Mahsa Dadar
@dadarmahsa.bsky.social
Assistant Professor, Douglas Cerebral Imaging Centre, McGill University
vandalab.github.io
Neuroimaging, Alzheimer's disease, Cerebrovascular disease, Neurodegeneration, WMH
vandalab.github.io
Neuroimaging, Alzheimer's disease, Cerebrovascular disease, Neurodegeneration, WMH
Reposted by Mahsa Dadar
Physical activity as a modifiable risk factor in preclinical Alzheimer’s disease www.nature.com/articles/s41... via @natmed.nature.com
#Alzheimers #dementia #publichealth #exercise #fitness #geriatrics #GeriSky
#Alzheimers #dementia #publichealth #exercise #fitness #geriatrics #GeriSky
Physical activity as a modifiable risk factor in preclinical Alzheimer’s disease - Nature Medicine
In cognitively normal older adults at risk for Alzheimer’s dementia, physical inactivity was associated with faster tau protein buildup and cognitive decline.
www.nature.com
November 4, 2025 at 1:37 AM
Physical activity as a modifiable risk factor in preclinical Alzheimer’s disease www.nature.com/articles/s41... via @natmed.nature.com
#Alzheimers #dementia #publichealth #exercise #fitness #geriatrics #GeriSky
#Alzheimers #dementia #publichealth #exercise #fitness #geriatrics #GeriSky
We are excited to launch The Data Quartet Challenge, recognizing student contributions to projects that integrate data from at least 2 of 4 FRQ supported Quebec Alzheimer’s and Aging cohorts (PREVENT-AD, CIMA-Q, NuAge, TRIAD), with 3 prizes of 5000$ tinyurl.com/3dy899xn
The Data Quartet Challenge.pdf
tinyurl.com
September 2, 2025 at 9:54 PM
We are excited to launch The Data Quartet Challenge, recognizing student contributions to projects that integrate data from at least 2 of 4 FRQ supported Quebec Alzheimer’s and Aging cohorts (PREVENT-AD, CIMA-Q, NuAge, TRIAD), with 3 prizes of 5000$ tinyurl.com/3dy899xn
Reposted by Mahsa Dadar
Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan | doi.org/10.1371/jour...
How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates @plosbiology.org ⤵️
How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates @plosbiology.org ⤵️
August 8, 2025 at 2:24 PM
Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan | doi.org/10.1371/jour...
How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates @plosbiology.org ⤵️
How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates @plosbiology.org ⤵️
Reposted by Mahsa Dadar
Integrating and interpreting brain maps | doi.org/10.1016/j.ti...
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
August 4, 2025 at 2:27 PM
Integrating and interpreting brain maps | doi.org/10.1016/j.ti...
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
Reposted by Mahsa Dadar
Hey #AAIC25 !
Today I'll be sharing our research on the mediating effect of WMH on spontaneous brain activity during aging! 🧠
Join me on poster 430!
@ameliemetz.bsky.social @dadarmahsa.bsky.social @yasharneuro.bsky.social @roqamoqa.bsky.social
Today I'll be sharing our research on the mediating effect of WMH on spontaneous brain activity during aging! 🧠
Join me on poster 430!
@ameliemetz.bsky.social @dadarmahsa.bsky.social @yasharneuro.bsky.social @roqamoqa.bsky.social
July 28, 2025 at 2:11 PM
Hey #AAIC25 !
Today I'll be sharing our research on the mediating effect of WMH on spontaneous brain activity during aging! 🧠
Join me on poster 430!
@ameliemetz.bsky.social @dadarmahsa.bsky.social @yasharneuro.bsky.social @roqamoqa.bsky.social
Today I'll be sharing our research on the mediating effect of WMH on spontaneous brain activity during aging! 🧠
Join me on poster 430!
@ameliemetz.bsky.social @dadarmahsa.bsky.social @yasharneuro.bsky.social @roqamoqa.bsky.social
Reposted by Mahsa Dadar
🧾 Poster #487
Data-Driven Characterization of Heterogeneous Brain Atrophy and White Matter Hyperintensity Progression in FTD (Amelie Metz @ameliemetz.bsky.social )
Tuesday, July 29
Data-Driven Characterization of Heterogeneous Brain Atrophy and White Matter Hyperintensity Progression in FTD (Amelie Metz @ameliemetz.bsky.social )
Tuesday, July 29
July 22, 2025 at 10:35 PM
🧾 Poster #487
Data-Driven Characterization of Heterogeneous Brain Atrophy and White Matter Hyperintensity Progression in FTD (Amelie Metz @ameliemetz.bsky.social )
Tuesday, July 29
Data-Driven Characterization of Heterogeneous Brain Atrophy and White Matter Hyperintensity Progression in FTD (Amelie Metz @ameliemetz.bsky.social )
Tuesday, July 29
Reposted by Mahsa Dadar
Honoured to have been awarded the Vanier Scholarship — pretty psyched about it. Big thanks to everyone who’s helped me get here!
