Colleen E. Clancy PhD
@clancyatheart.bsky.social
Colleen E. Clancy, Ph.D.
Editor-in-Chief: The Journal of Precision Medicine, Professor of Physiology and Director of Precision Medicine at UC Davis
Editor-in-Chief: The Journal of Precision Medicine, Professor of Physiology and Director of Precision Medicine at UC Davis
Reposted by Colleen E. Clancy PhD
We're incredibly excited to announce that Dr. Theanne Griffith @doctheagrif.bsky.social of #PMB Griffith Lab has been promoted to Associate Professor with tenure, effective July 1, 2026! Congratulations, Theanne, on this well-earned achievement! 🎉🌟
Her lab research: www.thegriffithresearchgroup.com
Her lab research: www.thegriffithresearchgroup.com
January 23, 2026 at 5:48 PM
We're incredibly excited to announce that Dr. Theanne Griffith @doctheagrif.bsky.social of #PMB Griffith Lab has been promoted to Associate Professor with tenure, effective July 1, 2026! Congratulations, Theanne, on this well-earned achievement! 🎉🌟
Her lab research: www.thegriffithresearchgroup.com
Her lab research: www.thegriffithresearchgroup.com
Reposted by Colleen E. Clancy PhD
Day2️⃣ of the NRMP 5th Anniversary Highlights 🧁
@clancyatheart.bsky.social and @masi-lab.bsky.social discuss the emerging role of digital twins, combined with AI, for biomedical research that can inform preclinical decisions.
www.nature.com/articles/s43...
@clancyatheart.bsky.social and @masi-lab.bsky.social discuss the emerging role of digital twins, combined with AI, for biomedical research that can inform preclinical decisions.
www.nature.com/articles/s43...
Client Challenge
www.nature.com
January 12, 2026 at 4:09 PM
Day2️⃣ of the NRMP 5th Anniversary Highlights 🧁
@clancyatheart.bsky.social and @masi-lab.bsky.social discuss the emerging role of digital twins, combined with AI, for biomedical research that can inform preclinical decisions.
www.nature.com/articles/s43...
@clancyatheart.bsky.social and @masi-lab.bsky.social discuss the emerging role of digital twins, combined with AI, for biomedical research that can inform preclinical decisions.
www.nature.com/articles/s43...
Reposted by Colleen E. Clancy PhD
A new piece in @natrevmethodsprimers.nature.com from #PMB faculty member @clancyatheart.bsky.social "Towards credible digital twins for basic and preclinical research" www.nature.com/articles/s43...
Client Challenge
www.nature.com
January 8, 2026 at 11:22 PM
A new piece in @natrevmethodsprimers.nature.com from #PMB faculty member @clancyatheart.bsky.social "Towards credible digital twins for basic and preclinical research" www.nature.com/articles/s43...
A new internationally author group with a deeply relevant publication highlighting key issues and challenges in precision medicine: jprecisionmedicine.org/article/S305... @jprecmed.bsky.social @jphysiol.bsky.social @physoc.bsky.social
January 3, 2026 at 2:50 AM
A new internationally author group with a deeply relevant publication highlighting key issues and challenges in precision medicine: jprecisionmedicine.org/article/S305... @jprecmed.bsky.social @jphysiol.bsky.social @physoc.bsky.social
Reposted by Colleen E. Clancy PhD
Just in time for the Holidays, our latest paper on how #amyloidbeta regulates the spatiotemporal properties of vascular L-type channels - implications for vascular function.
Great work by Jade and team! @ucdavis.bsky.social, @ucdavishealth.bsky.social
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Great work by Jade and team! @ucdavis.bsky.social, @ucdavishealth.bsky.social
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Amyloid β alters vascular CaV1.2 channel spatiotemporal properties
Abstract figure legend Amyloid-β1-42 (Aβ1-42) triggers a male-specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway invol...
physoc.onlinelibrary.wiley.com
December 20, 2025 at 1:17 PM
Just in time for the Holidays, our latest paper on how #amyloidbeta regulates the spatiotemporal properties of vascular L-type channels - implications for vascular function.
Great work by Jade and team! @ucdavis.bsky.social, @ucdavishealth.bsky.social
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Great work by Jade and team! @ucdavis.bsky.social, @ucdavishealth.bsky.social
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by Colleen E. Clancy PhD
In @jgp.org, Jenna Lin and Baron Chanda compare different gating models to account for the diverse gating phenotypes observed across the cyclic nucleotide-binding domain (CNBD) family, including those arising from targeted mutations and chimeragenesis. rupress.org/jgp/article/...
#IonChannels
#IonChannels
December 11, 2025 at 6:33 PM
In @jgp.org, Jenna Lin and Baron Chanda compare different gating models to account for the diverse gating phenotypes observed across the cyclic nucleotide-binding domain (CNBD) family, including those arising from targeted mutations and chimeragenesis. rupress.org/jgp/article/...
