@dpminde.bsky.social
Reposted
We are introducing LipiGo 🤗
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
November 4, 2025 at 1:55 PM
We are introducing LipiGo 🤗
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
(Contains some of the most comprehensive LNP corona proteomics data on Pride: www.ebi.ac.uk/pride/archiv... )
January 14, 2025 at 5:49 PM
(Contains some of the most comprehensive LNP corona proteomics data on Pride: www.ebi.ac.uk/pride/archiv... )
Minimal steps, Great IDs, cool stuff... Congrats!
Robust collection and processing for label-free single voxel proteomics www.nature.com/artic...
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#proteomics #prot-paper
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#proteomics #prot-paper
January 14, 2025 at 2:48 PM
Minimal steps, Great IDs, cool stuff... Congrats!
Happy to see this beautiful piece on nanoparticle imaging and related omics coming out now. Includes some of the most comprehensive nanoparticle proteomics data: www.ebi.ac.uk/pride/archiv...
January 14, 2025 at 1:39 PM
Happy to see this beautiful piece on nanoparticle imaging and related omics coming out now. Includes some of the most comprehensive nanoparticle proteomics data: www.ebi.ac.uk/pride/archiv...
Reposted
Dear authors, please have mercy on reviewers that are reading your paper on a laptop in a train or plane. It helps a lot if figures are located just after the first mention in text, and the figure legend is directly underneath. Nature & Cell & many other journals allow that.
November 22, 2024 at 10:45 AM
Dear authors, please have mercy on reviewers that are reading your paper on a laptop in a train or plane. It helps a lot if figures are located just after the first mention in text, and the figure legend is directly underneath. Nature & Cell & many other journals allow that.
Reposted
After long-time review, #nanoSPLITS is finally published. I am deeply grateful to my colleagues who made this work possible, especially @cajunscience.bsky.social. I am also grateful to the support of our single-cell proteomics community during the peer review on Nature Communication!
Now this is a paper I had long been waiting for! NanoSPLITS is out! Parallel single cell proteomic and transcriptomic measurements from the same cell! Great work from @cajunscience.bsky.social and @nanopots.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting - Nature Communications
Single-cell multiomics can provide broad insights into gene/protein regulatory networks and cellular diversity. Here, authors develop nanoSPLITS, a nanodroplet splitting approach for global profiling ...
www.nature.com
December 6, 2024 at 12:41 AM
After long-time review, #nanoSPLITS is finally published. I am deeply grateful to my colleagues who made this work possible, especially @cajunscience.bsky.social. I am also grateful to the support of our single-cell proteomics community during the peer review on Nature Communication!
Reposted
Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf
December 5, 2024 at 3:43 PM
Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf
Reposted
Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵Your weekend read👇
@cellpress.bsky.social
cell.com/cell-host-mi...
@cellpress.bsky.social
cell.com/cell-host-mi...
November 29, 2024 at 4:01 PM
Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵Your weekend read👇
@cellpress.bsky.social
cell.com/cell-host-mi...
@cellpress.bsky.social
cell.com/cell-host-mi...
Reposted
