologne @helsinki.fi @hilife-helsinki.bsky.social #publicdefense #phddefense
November 5, 2025 at 7:59 AM
Welcome to the PhD defense of @hienbui.bsky.social Age-selective segregation of organelles in asymmetric stem cell division, on Fri 7 Nov at 1 pm, Biocenter 2, 2041. Opponent Prof Carien Niessen, University of Cologne @helsinki.fi @hilife-helsinki.bsky.social #publicdefense #phddefense
Reposted by Emilia Kuuluvainen
Still time today to sign up and submit an abstract for this excellent symposium
Excited to announce our Stem Cell Metabolism Symposium organized in Helsinki on November 12th. Fantastic invited speakers Marcia Haigis, Lydia Finley, Matthias Hebrok and Tom MacVicar. Sign up by Oct 22nd, free of charge, welcome! @hilife-helsinki.bsky.social @helsinki.fi @stemmprogram.bsky.social
October 22, 2025 at 10:32 AM
Still time today to sign up and submit an abstract for this excellent symposium
Reposted by Emilia Kuuluvainen
On Tue Oct 14th @simonsterson.bsky.social will defend his thesis Age-selective organellar metabolism in tissue stem cell function, at 1 pm in Biocenter 2 2041, Viikki. Excited to have Jared Rutter @rutterlab.bsky.social as the opponent 🎩⚔️ Welcome! @metastem.bsky.social @hilife-helsinki.bsky.social
October 9, 2025 at 12:11 PM
On Tue Oct 14th @simonsterson.bsky.social will defend his thesis Age-selective organellar metabolism in tissue stem cell function, at 1 pm in Biocenter 2 2041, Viikki. Excited to have Jared Rutter @rutterlab.bsky.social as the opponent 🎩⚔️ Welcome! @metastem.bsky.social @hilife-helsinki.bsky.social
Reposted by Emilia Kuuluvainen
Excited to announce our Stem Cell Metabolism Symposium organized in Helsinki on November 12th. Fantastic invited speakers Marcia Haigis, Lydia Finley, Matthias Hebrok and Tom MacVicar. Sign up by Oct 22nd, free of charge, welcome! @hilife-helsinki.bsky.social @helsinki.fi @stemmprogram.bsky.social
October 1, 2025 at 10:33 AM
Excited to announce our Stem Cell Metabolism Symposium organized in Helsinki on November 12th. Fantastic invited speakers Marcia Haigis, Lydia Finley, Matthias Hebrok and Tom MacVicar. Sign up by Oct 22nd, free of charge, welcome! @hilife-helsinki.bsky.social @helsinki.fi @stemmprogram.bsky.social
Reposted by Emilia Kuuluvainen
Welcome to the Stem Cell Seminar next week Friday Oct 3rd at 9-11, ☕️🍪 at 8:30. Exciting science on embryo development, ECM, cancer and stem cells by Juha Kere and @johannaienglund.bsky.social labs. See you there! @hilife-helsinki.bsky.social @helsinki-biotech.bsky.social @stemmprogram.bsky.social
September 24, 2025 at 6:21 AM
Welcome to the Stem Cell Seminar next week Friday Oct 3rd at 9-11, ☕️🍪 at 8:30. Exciting science on embryo development, ECM, cancer and stem cells by Juha Kere and @johannaienglund.bsky.social labs. See you there! @hilife-helsinki.bsky.social @helsinki-biotech.bsky.social @stemmprogram.bsky.social
Reposted by Emilia Kuuluvainen
News from our CoE by @otonkoskit.bsky.social lab, Eliisa Vähäkangas et al show that upon engraftment into mice stem cell derived pancreatic islets become insensitive to pyruvate, correlating with down regulation of the pyruvate/lactate transporter MCT1. link.springer.com/article/10.1... @helsinki.fi
Stem-cell-derived beta cells mature metabolically upon murine engraftment - Diabetologia
Aims/hypothesis The use of stem-cell-derived islets (SC-islets) as a source for cell-based therapy of type 1 diabetes shows great potential. However, SC-islets have a metabolically immature phenotype ...