#IonChannels
#IonChannels
Reposted by Colleen E. Clancy PhD
Great way to start the final month of the year with the publication of this collaborative work on how dopamine regulates L-type channels in #neurons.
www.science.org/doi/10.1126/...
And we got the cover!!! @ucdavis.bsky.social, @ucdavishealth.bsky.social
www.science.org/doi/10.1126/...
And we got the cover!!! @ucdavis.bsky.social, @ucdavishealth.bsky.social
Stimulation of Ca2+ channel CaV1.2 activity by dopamine signaling augments spatial working memory
Dopamine-induced phosphorylation of an L-type Ca2+ channel supports working memory in mice.
www.science.org
December 9, 2025 at 11:32 PM
Great way to start the final month of the year with the publication of this collaborative work on how dopamine regulates L-type channels in #neurons.
www.science.org/doi/10.1126/...
And we got the cover!!! @ucdavis.bsky.social, @ucdavishealth.bsky.social
www.science.org/doi/10.1126/...
And we got the cover!!! @ucdavis.bsky.social, @ucdavishealth.bsky.social
Congratulations!!!!!
December 10, 2025 at 12:46 AM
Congratulations!!!!!
We are anticipating a truly exceptional collection of studies based on current commitments! Please send us your study on NAMs - we would love to have a chance to review it!
Colleagues, we are excited to receive your papers on New Approach Methodologies! Reach out to me if you have a presubmission question!
📣 CALL FOR PAPERS📣
Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎
Submit by 28 February 2026 ⏰
🔗 For topics and more information:
www.sciencedirect.com/special-issu...
Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎
Submit by 28 February 2026 ⏰
🔗 For topics and more information:
www.sciencedirect.com/special-issu...
December 10, 2025 at 12:42 AM
We are anticipating a truly exceptional collection of studies based on current commitments! Please send us your study on NAMs - we would love to have a chance to review it!
Reposted by Colleen E. Clancy PhD
📣CALL FOR PAPERS📣
For our "Contemporary antioxidant interventions: transforming the study of redox #biology in health and disease" #SpecialIssue! This special issue will provide insights into the #redox mechanisms underpinning health and disease!
🎓 buff.ly/LGKQ90r
For our "Contemporary antioxidant interventions: transforming the study of redox #biology in health and disease" #SpecialIssue! This special issue will provide insights into the #redox mechanisms underpinning health and disease!
🎓 buff.ly/LGKQ90r
December 3, 2025 at 5:02 PM
📣CALL FOR PAPERS📣
For our "Contemporary antioxidant interventions: transforming the study of redox #biology in health and disease" #SpecialIssue! This special issue will provide insights into the #redox mechanisms underpinning health and disease!
🎓 buff.ly/LGKQ90r
For our "Contemporary antioxidant interventions: transforming the study of redox #biology in health and disease" #SpecialIssue! This special issue will provide insights into the #redox mechanisms underpinning health and disease!
🎓 buff.ly/LGKQ90r
Colleagues, we are excited to receive your papers on New Approach Methodologies! Reach out to me if you have a presubmission question!
📣 CALL FOR PAPERS📣
Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎
Submit by 28 February 2026 ⏰
🔗 For topics and more information:
www.sciencedirect.com/special-issu...
Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎
Submit by 28 February 2026 ⏰
🔗 For topics and more information:
www.sciencedirect.com/special-issu...
October 20, 2025 at 7:40 PM
Colleagues, we are excited to receive your papers on New Approach Methodologies! Reach out to me if you have a presubmission question!
Reposted by Colleen E. Clancy PhD
📣 CALL FOR PAPERS📣
Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎
Submit by 28 February 2026 ⏰
🔗 For topics and more information:
www.sciencedirect.com/special-issu...
Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎
Submit by 28 February 2026 ⏰
🔗 For topics and more information:
www.sciencedirect.com/special-issu...
October 6, 2025 at 2:42 PM
📣 CALL FOR PAPERS📣
Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎
Submit by 28 February 2026 ⏰
🔗 For topics and more information:
www.sciencedirect.com/special-issu...
Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎
Submit by 28 February 2026 ⏰
🔗 For topics and more information:
www.sciencedirect.com/special-issu...
Reposted by Colleen E. Clancy PhD
Jehad Feras AlSamhori of The University of Jordan et al. examine the role of #ChatGPT in improving orthopedic patient education in low-resource settings across various #orthopedic specialties ✍️ 🥼
🔗 📜 Read the #Review here: www.jprecisionmedicine.org/article/S305...
🔗 📜 Read the #Review here: www.jprecisionmedicine.org/article/S305...