Twenty-three #McGill doctoral & postdoctoral researchers have earned Vanier Canada Graduate Scholarships and Banting Postdoctoral Fellowships, recognizing excellence, leadership & research potential.
🔗 https://mcgill.ca/x/ist
🔗 https://mcgill.ca/x/ist
July 24, 2025 at 12:21 AM
Honoured to have been awarded the Vanier Scholarship — pretty psyched about it. Big thanks to everyone who’s helped me get here!
Reposted by Mahsa Dadar
Really excited to share this new preprint on the dynamics of alpha-synuclein spreading by Dr. Stephanie Tullo in our group. This was a long term labour of love spanning the pandemic, experimental work, and in silico modelling
www.biorxiv.org/content/10.1...
See more below ⬇️
www.biorxiv.org/content/10.1...
See more below ⬇️
In vivo and in silico alpha-synuclein propagation dynamics: The role of genotype, epicentre, and connectivity
Synucleinopathies, like Parkinson's disease (PD) are characterized by progressive accumulation and spread of misfolded alpha-synuclein (aSyn) throughout the brain. To improve understanding of disease ...
www.biorxiv.org
July 22, 2025 at 6:00 PM
Really excited to share this new preprint on the dynamics of alpha-synuclein spreading by Dr. Stephanie Tullo in our group. This was a long term labour of love spanning the pandemic, experimental work, and in silico modelling
www.biorxiv.org/content/10.1...
See more below ⬇️
www.biorxiv.org/content/10.1...
See more below ⬇️
Reposted by Mahsa Dadar
The REC Steering Committee is excited to host multiple opportunities for early career researchers across the #NIAfundedADRC Program to gather at #AAIC2025!
RSVP to connect w/other scholars and leaders from #NIA, #NINDS, and the ADRC Program: uwashington.qualtrics.com/jfe/form/SV_...
RSVP to connect w/other scholars and leaders from #NIA, #NINDS, and the ADRC Program: uwashington.qualtrics.com/jfe/form/SV_...
July 10, 2025 at 10:55 PM
The REC Steering Committee is excited to host multiple opportunities for early career researchers across the #NIAfundedADRC Program to gather at #AAIC2025!
RSVP to connect w/other scholars and leaders from #NIA, #NINDS, and the ADRC Program: uwashington.qualtrics.com/jfe/form/SV_...
RSVP to connect w/other scholars and leaders from #NIA, #NINDS, and the ADRC Program: uwashington.qualtrics.com/jfe/form/SV_...
Reposted by Mahsa Dadar
In @ohbmossig.bsky.social's first Open Datasets Special Issue paper, Wearn et al. introduce the OHBM Time Machine, a freely accessible archive of Annual Meeting content on YouTube: doi.org/10.52294/001...
@alfiewearn.bsky.social @sitek.bsky.social @sofievalk.bsky.social @stephforkel.bsky.social
@alfiewearn.bsky.social @sitek.bsky.social @sofievalk.bsky.social @stephforkel.bsky.social
June 27, 2025 at 7:23 AM
In @ohbmossig.bsky.social's first Open Datasets Special Issue paper, Wearn et al. introduce the OHBM Time Machine, a freely accessible archive of Annual Meeting content on YouTube: doi.org/10.52294/001...
@alfiewearn.bsky.social @sitek.bsky.social @sofievalk.bsky.social @stephforkel.bsky.social
@alfiewearn.bsky.social @sitek.bsky.social @sofievalk.bsky.social @stephforkel.bsky.social
Reposted by Mahsa Dadar
wonderful opportunity for junior faculty
Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages.
ki.se/en/about-ki/...
ki.se/en/about-ki/...
Call for 20 Assistant Professor positions
Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...
ki.se
June 28, 2025 at 12:37 AM
wonderful opportunity for junior faculty
Reposted by Mahsa Dadar
🚨New preprint 🚨
TL;DR Supporting cerebrovascular and mental health, along with staying cognitively engaged, may help preserve brain function and delay cognitive decline and dementia.
@dzne.science
TL;DR Supporting cerebrovascular and mental health, along with staying cognitively engaged, may help preserve brain function and delay cognitive decline and dementia.
@dzne.science
Linking latent trajectories of ageing-related atrophy, white matter hyperintensities, and cognitive ageing over four years: Insights into brain maintenance https://www.medrxiv.org/content/10.1101/2025.06.16.25329648v1
June 17, 2025 at 9:26 PM
🚨New preprint 🚨
TL;DR Supporting cerebrovascular and mental health, along with staying cognitively engaged, may help preserve brain function and delay cognitive decline and dementia.
