Claire Wyart
@clairewyart.bsky.social
Team Leader @Paris Brain Institute &
Inserm Director. Fascinated by navigation, movement and brain body interactions. Passion for interdisciplinary training. Knows biodiversity and climate demand changing my game... more on wyartlab.org
Inserm Director. Fascinated by navigation, movement and brain body interactions. Passion for interdisciplinary training. Knows biodiversity and climate demand changing my game... more on wyartlab.org
Pinned
Claire Wyart
@clairewyart.bsky.social
· Aug 20
Hey #motorcontrol researchers! @jul-bouvier.bsky.social, LeMouel & I organize *Searching for principles in Motor Control* Paris Sept 23-24, 25 @sorbonne-universite.fr @institutducerveau.bsky.social @neuropsi.bsky.social: Submit Abstract for Posters by Aug 31! motorconference.sciencesconf.org?lang=en
Motor Folks: a nice opportunity to present your work & get feedback! BTW registration to the Conference "Searching Principles in Motor Control" on Sept 23-24, 25 is free but mandatory, please sign up and present your work to the French community ! motorconference.sciencesconf.org?lang=en
August 26, 2025 at 1:25 PM
Motor Folks: a nice opportunity to present your work & get feedback! BTW registration to the Conference "Searching Principles in Motor Control" on Sept 23-24, 25 is free but mandatory, please sign up and present your work to the French community ! motorconference.sciencesconf.org?lang=en
Hey #motorcontrol researchers! @jul-bouvier.bsky.social, LeMouel & I organize *Searching for principles in Motor Control* Paris Sept 23-24, 25 @sorbonne-universite.fr @institutducerveau.bsky.social @neuropsi.bsky.social: Submit Abstract for Posters by Aug 31! motorconference.sciencesconf.org?lang=en
August 20, 2025 at 12:56 PM
Hey #motorcontrol researchers! @jul-bouvier.bsky.social, LeMouel & I organize *Searching for principles in Motor Control* Paris Sept 23-24, 25 @sorbonne-universite.fr @institutducerveau.bsky.social @neuropsi.bsky.social: Submit Abstract for Posters by Aug 31! motorconference.sciencesconf.org?lang=en
We work on humans with @antoniocbscosta.bsky.social @marcoromanato.bsky.social @wyartlab.bsky.social predicting effects of #DBS in Parkinson's Disease patients. Yet, understanding cellular & circuit mechanisms underlying behaviour require model organisms 🎏🐭🪱🪰 & cannot be done in humans nor organoids
Dear all, PLEASE add comments on the importance of model organism research at this link:
July 12, 2025 at 12:07 PM
We work on humans with @antoniocbscosta.bsky.social @marcoromanato.bsky.social @wyartlab.bsky.social predicting effects of #DBS in Parkinson's Disease patients. Yet, understanding cellular & circuit mechanisms underlying behaviour require model organisms 🎏🐭🪱🪰 & cannot be done in humans nor organoids
Reposted by Claire Wyart
Congratulations to the 2025 George Streisinger Award Winners! And, thank you, to your contributions to the #zebrafish field! #IZFC2025
July 11, 2025 at 8:24 PM
Congratulations to the 2025 George Streisinger Award Winners! And, thank you, to your contributions to the #zebrafish field! #IZFC2025
Reposted by Claire Wyart
Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social @jasperjanssens.bsky.social and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1
July 11, 2025 at 8:59 PM
Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social @jasperjanssens.bsky.social and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1
Reposted by Claire Wyart
Chronic back pain affects most of us eventually, and ageing discs are often to blame. But cellular senescence may not be irreversible.
This Insight Article explores how platelet-derived growth factors could help revive ageing disc cells.
buff.ly/VjINkon
This Insight Article explores how platelet-derived growth factors could help revive ageing disc cells.
buff.ly/VjINkon
Senescence: Returning aging cells to productivity
Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.
buff.ly
July 11, 2025 at 10:28 PM
Chronic back pain affects most of us eventually, and ageing discs are often to blame. But cellular senescence may not be irreversible.
This Insight Article explores how platelet-derived growth factors could help revive ageing disc cells.
buff.ly/VjINkon
This Insight Article explores how platelet-derived growth factors could help revive ageing disc cells.
buff.ly/VjINkon
Reposted by Claire Wyart
Dear #izfc2025 participants, if anyone of you are interested in how transcription control defines mRNA fate and translation in zebrafish development, there are/will be several PhD and postdoctoral positions (funded by the Wellcome Trust) for this research. Please find me if interested.
July 11, 2025 at 9:28 PM
Dear #izfc2025 participants, if anyone of you are interested in how transcription control defines mRNA fate and translation in zebrafish development, there are/will be several PhD and postdoctoral positions (funded by the Wellcome Trust) for this research. Please find me if interested.
Reposted by Claire Wyart
Ferenc is great, super opportunity!
