Dave Natale
@drcnatale.bsky.social
Associate professor - Queen’s University
Placenta researcher studying trophoblast stem cells and fetal growth restriction using cell culture and rodent models of placental pathology
Views are my own
Placenta researcher studying trophoblast stem cells and fetal growth restriction using cell culture and rodent models of placental pathology
Views are my own
Thrilled to see this work published!
Congratulations Jessie, Bry and Dan!
Congratulations Jessie, Bry and Dan!
More work by an amazing team looking at how Delta 9-Tetrahydrocannabinol Signaling Through Cannabinoid Receptor 1 Alters Trophoblast Differentiation. Out today in Stem Cells and Development! journals.sagepub.com/doi/10.1177/...
Congratulations Jessie on your hard work! @drcnatale.bsky.social
Congratulations Jessie on your hard work! @drcnatale.bsky.social
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
November 7, 2025 at 5:29 AM
Thrilled to see this work published!
Congratulations Jessie, Bry and Dan!
Congratulations Jessie, Bry and Dan!
Excited to share the latest work from our lab investigating human placental pericytes!
Checkout our new work demonstrating how TGFb1 impacts placental pericyte secretion of proangiogenic and proinflammatory factors and inhibits pericyte phagocytosis. Out today in Scientific Reports. @drcnatale.bsky.social
#pericytes #placenta
www.nature.com/articles/s41...
#pericytes #placenta
www.nature.com/articles/s41...
The regulation of placental pericyte function through transforming growth factor β-1 signalling - Scientific Reports
Scientific Reports - The regulation of placental pericyte function through transforming growth factor β-1 signalling
www.nature.com
October 22, 2025 at 3:04 PM
Excited to share the latest work from our lab investigating human placental pericytes!
Reposted by Dave Natale
Full paper link: tinyurl.com/vcp23d95
Exploring the differentiation potential of EomesPOS mouse trophoblast cells in mid-gestation
Mouse trophoblast stem (mTS) cells can be derived from the blastocyst or extraembryonic ectoderm as late as embryonic day (E) 6.5 and when cultured in…
tinyurl.com
October 6, 2025 at 11:43 AM
Full paper link: tinyurl.com/vcp23d95
Reposted by Dave Natale
#DBfeature
Lineage tracing of Eomes-positive mouse trophoblast cells confirms their capacity to contribute to both placental layers in vivo even after E7.5
-Avery McGinnis, Megan Cull, Nichole Peterson, Matthew Tang, Bryony Natale @bnatale.bsky.social, David Natale
#Extraembryonic
Lineage tracing of Eomes-positive mouse trophoblast cells confirms their capacity to contribute to both placental layers in vivo even after E7.5
-Avery McGinnis, Megan Cull, Nichole Peterson, Matthew Tang, Bryony Natale @bnatale.bsky.social, David Natale
#Extraembryonic
October 6, 2025 at 11:43 AM
#DBfeature
Lineage tracing of Eomes-positive mouse trophoblast cells confirms their capacity to contribute to both placental layers in vivo even after E7.5
-Avery McGinnis, Megan Cull, Nichole Peterson, Matthew Tang, Bryony Natale @bnatale.bsky.social, David Natale
#Extraembryonic
Lineage tracing of Eomes-positive mouse trophoblast cells confirms their capacity to contribute to both placental layers in vivo even after E7.5
-Avery McGinnis, Megan Cull, Nichole Peterson, Matthew Tang, Bryony Natale @bnatale.bsky.social, David Natale
#Extraembryonic
Reposted by Dave Natale
Excited to see my MSc student Andrea Kocsis’ BOR publication identifying THC-specific placental markers of #schizophrenia academic.oup.com/biolreprod/a... #cannabis #placenta @drcnatale.bsky.social @schulichmeddent.bsky.social @sriwomenshealth.bsky.social @placentadoc.bsky.social
Identifying established human placental markers of schizophrenia in rodents after gestational ∆9-tetrahydrocannabinol exposure†
Summary Sentence Prenatal THC exposure led to alterations in the expression of established prioritized markers of schizophrenia in placenta and brain model
academic.oup.com
September 12, 2025 at 10:42 AM
Excited to see my MSc student Andrea Kocsis’ BOR publication identifying THC-specific placental markers of #schizophrenia academic.oup.com/biolreprod/a... #cannabis #placenta @drcnatale.bsky.social @schulichmeddent.bsky.social @sriwomenshealth.bsky.social @placentadoc.bsky.social
Reposted by Dave Natale
🔊Share widely!
Were looking for a Tier 2 CRC in Human Metabolic Disease!
