Dervis Salih
@dervissalih1.bsky.social
Scientist studying molecular links between Alzheimer's, Ageing, microglia & diet @UCL @UKDRI @ARUKnews #Dementia Trained @BabrahamInst @Cambridge_uni @Stanford
Pinned
Dervis Salih
@dervissalih1.bsky.social
· Nov 16
Choose Life. Choose a job. Choose a career. Choose peace. Choose a purpose. Choose fucking climate change, choose vaccines, learning, fairness and taxes. Choose education, tofu, and the NHS. Choose choice, honesty, mince pies, electric cars. Choose free school meals. Choose truth.
"Theatricality and deception - powerful agents to the uninitiated." "Oh, you think darkness is your ally." "The shadows betray you because they belong to me." Joe Marler was the ONLY one that worked it out #CelebrityTraitors
November 7, 2025 at 8:22 PM
"Theatricality and deception - powerful agents to the uninitiated." "Oh, you think darkness is your ally." "The shadows betray you because they belong to me." Joe Marler was the ONLY one that worked it out #CelebrityTraitors
Reposted by Dervis Salih
trickle down economics
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November 1, 2025 at 1:31 AM
trickle down economics
trickle down economic
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trickle down economic
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Reposted by Dervis Salih
Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease https://www.biorxiv.org/content/10.1101/2025.08.25.671921v1
August 28, 2025 at 4:15 PM
Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease https://www.biorxiv.org/content/10.1101/2025.08.25.671921v1
Out now on biorxiv! Excited to share our latest collaborative work investigating the earliest stages of Parkinson’s disease.
www.biorxiv.org/content/10.1...
Thanks to all the amazing co-authors Melissa Grant-Peters @jsbeckwith.bsky.social @stevethechemist.bsky.social Mina Ryten Sonia Gandhi
www.biorxiv.org/content/10.1...
Thanks to all the amazing co-authors Melissa Grant-Peters @jsbeckwith.bsky.social @stevethechemist.bsky.social Mina Ryten Sonia Gandhi
Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease
Parkinson's disease (PD) is characterised by insoluble α-synuclein (αSyn) aggregates in Lewy bodies (LBs) within the substantia nigra, with cortical pathology appearing as the disease progresses. Late...
www.biorxiv.org
November 1, 2025 at 1:33 PM
Reposted by Dervis Salih
TDP-43 loss of function drives aberrant splicing in Parkinson's disease https://www.biorxiv.org/content/10.1101/2025.09.04.673943v1
September 9, 2025 at 7:16 PM
TDP-43 loss of function drives aberrant splicing in Parkinson's disease https://www.biorxiv.org/content/10.1101/2025.09.04.673943v1
Reposted by Dervis Salih
Dear Friends and Colleagues, we are finally on Bluesky!
Our lab uses human stem cell models to understand brain, spinal cord and peripheral nerve diseases, focusing on RNA metabolism and cellular autonomy.
We are based at NUS in Singapore at the Life Sciences Institute: www.nus.edu.sg/lsi/
Our lab uses human stem cell models to understand brain, spinal cord and peripheral nerve diseases, focusing on RNA metabolism and cellular autonomy.
We are based at NUS in Singapore at the Life Sciences Institute: www.nus.edu.sg/lsi/
www.nus.edu.sg
September 28, 2025 at 10:57 AM
Dear Friends and Colleagues, we are finally on Bluesky!
Our lab uses human stem cell models to understand brain, spinal cord and peripheral nerve diseases, focusing on RNA metabolism and cellular autonomy.
We are based at NUS in Singapore at the Life Sciences Institute: www.nus.edu.sg/lsi/
Our lab uses human stem cell models to understand brain, spinal cord and peripheral nerve diseases, focusing on RNA metabolism and cellular autonomy.