link.springer.com
July 28, 2025 at 7:46 AM
News from our CoE by @otonkoskit.bsky.social lab, Eliisa Vähäkangas et al show that upon engraftment into mice stem cell derived pancreatic islets become insensitive to pyruvate, correlating with down regulation of the pyruvate/lactate transporter MCT1. link.springer.com/article/10.1... @helsinki.fi
Reposted by Emilia Kuuluvainen
News from our CoE by @katajistolab.bsky.social @simonsterson.bsky.social found that intestinal stem cells with old mitochondria make Paneth cells faster due to higher aKG levels and aKG improves regeneration in old animals by renewal of Paneth cells. www.nature.com/articles/s42... @helsinki.fi
Old mitochondria regulate niche renewal via α-ketoglutarate metabolism in stem cells - Nature Metabolism
Andersson et al. show that intestinal stem cells enriched for old mitochondria are metabolically distinct and have enhanced ability to regenerate the epithelial niche.
www.nature.com
July 28, 2025 at 8:01 AM
News from our CoE by @katajistolab.bsky.social @simonsterson.bsky.social found that intestinal stem cells with old mitochondria make Paneth cells faster due to higher aKG levels and aKG improves regeneration in old animals by renewal of Paneth cells. www.nature.com/articles/s42... @helsinki.fi
Reposted by Emilia Kuuluvainen
Proudly presenting Simon’s @simonsterson.bsky.social paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism
@naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
@naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
Old mitochondria regulate niche renewal via α-ketoglutarate metabolism in stem cells - Nature Metabolism
Andersson et al. show that intestinal stem cells enriched for old mitochondria are metabolically distinct and have enhanced ability to regenerate the epithelial niche.
www.nature.com
July 14, 2025 at 10:21 AM
Proudly presenting Simon’s @simonsterson.bsky.social paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism
@naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
@naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
Reposted by Emilia Kuuluvainen
News from our CoE by @htyynismaa.bsky.social group characterize the role of mitochondrial intermembrane space protein CHCHD10 in metabolism and spinal muscular atrophy Jokela type (SMAJ) actaneurocomms.biomedcentral.com/articles/10.... Congratulations Sandra! @helsinki.fi @stemmprogram.bsky.social
Dose-dependent CHCHD10 dysregulation dictates motor neuron disease severity and alters creatine metabolism - Acta Neuropathologica Communications
Dominant defects in CHCHD10, a mitochondrial intermembrane space protein, lead to a range of neurological and muscle disease phenotypes including amyotrophic lateral sclerosis. Many patients present w...
actaneurocomms.biomedcentral.com
May 22, 2025 at 6:00 AM
News from our CoE by @htyynismaa.bsky.social group characterize the role of mitochondrial intermembrane space protein CHCHD10 in metabolism and spinal muscular atrophy Jokela type (SMAJ) actaneurocomms.biomedcentral.com/articles/10.... Congratulations Sandra! @helsinki.fi @stemmprogram.bsky.social
Reposted by Emilia Kuuluvainen
Thank you to the organizers of the fantastic meeting #CSMetabolites2025 Kivanc Birsoy @robzonculab.bsky.social and @cellpress.bsky.social editors Allyson Evans @kristabledsoe.bsky.social We had a fantastic time in Sitges, looking forward to this meeting happening again! @cellpressevents.bsky.social
May 15, 2025 at 8:26 AM
Thank you to the organizers of the fantastic meeting #CSMetabolites2025 Kivanc Birsoy @robzonculab.bsky.social and @cellpress.bsky.social editors Allyson Evans @kristabledsoe.bsky.social We had a fantastic time in Sitges, looking forward to this meeting happening again! @cellpressevents.bsky.social
Read Hien’s fantastic paper on the age-selective apportioning of peroxisomes affecting stem cell fate through metabolism, congratulations Hien 🥳
Happy to present Hien’s paper on age-selective apportioning of peroxisomes as a fate determinant in adult stem cells www.nature.com/articles/s41... @metastem.bsky.social @helsinki.fi @ki.se @helsinki-biotech.bsky.social out now in @natcomms.nature.com
A thread 🧵 1/9
A thread 🧵 1/9
Glucose-6-phosphate-dehydrogenase on old peroxisomes maintains self-renewal of epithelial stem cells after asymmetric cell division - Nature Communications
Peroxisomes are essential but their role in cell fate regulation remains understudied. Here, the authors reveal that young and old peroxisomes are not equally distributed in asymmetrically dividing st...