October 13, 2025 at 12:00 PM
Jehad Feras AlSamhori of The University of Jordan et al. examine the role of #ChatGPT in improving orthopedic patient education in low-resource settings across various #orthopedic specialties ✍️ 🥼
🔗 📜 Read the #Review here: www.jprecisionmedicine.org/article/S305...
🔗 📜 Read the #Review here: www.jprecisionmedicine.org/article/S305...
Reposted by Colleen E. Clancy PhD
In this recent #Review, Umama Shahid of Monash University Malaysia discusses the mechanistic insights, multi-omics integration, and translational horizons of #microbiome-guided precision medicine ✍️ 💉
🔗 Read the article here:
www.jprecisionmedicine.org/article/S305...
🔗 Read the article here:
www.jprecisionmedicine.org/article/S305...
October 14, 2025 at 2:02 PM
In this recent #Review, Umama Shahid of Monash University Malaysia discusses the mechanistic insights, multi-omics integration, and translational horizons of #microbiome-guided precision medicine ✍️ 💉
🔗 Read the article here:
www.jprecisionmedicine.org/article/S305...
🔗 Read the article here:
www.jprecisionmedicine.org/article/S305...
Reposted by Colleen E. Clancy PhD
🚨CALL FOR PAPERS🚨
For our "Integrative physiological considerations of the human vasculature system" #SpecialIssue, which will showcase further insights into vascular haemodynamics and multi-organ diseases, as well as the technology used to monitor and treat cardiovascular disease
🔗 buff.ly/HN7wlPr
For our "Integrative physiological considerations of the human vasculature system" #SpecialIssue, which will showcase further insights into vascular haemodynamics and multi-organ diseases, as well as the technology used to monitor and treat cardiovascular disease
🔗 buff.ly/HN7wlPr
September 17, 2025 at 4:10 PM
🚨CALL FOR PAPERS🚨
For our "Integrative physiological considerations of the human vasculature system" #SpecialIssue, which will showcase further insights into vascular haemodynamics and multi-organ diseases, as well as the technology used to monitor and treat cardiovascular disease
🔗 buff.ly/HN7wlPr
For our "Integrative physiological considerations of the human vasculature system" #SpecialIssue, which will showcase further insights into vascular haemodynamics and multi-organ diseases, as well as the technology used to monitor and treat cardiovascular disease
🔗 buff.ly/HN7wlPr
Reposted by Colleen E. Clancy PhD
Turning sunlight into fuel [via Uni of Basel] 🧪⚗️🪴🌞⛽🔋
"a plant-inspired molecule that can store four charges using sunlight, a key step toward artificial photosynthesis"
www.nature.com/articles/s41...
#artificial #photosynthesis #sunlight #fuel #energy #environment #friendly
"a plant-inspired molecule that can store four charges using sunlight, a key step toward artificial photosynthesis"
www.nature.com/articles/s41...
#artificial #photosynthesis #sunlight #fuel #energy #environment #friendly
Photoinduced double charge accumulation in a molecular compound - Nature Chemistry
The photoinduced accumulation of redox equivalents is a challenging requirement for artificial photosynthesis. Now a molecule has been developed in which the sequential absorption of photons results i...
www.nature.com
August 26, 2025 at 6:31 PM
Turning sunlight into fuel [via Uni of Basel] 🧪⚗️🪴🌞⛽🔋
"a plant-inspired molecule that can store four charges using sunlight, a key step toward artificial photosynthesis"
www.nature.com/articles/s41...
#artificial #photosynthesis #sunlight #fuel #energy #environment #friendly
"a plant-inspired molecule that can store four charges using sunlight, a key step toward artificial photosynthesis"
www.nature.com/articles/s41...
#artificial #photosynthesis #sunlight #fuel #energy #environment #friendly
Please join us for the upcoming NHLBI workshop on digital twins!
Please register and spread the word! www.nhlbi.nih.gov/events/2025/...
Please register and spread the word! www.nhlbi.nih.gov/events/2025/...
Digital Twins in Heart, Lung, Blood, and Sleep Research Virtual Workshop
The Digital Twins in Heart, Lung, Blood, and Sleep Research Virtual Workshop will take place virtually on September 25–26, 2025.
www.nhlbi.nih.gov
August 22, 2025 at 7:59 PM
Please join us for the upcoming NHLBI workshop on digital twins!
Please register and spread the word! www.nhlbi.nih.gov/events/2025/...
Please register and spread the word! www.nhlbi.nih.gov/events/2025/...