We are based at NUS in Singapore at the Life Sciences Institute: www.nus.edu.sg/lsi/
Well that was a great idea, a stage organised by @johnkennedydj.bsky.social @radiox.co.uk @themaccabees.bsky.social @allpointseastfest.bsky.social #AllPointsEast featuring Man/Woman/Chainsaw amongst others
August 24, 2025 at 11:28 PM
Well that was a great idea, a stage organised by @johnkennedydj.bsky.social @radiox.co.uk @themaccabees.bsky.social @allpointseastfest.bsky.social #AllPointsEast featuring Man/Woman/Chainsaw amongst others
The calm before the storm @themaccabees.bsky.social @allpointseastfest.bsky.social @radiox.co.uk #AllPointsEast #Maccabees
August 24, 2025 at 3:13 PM
The calm before the storm @themaccabees.bsky.social @allpointseastfest.bsky.social @radiox.co.uk #AllPointsEast #Maccabees
Reposted by Dervis Salih
Excited to share my new book with you. Out now for pre-order: www.penguin.co.uk/books/458539...
March 4, 2025 at 9:04 AM
Excited to share my new book with you. Out now for pre-order: www.penguin.co.uk/books/458539...
Reposted by Dervis Salih
New from the Kinghorn Lab! 🧠🔬 Our latest preprint shows that in fly 🪰🧬 Gaucher’s & Parkinson’s 🧠 models, kidney dysfunction drives neurodegeneration - supporting emerging links between renal health & Parkinson's. You can read it here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Redox Dyshomeostasis Links Renal and Neuronal Dysfunction in Drosophila Models of Gaucher and Parkinson's Disease
Gaucher disease (GD), the most common lysosomal storage disorder, is caused by bi-allelic mutations in the GBA1 gene. Variants in GBA1 also represent the most frequent genetic risk factor for Parkinso...
www.biorxiv.org
August 10, 2025 at 8:10 PM
New from the Kinghorn Lab! 🧠🔬 Our latest preprint shows that in fly 🪰🧬 Gaucher’s & Parkinson’s 🧠 models, kidney dysfunction drives neurodegeneration - supporting emerging links between renal health & Parkinson's. You can read it here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Dervis Salih
Blood Biomarkers: Testing for Alzheimer’s Disease
Professor Jonathan Schott @jmschott.bsky.social (UCL) explains how blood tests are reshaping Alzheimer’s diagnosis. Clear, current and clinically relevant.
Recorded at the Wessex Dementia Research Conference
youtu.be/3fLl1Mzwbsk
Professor Jonathan Schott @jmschott.bsky.social (UCL) explains how blood tests are reshaping Alzheimer’s diagnosis. Clear, current and clinically relevant.
Recorded at the Wessex Dementia Research Conference
youtu.be/3fLl1Mzwbsk
Blood Biomarkers & Testing for Alzheimer’s Disease
YouTube video by Dementia Researcher
youtu.be
August 4, 2025 at 12:37 PM
Blood Biomarkers: Testing for Alzheimer’s Disease
Professor Jonathan Schott @jmschott.bsky.social (UCL) explains how blood tests are reshaping Alzheimer’s diagnosis. Clear, current and clinically relevant.
Recorded at the Wessex Dementia Research Conference
youtu.be/3fLl1Mzwbsk
Professor Jonathan Schott @jmschott.bsky.social (UCL) explains how blood tests are reshaping Alzheimer’s diagnosis. Clear, current and clinically relevant.
Recorded at the Wessex Dementia Research Conference
youtu.be/3fLl1Mzwbsk
Reposted by Dervis Salih
Another fulfilling week for The Greensmith Lab (+ colleagues from other DNMD groups) hosting their annual Work Experience at UCL QSIoN. The Summer Students were able to get a taste of scientific life, with hands-on experience, learning key skills eg. pipetting, cell culture, immunostaining and more!
August 4, 2025 at 9:15 AM
Another fulfilling week for The Greensmith Lab (+ colleagues from other DNMD groups) hosting their annual Work Experience at UCL QSIoN. The Summer Students were able to get a taste of scientific life, with hands-on experience, learning key skills eg. pipetting, cell culture, immunostaining and more!