www.nature.com
April 28, 2025 at 11:02 AM
Read Hien’s fantastic paper on the age-selective apportioning of peroxisomes affecting stem cell fate through metabolism, congratulations Hien 🥳
Reposted by Emilia Kuuluvainen
Tomorrow, welcome!
Welcome to the Stem Cell Seminar April 23rd. Stem cell metabolism of both tissue and pluripotent stem cells on the menu with exiting presentations from @rafabolism.bsky.social and @rutorregrosa.bsky.social @stemmprogram.bsky.social @helsinki.fi @helsinki-biotech.bsky.social @fimm-uh.bsky.social
April 22, 2025 at 10:02 AM
Tomorrow, welcome!
Reposted by Emilia Kuuluvainen
Welcome to the Stem Cell Seminar April 23rd. Stem cell metabolism of both tissue and pluripotent stem cells on the menu with exiting presentations from @rafabolism.bsky.social and @rutorregrosa.bsky.social @stemmprogram.bsky.social @helsinki.fi @helsinki-biotech.bsky.social @fimm-uh.bsky.social
April 8, 2025 at 12:22 PM
Welcome to the Stem Cell Seminar April 23rd. Stem cell metabolism of both tissue and pluripotent stem cells on the menu with exiting presentations from @rafabolism.bsky.social and @rutorregrosa.bsky.social @stemmprogram.bsky.social @helsinki.fi @helsinki-biotech.bsky.social @fimm-uh.bsky.social
Reposted by Emilia Kuuluvainen
Tomorrow, welcome! 👇
Welcome to the next Metabolism seminar, March 18th at 9-11 am in Meilahti. Excellent speaker lineup with Kirsi Pietiläinen and Robin Cristofari groups presenting about #obesity #adiposetissue #diet #aging in humans and penguins @helsinki.fi @stemmprogram.bsky.social @helsinki-biotech.bsky.social
March 17, 2025 at 7:28 AM
Tomorrow, welcome! 👇
Another great cross-campus seminar coming up. Be there!
Welcome to the next Metabolism seminar, March 18th at 9-11 am in Meilahti. Excellent speaker lineup with Kirsi Pietiläinen and Robin Cristofari groups presenting about #obesity #adiposetissue #diet #aging in humans and penguins @helsinki.fi @stemmprogram.bsky.social @helsinki-biotech.bsky.social
March 10, 2025 at 11:47 AM
Another great cross-campus seminar coming up. Be there!
