Claudia Mimoso
@camimoso.bsky.social
YSM Science Fellow @YaleGenetics
PhD @BBS_Harvard @AdelmanLab
Cornell University ’17
PhD @BBS_Harvard @AdelmanLab
Cornell University ’17
Reposted by Claudia Mimoso
Undergraduates who are interested in summer research please consider the HHMI Cech Fellows Program. There are many great HHMI labs to choose from including ours!
Calling all rising juniors & seniors: Interested in biological or biomedical research? Applications for our ’26 Summer Undergraduate Research Experience Program are now open! Nine weeks, hands-on research, & mentorship from some of the nation’s top scientists — learn more: bit.ly/CechFellows
Summer Undergraduate Research Experience | HHMI
The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.
bit.ly
November 21, 2025 at 6:36 PM
Undergraduates who are interested in summer research please consider the HHMI Cech Fellows Program. There are many great HHMI labs to choose from including ours!
Reposted by Claudia Mimoso
Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526
HMS - Postdoctoral Fellow in BCMP, Brown Lab
We invite applicants for a postdoctoral fellow position in the Brown lab at Harvard Medical School in Boston, Massachusetts. The Brown lab uses structural, biophysical, and biochemical approaches to d...
academicpositions.harvard.edu
November 18, 2025 at 8:05 PM
Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526
Reposted by Claudia Mimoso
Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp
Proteome-wide in silico screening for human protein-protein interactions
Protein-protein interactions (PPIs) drive virtually all biological processes, yet most PPIs have not been identified and even more remain structurally unresolved. We developed a two-step computational...
biorxiv.org
November 12, 2025 at 9:26 PM
Thrilled to share that the final piece of my PhD work is now on bioRxiv! biorxiv.org/content/10.1... With support from @nvidia and the @NSF, we used AlphaFold to screen 1.6M+ protein pairs, revealing thousands of potential novel PPIs. All data can be viewed at predictomes.org/hp
Reposted by Claudia Mimoso
KATMAP infers splicing factor activity and regulatory targets from knockdown data - @daspliceisright.bsky.social go.nature.com/47ycrMJ
KATMAP infers splicing factor activity and regulatory targets from knockdown data - Nature Biotechnology
A biophysical model uses knockdown or overexpression data to infer splicing factor activity.
go.nature.com
November 4, 2025 at 3:13 PM
KATMAP infers splicing factor activity and regulatory targets from knockdown data - @daspliceisright.bsky.social go.nature.com/47ycrMJ
Reposted by Claudia Mimoso
"TOMORROW @yaleneuro.bsky.social @kavliatyale.bsky.social Yale present #SYNAPSES, our senior postdoc symposium! 🙌
Hear from four incredible researchers 👩🔬🥼 as they share their latest discoveries and insights! 🗣️
You won't want to miss it! 🗓️"
Hear from four incredible researchers 👩🔬🥼 as they share their latest discoveries and insights! 🗣️
You won't want to miss it! 🗓️"
October 22, 2025 at 2:24 PM
"TOMORROW @yaleneuro.bsky.social @kavliatyale.bsky.social Yale present #SYNAPSES, our senior postdoc symposium! 🙌
Hear from four incredible researchers 👩🔬🥼 as they share their latest discoveries and insights! 🗣️
You won't want to miss it! 🗓️"
Hear from four incredible researchers 👩🔬🥼 as they share their latest discoveries and insights! 🗣️
You won't want to miss it! 🗓️"
Reposted by Claudia Mimoso
Check out the latest work from our lab, led by Arash Latifkar @ara-latifkar.bsky.social , www.biorxiv.org/content/10.1...
mRNA poly(A)-tail length is a battleground for coronavirus–host competition
Most eukaryotic mRNAs contain a poly(A) tail, which in post-embryonic cells enhances their stability. Many cytoplasmic RNA viruses also harbor poly(A) tails on their genomic RNA and mRNAs. Here, we re...
www.biorxiv.org
October 13, 2025 at 7:44 PM
Check out the latest work from our lab, led by Arash Latifkar @ara-latifkar.bsky.social , www.biorxiv.org/content/10.1...
Reposted by Claudia Mimoso
Thrilled to share our work on transcription initiation and termination being spatially coordinated out today in Science! www.science.org/doi/10.1126/...
mRNA initiation and termination are spatially coordinated
Transcriptional initiation and termination decisions drive messenger RNA (mRNA) isoform diversity but the relationship between them remains poorly understood. By systematically profiling joint usage o...
www.science.org
October 10, 2025 at 6:14 PM
Thrilled to share our work on transcription initiation and termination being spatially coordinated out today in Science! www.science.org/doi/10.1126/...
