Egill Richard
@egillrichard.bsky.social
Post Doc in Sam Sternberg lab at Columbia University
Genetics - Microbiology
Genetics - Microbiology
Reposted by Egill Richard
1/9 Metagenomics lets us read microbiomes in nature without cultivation, but writing (editing) them in their native context is still a major challenge.
Meet MetaEdit: a platform for pathway-scale metagenomic editing inside the gut microbiome. science.org/doi/10.1126/...
Meet MetaEdit: a platform for pathway-scale metagenomic editing inside the gut microbiome. science.org/doi/10.1126/...
Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases
Although metagenomic sequencing has revealed a rich microbial biodiversity in the mammalian gut, methods to genetically alter specific species in the microbiome are highly limited. Here, we introduce ...
science.org
November 14, 2025 at 2:25 PM
1/9 Metagenomics lets us read microbiomes in nature without cultivation, but writing (editing) them in their native context is still a major challenge.
Meet MetaEdit: a platform for pathway-scale metagenomic editing inside the gut microbiome. science.org/doi/10.1126/...
Meet MetaEdit: a platform for pathway-scale metagenomic editing inside the gut microbiome. science.org/doi/10.1126/...
Excited to share the work that’s been on my mind for the past 2 years, now on bioRxiv!
Led with Matt Walker, and my first project in the Sternberg Lab .
Check it out ⬇️
tinyurl.com/mshwjd77
Led with Matt Walker, and my first project in the Sternberg Lab .
Check it out ⬇️
tinyurl.com/mshwjd77
Temperate phages enhance host fitness via RNA-guided flagellar remodeling
Bacterial flagella drive motility and chemotaxis while also playing critical roles in host-pathogen interactions, as their oligomeric subunit, flagellin, is specifically recognized by the mammalian im...
tinyurl.com
July 28, 2025 at 3:16 PM
Excited to share the work that’s been on my mind for the past 2 years, now on bioRxiv!
Led with Matt Walker, and my first project in the Sternberg Lab .
Check it out ⬇️
tinyurl.com/mshwjd77
Led with Matt Walker, and my first project in the Sternberg Lab .
Check it out ⬇️
tinyurl.com/mshwjd77
Reposted by Egill Richard
1/16 New pre-print from the Sternberg Lab!
We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness.
Find the preprint and full story here: tinyurl.com/mshwjd77
We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness.
Find the preprint and full story here: tinyurl.com/mshwjd77
July 24, 2025 at 7:58 PM
1/16 New pre-print from the Sternberg Lab!
We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness.
Find the preprint and full story here: tinyurl.com/mshwjd77
We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness.
Find the preprint and full story here: tinyurl.com/mshwjd77
Reposted by Egill Richard
Our paper is published back2back with one from @amazeld.bsky.social and @epcrocha.bsky.social labs where @baptistedarracq.bsky.social, @eloilittner.bsky.social and co. show that Sedentary Chromosomal Integrons are biobanks of phage defense systems. www.science.org/doi/10.1126/...
Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems
Integrons are genetic systems that drive bacterial adaptation by acquiring, expressing, and shuffling gene cassettes. While mobile integrons are well known for spreading antibiotic resistance genes, t...
www.science.org
May 8, 2025 at 8:27 PM
Our paper is published back2back with one from @amazeld.bsky.social and @epcrocha.bsky.social labs where @baptistedarracq.bsky.social, @eloilittner.bsky.social and co. show that Sedentary Chromosomal Integrons are biobanks of phage defense systems. www.science.org/doi/10.1126/...
Reposted by Egill Richard
Please repost: Postdoc position in antibiotic discovery in a large multidisciplinary project combining high-throughput approaches, microscopy, AI, and hit-to-lead optimization at @umontreal.ca and @mila-quebec.bsky.social. Apply to ML.Antibiotics@gmail.com. See
lnkd.in/dVVk4N3s. #microsky
lnkd.in/dVVk4N3s. #microsky
March 12, 2025 at 12:36 PM
Please repost: Postdoc position in antibiotic discovery in a large multidisciplinary project combining high-throughput approaches, microscopy, AI, and hit-to-lead optimization at @umontreal.ca and @mila-quebec.bsky.social. Apply to ML.Antibiotics@gmail.com. See
lnkd.in/dVVk4N3s. #microsky
lnkd.in/dVVk4N3s. #microsky
Reposted by Egill Richard
Viral coat proteins are perceived by the RING1–IBR–RING2-type ubiquitin ligase (RBRL) #PlantSci #Ubiquitin #proteostasis
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Perception of viral infections and initiation of antiviral defence in rice - Nature
Viral coat proteins are perceived by the RING1–IBR–RING2-type ubiquitin ligase, initiating the first step of the natural antiviral response in rice.
www.nature.com
March 13, 2025 at 7:21 AM
Viral coat proteins are perceived by the RING1–IBR–RING2-type ubiquitin ligase (RBRL) #PlantSci #Ubiquitin #proteostasis
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Egill Richard
And its out! New paper for #integron aficionados. We found gene-less cassettes in superintegrons that express/silence other cassettes in the array. Here is a 🧵(if I know how to do this in Bluesky...😆)
academic.oup.com/nar/advance-...
academic.oup.com/nar/advance-...
Identification of promoter activity in gene-less cassettes from Vibrionaceae superintegrons
Abstract. Integrons are genetic platforms that acquire new genes encoded in integron cassettes (ICs), building arrays of adaptive functions. ICs generally encod
academic.oup.com
January 15, 2024 at 7:50 PM
And its out! New paper for #integron aficionados. We found gene-less cassettes in superintegrons that express/silence other cassettes in the array. Here is a 🧵(if I know how to do this in Bluesky...😆)
academic.oup.com/nar/advance-...
academic.oup.com/nar/advance-...