Reposted by Emilia Kuuluvainen
News from our CoE by @katajistolab.bsky.social @sharifiqbal.bsky.social shed light on how the intestinal epithelium is repaired after injury, with implications for aging and chemotherapy-induced damage www.sciencedirect.com/science/arti... @helsinki.fi @helsinki-biotech.bsky.social Congratulations 🎉
Fetal-like reversion in the regenerating intestine is regulated by mesenchymal asporin
Mesenchymal cells and the extracellular matrix (ECM) support epithelium during homeostasis and regeneration. However, the role of the mesenchyme in ep…
www.sciencedirect.com
March 7, 2025 at 12:38 PM
News from our CoE by @katajistolab.bsky.social @sharifiqbal.bsky.social shed light on how the intestinal epithelium is repaired after injury, with implications for aging and chemotherapy-induced damage www.sciencedirect.com/science/arti... @helsinki.fi @helsinki-biotech.bsky.social Congratulations 🎉
Congratulations @sharifiqbal.bsky.social 👏 so happy to see this amazing paper out
1/6 Proudly presenting Sharif’s @sharifiqbal.bsky.social paper on the role of Asporin in intestinal regeneration through TGF-B-dependent fetal-like reversion www.sciencedirect.com/science/arti... out in @cp-cellstemcell.bsky.social @pekka-katajisto.bsky.social @helsinki.fi @metastem.bsky.social 🧵
Fetal-like reversion in the regenerating intestine is regulated by mesenchymal asporin
Mesenchymal cells and the extracellular matrix (ECM) support epithelium during homeostasis and regeneration. However, the role of the mesenchyme in ep…
www.sciencedirect.com
March 7, 2025 at 1:43 PM
Congratulations @sharifiqbal.bsky.social 👏 so happy to see this amazing paper out
Reposted by Emilia Kuuluvainen
Next MetaStem PhD defense this Friday Feb 21st when Hossam Montaser from @otonkoskit.bsky.social lab takes the stage discussing his work on Modelling ER stress-induced Diabetes Using stem cell-derived islets with opponent Professor Carmella Evans-Molina 🎩 👏@stemmprogram.bsky.social @helsinki.fi
February 20, 2025 at 6:28 AM
Next MetaStem PhD defense this Friday Feb 21st when Hossam Montaser from @otonkoskit.bsky.social lab takes the stage discussing his work on Modelling ER stress-induced Diabetes Using stem cell-derived islets with opponent Professor Carmella Evans-Molina 🎩 👏@stemmprogram.bsky.social @helsinki.fi
Reposted by Emilia Kuuluvainen
Excited that Pekka is presenting at @CellSymposia Metabolites: Organellar Communication in Health and Disease this May 11–13, 2025, in Sitges, Spain!
The abstract submission deadline has been extended until Feb 14th. Hope to see you at #CSMetabolites2025
cell-symposia.com/metabolites-...
The abstract submission deadline has been extended until Feb 14th. Hope to see you at #CSMetabolites2025
cell-symposia.com/metabolites-...
Home – Cell Symposia: Metabolites: organellar communication in health and disease
Cell Symposia: Metabolites: organellar communication in health and disease
cell-symposia.com
January 30, 2025 at 7:12 AM
Excited that Pekka is presenting at @CellSymposia Metabolites: Organellar Communication in Health and Disease this May 11–13, 2025, in Sitges, Spain!
The abstract submission deadline has been extended until Feb 14th. Hope to see you at #CSMetabolites2025
cell-symposia.com/metabolites-...
The abstract submission deadline has been extended until Feb 14th. Hope to see you at #CSMetabolites2025
cell-symposia.com/metabolites-...
Another exciting Stem Cell Seminar tomorrow. Welcome!
January 22, 2025 at 6:49 AM
Another exciting Stem Cell Seminar tomorrow. Welcome!
This Friday, welcome!
One more seminar to organize this year: Welcome to the next Metabolism Seminar, next week Friday the 13th. Excited to have Elina Ikonen and Juha Klefström labs presenting in Viikki. As always, credits for students and coffee and pulla for all
December 11, 2024 at 6:03 AM
This Friday, welcome!
One more seminar to organize this year: Welcome to the next Metabolism Seminar, next week Friday the 13th. Excited to have Elina Ikonen and Juha Klefström labs presenting in Viikki. As always, credits for students and coffee and pulla for all
December 2, 2024 at 1:05 PM
One more seminar to organize this year: Welcome to the next Metabolism Seminar, next week Friday the 13th. Excited to have Elina Ikonen and Juha Klefström labs presenting in Viikki. As always, credits for students and coffee and pulla for all
Another great Stem Cell Seminar coming up in two days on Nov 27th when @seollila.bsky.social and @emmihelle.bsky.social share their work. Welcome!
November 25, 2024 at 6:41 PM
Another great Stem Cell Seminar coming up in two days on Nov 27th when @seollila.bsky.social and @emmihelle.bsky.social share their work. Welcome!