Congratulations to all colleagues that have worked hard to support the scientific community, and that have been recognised for their efforts. Senior Academic and Early Career Promotions 2024-25 | UCL Faculty of Brain Sciences @uclqsion.bsky.social www.ucl.ac.uk/brain-scienc...
August 3, 2025 at 5:19 PM
Congratulations to all colleagues that have worked hard to support the scientific community, and that have been recognised for their efforts. Senior Academic and Early Career Promotions 2024-25 | UCL Faculty of Brain Sciences @uclqsion.bsky.social www.ucl.ac.uk/brain-scienc...
Reposted by Dervis Salih
Spread the news! We are excited to expand our research team, working on cellular senescence, at the Cancer Research UK Cambridge Institute, University of Cambridge.
jobs.cam.ac.uk/job/52026/
jobs.cam.ac.uk/job/52027/
jobs.cam.ac.uk/job/52026/
jobs.cam.ac.uk/job/52027/
a yellow sign that says we 're hiring
ALT: a yellow sign that says we 're hiring
media.tenor.com
July 25, 2025 at 10:06 PM
Spread the news! We are excited to expand our research team, working on cellular senescence, at the Cancer Research UK Cambridge Institute, University of Cambridge.
jobs.cam.ac.uk/job/52026/
jobs.cam.ac.uk/job/52027/
jobs.cam.ac.uk/job/52026/
jobs.cam.ac.uk/job/52027/
Reposted by Dervis Salih
Cerebral small vessel disease (cSVD) can cause stroke and dementia, but has no cure. With @ukdri.ac.uk, we're supporting a clinical study at @imperialcollegeldn.bsky.social to test whether XBD173, a shelved anxiety drug, can reduce brain damage in people with cSVD.
July 26, 2025 at 9:00 AM
Cerebral small vessel disease (cSVD) can cause stroke and dementia, but has no cure. With @ukdri.ac.uk, we're supporting a clinical study at @imperialcollegeldn.bsky.social to test whether XBD173, a shelved anxiety drug, can reduce brain damage in people with cSVD.
It's cool to live in a country when the Women are better at football than the men #WEURO2025 #Lionesses #EnglandItaly
England through to Women's Euros final after beating Italy in extra time
England through to Women's Euros final after beating Italy in extra time
England have produced another stunning comeback to beat Italy 2-1 in extra time in the semi-finals of the Women's Euros.
news.sky.com
July 22, 2025 at 9:46 PM
It's cool to live in a country when the Women are better at football than the men #WEURO2025 #Lionesses #EnglandItaly
Reposted by Dervis Salih
New preprint. ATF4 activation is thought to lead to longer lifespans. However, our study shows that suppression rather than activation extends lifespan in the fly. New Qs: how we can target ATF4 or its downstream targets to gain targeted longevity benefits.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
July 18, 2025 at 6:57 PM
New preprint. ATF4 activation is thought to lead to longer lifespans. However, our study shows that suppression rather than activation extends lifespan in the fly. New Qs: how we can target ATF4 or its downstream targets to gain targeted longevity benefits.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Dervis Salih
Nonuniversality of inflammaging across human populations
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Nonuniversality of inflammaging across human populations - Nature Aging
Analyzing readouts of inflammaging across four cohorts, Franck and colleagues identify strong variation and observe that inflammaging, in its known form, primarily emerges in industrialized—but not no...
www.nature.com
July 2, 2025 at 12:15 PM
Nonuniversality of inflammaging across human populations
www.nature.com/articles/s43...
www.nature.com/articles/s43...
"Age is just a number, attitude is everything" Fauja Singh is world's oldest marathon runner, & local and national hero and inspiration. Took up running at age of 89 against grief of losing his wife and son. Raised thousands of pounds for charity www.itv.com/news/2025-07...