@dzne.science
TL;DR Supporting cerebrovascular and mental health, along with staying cognitively engaged, may help preserve brain function and delay cognitive decline and dementia.
@dzne.science
Reposted by Mahsa Dadar
After 3 years of "just one more analysis", our work on WMH pathophysiology is finally out!
Building on previous post-mortem findings of non-vascular WMHs, we identified a specific signature of neurodegenerative WMHs in vivo using microstructural MRI and normative modeling
doi.org/10.1101/2025...
Building on previous post-mortem findings of non-vascular WMHs, we identified a specific signature of neurodegenerative WMHs in vivo using microstructural MRI and normative modeling
doi.org/10.1101/2025...
Characterizing spatiotemporal white matter hyperintensity pathophysiology in vivo to disentangle vascular and neurodegenerative contributions
White matter hyperintensities (WMHs) are neuroimaging markers widely interpreted as caused by cerebral small vessel disease, yet emerging evidence suggests that a subset may have a neurodegenerative e...
doi.org
June 12, 2025 at 5:49 PM
After 3 years of "just one more analysis", our work on WMH pathophysiology is finally out!
Building on previous post-mortem findings of non-vascular WMHs, we identified a specific signature of neurodegenerative WMHs in vivo using microstructural MRI and normative modeling
doi.org/10.1101/2025...
Building on previous post-mortem findings of non-vascular WMHs, we identified a specific signature of neurodegenerative WMHs in vivo using microstructural MRI and normative modeling
doi.org/10.1101/2025...
Reposted by Mahsa Dadar
Sex Differences in Vulnerability to Tau Pathology: Impact on Cognitive Decline https://www.medrxiv.org/content/10.1101/2025.05.25.25328324v1
May 27, 2025 at 2:26 AM
Sex Differences in Vulnerability to Tau Pathology: Impact on Cognitive Decline https://www.medrxiv.org/content/10.1101/2025.05.25.25328324v1
Reposted by Mahsa Dadar
Gray matter microstructure from in-vivo diffusion MRI reflects post-mortem neuropathology severity and clinical progression of Alzheimer's disease https://www.medrxiv.org/content/10.1101/2025.05.30.25328630v1
June 4, 2025 at 9:11 PM
Gray matter microstructure from in-vivo diffusion MRI reflects post-mortem neuropathology severity and clinical progression of Alzheimer's disease https://www.medrxiv.org/content/10.1101/2025.05.30.25328630v1
Reposted by Mahsa Dadar
Vascular risk factors mediate the relationship between education and white matter hyperintensities https://www.medrxiv.org/content/10.1101/2025.06.03.25328899v1
June 5, 2025 at 1:26 AM
Vascular risk factors mediate the relationship between education and white matter hyperintensities https://www.medrxiv.org/content/10.1101/2025.06.03.25328899v1
Reposted by Mahsa Dadar
Happy to see my first first-author paper in Imaging Neuroscience (along with @fmrib-karla.bsky.social and @nichols.bsky.social):
Characterising ongoing brain aging and baseline effects from cross-sectional data
doi.org/10.1162/IMAG...
Characterising ongoing brain aging and baseline effects from cross-sectional data
doi.org/10.1162/IMAG...
May 29, 2025 at 5:16 AM
Happy to see my first first-author paper in Imaging Neuroscience (along with @fmrib-karla.bsky.social and @nichols.bsky.social):
Characterising ongoing brain aging and baseline effects from cross-sectional data
doi.org/10.1162/IMAG...
Characterising ongoing brain aging and baseline effects from cross-sectional data
doi.org/10.1162/IMAG...
Reposted by Mahsa Dadar
Parkinson's disease links to ultra-processed foods and pesticides
www.nytimes.com/2025/05/07/w...
www.nytimes.com/2025/05/07/w...
jamanetwork.com/journals/jam...
www.nytimes.com/2025/05/07/w...
www.nytimes.com/2025/05/07/w...
jamanetwork.com/journals/jam...
May 9, 2025 at 4:49 PM
Parkinson's disease links to ultra-processed foods and pesticides
www.nytimes.com/2025/05/07/w...
www.nytimes.com/2025/05/07/w...
jamanetwork.com/journals/jam...
www.nytimes.com/2025/05/07/w...
www.nytimes.com/2025/05/07/w...
jamanetwork.com/journals/jam...
Reposted by Mahsa Dadar
Chemical additives in plastics (phthalates) and cardiovascular mortality
www.thelancet.com/journals/ebi...
www.thelancet.com/journals/ebi...