Reposted by Colleen E. Clancy PhD
"If the U.S. is no longer the world’s technoscientific superpower, it will almost certainly suffer for the change. America’s technology sector might lose its creativity. But science itself, in the global sense, will be fine. The deep human curiosities that drive it do not belong to any nation-state"
Every Scientific Empire Comes to an End
America’s run as the premier techno-superpower may be over.
www.theatlantic.com
August 2, 2025 at 9:48 PM
"If the U.S. is no longer the world’s technoscientific superpower, it will almost certainly suffer for the change. America’s technology sector might lose its creativity. But science itself, in the global sense, will be fine. The deep human curiosities that drive it do not belong to any nation-state"
Reposted by Colleen E. Clancy PhD
Mind the midpoints: Rethinking variability in cardiac INa. Commentary from @clancyatheart.bsky.social @ucd-physiology.bsky.social highlighting the new study from @michaelclerx.com and colleagues (rupress.org/jgp/article/...): rupress.org/jgp/article/...
July 23, 2025 at 6:15 PM
Mind the midpoints: Rethinking variability in cardiac INa. Commentary from @clancyatheart.bsky.social @ucd-physiology.bsky.social highlighting the new study from @michaelclerx.com and colleagues (rupress.org/jgp/article/...): rupress.org/jgp/article/...
Reposted by Colleen E. Clancy PhD
We traveled to DC to talk to Congressional Staffers about the impact of NIH and NIBIB funding. It enables us to develop synthetic biology tools to advance cell & genetic medicines for patients in need. REPOST to deliver the message that SCIENCE saves lives & makes America GREAT!
July 21, 2025 at 12:16 PM
We traveled to DC to talk to Congressional Staffers about the impact of NIH and NIBIB funding. It enables us to develop synthetic biology tools to advance cell & genetic medicines for patients in need. REPOST to deliver the message that SCIENCE saves lives & makes America GREAT!
Reposted by Colleen E. Clancy PhD
Hope you like it!
Thanks to the very helpful reviewers and editor.
And an extra special thank you to @clancyatheart.bsky.social who wrote a very thoughtful commentary here: doi.org/10.1085/jgp....
Thanks to the very helpful reviewers and editor.
And an extra special thank you to @clancyatheart.bsky.social who wrote a very thoughtful commentary here: doi.org/10.1085/jgp....
Mind the midpoints: Rethinking variability in cardiac INa | Journal of General Physiology | Rockefeller University Press
The comprehensive meta-analysis from Clerx and coauthors challenges long-standing assumptions about data interpretation, data comparison, and electrophysio
doi.org
July 16, 2025 at 4:55 PM
Hope you like it!
Thanks to the very helpful reviewers and editor.
And an extra special thank you to @clancyatheart.bsky.social who wrote a very thoughtful commentary here: doi.org/10.1085/jgp....
Thanks to the very helpful reviewers and editor.
And an extra special thank you to @clancyatheart.bsky.social who wrote a very thoughtful commentary here: doi.org/10.1085/jgp....
Reposted by Colleen E. Clancy PhD
@clancyatheart.bsky.social highlights the comprehensive meta-analysis in @jgp.org from Clerx et al. (rupress.org/jgp/article/... ) that challenges long-standing assumptions about data interpretation, data comparison, and electrophysiological data used to develop models. rupress.org/jgp/article/...
July 16, 2025 at 7:30 PM
@clancyatheart.bsky.social highlights the comprehensive meta-analysis in @jgp.org from Clerx et al. (rupress.org/jgp/article/... ) that challenges long-standing assumptions about data interpretation, data comparison, and electrophysiological data used to develop models. rupress.org/jgp/article/...
So excited to share our study just published in eLife, “Harnessing AlphaFold to reveal hERG channel conformational state secrets” doi.org/10.7554/eLif...
Harnessing AlphaFold to reveal hERG channel conformational state secrets
Customized AlphaFold-based modeling of distinct functional states of the hERG channel, a major drug anti-target, significantly improves drug affinity predictions, enhancing cardiac safety screening fo...
doi.org
July 14, 2025 at 11:21 PM
So excited to share our study just published in eLife, “Harnessing AlphaFold to reveal hERG channel conformational state secrets” doi.org/10.7554/eLif...
So thrilling to share this game changing study from Dr. Patrick Ott group at Dana Farber. Dr. Ott is one of our esteemed senior editors at the Journal of Precision Medicine: Health and Disease! www.sciencedirect.com/science/arti...
A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma
Personalized neoantigen-targeting vaccines have demonstrated great promise; however, improved immunogenicity is still needed. Since antigen availabili…
www.sciencedirect.com
July 10, 2025 at 4:50 PM
So thrilling to share this game changing study from Dr. Patrick Ott group at Dana Farber. Dr. Ott is one of our esteemed senior editors at the Journal of Precision Medicine: Health and Disease! www.sciencedirect.com/science/arti...
Reposted by Colleen E. Clancy PhD
Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
July 7, 2025 at 2:05 PM
Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).
Please apply and/or repost!
jobs.unige.ch/www/wd_porta...