James R Evans
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jamesrevans.bsky.social
James R Evans
@jamesrevans.bsky.social
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Postdoctoral research fellow at UCL Queen Square Institute of Neurology and the Francis Crick Institute. Former musician.
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Reposted by James R Evans
biorxiv-neursci.bsky.social
TDP-43 loss of function drives aberrant splicing in Parkinson's disease https://www.biorxiv.org/content/10.1101/2025.09.04.673943v1
September 9, 2025 at 7:16 PM
jamesrevans.bsky.social
Out now on biorxiv! Excited to share our latest collaborative work investigating the earliest stages of Parkinson’s disease.

www.biorxiv.org/content/10.1...

Thanks to all the amazing co-authors Melissa Grant-Peters @jsbeckwith.bsky.social @stevethechemist.bsky.social Mina Ryten Sonia Gandhi
Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease
Parkinson's disease (PD) is characterised by insoluble α-synuclein (αSyn) aggregates in Lewy bodies (LBs) within the substantia nigra, with cortical pathology appearing as the disease progresses. Late...
www.biorxiv.org
September 1, 2025 at 9:14 AM
Reposted by James R Evans
biorxiv-neursci.bsky.social
Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease https://www.biorxiv.org/content/10.1101/2025.08.25.671921v1
August 28, 2025 at 4:15 PM