April 29, 2025 at 1:35 PM
Chemical additives in plastics (phthalates) and cardiovascular mortality
www.thelancet.com/journals/ebi...
www.thelancet.com/journals/ebi...
Reposted by Mahsa Dadar
Our Department of Global and Public Health within McGill University School of Population and Global Health is recruiting an Assistant Professor (Tenure Track).
Apply now! 👇
mcgill.wd3.myworkdayjobs.com/en-US/McGill...
Apply now! 👇
mcgill.wd3.myworkdayjobs.com/en-US/McGill...
April 29, 2025 at 1:19 AM
Our Department of Global and Public Health within McGill University School of Population and Global Health is recruiting an Assistant Professor (Tenure Track).
Apply now! 👇
mcgill.wd3.myworkdayjobs.com/en-US/McGill...
Apply now! 👇
mcgill.wd3.myworkdayjobs.com/en-US/McGill...
Reposted by Mahsa Dadar
Reducing the risk of all-cause dementia with intensive blood pressure control, the results of a cluster randomized trial in~34,000 participants. @naturemedicine.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Blood pressure reduction and all-cause dementia in people with uncontrolled hypertension: an open-label, blinded-endpoint, cluster-randomized trial - Nature Medicine
In the CRHCP-3 cluster-randomized trial, blood pressure reduction lowered the risk of all-cause dementia by 15% in 33,995 individuals with hypertension.
www.nature.com
April 21, 2025 at 3:58 PM
Reducing the risk of all-cause dementia with intensive blood pressure control, the results of a cluster randomized trial in~34,000 participants. @naturemedicine.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Mahsa Dadar
Hey #ADPD2025 , I'm happy to present our work on characterizing brain atrophy and cerebrovascular pathology in Frontotemporal Dementia subtypes!
Tomorrow, April 5, 9:40am, Hall F2, session: Mechanisms and Clinical Trials in FTD, ALS, and Neurodegeneration 02
Tomorrow, April 5, 9:40am, Hall F2, session: Mechanisms and Clinical Trials in FTD, ALS, and Neurodegeneration 02
April 4, 2025 at 10:25 AM
Hey #ADPD2025 , I'm happy to present our work on characterizing brain atrophy and cerebrovascular pathology in Frontotemporal Dementia subtypes!
Tomorrow, April 5, 9:40am, Hall F2, session: Mechanisms and Clinical Trials in FTD, ALS, and Neurodegeneration 02
Tomorrow, April 5, 9:40am, Hall F2, session: Mechanisms and Clinical Trials in FTD, ALS, and Neurodegeneration 02
Reposted by Mahsa Dadar
There's a stream of excellent papers in @apertureohbm.bsky.social being published!
Check them out: apertureneuro.org
Submit your own
+code
+data
+open science
+imaging studies+
Quick turnaround, a devoted ed board, and lowest APC around.
And you'll support @ohbmofficial.bsky.social
share pls!
Check them out: apertureneuro.org
Submit your own
+code
+data
+open science
+imaging studies+
Quick turnaround, a devoted ed board, and lowest APC around.
And you'll support @ohbmofficial.bsky.social
share pls!
March 22, 2025 at 2:28 PM
There's a stream of excellent papers in @apertureohbm.bsky.social being published!
Check them out: apertureneuro.org
Submit your own
+code
+data
+open science
+imaging studies+
Quick turnaround, a devoted ed board, and lowest APC around.
And you'll support @ohbmofficial.bsky.social
share pls!
Check them out: apertureneuro.org
Submit your own
+code
+data
+open science
+imaging studies+
Quick turnaround, a devoted ed board, and lowest APC around.
And you'll support @ohbmofficial.bsky.social
share pls!
Reposted by Mahsa Dadar
Metz et al. report that a study combining MRI brain atrophy and clinical data using machine learning achieved 89% accuracy in classifying frontotemporal dementia subtypes. Please read at:https://buff.ly/uGmX2fg @DadarMahsa @YasharZeighami @sylv_villeneuve @sducharme66
March 22, 2025 at 9:00 AM
Metz et al. report that a study combining MRI brain atrophy and clinical data using machine learning achieved 89% accuracy in classifying frontotemporal dementia subtypes. Please read at:https://buff.ly/uGmX2fg @DadarMahsa @YasharZeighami @sylv_villeneuve @sducharme66
Reposted by Mahsa Dadar
Metz et al. report that a study combining MRI brain atrophy and clinical data using machine learning achieved 89% accuracy in classifying frontotemporal dementia subtypes. Please read at:https://buff.ly/uGmX2fg @DadarMahsa @YasharZeighami @sylv_villeneuve @sducharme66
March 22, 2025 at 1:43 PM