Dilara 🍁
@dayyildiz.bsky.social
Bioinformatician and data steward of Salta Group at Netherlands Institute of Neuroscience
Reposted by Dilara 🍁
🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
October 16, 2025 at 6:23 AM
🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...
www.biorxiv.org/cgi/content/...
Reposted by Dilara 🍁
Our paper has sparked a lot of people asking me – so Keri, what’s the tldr – is there, or isn’t there, new neurons in the human hippocampus?
It's a little more complicated than a yes or no IMO.
It's a little more complicated than a yes or no IMO.
Updated from the preprint, our paper, "Spatiotemporal analysis of gene expression in the human dentate gyrus reveals age-associated changes in cellular maturation and neuroinflammation" is now published.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
April 2, 2025 at 3:07 PM
Our paper has sparked a lot of people asking me – so Keri, what’s the tldr – is there, or isn’t there, new neurons in the human hippocampus?
It's a little more complicated than a yes or no IMO.
It's a little more complicated than a yes or no IMO.
Reposted by Dilara 🍁
Please repost to get the word out! @nkgarg.bsky.social and I are excited to present a personalized feed for academics! It shows posts about papers from accounts you’re following bsky.app/profile/pape...
March 10, 2025 at 3:12 PM
Please repost to get the word out! @nkgarg.bsky.social and I are excited to present a personalized feed for academics! It shows posts about papers from accounts you’re following bsky.app/profile/pape...
Our paper is now live on bioRxiv! 🤩 @giorgitos.bsky.social has done an amazing job breaking it down in this thread. Take a look!
🧵 1/ Excited to share our new research on immature neurons (ImN) in the adult human brain and their roles in healthy aging, Alzheimer’s disease (AD), and cognitive resilience. Here’s what we discovered 👇
Unique transcriptional profiles of adult human immature neurons in healthy aging, Alzheimer's disease, and cognitive resilience https://www.biorxiv.org/content/10.1101/2025.01.08.631686v1
January 10, 2025 at 9:27 AM
Our paper is now live on bioRxiv! 🤩 @giorgitos.bsky.social has done an amazing job breaking it down in this thread. Take a look!
Reposted by Dilara 🍁
it's big, and it's a review of 601 papers on the topic - but here's an update on Neuroinflammation in Alzheimer's Disease
www.nature.com/articles/s41...
led by Michael Heneka, published in @natrevimmunol.bsky.social today
(MANY more authors listed and linked below)
www.nature.com/articles/s41...
led by Michael Heneka, published in @natrevimmunol.bsky.social today
(MANY more authors listed and linked below)
Neuroinflammation in Alzheimer disease - Nature Reviews Immunology
This Review provides an in-depth examination of how inflammation contributes to neurodegeneration in Alzheimer disease. The authors explore the impact of extrinsic factors, such as brain trauma, diet ...
www.nature.com
December 10, 2024 at 3:03 AM
it's big, and it's a review of 601 papers on the topic - but here's an update on Neuroinflammation in Alzheimer's Disease
www.nature.com/articles/s41...
led by Michael Heneka, published in @natrevimmunol.bsky.social today
(MANY more authors listed and linked below)
www.nature.com/articles/s41...
led by Michael Heneka, published in @natrevimmunol.bsky.social today
(MANY more authors listed and linked below)
Reposted by Dilara 🍁
Implementation and validation of single-cell genomics experiments in neuroscience - a consensus paper.
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Implementation and validation of single-cell genomics experiments in neuroscience - Nature Neuroscience
Single-cell or single-nucleus RNA-sequencing experiments form a basis for biological insights about cell types and states, but they require orthogonal experiments to confirm the functional relevance o...
www.nature.com
December 6, 2024 at 6:38 PM
Implementation and validation of single-cell genomics experiments in neuroscience - a consensus paper.
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Reposted by Dilara 🍁
Using Glittr.org to find, compare and re-use online materials for training and education https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0308729 🧬🖥️🧪
12 nextflow tutorials, 267(!) for #Rstats, 104 for Python, long tail for Docker, imaging, RNA/ATAC/etc-seq, more.
12 nextflow tutorials, 267(!) for #Rstats, 104 for Python, long tail for Docker, imaging, RNA/ATAC/etc-seq, more.
December 6, 2024 at 9:00 PM
Using Glittr.org to find, compare and re-use online materials for training and education https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0308729 🧬🖥️🧪
12 nextflow tutorials, 267(!) for #Rstats, 104 for Python, long tail for Docker, imaging, RNA/ATAC/etc-seq, more.
12 nextflow tutorials, 267(!) for #Rstats, 104 for Python, long tail for Docker, imaging, RNA/ATAC/etc-seq, more.
Reposted by Dilara 🍁
Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨
We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research!
Read more: bmcgenomics.biomedcentral.com/articles/10....
1/8
High content of nuclei-free low-quality cells in reference single-cell atlases: a call for more stringent quality control using nuclear fraction - BMC Genomics
The advent of droplet-based single-cell RNA-sequencing (scRNA-seq) has dramatically increased data throughput, enabling the release of a diverse array of tissue cell atlases to the public. However, we...
bmcgenomics.biomedcentral.com
December 3, 2024 at 8:38 AM
Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨
We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research!
Read more: bmcgenomics.biomedcentral.com/articles/10....
1/8
Reposted by Dilara 🍁
The December issue of Nature Neuroscience is now live, featuring our Focus on Single-Cell Genomics! We hope that these consensus reviews from experts in the field will serve as a useful guide for neuroscientists regarding best practices for these approaches.
www.nature.com/neuro/volume...
www.nature.com/neuro/volume...
Nature Neuroscience - Focus on single-cell genomics in neuroscience
Single-cell and single-nucleus genomics pave the way for a comprehensive understanding of the nervous system and its diverse cell populations. Realizing this...
www.nature.com
December 3, 2024 at 7:49 PM
The December issue of Nature Neuroscience is now live, featuring our Focus on Single-Cell Genomics! We hope that these consensus reviews from experts in the field will serve as a useful guide for neuroscientists regarding best practices for these approaches.
www.nature.com/neuro/volume...
www.nature.com/neuro/volume...