July 16, 2025 at 6:42 AM
"Age is just a number, attitude is everything" Fauja Singh is world's oldest marathon runner, & local and national hero and inspiration. Took up running at age of 89 against grief of losing his wife and son. Raised thousands of pounds for charity www.itv.com/news/2025-07...
Reposted by Dervis Salih
Research Assistant position at King’s College London. Join the PALLDEM-Homecare project to support homecare for people with dementia. Qualitative research skills required. Closing date: 27th July
www.dementiaresearcher.nihr.ac.uk/job/research...
www.dementiaresearcher.nihr.ac.uk/job/research...
Research Assistant: PALLDEM-Homecare project
Research Assistant position at King’s College London. Join the PALLDEM-Homecare project to support homecare for people with dementia.
www.dementiaresearcher.nihr.ac.uk
July 12, 2025 at 9:13 PM
Research Assistant position at King’s College London. Join the PALLDEM-Homecare project to support homecare for people with dementia. Qualitative research skills required. Closing date: 27th July
www.dementiaresearcher.nihr.ac.uk/job/research...
www.dementiaresearcher.nihr.ac.uk/job/research...
The pick of the London festivals @themaccabees.bsky.social ##AllPointsEast Now with @johnkennedydj.bsky.social @radiox.co.uk stage
July 13, 2025 at 12:18 PM
The pick of the London festivals @themaccabees.bsky.social ##AllPointsEast Now with @johnkennedydj.bsky.social @radiox.co.uk stage
Reposted by Dervis Salih
Working with tricky colleagues? Join us at 12pm BST on Weds 16 July for tips on handling conflict in research with Dr Claire Price & Dr Anna Mallach. Live talk & chat.
communities.dementiaresearcher.nihr.ac.uk/c/events/wor...
communities.dementiaresearcher.nihr.ac.uk/c/events/wor...
Dementia Researcher Community - Working with Difficult People: Strategies for Academic Settings
Dementia Researcher Community - Working with Difficult People: Strategies for Academic Settings
communities.dementiaresearcher.nihr.ac.uk
July 11, 2025 at 10:43 AM
Working with tricky colleagues? Join us at 12pm BST on Weds 16 July for tips on handling conflict in research with Dr Claire Price & Dr Anna Mallach. Live talk & chat.
communities.dementiaresearcher.nihr.ac.uk/c/events/wor...
communities.dementiaresearcher.nihr.ac.uk/c/events/wor...
Amazing opportunity postdocs
The Rajani Lab is hiring! We are looking for a postdoc to join us at @ukdri.ac.uk @edinburgh-uni.bsky.social to investigate neuronal activity and white matter changes in vascular dementia.
Apply here 👇
bit.ly/44AFJHx
Apply here 👇
bit.ly/44AFJHx
Research Fellow
We are looking for a postdoctoral Research Fellow to join the Rajani Lab as part of the new national BHF-UK DRI Centre for Vascular Dementia Research.
bit.ly
July 11, 2025 at 11:21 AM
Amazing opportunity postdocs
Reposted by Dervis Salih
What is the link between rugby and dementia?
A new study of 200 former players aged 30-61, led by Prof David Sharp & Dr Neil Graham, found no cases of early-onset dementia, although some of the group showed potential signs of neurodegeneration👉 buff.ly/JulcQyL
A new study of 200 former players aged 30-61, led by Prof David Sharp & Dr Neil Graham, found no cases of early-onset dementia, although some of the group showed potential signs of neurodegeneration👉 buff.ly/JulcQyL
July 10, 2025 at 4:18 PM
What is the link between rugby and dementia?
A new study of 200 former players aged 30-61, led by Prof David Sharp & Dr Neil Graham, found no cases of early-onset dementia, although some of the group showed potential signs of neurodegeneration👉 buff.ly/JulcQyL
A new study of 200 former players aged 30-61, led by Prof David Sharp & Dr Neil Graham, found no cases of early-onset dementia, although some of the group showed potential signs of neurodegeneration👉 buff.ly/JulcQyL