Just posted but hurry as app deadline is May 15!
Got expertise in #obesity or #diabetes and are an emerging expert in your field?
Apply now!!!!
carleton.ca/deputyprovos...
Were looking for a Tier 2 CRC in Human Metabolic Disease!
Just posted but hurry as app deadline is May 15!
Got expertise in #obesity or #diabetes and are an emerging expert in your field?
Apply now!!!!
carleton.ca/deputyprovos...
Assistant or Associate Professor and Canada Research Chair, Tier 2, Biology or Health Sciences or Neuroscience (Human Metabolic Disease) - Office of the Deputy Provost (Academic Operations and Plannin...
About the Position The Faculty of Science invites applications for a Canadian Institute of Health Research (CIHR) Tier 2 Canada Research Chair (CRC) appointment in Biology, as applicable to Human Meta...
carleton.ca
April 8, 2025 at 10:44 PM
🔊Share widely!
Were looking for a Tier 2 CRC in Human Metabolic Disease!
Just posted but hurry as app deadline is May 15!
Got expertise in #obesity or #diabetes and are an emerging expert in your field?
Apply now!!!!
carleton.ca/deputyprovos...
Were looking for a Tier 2 CRC in Human Metabolic Disease!
Just posted but hurry as app deadline is May 15!
Got expertise in #obesity or #diabetes and are an emerging expert in your field?
Apply now!!!!
carleton.ca/deputyprovos...
Reposted by Dave Natale
Thanks @westernu.bsky.social for your continued support of our research!
A study led by #WesternU's Schulich School of Medicine & Dentistry professor Dan Hardy is the first to uncover the potential of Omega-3 to counteract the effects of THC in offspring - from low birth weight to heart complications - after exposure to cannabis in utero.
Western research shows Omega-3 potential against THC - Western News
Widely available supplement, Omega-3, shows promise in protecting against negative fetal effects, including compromised heart health, due to THC exposure.
buff.ly
April 8, 2025 at 2:05 PM
Thanks @westernu.bsky.social for your continued support of our research!
Reposted by Dave Natale
Omega-3s have potential to counteract THC effects on fetal development
"The best way to prevent the adverse cardiac health outcomes in offspring is to stop using cannabis, but this study raises the exciting possibility that an Omega-3 diet could be beneficial to those…exposed to cannabis in utero."
"The best way to prevent the adverse cardiac health outcomes in offspring is to stop using cannabis, but this study raises the exciting possibility that an Omega-3 diet could be beneficial to those…exposed to cannabis in utero."
Omega-3s have potential to counteract THC effects on fetal development, study finds
Previous studies show exposure to Tetrahydrocannabinol (THC)—the main psychoactive component in cannabis—while in utero can lead to lower birth weight and potential heart complications in newborn anim...
medicalxpress.com
April 4, 2025 at 2:57 PM
Omega-3s have potential to counteract THC effects on fetal development
"The best way to prevent the adverse cardiac health outcomes in offspring is to stop using cannabis, but this study raises the exciting possibility that an Omega-3 diet could be beneficial to those…exposed to cannabis in utero."
"The best way to prevent the adverse cardiac health outcomes in offspring is to stop using cannabis, but this study raises the exciting possibility that an Omega-3 diet could be beneficial to those…exposed to cannabis in utero."
Congratulations Matthew, Caelan, Daniel, Sophia on your spectacular posters! What a way to finish up your fourth year projects!
Congrats as well to all the students who presented over the past three days - wonderful job and amazing studies!
@queensuglobal.bsky.social
Congrats as well to all the students who presented over the past three days - wonderful job and amazing studies!
@queensuglobal.bsky.social
April 4, 2025 at 3:34 PM
Congratulations Matthew, Caelan, Daniel, Sophia on your spectacular posters! What a way to finish up your fourth year projects!
Congrats as well to all the students who presented over the past three days - wonderful job and amazing studies!
@queensuglobal.bsky.social
Congrats as well to all the students who presented over the past three days - wonderful job and amazing studies!
@queensuglobal.bsky.social
Reposted by Dave Natale
A huge thank you to everyone who joined us at the 2025 SRI Annual Scientific Meeting!
With over 1,000 attendees from more than 30 countries, this year’s meeting was an incredible success.
📸 Keep an eye out for the SRI 2025 photo album coming soon!
#SRI2025
With over 1,000 attendees from more than 30 countries, this year’s meeting was an incredible success.
📸 Keep an eye out for the SRI 2025 photo album coming soon!
#SRI2025
April 1, 2025 at 8:00 PM
A huge thank you to everyone who joined us at the 2025 SRI Annual Scientific Meeting!
