Elias Copin
@eliascopin.bsky.social
PhD student with the Quantitative Stem Cell Biology lab at the Francis Crick Institute.
Interested in the cell cycle/cell fate interplay during early development.
Interested in the cell cycle/cell fate interplay during early development.
Reposted by Elias Copin
Thank you to @cp-devcell.bsky.social for selecting our story to feature on the cover of today’s issue of Developmental Cell!
Thank you to Zoë Ruiz for the wonderful art work! Read more here: www.cell.com/developmenta...
Thank you to Zoë Ruiz for the wonderful art work! Read more here: www.cell.com/developmenta...
December 1, 2025 at 7:17 PM
Thank you to @cp-devcell.bsky.social for selecting our story to feature on the cover of today’s issue of Developmental Cell!
Thank you to Zoë Ruiz for the wonderful art work! Read more here: www.cell.com/developmenta...
Thank you to Zoë Ruiz for the wonderful art work! Read more here: www.cell.com/developmenta...
Reposted by Elias Copin
The Crick PhD program is open and there are amazing projects including our lab's. I couldn't recommend enough joining the program: brilliant community and excellent training and mentorship.
Specific project with us will be decided based on your interests.
Apply here www.crick.ac.uk/careers-stud...
Specific project with us will be decided based on your interests.
Apply here www.crick.ac.uk/careers-stud...
October 17, 2025 at 5:36 PM
The Crick PhD program is open and there are amazing projects including our lab's. I couldn't recommend enough joining the program: brilliant community and excellent training and mentorship.
Specific project with us will be decided based on your interests.
Apply here www.crick.ac.uk/careers-stud...
Specific project with us will be decided based on your interests.
Apply here www.crick.ac.uk/careers-stud...
Reposted by Elias Copin
Very sad news, John Gurdon has died.
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
www.magd.cam.ac.uk
October 7, 2025 at 4:02 PM
Very sad news, John Gurdon has died.
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
A developmental biologist's developmental biologist, Nobel prize winner
His work is the foundation of much of today's dev & stem cell bio.
An inspiration to many, including me. Always asking questions & wanting the answers
www.magd.cam.ac.uk/news/profess...
Reposted by Elias Copin
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology
McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.
www.nature.com
September 29, 2025 at 4:45 PM
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
Reposted by Elias Copin
Researchers have found that early embryonic cells start to specialise via converging developmental paths, rather than following linear trajectories as was previously believed.
www.crick.ac.uk/news/2025-09...
www.crick.ac.uk/news/2025-09...
Converging development: how cell paths unite in the embryo
By tracking the fate of individual embryonic stem cells, researchers have found that endoderm cells – early embryonic cells that give rise to tissues such as the gut and lungs – originate from multipl...
www.crick.ac.uk
September 10, 2025 at 9:29 AM
Researchers have found that early embryonic cells start to specialise via converging developmental paths, rather than following linear trajectories as was previously believed.
www.crick.ac.uk/news/2025-09...
www.crick.ac.uk/news/2025-09...
Check out @oliveringe.bsky.social's beautiful work on endoderm specification - super thankful to have been involved with this story!
1/7 Really happy to see my PhD work published in ✨Developmental Cell✨ today! We find human endoderm is specified by two developmental trajectories 🔀, and the choice between alternate routes is dictated by the combinatorial BMP4/Activin signalling. www.cell.com/developmenta...
Combinatorial BMP4 and activin direct the choice between alternate routes to endoderm in a stem cell model of human gastrulation
Inge et al. show that human endoderm originates from two converging developmental
routes with distinct dynamics and efficiencies yet similar developmental potential.
Combinatorial activin and BMP4 sig...
www.cell.com
September 9, 2025 at 10:04 PM
Check out @oliveringe.bsky.social's beautiful work on endoderm specification - super thankful to have been involved with this story!
Reposted by Elias Copin
Nature research paper: Spatiotemporal orchestration of mitosis by cyclin-dependent kinase
https://go.nature.com/444lRhe
https://go.nature.com/444lRhe
Spatiotemporal orchestration of mitosis by cyclin-dependent kinase - Nature
Experiments in fission yeast show that cyclin-dependent kinase is first activated in the nucleus, from which the mitotic signal is propagated from CDK at the centrosome to the cytoplasm.
go.nature.com
June 25, 2025 at 5:50 PM
Nature research paper: Spatiotemporal orchestration of mitosis by cyclin-dependent kinase
https://go.nature.com/444lRhe
https://go.nature.com/444lRhe
Reposted by Elias Copin
If you are going to sunny California to the Salk Cell Cycle meeting don't miss @eliascopin.bsky.social's talk! Elias is our cell cycle and cell fate enthusiast and his presenting new exciting results. Come and say hi! I wish i was there too - it is going to be a fantastic meeting!!
June 20, 2025 at 8:05 AM
If you are going to sunny California to the Salk Cell Cycle meeting don't miss @eliascopin.bsky.social's talk! Elias is our cell cycle and cell fate enthusiast and his presenting new exciting results. Come and say hi! I wish i was there too - it is going to be a fantastic meeting!!
Reposted by Elias Copin
The sacs grew to roughly 2 centimeters wide and could be used to study early pregnancy
https://go.nature.com/43jmUrY
https://go.nature.com/43jmUrY
Stem cells coaxed into most advanced amniotic sacs ever grown in the lab
Nature - The sacs grew to roughly 2 centimeters wide and could be used to study early pregnancy.
go.nature.com
May 18, 2025 at 5:34 PM
The sacs grew to roughly 2 centimeters wide and could be used to study early pregnancy
https://go.nature.com/43jmUrY
https://go.nature.com/43jmUrY
New paper from @santoslab.bsky.social lab. Huge congrats to @borzogharibi.bsky.social & @oliveringe.bsky.social for this amazing work!
Now online! Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development
Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development
An embryonic stem cell-based 3D model that accurately recapitulates the size, morphology, and functional features of the human amnion at 4 weeks, termed the post-gastrulation amnioid (PGA), is developed. The model’s reproducibility and scalability make it ideal for studying amniogenesis and for clinical applications that use human amniotic sac membranes.
dlvr.it
May 15, 2025 at 4:09 PM
New paper from @santoslab.bsky.social lab. Huge congrats to @borzogharibi.bsky.social & @oliveringe.bsky.social for this amazing work!
Reposted by Elias Copin
Registration and abstract submission for YEN 2025 is officially open!
We are looking forward to seeing you at the 17th Young Embryologist Network Conference on the 19th May 2025.
Attendence is FREE thanks to our amazing sponsors: @biologists.bsky.social @10xgenomics.bsky.social and Azenta.
We are looking forward to seeing you at the 17th Young Embryologist Network Conference on the 19th May 2025.
Attendence is FREE thanks to our amazing sponsors: @biologists.bsky.social @10xgenomics.bsky.social and Azenta.
January 30, 2025 at 4:36 PM
Registration and abstract submission for YEN 2025 is officially open!
We are looking forward to seeing you at the 17th Young Embryologist Network Conference on the 19th May 2025.
Attendence is FREE thanks to our amazing sponsors: @biologists.bsky.social @10xgenomics.bsky.social and Azenta.
We are looking forward to seeing you at the 17th Young Embryologist Network Conference on the 19th May 2025.
Attendence is FREE thanks to our amazing sponsors: @biologists.bsky.social @10xgenomics.bsky.social and Azenta.