Claire Wyart
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clairewyart.bsky.social
Claire Wyart
@clairewyart.bsky.social
1.8K followers 300 following 13 posts
Team Leader @Paris Brain Institute &
Inserm Director. Fascinated by navigation, movement and brain body interactions. Passion for interdisciplinary training. Knows biodiversity and climate demand changing my game... more on wyartlab.org
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clairewyart.bsky.social
Hey #motorcontrol researchers! @jul-bouvier.bsky.social, LeMouel & I organize *Searching for principles in Motor Control* Paris Sept 23-24, 25 @sorbonne-universite.fr @institutducerveau.bsky.social @neuropsi.bsky.social: Submit Abstract for Posters by Aug 31! motorconference.sciencesconf.org?lang=en
August 20, 2025 at 12:56 PM
clairewyart.bsky.social
hi BlueSky, introducing @wyartlab.bsky.social @zebrafishrock.bsky.social "cuvée" 🍷 biodynamic organic & bubbly 2025!! Located in @institutducerveau.bsky.social 🎏 migrating in summer @sorbonne-universite.fr to observatory or in @standrewspsyneuro.bsky.social to learn #MotorControl, #morphogenesis!
July 2, 2025 at 2:54 PM
clairewyart.bsky.social
⚡Awesome days of scientific discussions around the topic of resilient motor circuits in Parkinson's disease & underlying genetic conditions featuring Prof. Alexis Brice, Leonard Constien, Ananelle Redon, Ninon Peysson @kevinfidelin.bsky.social among others⚡
June 12, 2025 at 12:26 PM
clairewyart.bsky.social
🧿 Excited about molecular biology & genetics 🧬🧬🧬? Wanna live in Paris? Join our team as a lab manager under the supervision of @kevinfidelin.bsky.social & myself! Personal development in professional environment is our mission. Inclusive space where proactive and playing collective people flourish 🧿
June 12, 2025 at 12:09 PM
clairewyart.bsky.social
Motor afficionados: Don't miss great talks coming up this week #CAJAL #Training @univbordeaux.bsky.social #MotorControl featuring in particular @olekiehn.bsky.social #FENS president & Brain Prize 2022 showing his contribution to understanding *Circuits for Movements* on Thursday Dec 5th at 11 AM ✨
December 1, 2024 at 10:49 PM
clairewyart.bsky.social
So MUCH fun organizing the Cajal Brain Prize Motor School in the honour of Silvia Arber, Martyn Goulding and Ole Kiehn for 20 early career students and postdocs wanting to learn by making their hands dirty when comparing 🐸🎏 🐭🐒 🚶‍♂️locusts, frogs, fish, mice, macaques, humans and more!
November 21, 2024 at 11:44 PM
clairewyart.bsky.social
📣 Time to register to the 7th European Zebra 🐟 Principle Investigator Meeting to be held in Paris Brain Institute, April 2- 5, 2025. Early 🦜 until Dec 15th, 2024. Abstract submission is now open. Apply! Share latest results & fun ! 👉 lnkd.in/e4pDe7uh #zebrafish www.europeanzebrafishpimeeting.com
November 16, 2024 at 10:18 PM
clairewyart.bsky.social
Individuality is fascinating. We found how to quantify variability among individuals by identifying long-lasting motor strategies during navigation. Work of Dr. Gautam Sridhar and Dr. Antonio Costa in collab with João Marques @daniobrain.bsky.social out today in #PNAS ! www.pnas.org/doi/10.1073/...
When animals deploy motor strategies to navigate and adapt to changing environments and their own experiences, their behavior is highly variable across multiple timescales and from one animal to another. Using high-fidelity Markov models of behavior, we reveal the main modes along which zebrafish generate motor strategies in different environments. We uncover essential principles underlying navigation and reveal that an individual’s past experience, or its current inner state alters preferences for long-lasting motor strategies. This study sets the stage for general approaches to dissect the origin of variability of navigation among individuals. --- To reveal structure in individual variability, we build Markov models of action sequences that bridge across timescales and enable the comparison of behavioral phenotypes among individuals. Applied to zebrafish responding to diverse sensory cues, we uncover a hierarchy of long-lived motor strategies, dominated by changes in orientation distinguishing cruising versus wandering. While fish cruise in the light, they wander in response to aversive stimuli, or in search for appetitive prey. As our method encodes the behavioral dynamics of each individual fish in the transitions among coarse-grained motor strategies, we use it to uncover a hierarchical structure in the phenotypic variability that reflects exploration–exploitation trade-offs. The major source of variation among fish is driven by prior or immediate exposure to prey that induces exploitation phenotypes. A large degree of variability not explained by environmental cues unravels hidden states that override the sensory context to induce contrasting exploration–exploitation phenotypes. Altogether, by extracting the timescales of motor strategies deployed during navigation, our approach exposes structure among individuals and reveals internal states tuned by prior experience.
November 16, 2024 at 9:22 PM