With over 1,000 attendees from more than 30 countries, this year’s meeting was an incredible success.
📸 Keep an eye out for the SRI 2025 photo album coming soon!
#SRI2025
With over 1,000 attendees from more than 30 countries, this year’s meeting was an incredible success.
📸 Keep an eye out for the SRI 2025 photo album coming soon!
#SRI2025
Congratulations Caelan on your spectacular poster presentation at SRI in Charlotte, NC today!!! Amazing job and an awesome meeting!
@queensuglobal.bsky.social @sriwomenshealth.bsky.social
@queensuglobal.bsky.social @sriwomenshealth.bsky.social
March 29, 2025 at 1:49 AM
Congratulations Caelan on your spectacular poster presentation at SRI in Charlotte, NC today!!! Amazing job and an awesome meeting!
@queensuglobal.bsky.social @sriwomenshealth.bsky.social
@queensuglobal.bsky.social @sriwomenshealth.bsky.social
Great session today!
Thank you @sriwomenshealth.bsky.social for the opportunity to present our work!!
Thank you @sriwomenshealth.bsky.social for the opportunity to present our work!!
Great presentation by @drcnatale.bsky.social on the effects of cannabinoids on the placenta vasculature @sriwomenshealth.bsky.social #SRI2025
March 28, 2025 at 3:08 AM
Great session today!
Thank you @sriwomenshealth.bsky.social for the opportunity to present our work!!
Thank you @sriwomenshealth.bsky.social for the opportunity to present our work!!
Reposted by Dave Natale
My alma mater, the University of British Columbia, Dept of Medical Genetics, is hiring for a tenure track junior faculty position specializing in chromatin regulation / gene regulatory mechanisms. Beautiful city and vibrant epigenetics research. Please share!
medgen.med.ubc.ca/assistant-pr...
medgen.med.ubc.ca/assistant-pr...
Assistant Professor (Tenure-Track) | Department of Medical Genetics | Life Sciences Institute (LSI) - Department of Medical Genetics
The Department of Medical Genetics, in collaboration with the Life Sciences Institute (LSI), invites applications for a full-time faculty position at the rank of Assistant Professor, tenure track with...
medgen.med.ubc.ca
March 4, 2025 at 2:36 AM
My alma mater, the University of British Columbia, Dept of Medical Genetics, is hiring for a tenure track junior faculty position specializing in chromatin regulation / gene regulatory mechanisms. Beautiful city and vibrant epigenetics research. Please share!
medgen.med.ubc.ca/assistant-pr...
medgen.med.ubc.ca/assistant-pr...
Excited to share the latest work from our lab - published in @devbiol.bsky.social!
can01.safelinks.protection.outlook.com?url=https%3A...
Congratulations Avery, @bnatale.bsky.social , Matthew Tang, Megan Cull and Nicki Peterson!
can01.safelinks.protection.outlook.com?url=https%3A...
Congratulations Avery, @bnatale.bsky.social , Matthew Tang, Megan Cull and Nicki Peterson!
February 18, 2025 at 10:16 PM
Excited to share the latest work from our lab - published in @devbiol.bsky.social!
can01.safelinks.protection.outlook.com?url=https%3A...
Congratulations Avery, @bnatale.bsky.social , Matthew Tang, Megan Cull and Nicki Peterson!
can01.safelinks.protection.outlook.com?url=https%3A...
Congratulations Avery, @bnatale.bsky.social , Matthew Tang, Megan Cull and Nicki Peterson!
Reposted by Dave Natale
Exploring the differentiation potential of EomesPOS mouse trophoblast cells in mid-gestation
#trophoblaststemcells #lineagetracing
Congratulations McGinnis et al, @drcnatale.bsky.social
www.sciencedirect.com/science/arti...
#trophoblaststemcells #lineagetracing
Congratulations McGinnis et al, @drcnatale.bsky.social
www.sciencedirect.com/science/arti...
Exploring the differentiation potential of EomesPOS mouse trophoblast cells in mid-gestation
Mouse trophoblast stem (mTS) cells can be derived from the blastocyst or extraembryonic ectoderm as late as embryonic day (E) 6.5 and when cultured in…
www.sciencedirect.com
February 17, 2025 at 4:21 PM
Exploring the differentiation potential of EomesPOS mouse trophoblast cells in mid-gestation
#trophoblaststemcells #lineagetracing
Congratulations McGinnis et al, @drcnatale.bsky.social
www.sciencedirect.com/science/arti...
#trophoblaststemcells #lineagetracing
Congratulations McGinnis et al, @drcnatale.bsky.social
www.sciencedirect.com/science/arti...