Dear #izfc2025 participants, if anyone of you are interested in how transcription control defines mRNA fate and translation in zebrafish development, there are/will be several PhD and postdoctoral positions (funded by the Wellcome Trust) for this research. Please find me if interested.
July 11, 2025 at 11:59 PM
Ferenc is great, super opportunity!
Reposted by Claire Wyart
The winners of the 2025 George Streisinger Award are the Course Directors of the Zebrafish Development and Genetics course at MBL, for their tremendous contributions to our amazing community for >25 years! #izfc2025
July 11, 2025 at 10:40 PM
The winners of the 2025 George Streisinger Award are the Course Directors of the Zebrafish Development and Genetics course at MBL, for their tremendous contributions to our amazing community for >25 years! #izfc2025
Reposted by Claire Wyart
Dear all, PLEASE add comments on the importance of model organism research at this link:
July 11, 2025 at 4:34 PM
Dear all, PLEASE add comments on the importance of model organism research at this link:
Reposted by Claire Wyart
NIH suspending or terminating grants with a very broad definition of dangerous gain of function research (which appears to include standard safe laboratory procedures)
www.science.org/content/arti...
www.science.org/content/arti...
Exclusive: NIH suspends dozens of pathogen studies over ‘gain-of-function’ concerns
Trump executive order leads to pauses on U.S.-funded research into TB, influenza, COVID-19, and other diseases, dismaying some scientists
www.science.org
July 12, 2025 at 12:14 AM
NIH suspending or terminating grants with a very broad definition of dangerous gain of function research (which appears to include standard safe laboratory procedures)
www.science.org/content/arti...
www.science.org/content/arti...
Reposted by Claire Wyart
V cool work from @ebriefer.bsky.social et al on how selection for sociability alters vocal signals (in sheep!) bit.ly/40AHKTd
1. Isolation but not feeding calls distinguish 🐑 selected for high vs low sociability
2. More selection for sociability ➡️ Less vocal individuality
#prattle 💬 #bioacoustics
1. Isolation but not feeding calls distinguish 🐑 selected for high vs low sociability
2. More selection for sociability ➡️ Less vocal individuality
#prattle 💬 #bioacoustics
July 11, 2025 at 3:51 PM
V cool work from @ebriefer.bsky.social et al on how selection for sociability alters vocal signals (in sheep!) bit.ly/40AHKTd
1. Isolation but not feeding calls distinguish 🐑 selected for high vs low sociability
2. More selection for sociability ➡️ Less vocal individuality
#prattle 💬 #bioacoustics
1. Isolation but not feeding calls distinguish 🐑 selected for high vs low sociability
2. More selection for sociability ➡️ Less vocal individuality
#prattle 💬 #bioacoustics
Reposted by Claire Wyart
Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
May 12, 2025 at 5:25 AM
Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
Reposted by Claire Wyart
It took us many years to improve idtracker.ai in both accuracy and tracking time. Here it is.
June 3, 2025 at 2:46 PM
It took us many years to improve idtracker.ai in both accuracy and tracking time. Here it is.
Reposted by Claire Wyart
Downstream @etlunsford.bsky.social mapped how the corresponding interneurons in the brainstem project onto reticulospinal neurons to select the steering command eliciting either forward or turns ... recalling the pioneering work of @daniobrain.bsky.social on optical motor response to flow! (5)
July 2, 2025 at 3:37 PM
Downstream @etlunsford.bsky.social mapped how the corresponding interneurons in the brainstem project onto reticulospinal neurons to select the steering command eliciting either forward or turns ... recalling the pioneering work of @daniobrain.bsky.social on optical motor response to flow! (5)
Reposted by Claire Wyart
The tackle this question, @etlunsford.bsky.social 🌬️ stimulated each & all neuromasts along the body & discovered a simple principle within the brainstem !! Namely, information on location & direction is encoded in an egocentric referential around the center of mass! www.biorxiv.org/content/10.1...
July 2, 2025 at 3:25 PM
The tackle this question, @etlunsford.bsky.social 🌬️ stimulated each & all neuromasts along the body & discovered a simple principle within the brainstem !! Namely, information on location & direction is encoded in an egocentric referential around the center of mass! www.biorxiv.org/content/10.1...