Reposted by Claudia Mimoso
If you’re interested in exploring the relationship between chromatin organization and epigenetic memory using chromatin tracing microscopy, my group is recruiting a talented PhD student 🥳
🚨 Please share! We are seeking motivated PhD students who wish to work at the intersection of molecular life sciences and computational sciences.
#IMPRS #IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de
Check out our projects and apply by Jan 7th, 2026!
www.molgen.mpg.de/IMPRSPhDproj...
#IMPRS #IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de
Check out our projects and apply by Jan 7th, 2026!
www.molgen.mpg.de/IMPRSPhDproj...
October 8, 2025 at 5:05 PM
If you’re interested in exploring the relationship between chromatin organization and epigenetic memory using chromatin tracing microscopy, my group is recruiting a talented PhD student 🥳
Reposted by Claudia Mimoso
Historically, viruses were thought to primarily use host cell's translational machinery. New work from @harvardcellbio.bsky.social faculty Amy Lee reveals that a giant DNA virus encodes its own IF4F initiation complex, suggesting an unexpected evolutionary innovation. www.biorxiv.org/content/10.1...
Giant DNA viruses encode a hallmark translation initiation complex of eukaryotic life
In contrast to living organisms, viruses were long thought to lack protein synthesis machinery and instead depend on host factors to translate viral transcripts. Here, we discover that giant DNA virus...
www.biorxiv.org
October 2, 2025 at 6:10 PM
Historically, viruses were thought to primarily use host cell's translational machinery. New work from @harvardcellbio.bsky.social faculty Amy Lee reveals that a giant DNA virus encodes its own IF4F initiation complex, suggesting an unexpected evolutionary innovation. www.biorxiv.org/content/10.1...
Reposted by Claudia Mimoso
Out in Cell Genomics: A comprehensive analysis of the cell-type-specific effects of CHD8 loss of function on gene expression in the embryonic and juvenile mouse cortex. Thread 🧵:
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development
Yim et al. use single-cell transcriptomics to elucidate the molecular outcomes of
Chd8 haploinsufficiency in the mouse cortex. Their results provide insight into dynamic,
cell-type-biased transcriptio...
www.cell.com
September 23, 2025 at 5:18 PM
Out in Cell Genomics: A comprehensive analysis of the cell-type-specific effects of CHD8 loss of function on gene expression in the embryonic and juvenile mouse cortex. Thread 🧵:
www.cell.com/cell-genomic...
www.cell.com/cell-genomic...
Reposted by Claudia Mimoso
How are RNAs sorted for export vs. degradation in the nucleus? In collaboration with @heick.bsky.social’s lab we (@clemensplaschka.bsky.social and @juliusbrennecke.bsky.social labs) discovered a direct mechanistic link between the export and decay machineries: www.biorxiv.org/content/10.1... (1/x)
Molecular basis of polyadenylated RNA fate determination in the nucleus
Eukaryotic genomes generate a plethora of polyadenylated (pA+) RNAs[1][1],[2][2], that are packaged into ribonucleoprotein particles (RNPs). To ensure faithful gene expression, functional pA+ RNPs, in...
www.biorxiv.org
September 22, 2025 at 11:23 PM
How are RNAs sorted for export vs. degradation in the nucleus? In collaboration with @heick.bsky.social’s lab we (@clemensplaschka.bsky.social and @juliusbrennecke.bsky.social labs) discovered a direct mechanistic link between the export and decay machineries: www.biorxiv.org/content/10.1... (1/x)
Reposted by Claudia Mimoso
📣 Our department is hiring an Assistant Professor in Evolutionary Cell and Molecular Biology to join the @weillinstitute.bsky.social PLS spread the word!
academicjobsonline.org/ajo/jobs/30607
academicjobsonline.org/ajo/jobs/30607
Cornell University, Molecular Biology & Genetics
Job #AJO30607, WDR-00055221 Assistant Professor, Molecular Biology & Genetics, Cornell University, Ithaca, New York, US
academicjobsonline.org
September 23, 2025 at 12:50 PM
📣 Our department is hiring an Assistant Professor in Evolutionary Cell and Molecular Biology to join the @weillinstitute.bsky.social PLS spread the word!
academicjobsonline.org/ajo/jobs/30607
academicjobsonline.org/ajo/jobs/30607
Reposted by Claudia Mimoso
Registration and abstract submission is open for the 10th annual Danish RNA Society meeting 🇩🇰 - this year in Aarhus!
Deadline is October 1st
danish-rna-society.nemtilmeld.dk/8/
Deadline is October 1st
danish-rna-society.nemtilmeld.dk/8/
September 10, 2025 at 6:15 PM
Registration and abstract submission is open for the 10th annual Danish RNA Society meeting 🇩🇰 - this year in Aarhus!