Reposted by Claire Wyart
Fish display mechanosensors called neuromasts covering their body from head to tail. In each neuromast, hair cells can sense changes in water flow along different directions in the anteroposterior axis, either tailward or headward. How does the brain compute the flow information across the body? (2)
July 2, 2025 at 3:19 PM
Fish display mechanosensors called neuromasts covering their body from head to tail. In each neuromast, hair cells can sense changes in water flow along different directions in the anteroposterior axis, either tailward or headward. How does the brain compute the flow information across the body? (2)
Reposted by Claire Wyart
By combining controlled mechanical stimulation & whole brain #imaging, @etlunsford.bsky.social revealed an essential principle 💡... Mechanosensory inputs from any directions along the body are encoded relative to the center of mass (COM)! Recalling #olfaction with odors encoded by pleasantness (4)
July 2, 2025 at 3:32 PM
By combining controlled mechanical stimulation & whole brain #imaging, @etlunsford.bsky.social revealed an essential principle 💡... Mechanosensory inputs from any directions along the body are encoded relative to the center of mass (COM)! Recalling #olfaction with odors encoded by pleasantness (4)
Reposted by Claire Wyart
Let's share @etlunsford.bsky.social's work : to survive, animals avoid drifting involuntarily in their environment. While humans rely on visual & vestibular cues, birds & fish need to sense complex flow changes of the external fluid (air/water) around them to select motor actions. How do they do?(1)
July 2, 2025 at 3:15 PM
Let's share @etlunsford.bsky.social's work : to survive, animals avoid drifting involuntarily in their environment. While humans rely on visual & vestibular cues, birds & fish need to sense complex flow changes of the external fluid (air/water) around them to select motor actions. How do they do?(1)
hi BlueSky, introducing @wyartlab.bsky.social @zebrafishrock.bsky.social "cuvée" 🍷 biodynamic organic & bubbly 2025!! Located in @institutducerveau.bsky.social 🎏 migrating in summer @sorbonne-universite.fr to observatory or in @standrewspsyneuro.bsky.social to learn #MotorControl, #morphogenesis!
July 2, 2025 at 2:54 PM
hi BlueSky, introducing @wyartlab.bsky.social @zebrafishrock.bsky.social "cuvée" 🍷 biodynamic organic & bubbly 2025!! Located in @institutducerveau.bsky.social 🎏 migrating in summer @sorbonne-universite.fr to observatory or in @standrewspsyneuro.bsky.social to learn #MotorControl, #morphogenesis!
⚡Awesome days of scientific discussions around the topic of resilient motor circuits in Parkinson's disease & underlying genetic conditions featuring Prof. Alexis Brice, Leonard Constien, Ananelle Redon, Ninon Peysson @kevinfidelin.bsky.social among others⚡
June 12, 2025 at 12:26 PM
⚡Awesome days of scientific discussions around the topic of resilient motor circuits in Parkinson's disease & underlying genetic conditions featuring Prof. Alexis Brice, Leonard Constien, Ananelle Redon, Ninon Peysson @kevinfidelin.bsky.social among others⚡
Reposted by Claire Wyart
🚨Job opportunity 🚨
The @clairewyart.bsky.social 's lab, at the @institutducerveau.bsky.social is looking for a lab manager to help us cracking the molecular underpinnings of motor circuits in vivo and across species !
The @clairewyart.bsky.social 's lab, at the @institutducerveau.bsky.social is looking for a lab manager to help us cracking the molecular underpinnings of motor circuits in vivo and across species !
June 12, 2025 at 6:51 AM
🚨Job opportunity 🚨
The @clairewyart.bsky.social 's lab, at the @institutducerveau.bsky.social is looking for a lab manager to help us cracking the molecular underpinnings of motor circuits in vivo and across species !
The @clairewyart.bsky.social 's lab, at the @institutducerveau.bsky.social is looking for a lab manager to help us cracking the molecular underpinnings of motor circuits in vivo and across species !
🧿 Excited about molecular biology & genetics 🧬🧬🧬? Wanna live in Paris? Join our team as a lab manager under the supervision of @kevinfidelin.bsky.social & myself! Personal development in professional environment is our mission. Inclusive space where proactive and playing collective people flourish 🧿
June 12, 2025 at 12:09 PM
🧿 Excited about molecular biology & genetics 🧬🧬🧬? Wanna live in Paris? Join our team as a lab manager under the supervision of @kevinfidelin.bsky.social & myself! Personal development in professional environment is our mission. Inclusive space where proactive and playing collective people flourish 🧿
Great seminar this morning scheduled this morning from Andre Brown @imperialcollegeldn.bsky.social @institutducerveau.bsky.social dont miss it !
📣SEMINAR📣 Come along @institutducerveau.bsky.social to hear Andre Brown from @imperialcollegeldn.bsky.social speak about his work on computational ethology for disease modelling and drug screening! 🪱
March 17, 2025 at 7:46 AM
Great seminar this morning scheduled this morning from Andre Brown @imperialcollegeldn.bsky.social @institutducerveau.bsky.social dont miss it !
Congrats Laura, your science (and neuronal morphologies) is (are) beautiful ✨🌳
Very grateful to @leverhulmetrust.bsky.social for funding this project @devneuro.bsky.social in collaboration with mathematician Karen Page @uclofficial.bsky.social on how neurons get their amazing shapes!
Prof @landreae.bsky.social has been awarded a @leverhulme.bsky.social project grant to uncover the rules behind neuronal development #neuroskyence
www.kcl.ac.uk/news/laura-a...
www.kcl.ac.uk/news/laura-a...
December 14, 2024 at 12:22 PM
Congrats Laura, your science (and neuronal morphologies) is (are) beautiful ✨🌳