Deadline is October 1st
danish-rna-society.nemtilmeld.dk/8/
Deadline is October 1st
danish-rna-society.nemtilmeld.dk/8/
Reposted by Claudia Mimoso
As part of this grant, I have a vacancy out for a PhD student to join our super nice team. It closes on September 9 (Tuesday).
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
PhD position in Gene Regulation
Are you excited about studying the crucial process of transcription? Join our supportive, young and growing team!
www.uu.nl
September 4, 2025 at 11:48 AM
As part of this grant, I have a vacancy out for a PhD student to join our super nice team. It closes on September 9 (Tuesday).
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
Reposted by Claudia Mimoso
Thrilled to be one of the ERC StG awardees this year! It will allow my team to further delve into the puzzle of what regulates the fate of RNA Polymerase II during early elongation: will it terminate early, or elongate happily ever after?
📣 The ERC Starting Grant call results are out!
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025!
➡️ buff.ly/IsafuFh
#FrontierResearch 🇪🇺#EUfunded #HorizonEurope
September 4, 2025 at 11:48 AM
Thrilled to be one of the ERC StG awardees this year! It will allow my team to further delve into the puzzle of what regulates the fate of RNA Polymerase II during early elongation: will it terminate early, or elongate happily ever after?
Reposted by Claudia Mimoso
JUST IN: Harvard won summary judgment against the Trump administration with the court finding that the admin violated Harvard's 1st amend. rights. The court has vacated the funding freeze orders and termination letters and issued a permanent injunction.
storage.courtlistener.com/recap/gov.us...
storage.courtlistener.com/recap/gov.us...
![[cite_start]A screenshot of the first page of a court document from the United States District Court for the District of Massachusetts[cite: 3]. [cite_start]The document is titled "MEMORANDUM AND ORDER" [cite: 43] [cite_start]and was filed on September 3, 2025[cite: 1].
The document lists two related civil actions:
* [cite_start]**Civil Action No. 25-cv-11048-ADB**: President and Fellows of Harvard College, et al., Plaintiffs, v. United States Department of Health and Human Services, et al., Defendants[cite: 4, 5, 14, 17, 21].
* [cite_start]**Civil Action No. 25-cv-10910-ADB**: American Association of University Professors - Harvard Chapter, et al., Plaintiffs, v. United States Department of Justice, et al., Defendants[cite: 22, 23, 24, 26, 27, 36].
[cite_start]The order is from Judge Burroughs, D.J.[cite: 44]. [cite_start]The text begins by identifying the plaintiffs in the consolidated cases[cite: 45].](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:sefgphqp2xqwh2hawaixykwz/bafkreiaefziiwcjq4laze5iymzn45j4qfm3lc226u27qrdhlxqxjixzxae@jpeg)
September 3, 2025 at 8:35 PM
JUST IN: Harvard won summary judgment against the Trump administration with the court finding that the admin violated Harvard's 1st amend. rights. The court has vacated the funding freeze orders and termination letters and issued a permanent injunction.
storage.courtlistener.com/recap/gov.us...
storage.courtlistener.com/recap/gov.us...
Reposted by Claudia Mimoso
Gift link.
Harvard Secures a Court Victory in Its Fight With Trump
www.nytimes.com
September 3, 2025 at 8:46 PM
Gift link.
Reposted by Claudia Mimoso
We're super excited to announce the entire lineup for the Fall season of Fragile Nucleosome Seminars, starting on Sept 10th at 1200 EDT / 1600 UTC with @gracebower.bsky.social and @creminslab.bsky.social!
register here for the entire series: us06web.zoom.us/webinar/regi...
register here for the entire series: us06web.zoom.us/webinar/regi...
September 1, 2025 at 2:59 PM
We're super excited to announce the entire lineup for the Fall season of Fragile Nucleosome Seminars, starting on Sept 10th at 1200 EDT / 1600 UTC with @gracebower.bsky.social and @creminslab.bsky.social!
register here for the entire series: us06web.zoom.us/webinar/regi...
register here for the entire series: us06web.zoom.us/webinar/regi...
Reposted by Claudia Mimoso
shocking to read over and over the stories of close colleagues who can't run their lab anymore. I know Karen well and it's heartbreaking. Also #PIinthelab! www.washingtonpost.com/education/20...
Harvard’s research is shrinking amid the Trump administration’s freeze
Even if grants at Harvard are suddenly restored, there is deep-rooted uncertainty about the damage already done and the future of basic science research in the U.S.
www.washingtonpost.com
August 25, 2025 at 7:42 PM
shocking to read over and over the stories of close colleagues who can't run their lab anymore. I know Karen well and it's heartbreaking. Also #PIinthelab! www.washingtonpost.com/education/20...
Reposted by Claudia Mimoso
NIH: After review, we note that you have a large unspent balance on your grant. Please explain immediately.
me: well, uh, yeah, one reason we're not spending on that grant is because NIH terminated it in May along with all the rest of federal funding to Harvard, maybe you don't remember
me: well, uh, yeah, one reason we're not spending on that grant is because NIH terminated it in May along with all the rest of federal funding to Harvard, maybe you don't remember
August 21, 2025 at 3:13 PM
NIH: After review, we note that you have a large unspent balance on your grant. Please explain immediately.
me: well, uh, yeah, one reason we're not spending on that grant is because NIH terminated it in May along with all the rest of federal funding to Harvard, maybe you don't remember
me: well, uh, yeah, one reason we're not spending on that grant is because NIH terminated it in May along with all the rest of federal funding to Harvard, maybe you don't remember
Reposted by Claudia Mimoso
New paper on the role of H3K4me3 at enhancers! We (led by Haoming Yu) used dCas9 epigenome editing to add H3K4me3 to intergenic enhancers. This was (1) sufficient to turn up transcription at open, active regions and (2) has no effect on target gene transcription. genesdev.cshlp.org/content/earl...
H3K4me3 amplifies transcription at intergenic active regulatory elements
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
August 20, 2025 at 1:29 AM
New paper on the role of H3K4me3 at enhancers! We (led by Haoming Yu) used dCas9 epigenome editing to add H3K4me3 to intergenic enhancers. This was (1) sufficient to turn up transcription at open, active regions and (2) has no effect on target gene transcription. genesdev.cshlp.org/content/earl...
Reposted by Claudia Mimoso
The Vlaming lab is expanding! If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
My biased opinion: exciting topic, super nice colleagues, and great research environment in a lovely city.
My biased opinion: exciting topic, super nice colleagues, and great research environment in a lovely city.
PhD position in Gene Regulation
Are you excited about studying the crucial process of transcription? Join our supportive, young and growing team!
www.uu.nl
August 15, 2025 at 10:22 AM
The Vlaming lab is expanding! If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...
My biased opinion: exciting topic, super nice colleagues, and great research environment in a lovely city.
My biased opinion: exciting topic, super nice colleagues, and great research environment in a lovely city.
Reposted by Claudia Mimoso
🧑🔬I am thrilled to share I am starting my lab as an asst. prof. in the Dept. of Molecular and Cellular Biosciences at the University of Cincinnati. 🔬We will be hiring soon, so if you're interested in Mechanisms of Transcription Termination, watch this space 👀 🥳
www.clarehall.cam.ac.uk/news/dr-juan...
www.clarehall.cam.ac.uk/news/dr-juan...
Dr Juan Rodriguez-Molina appointed Assistant Professor at the University of Cincinnati - Clare Hall
Warmest congratulations to Dr Juan Rodriguez-Molina, Clare Hall Associate, who has been appointed Assistant Professor in the Department of Molecular and Cellular Biosciences at the University of Cinci...
www.clarehall.cam.ac.uk
August 13, 2025 at 1:41 PM
🧑🔬I am thrilled to share I am starting my lab as an asst. prof. in the Dept. of Molecular and Cellular Biosciences at the University of Cincinnati. 🔬We will be hiring soon, so if you're interested in Mechanisms of Transcription Termination, watch this space 👀 🥳
www.clarehall.cam.ac.uk/news/dr-juan...
www.clarehall.cam.ac.uk/news/dr-juan...
Reposted by Claudia Mimoso
📢 Save the Date!
The 13th Yale RNA Center Annual Retreat returns this fall:
🗓️ November 7, 2025
Join us for a full day of cutting-edge RNA science and community.
Stay tuned for details on speakers, sessions, and registration.
The 13th Yale RNA Center Annual Retreat returns this fall:
🗓️ November 7, 2025
Join us for a full day of cutting-edge RNA science and community.
Stay tuned for details on speakers, sessions, and registration.
August 5, 2025 at 7:09 PM
📢 Save the Date!
The 13th Yale RNA Center Annual Retreat returns this fall:
🗓️ November 7, 2025
Join us for a full day of cutting-edge RNA science and community.
Stay tuned for details on speakers, sessions, and registration.
The 13th Yale RNA Center Annual Retreat returns this fall:
🗓️ November 7, 2025
Join us for a full day of cutting-edge RNA science and community.
Stay tuned for details on speakers, sessions, and registration.